36,098 results match your criteria conjunctival

Using Multivariate Analyses To Explore Disease Progression of Finch Mycoplasmosis.

J Wildl Dis 2021 May 12. Epub 2021 May 12.

Department of Ecology, Evolution, and Organismal Biology, Iowa State University, 251 Bessey Hall, 2200 Osborne Drive, Ames, Iowa 50011, USA.

Lesion severity scales have been developed for a number of wildlife diseases causing external pathology. Perhaps the best known and most widely used scoring system has been developed for finch mycoplasmosis in which observers measure conjunctival pathology along a four-point scale of increasing severity. We developed novel techniques to characterize variation in host phenotype based on occupancy of multidimensional trait space (disease space). Read More

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A Rare Case of Conjunctival Melanoma with Orbital Invasion.

Nepal J Ophthalmol 2020 Jul;12(24):352-354

Universidad del Valle; Ocular Health Research Group, Grupo de Investigación en Salud Ocular (GISOC-UV), Hospital Universitario del Valle, Universidad del Valle, Cali, Colombia.

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Anaemic retinopathy in megaloblastic anaemia.

Nepal J Ophthalmol 2020 Jul;12(24):313-316

Alluri Seetharamaraju Academy of Medical Sciences and Hospital, Eluru, West Godavari district, Andhra Pradesh, India.

Introduction: Anaemias are the commonest haematological disorders which cause ocular manifestations. With the progression of disease, retinal haemorrhages, dilated and tortuous veins, cotton wool spots may occur in the ocular fundus.

Case: An 18-year-old female patient presented to our out patient department with the sudden, painless, non-progressive blurring of vision in both eyes (best-corrected visual acuity in the right eye is 6/60, and left eye is 6/36) for two days. Read More

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Secondary angle closure glaucoma due to posterior scleritis in a case of empty sella syndrome.

Nepal J Ophthalmol 2020 Jul;12(24):308-312

Sita Lakshmi Glaucoma Center, Anand Eye Institute.

Introduction: We frequently come upon cases of posterior scleritis with secondary angle closure glaucoma. However, it can pose a diagnostic dilemma in a patient with bilateral disc edema along with unilateral angle closure glaucoma due to posterior scleritis.

Case: We report a case of a 25 - year old male, who presented with the complaints of pain, redness and blurring of vision in the left eye for the last 3 days. Read More

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Profile of Ophthalmic Tumors in Adult Nepalese Population in Central Nepal.

Nepal J Ophthalmol 2020 Jul;12(24):270-280

Geta Eye Hospital, Dhangadhi, Nepal.

Introduction: Ophthalmic tumors cover benign and malignant tumors of eyelids, conjunctiva, globe, and orbit. There is limited literature on ophthalmic tumors in Nepal. The objective of the study was to find the relative frequency of various ophthalmic tumors in the adult Nepalese population in Central Nepal. Read More

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Use of Polarized Light in the Diagnosis of "Fuzz" Granuloma in the Conjunctiva of a Child.

Case Rep Ophthalmol 2021 Jan-Apr;12(1):239-242. Epub 2021 Apr 12.

Department of Laboratory Medicine, Geisinger Medical Center, Danville, Pennsylvania, USA.

Synthetic fiber granulomas, also known as "Teddy Bear" granulomas or "Fuzz Ball granulomas," are usually seen in childhood. We present a case of a 5-year-old child with a "Fuzz Ball" granuloma of the conjunctiva. The resected specimen was processed routinely. Read More

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Peripapillary Choroidal Neovascular Membrane Secondary to Sarcoidosis-Related Panuveitis: Treatment with Aflibercept and Ranibizumab with a 50-month Follow-Up.

Case Rep Ophthalmol 2021 Jan-Apr;12(1):186-192. Epub 2021 Apr 12.

2nd Department of Ophthalmology, Aristotle University of Thessaloniki, Papageorgiou General Hospital, Thessaloniki, Greece.

