189,777 results match your criteria concern ivcm

Inverse probability weighting is an effective method to address selection bias during the analysis of high dimensional data.

Genet Epidemiol 2021 Jun 15. Epub 2021 Jun 15.

Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, Colorado, USA.

Omics studies frequently use samples collected during cohort studies. Conditioning on sample availability can cause selection bias if sample availability is nonrandom. Inverse probability weighting (IPW) is purported to reduce this bias. Read More

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Microplastic degradation methods and corresponding degradation mechanism: Research status and future perspectives.

J Hazard Mater 2021 Jun 10;418:126377. Epub 2021 Jun 10.

Joint Laboratory of Guangdong Province and Hong Kong Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural University, Guangzhou 510642, China; Institute of Eco-Environmental Research, Guangxi Academy of Sciences, Nanning 530007, China. Electronic address:

Microplastics (MPs) pollution has become a global environmental concern because of their severe threat to biota. However, limited studies on the elimination of MPs pollution were reported. The conventional treatment methods were not suitable for MPs owing to their smaller size than plastic items. Read More

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Promoting cross-regional collaboration in antimicrobial stewardship: Findings of an infectious diseases working group survey in Arab countries of the Middle East.

J Infect Public Health 2021 Apr 24;14(7):978-984. Epub 2021 Apr 24.

American University of Beirut Medical Center, Beirut, Lebanon. Electronic address:

Background: Antimicrobial resistance is a significant global issue that presents an increasing threat to patients' wellbeing. Although a global concern, the emergence of multi-drug resistant organisms is of particular significance in the Middle East. In recent years, this region has seen an alarming increase in antimicrobial resistance presenting a major challenge to physicians managing various infectious diseases. Read More

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Effect of plastic film mulching and film residues on phthalate esters concentrations in soil and plants, and its risk assessment.

Environ Pollut 2021 Jun 9;286:117546. Epub 2021 Jun 9.

State Key Laboratory of Grassland Agroecosystems, Institute of Arid Agroecology, School of Life Sciences, Lanzhou University, Lanzhou, Gansu Province, 730000, China. Electronic address:

The application of plastic film mulching can greatly improve dryland productivity, while the release of toxic phthalate esters (PAEs) from the plastic film has generated concern. This study investigated the effects of mulched plastic film and residual plastic film on the PAE concentrations in the soil-crop system and assessed the risks to people eating crop products. The PAEs concentration in the 0-25 cm soil layer of plastic mulched farmland was 0. Read More

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In vivo evaluation of deer antler trabecular bone as a reconstruction material for bone defects.

Res Vet Sci 2021 Jun 11;138:116-124. Epub 2021 Jun 11.

Department of Clinical Sciences, FARAH, Faculty of Veterinary Medicine, University of Liège, Quartier Vallée 2, Avenue de Cureghem 1 - B67, Liège, Belgium.

Availability of graft materials to fill up osseous defects has always been a concern in orthopaedic surgeries. Deer antler material is a primary bone structure that is easy to collect and could serve as a xenograft. This study examines the behaviour of red deer antler trabecular cylinders in critical size distal femoral epiphyseal defects in 11 rabbits, and evaluates the effect of the decellularization protocols. Read More

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Degradation of amoxicillin with sono, photo, and sonophotocatalytic oxidation under low-frequency ultrasound and visible light.

Environ Res 2021 Jun 12;200:111515. Epub 2021 Jun 12.

Environmental Science and Engineering Department, Indian Institute of Technology Bombay, Mumbai, 400 076, India. Electronic address:

The presence of pharmaceutically active compounds in aquatic bodies is a global concern, and suitable treatment technologies are required. In this study, the efficacy of photocatalytic, sonocatalytic, and sonophotocatalytic oxidation processes for the degradation of amoxicillin (AMX) was investigated using visible light with N doped TiO (N-TiO) nanoparticles as the catalyst and low-frequency ultrasound in a novel multifrequency reactor. The influence of different operational parameters on the extent of AMX degradation was studied. Read More

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Fracture risk during extraction of well-fixed extended cementless stems : porous versus hydroxyapatite coated.

Acta Orthop Belg 2021 Mar;87(1):41-45

The concern of extensive fracturing and bone damage during implant removal has been reported for ingrowing stems, in particular in extended porous coated stems, potentially impeding successful re- implantation of a femoral revision implant and consequently debilitating patients for life. The aim of the present study is to describe this particular complication and comparing the occurrence in porous coated and hydroxyapatite (HA) coated femoral implants. 62 consecutive revision hip replacements were per- formed between January 2010 and December 2016 at a single academic institution. Read More

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Dual mobility versus unipolar total hip arthroplasty for neck of femur fractures : a single centre study.

