Indian J Microbiol 2021 Jun 22;61(2):195-202. Epub 2021 Mar 22.
Institute of Molecular Medicine, College of Life Science, Zhejiang Chinese Medical University, Hangzhou, 310053 Zhejiang People's Republic of China.
Biphenanthrene compound, 4, 8, 4', 8'-tetramethoxy (1, 1'-biphenanthrene)-2, 7, 2', 7'-tetrol (LF05), recently isolated from fibrous roots of , exhibits antibacterial activity against several Gram-positive bacteria. In this study, we investigated the antibacterial properties, potential mode of action and cytotoxicity. Minimum inhibitory concentrations (MICs) tests showed LF05 was active against all tested Gram-positive strains, including methicillin-resistant (MRSA) and staphylococcal clinical isolates. Read More