A case of peripapillary choroidal neovascular membrane (PCNM) secondary to sarcoidosis-related panuveitis successfully treated with anti-vascular endothelial growth factor (anti-VEGF) agents and systemic immunomodulatory therapy is reported. Diagnosis and follow-up were based on fundoscopic, optical coherence tomography as well as fluorescein angiography findings. A 45-year-old female patient presented with sudden onset bilateral blurring of vision. Read More

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Conjunctival Chemosis and Annular Ciliochoroidal Detachments Detected by Anterior-Segment Optical Coherence Tomography in a Case of Systemic Lupus Erythematosus.

Case Rep Ophthalmol 2021 Jan-Apr;12(1):154-158. Epub 2021 Apr 12.

Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo, Japan.

A 61-year-old Japanese woman presented to our hospital for treatment of systemic serositis associated with systemic lupus erythematosus (SLE). At the initial ophthalmologic examination, her best-corrected visual acuity was 1.2 and 0. Read More

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Necrotizing Infiltrating Conjunctiva and Tenon's Capsule: A Case Report.

Case Rep Ophthalmol 2021 Jan-Apr;12(1):146-149. Epub 2021 Apr 12.

Department of Ophthalmology, Federal University of São Paulo, Sao Paulo, Brazil.

We report a case of a patient with necrotizing infection of the conjunctiva and Tenon's capsule caused by , a rare and atypical ophthalmologic condition. A 50-years-old male patient with acute red-eye, purulent discharge, and pain diagnosed with post-septal cellulitis presented with a yellowish and dense membrane covering the ocular surface with necrotic Tenon's capsule. Patient was hospitalized, and intravenous antibiotics were initiated (ceftriaxone and clindamycin). Read More

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Granulomatosis with Polyangiitis with Ocular Manifestations.

Case Rep Ophthalmol 2021 Jan-Apr;12(1):98-104. Epub 2021 Apr 6.

Postgraduate Education Department, Kazakh Eye Research Institute, Almaty, Kazakhstan.

Granulomatosis with polyangiitis (GPA) is a granulomatous-necrotic systemic vasculitis with a lesion of predominantly the upper and lower respiratory tracts at the onset of the disease (vasculitis, accompanied by granulomatous inflammation), and subsequently renal (glomerulonephritis). In addition, GPA may manifest as inflammation of small arteries and veins. Despite many years of study of this disease, the etiology of GPA remains unknown. Read More

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Characteristics and recurrence of pterygium in Saudi Arabia: a single center study with a long follow-up.

BMC Ophthalmol 2021 May 11;21(1):207. Epub 2021 May 11.

Department of Ophthalmology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

Background: This study described the clinical features of patients with pterygium and analyzed the recurrence rate of conjunctival autografting alone, conjunctival autografting combined with intraoperative mitomycin C, and amniotic membrane grafting.

Methods: A retrospective cohort study of primary pterygium was conducted between January 2017 and February 2020. Factors associated with pterygium severity and recurrence were analyzed by univariate analysis and logistic regression models. Read More

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An Eye on COVID-19: A Meta-analysis of Positive Conjunctival Reverse Transcriptase-Polymerase Chain Reaction and SARS-CoV-2 Conjunctivitis Prevalence.

Optom Vis Sci 2021 May 7. Epub 2021 May 7.

Atrius Health, Newton, Massachusetts

Significance: This analysis and review demonstrate that, although emerging data indicate that the prevalence of severe acute respiratory coronavirus 2 (SARS-CoV-2) on the ocular surface and coronavirus disease 2019 (COVID-19) conjunctivitis is rare, the ocular surface remains of interest as a potential inoculation and transmission site for SARS-CoV-2. Continued safety precautions should be taken as more data become available.Coronavirus disease 2019, caused by SARS-CoV-2, is a novel, global pandemic that has infected millions and, up to this point, caused more than two million fatalities worldwide. Read More

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Hyperbilirubinemia with mild COVID-19 patient: A case report.

Int J Surg Case Rep 2021 May 3;82:105958. Epub 2021 May 3.

Department of critical care nursing, College of Nursing, Urmia University of Medical Science, Iran.