Acta Orthop Belg 2021 Mar;87(1):35-39

Current national guidelines (NICE) recommends that all medically fit, independently-mobile patients without cognitive impairment receive a total hip arTHAoplasty(THA) for displaced intracapsular neck of femur (NOF) fractures. Dislocation is a concern(2-10%). Dual mobility cups have been suggested to address this complication. Read More

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Disability, pain, and wound-specific concerns self-reported by adults at risk of limb loss: A cross-sectional study using the World Health Organization Disability Assessment Schedule 2.0.

PLoS One 2021 15;16(6):e0253288. Epub 2021 Jun 15.

Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

Introduction: There has been limited study of patient-reported outcomes (PROs) in patients at risk of limb loss. Our primary objective was to estimate the prevalence of disability in this patient population using the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2. Read More

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Azole resistance in species: Promising therapeutic options.

Expert Opin Pharmacother 2021 Jun 15. Epub 2021 Jun 15.

Division of Infectious Diseases, Wayne State University School of Medicine, Detroit, MI.

Introduction: Azoles are the first line antifungal agents used for the treatment of infection. There is increasing concern for azole resistance all over the world mainly from agricultural fungicide use. Choosing safe and effective antifungal regimens has become a challenge. Read More

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Effect of Virtual Reality Perspective-Taking on Related and Unrelated Contexts.

Cyberpsychol Behav Soc Netw 2021 Jun 14. Epub 2021 Jun 14.

Department of Communication, Stanford University, Stanford, California, USA.

Virtual reality perspective-taking (VRPT) experiences effectively increase both empathy and prosocial behaviors toward related social targets (e.g., cutting down a tree in virtual reality increases concern for the environment). Read More

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Metallo-β-lactamases in the Age of Multidrug Resistance: From Structure and Mechanism to Evolution, Dissemination, and Inhibitor Design.

Chem Rev 2021 Jun 15. Epub 2021 Jun 15.

Instituto de Biología Molecular y Celular de Rosario (IBR), CONICET, Universidad Nacional de Rosario, Ocampo y Esmeralda S/N, 2000 Rosario, Argentina.

Antimicrobial resistance is one of the major problems in current practical medicine. The spread of genes coding for resistance determinants among bacteria challenges the use of approved antibiotics, narrowing the options for treatment. Resistance to carbapenems, last resort antibiotics, is a major concern. Read More

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Heading in Football: Incidence, Biomechanical Characteristics and the Association with Acute Cognitive Function-A Three-Part Systematic Review.

Sports Med 2021 Jun 15. Epub 2021 Jun 15.

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.

Background: There is growing concern surrounding the role of repetitive sub-concussive head impacts, such as football heading, on brain health.

Objectives: Three questions were addressed while only considering studies that observed heading exposure directly: (1) how frequently does heading occur within football training and matches, (2) what are the biomechanical characteristics of heading, and (3) is cognitive function affected by heading?

Methods: This review followed the steps described in the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines. Electronic databases including MEDLINE and SPORTDiscus were searched from the earliest entry to July 2020. Read More

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Risk assessment of heavy metals in marine fish and seafood from Kedah and Selangor coastal regions of Malaysia: a high-risk health concern for consumers.

Environ Sci Pollut Res Int 2021 Jun 15. Epub 2021 Jun 15.

School of Chemical Engineering, The University of New South Wales, Sydney, Australia.

The heavy metals namely Fe, As, Cu, Cd, and Pb were investigated in two marine fishes silver pomfret (Pampus argentus) and torpedo scad (Megalaspis cordyla), and three seafoods sibogae squid (Loligo sibogae), Indian white prawn (Fenneropenaeus indicus), and mud crab (Scylla serrata) by using inductively coupled plasma spectrophotometer (ICP-MS) from two renowned fish harvesting coastal area of Malaysia named as Kedah and Selangor. Among the target heavy metals, highest mean concentration of As and Fe were found in Scylla serrata (72.14±7. Read More

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Decline of parasitic and habitat-specialist species drives taxonomic, phylogenetic and functional homogenization of sub-alpine bumblebee communities.

Oecologia 2021 Jun 15. Epub 2021 Jun 15.

Department of Ecology, Swedish University of Agricultural Sciences, Box 7044, 75007, Uppsala, Sweden.

