174,819 results match your criteria composite

Linking Neutrophil Extracellular Traps and Platelet Activation: A Composite Biomarker Score for Predicting Outcomes after Acute Myocardial Infarction.

Thromb Haemost 2021 May 13. Epub 2021 May 13.

Department of Surgery and Anaesthesia, The University of Otago, Wellington, New Zealand.

Background:  Activation of both platelets and neutrophils can contribute to the risk of major adverse cardiovascular events (MACE) following acute myocardial infarction (AMI). Neutrophil extracellular traps (NETs) are an important product of the platelet-neutrophil axis and exaggerate vascular damage in cardiovascular disease. Additionally, activated platelets can drive NETosis and are directly linked to thromboembolic risk. Read More

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Trout-like multifunctional piezoelectric robotic fish and energy harvester.

Bioinspir Biomim 2021 May 13. Epub 2021 May 13.

Mechanical Engineering, Georgia Institute of Technology, 771 Ferst Dr NW, Atlanta, Georgia, 30332, UNITED STATES.

This work presents our experimental studies on a trout-inspired multifunctional robotic fish as an underwater swimmer and energy harvester. Fiber-based flexible piezoelectric composites with interdigitated electrodes, specifically Macro-Fiber Composite (MFC) structures, strike a balance between the deformation and actuation force capabilities to generate hydrodynamic propulsion without requiring additional mechanisms for motion amplification. A pair of MFC laminates bracketing a passive fin functions like artificial muscle when driven out of phase to expand and contract on each side to create bending. Read More

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A highly durable CoOx/N-doped Graphitized- Nano-Diamond electrocatalyst for oxygen reduction reaction.

Nanotechnology 2021 May 13. Epub 2021 May 13.

Henan Functional Diamond Material Innovation Center, Zhengzhou, CHINA.

Oxygen reduction reaction (ORR) occupies a pivotal position in fuel cell applications, and it is a challenge to obtain highly durable ORR catalysts. Herein, porous cobalt oxide microsphere growing at the surface of on nitrogen-doped graphitized-nano-diamond (CoOx/N-GND) was prepared using hydrothermal and subsequent heat treatment process. Porous cobalt oxide of high specific surface area could expose more surface Co2+ that act as active sites than bulk one does. Read More

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Robust hetero-MoO/MoO@N-doped carbon nanobelts decorated with oxygen deficiencies as high-performance anodes for potassium/sodium storage.

J Colloid Interface Sci 2021 Apr 24;599:730-740. Epub 2021 Apr 24.

School of Chemical and Biomolecular Engineering, The University of Sydney, Australia. Electronic address:

Hetero-MoO/MoO@N-doped carbon nanobelt anodes (h-MoO/MoO@NC) with long lifespan and superior rate capability were proposed by a simple in situ reduction tactic, in which pristine MoO was transformed into heterogeneous MoO/MoO. The hetero-MoO/MoO architecture significantly improves the electronic conductivity and affords abundant oxygen deficiencies. Meanwhile, the synergistic effect of internal MoO/MoO heterostructure and outer N-doped carbon layer (NC) accomplishes a balance of sustainable potassium/sodium storage and ultra-durable structure stability. Read More

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AgI/CuWO Z-scheme photocatalyst for the degradation of organic pollutants: Experimental and molecular dynamics studies.

J Colloid Interface Sci 2021 Apr 28;599:717-729. Epub 2021 Apr 28.

Department of Chemistry, Indian Institute of Technology (Banaras Hindu University), Varanasi 221005, India. Electronic address:

While the knowledge of the adsorption properties of components of a composite heterogeneous photocatalyst is critical to its applicability to a particular reaction, there has been little research in this direction. The present research is on the development of AgI/CuWO nanocomposites that photocatalytically degraded ciprofloxacin and rhodamine B in an aqueous medium under visible light irradiation. The nanocomposites were prepared by a step-wise precipitation protocol. Read More

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A novel tool for the adsorption of dsDNA: Electrochemical reduction of Pd nanoparticles onto reduced-keratin particles extracted from wool wastes.

Bioelectrochemistry 2021 May 5;140:107835. Epub 2021 May 5.