Introduction And Importance: Increased total serum bilirubin rarely reported in mild COVID-19 patients. It occurs mostly in severe cases, particularly in those who have liver diseases and admitted to an intensive care unit. The main cause of increased liver biochemistries in Covid-19 patients related to used drugs, the presence of the ACE2 receptor in the liver, and robust inflammatory response. Read More

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Changes in peri-ocular anatomy and physiology in pseudoexfoliation syndrome (Review).

Exp Ther Med 2021 Jun 19;21(6):650. Epub 2021 Apr 19.

Laboratory of Clinical Virology, Medical School, University of Crete, Heraklion 71003, Greece.

Pseudoexfoliation syndrome (PEX) is characterized by the deposition of proteinaceous material in the anterior ocular segment (resulting in ophthalmic pathologies such as glaucoma and increased risk of complications in cataract surgery), but also by several systemic manifestations. The involvement of peri-ocular tissues in PEX, including the eyelid skin, lacrimal gland, conjunctiva, orbital fat and vessels, as well as the optic nerve, has been reported by several previous studies. The peri-ocular effects of PEX include the development of eyelid laxity, conjunctival chalasis, tear film abnormalities, pronounced orbital fat atrophy in response to the administration of prostaglandin analogues in pseudoexfoliative glaucoma, deficient orbital vascular supply and biomechanical changes in both the eyeball and the optic nerve. Read More

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Pro-Resolving Mediator Annexin A1 Regulates Intracellular Ca and Mucin Secretion in Cultured Goblet Cells Suggesting a New Use in Inflammatory Conjunctival Diseases.

Front Immunol 2021 22;12:618653. Epub 2021 Apr 22.

Schepens Eye Research institute/Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, United States.

The amount of mucin secreted by conjunctival goblet cells is regulated to ensure the optimal level for protection of the ocular surface. Under physiological conditions lipid specialized pro-resolving mediators (SPM) are essential for maintaining tissue homeostasis including the conjunctiva. The protein Annexin A1 (AnxA1) can act as an SPM. Read More

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Case Series: High-resolution Optical Coherence Tomography as an Optical Biopsy in Ocular Surface Squamous Neoplasia.

Optom Vis Sci 2021 May 8. Epub 2021 May 8.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida Department of Ophthalmology, Miami Veterans Administration Medical Center, Miami, Florida

Significance: Ocular surface squamous neoplasias are superficial tumors of the cornea and conjunctiva that can be sight threatening if neglected. Therefore, accurate noninvasive diagnostic modalities are needed.

Purpose: The purpose of this case series was to describe the hallmark features of ocular surface squamous neoplasia on high-resolution optical coherence tomography (HR-OCT) imaging and its use in the evaluation and management of superficial ocular tumors. Read More

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Demographic and lifestyle risk factors of dry eye disease subtypes: A cross-sectional study.

Ocul Surf 2021 May 6. Epub 2021 May 6.

Optometry and Vision Sciences, College of Health and Life Sciences, Aston University, Birmingham, UK; Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, New Zealand. Electronic address:

Purpose: To evaluate demographic and lifestyle factors associated with aqueous deficient and evaporative dry eye disease.

Methods: A total of 1125 general public visitors (707 females, mean ± SD age, 33 ± 21, range 5-90 years) at the Royal Society Summer Science Exhibition were recruited in a cross-sectional study. A demographic and lifestyle factor questionnaire was administered, and dry eye symptomology (DEQ-5 score), ocular surface characteristics (conjunctival hyperaemia, and infrared meibography), and tear film parameters (tear meniscus height, non-invasive breakup time, and lipid layer grade) were evaluated for each participant within a single session. Read More

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Analysis of surgical outcome after upper eyelid surgery by computer vision algorithm using face and facial landmark detection.

Graefes Arch Clin Exp Ophthalmol 2021 May 8. Epub 2021 May 8.

Department of Ophthalmology, Yeditepe University Medical School, Istanbul, Turkey.

Purpose: To evaluate the postoperative changes with a computer vision algorithm for anterior full-face photographs of patients who have undergone upper eyelid blepharoplasty surgery with, or without, a Müller's muscle-conjunctival resection (MMCR).