The ongoing biodiversity crisis is characterised not only by an elevated extinction rate but also can lead to an increasing similarity of species assemblages. This is an issue of major concern, as it can reduce ecosystem resilience and functionality. Changes in the composition of pollinator communities have mainly been described in intensive agricultural lowland areas. Read More

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Rapid Increase of SARS-CoV-2 Variant B.1.1.7 Detected in Sewage Samples from England between October 2020 and January 2021.

mSystems 2021 Jun 15:e0035321. Epub 2021 Jun 15.

Division of Virology, National Institute for Biological Standards and Control, South Mimms, Potters Bar, Hertfordshire, UK.

SARS-CoV-2 variants with multiple amino acid mutations in the spike protein are emerging in different parts of the world, raising concerns regarding their possible impact on human immune response and vaccine efficacy against the virus. Recently, a variant named lineage B.1. Read More

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Integrative Medicine: Manual Therapy.

FP Essent 2021 Jun;505:11-17

F. Edward Hébert School of Medicine at the Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814.

Manual therapy, or manipulative therapy, is performed primarily by osteopathic physicians, chiropractors, and physical therapists to relieve pain and improve function. As safe prescribing of opioids has become a concern and nondrug therapies for pain management are used more widely, manual therapy has become an attractive treatment option for many patients. A variety of techniques are used, including myofascial release, strain-counterstrain, muscle energy, high velocity/low amplitude, Still, and others. Read More

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Secondary Traumatic Stress in Emergency Services Systems (STRESS) Project: Quantifying and Predicting Compassion Fatigue in Emergency Medical Services Personnel.

Prehosp Emerg Care 2021 Jun 15:1-16. Epub 2021 Jun 15.

Department of Emergency Medical Science, Wake Technical Community College, Raleigh, North Carolina.

Compassion fatigue (CF) is defined as the acute or gradual loss of benevolence that occurs after exposure to critical incident stress. Colloquially referred to as the "cost of caring," CF can affect an individual's future response to stressful situations and is unhealthy for caregivers.To identify the prevalence and predictors of CF in EMS professionals. Read More

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Pediatric oncology clinician communication about sexual health with adolescents and young adults: A report from the children's oncology group.

Cancer Med 2021 Jun 15. Epub 2021 Jun 15.

Cancer and Blood Disease Institute, Children's Hospital Los Angeles, USC Norris Comprehensive Cancer Center, Los Angeles, CA, USA.

Background: Sexual health (SH) is an important concern for adolescents and young adults (AYAs). This study determined current SH communication practices, barriers, and additional resources needed among pediatric oncology clinicians who treat AYAs.

Methods: A cross-sectional survey was developed by the Children's Oncology Group (COG) AYA Committee and sent to pediatric oncologists (n = 1,987; 85. Read More

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Debate: Is there a true global children and young people's mental health crisis, fact or fiction?

Child Adolesc Ment Health 2021 Jun 15. Epub 2021 Jun 15.

Department of Psychiatry, University of Cambridge, Cambridge, UK.

Following COVID-19, there has been increasing concern about the well-being of children and young people across the United Kingdom; however, our major problem is the lack of robust data. We discuss emerging research capturing the impact of restrictions and experiences of COVID-19 on children and young people. We suggest further and more detailed analysis is urgently required to inform an evidence-based response. Read More

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The concentration of potentially toxic elements (PTEs) in sausages: a systematic review and meta-analysis study.

Environ Sci Pollut Res Int 2021 Jun 15. Epub 2021 Jun 15.

Department of Food Science and Nutrition, University of Campinas (UNICAMP), Rua Monteiro Lobato, 80 Caixa Postal: 6121 CEP, São Paulo, 13083-862, Campinas, Brazil.

The contamination of fresh meat and meat products like sausages with potentially toxic elements (PTEs) is a worldwide health concern. Consequently, the related investigations concerning the levels of PTEs in sausages among databases such as Scopus, Cochrane, and PubMed were investigated 1 January 2000 to 20 August 2020. Furthermore, the concentration of PTEs in sausages was meta-analyzed based on the random effect model (REM). Read More

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Toxic element profile of ice cream in Bangladesh: a health risk assessment study.

Environ Monit Assess 2021 Jun 14;193(7):421. Epub 2021 Jun 14.

Chemistry Discipline, Khulna University, Khulna 9208, Bangladesh.

Ice cream is a popular frozen dairy product and a possible source of dietary minerals. However, ice cream may also contain toxic metals, which may cause several health implications. The current study aimed to determine the content of toxic elements in ice cream samples using inductively coupled plasma-optical emission spectrometry (ICP-OES) and to assess the health risks of consumers based on target cancer risk (TCR), target hazard quotient (THQ), and hazardous index (HI). Read More

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Elite professional goalkeepers report high rate of sport resumption after shoulder surgery.