Methods: All patients who underwent upper eyelid blepharoplasty surgery (Group I), or upper eyelid blepharoplasty with MMCR (Group II) were included. Both preoperative and 6-month postoperative anterior full-face photographs of 55 patients were analyzed. Read More

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Mascara-induced nasolacrimal duct obstruction.

BMJ Case Rep 2021 May 7;14(5). Epub 2021 May 7.

Department of Ophthalmology, Addenbrooke's Hospital, Cambridge, UK.

A 35-year-old woman underwent left external dacryocystorhinostomy (DCR) following a recent bout of left acute dacryocystitis. She had a right DCR 14 years earlier. Her relatively young age of presentation prompted suspicion of secondary nasolacrimal duct obstruction and, although the left lacrimal sac appeared macroscopically normal peroperatively, a lacrimal sac biopsy was taken. Read More

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Carotid-Cavernous Sinus Fistula Masquerading as Thyroid Eye Disease.

Cureus 2021 Apr 2;13(4):e14261. Epub 2021 Apr 2.

Department of Ophthalmology, Division of Oculofacial Plastic & Orbital Surgery, Gavin Herbert Eye Institute, University of California, Irvine, Irvine, USA.

A 29-year-old man with a medical and social history notable for smoking presented with progressive orbital congestion, conjunctival injection, and extraocular muscle enlargement consistent with thyroid eye disease (TED). On ophthalmologic examination, tortuous episcleral vessels and blood in Schlemm's canal on gonioscopy clued an alternative diagnosis. Cavernous sinus enhancement on computed tomography also suggested a retro-orbital process. Read More

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Ehlers-Danlos syndrome presenting as cystic lung disease with recurrent pneumothorax: a case report.

Respirol Case Rep 2021 May 28;9(5):e00747. Epub 2021 Apr 28.

Department of Pulmonology and Critical Care Medicine, Asan Medical Center University of Ulsan College of Medicine Seoul Republic of Korea.

A 19-year-old male patient was referred to our hospital for recurrent pneumothorax. He previously experienced seven episodes of pneumothorax refractory to conventional treatment including pleurodesis and wedge resection. On admission, chest computed tomography scan showed multiple cystic lesions with surrounding ground-glass opacities and several nodules in both lungs. Read More

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The genetic diversity of human papillomavirus types from the species Gammapapillomavirus 15: HPV135, HPV146, and HPV179.

PLoS One 2021 6;16(5):e0249829. Epub 2021 May 6.

Faculty of Medicine, Institute of Microbiology and Immunology, University of Ljubljana, Ljubljana, Slovenia.

Objectives: To determine the prevalence, viral load, tissue tropism, and genetic variability of novel human papillomavirus (HPV) type 179, which is etiologically associated with sporadic cases of common warts in immunocompromised patients, and phylogenetically related HPV types 135 and 146.

Methods: The representative collection of 850 HPV-associated clinical samples (oral/nasopharyngeal/anal, archival specimens of oral/oropharyngeal/conjunctival/cervical/skin cancer, benign lesions of the larynx/conjunctiva/skin, and eyebrows), obtained from immunocompetent individuals, was tested for the presence of HPV179, HPV135, and HPV146 using type-specific real-time PCRs. To assess the genetic diversity of the HPVs investigated in the non-coding long control region (LCR), several highly sensitive nested PCR protocols were developed for each HPV type. Read More

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The Presence of SARS-CoV-2 in Conjunctival Secretions of COVID-19 Patients.

Ocul Immunol Inflamm 2021 May 5:1-4. Epub 2021 May 5.

Department of Chest Diseases, University of Health Science Adana City Training and Research Hospital, Adana, Turkey.

: To evaluate the presence of SARS-CoV-2 in conjunctival secretions of COVID-19 patients.: In this retrospective study, the records were examined of patients who were treated in the hospital with the diagnosis of COVID-19 between March-May 2020 and were referred to the eye clinic due to ocular symptoms. Conjunctival swabs from both confirmed and suspected COVID-19 cases during hospitalization were analyzed. Read More

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Surgical outcomes with high and low pulse energy femtosecond laser systems for cataract surgery.

Sci Rep 2021 May 4;11(1):9525. Epub 2021 May 4.

Universal Eye Center, Taipei, Taiwan, Republic of China.

Currently, there is no clear consensus in cataract surgery if low compared to high energy femto-lasers may enable better capsulotomy quality and induce lower inflammatory response. Therefore, the aim of this study was to compare the intra-operative outcomes achieved with high and low pulse energy femtosecond laser systems for cataract surgery. The charts of 200 eyes of 200 patients aged 68. Read More

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Clinically Relevant Activity of the Novel RASP Inhibitor Reproxalap in Allergic Conjunctivitis: The Phase 3 ALLEVIATE Trial.

Am J Ophthalmol 2021 May 1. Epub 2021 May 1.

Aldeyra Therapeutics, Lexington, MA. Electronic address:

Purpose: To assess the post-acute activity and clinical utility of reproxalap, a novel reactive aldehyde species (RASP) inhibitor, versus vehicle in patients with seasonal allergic conjunctivitis.

Design: Parallel-group, double-masked, randomized Phase 3 trial.

Methods: Two topical ocular reproxalap concentrations (0. Read More

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Diclofenac Versus Dexamethasone Following Strabismus Surgery: A Systematic Review and Meta-Analysis.

J Ocul Pharmacol Ther 2021 Apr 30. Epub 2021 Apr 30.

Department of Pediatric Surgery, King Abdullah Specialist Children's Hospital, Ministry of National Guards, Riyadh, Saudi Arabia.

To compare outcomes of diclofenac versus dexamethasone in patients after strabismus surgery. A systematic review and meta-analysis were performed as per the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A search was conducted on MEDLINE, EMBASE, EMCARE, CINAHL, and the Cochrane Central Register of Controlled Trials (CENTRAL). Read More

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Short-Term Outcomes of Pediatric Keratoprosthesis With the Near-Complete Conjunctival Flap.

Cornea 2021 Jun;40(6):679-684

Flaum Eye Institute, University of Rochester Medical Center, Rochester, NY.

Purpose: The Boston keratoprosthesis (KPro) has been used for certain indications in pediatric patients with congenital corneal opacities. Here, we describe the use of a near-complete conjunctival flap at the time of Boston type 1 KPro surgery in pediatric patients, with the goal of improving pediatric KPro outcomes.

Methods: We performed a retrospective chart review of 21 eyes from 16 patients who received their first KPro before the age of 18 years at a tertiary care center in Rochester, NY. Read More

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Oxidative and antioxidative stress markers in dry eye disease: A systematic review and meta-analysis.

Acta Ophthalmol 2021 May 2. Epub 2021 May 2.

Université Clermont Auvergne, CNRS, LaPSCo, Physiological and Psychosocial Stress, CHU Clermont-Ferrand, University Hospital of Clermont-Ferrand, Preventive and Occupational Medicine, Witty Fit, Clermont-Ferrand, France.

Purpose: To conduct a systematic review and meta-analysis on the levels of oxidative stress markers and antioxidants in dry eye disease (DED) compared with healthy subject.

Method: The PubMed, Cochrane Library, Embase, Science Direct and Google Scholar databases were searched on 10 January 2021 for studies reporting oxidative and antioxidative stress markers in DED and healthy controls. Main meta-analysis was stratified by type of biomarkers, type of samples (tears, conjunctival cells or biopsies), Sjögren's syndrome (SS) (patients with or without SS) and by geographical zones (Asia or Europe). Read More

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Analysis of the Conjunctival Microbiome in Patients with Atopic Keratoconjunctivitis and Healthy Individuals.

Ann Dermatol 2021 Apr 8;33(2):163-169. Epub 2021 Mar 8.

Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.

Background: Atopic dermatitis (AD) has been clarified that imbalance of bacterial and fungal communities in the skin and gut play key roles in immunologic dysfunction. Atopic keratoconjunctivitis (AKC), one of severe ophthalmic manifestation of AD, could be related with dysbiosis as same as AD.

Objective: In this case-control study, the roles of conjunctival microbial communities in AKC were evaluated by a comparative analysis with healthy controls (HCs). Read More

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