Knee Surg Sports Traumatol Arthrosc 2021 Jun 15. Epub 2021 Jun 15.

Shoulder and Elbow Unit, Department of Orthopedic and Trauma Surgery, Humanitas Clinical and Research Center, IRCCS, via Manzoni 56, Rozzano, 20089, Milan, Italy.

Purpose: The aim of this study is to evaluate the return to sport after surgical treatment of shoulder injuries in professional goalkeepers in relationship with the mechanism of injury and the pattern of related shoulder lesions.

Methods: Twenty-six shoulders in nineteen elite male professional soccer goalkeepers were retrospectively analyzed considering multiple diseases (instability, rotator cuff, biceps or other tendon injuries). Data was collected for injury modality and context, pathological findings, surgical procedures, time, level of return to sport, and complications. Read More

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Mapping Potential Antigenic Drift Sites (PADS) on SARS-CoV-2 Spike in Continuous Epitope-Paratope Space.

bioRxiv 2021 Jun 8. Epub 2021 Jun 8.

SARS-CoV-2 mutations with antigenic effects pose a risk to immunity developed through vaccination and natural infection. While vaccine updates for current variants of concern (VOCs) are underway, it is likewise important to prepare for further antigenic mutations as the virus navigates the heterogeneous global landscape of host immunity. Toward this end, a wealth of data and tools exist that can augment existing genetic surveillance of VOC evolution. Read More

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Diabetic ketoacidosis at presentation of type 1 diabetes in children in Canada during the COVID-19 pandemic.

Paediatr Child Health 2021 Jul 8;26(4):208-209. Epub 2021 Apr 8.

Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada.

Type 1 diabetes is a common chronic illness in childhood. Diabetic ketoacidosis (DKA) is the leading cause of morbidity and mortality in children with type 1 diabetes. Early recognition of symptoms of diabetes and immediate initiation of treatment are important factors in preventing DKA at first presentation. Read More

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Evidence for increased breakthrough rates of SARS-CoV-2 variants of concern in BNT162b2-mRNA-vaccinated individuals.

Nat Med 2021 Jun 14. Epub 2021 Jun 14.

The Shmunis School of Biomedicine and Cancer Research, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.

The BNT162b2 mRNA vaccine is highly effective against SARS-CoV-2. However, apprehension exists that variants of concern (VOCs) may evade vaccine protection, due to evidence of reduced neutralization of the VOCs B.1. Read More

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A Case of Rapid Transformation from Hydatidiform Mole to Invasive Mole: The Importance of β-hCG (Human Chorionic Gonadotropin) Serum Levels in Follow-Up Evaluation.

Am J Case Rep 2021 Jun 15;22:e931156. Epub 2021 Jun 15.

Division of Pharmacology and Therapy, Department of Anatomy, Histology, and Pharmacology, Faculty of Medicine Universitas Airlangga, Surabaya, Indonesia.

BACKGROUND Gestational trophoblastic disease (GTD) is a spectrum of disorders consisting of premalignant (ie, complete [CHM] and partial hydatidiform moles [PHM]) and malignant conditions (ie, invasive moles, choriocarcinoma, placental site trophoblastic tumors, and epithelioid trophoblastic tumor). If GTD persists after initial treatment and has persistent elevated beta human chorionic gonadotropin (ß-hCG), it is referred to as post-molar gestational trophoblastic neoplasia (pGTN). To date, there is no detailed information regarding how fast invasive moles can develop from CHM. Read More

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Monoclonal B lymphocytosis in a kidney transplant recipient.

BMJ Case Rep 2021 Jun 14;14(6). Epub 2021 Jun 14.

Department of Surgical, Medical, Dental and Morphological Sciences, Università degli Studi di Modena e Reggio Emilia, Modena, Emilia-Romagna, Italy.

Monoclonal B lymphocytosis (MBL) is a lymphoproliferative condition characterised by expansion of a B-cell clone in peripheral blood, with an often indolent clinical course. The presence of a B clonal population alone is several hundred times more common in the general population than chronic lymphocytic leukaemia and other non-Hodgkin's lymphoma subtypes, it usually does not represent a malignant condition and it requires follow-up only, without specific treatment. There are few studies describing MBL in solid organ transplant recipients, thus, the concern is raised when enrolling MBL affected subjects in waiting lists. Read More

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