Ankara University, Faculty of Science, Department of Chemistry, Ankara, Turkey. Electronic address:

This work outlines the fabrication of a novel electrochemical platform for the dsDNA adsorption, using one of the most sustainable materials, wool fabric waste, and Pd ions. To develop a functional material with a significant adsorption capability, the waste wool was subjected to the chemical reduction process, and the keratin-SH (KerSH) particles were extracted in powder form. These particles were used in the adsorption of Pd ions by monitoring with the UV-vis spectra. Read More

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The regulating effect of trace elements Si, Zn and Sr on mineralization of gelatin-hydroxyapatite electrospun fiber.

Colloids Surf B Biointerfaces 2021 May 10;204:111822. Epub 2021 May 10.

National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, PR China. Electronic address:

Biomineralization approaches have been increasingly adopted to synthesizing advanced materials with superior properties. Nevertheless, the potential influence of inorganic trace elements on the mineralization process of collagen has been rarely reported, despite of the significant progress achieved on exploiting the critical roles of organic polymers in regulating the collagen mineralization. To this aim, the potential roles of Si, Zn and Sr in regulating the mineralization of gelatin-hydroxyapatite (HA) composite fibers have been examined in this study. Read More

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Delivery of curcumin using a zein-xanthan gum nanocomplex: Fabrication, characterization, and in vitro release properties.

Colloids Surf B Biointerfaces 2021 May 10;204:111827. Epub 2021 May 10.

School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan, 316022, PR China. Electronic address:

This study aimed to use xanthan gum as a stabilizer to improve the stability of zein nanoparticles. Zein-xanthan gum composite nanoparticles were prepared via anti-solvent precipitation at pH 4.0. Read More

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Fabrication of bioactive binary composite film based on gelatin/chitosan incorporated with cinnamon essential oil and rutin.

Colloids Surf B Biointerfaces 2021 May 6;204:111830. Epub 2021 May 6.

Department of Food and Nutrition, BioNanocomposite Research Center, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, Republic of Korea. Electronic address:

Chitosan/gelatin-based functional films were fabricated by incorporating cinnamon essential oil (CEO) and rutin for active packaging application. The functional fillers were evenly distributed in the polymer matrix and formed a film compatible with the chitosan/gelatin polymer matrix. However, the functional material did not affect the physical properties such as mechanical, thermal, and water vapor barrier properties of the film but exhibited high light transmittance with enhanced UV blocking properties. Read More

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MXene@Ag-based ratiometric electrochemical sensing strategy for effective detection of carbendazim in vegetable samples.

Food Chem 2021 May 4;360:130006. Epub 2021 May 4.

Key Laboratory of Crop Physiology, Ecology and Genetic Breeding, Ministry of Education, Key Laboratory of Chemical Utilization of Plant Resources of Nanchang, College of Science, Jiangxi Agricultural University, Nanchang 330045, PR China. Electronic address:

In this paper, a novel ratiometric electrochemical sensor for carbendazim (CBZ) detection was constructed by a composite of MXene@Ag nanoclusters and amino-functionalized multi-walled carbon nanotubes (MXene@AgNCs/NH-MWCNTs). The Ag nanoclusters (AgNCs) embedded in the MXene not only could inhibit the aggregation of MXene flakes and enhance the electrocatalytic ability, but also serve as an internal reference probe for the ratiometric electrochemical detection. Moreover, the introduction of NH-MWCNTs can further improve the electrochemical signals of CBZ and Ag, resulting in the enhanced signal amplification and higher sensitivity. Read More

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Comparison of baroreflex sensitivity indices with standard tests of autonomic nervous system function.

J Neurol Sci 2021 Apr 30;426:117473. Epub 2021 Apr 30.

School of Medicine, University of Zagreb, Zagreb, Croatia; University Hospital Center Zagreb, Department of Neurology, Referral Center for Autonomic Nervous System Disorders, Zagreb, Croatia. Electronic address:

Objective: In order to further evaluate clinical usefulness of α- and β-adrenergic components of the baroreflex sensitivity (BRS) index, the aim of this study was to compare them to standardized measures of the autonomic dysfunction.

Methods: In 275 participants (mean age 40.57 ± 15. Read More

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The impact of peak and duration of maternal intrapartum fever on perinatal outcomes.

Am J Obstet Gynecol MFM 2021 May 10:100390. Epub 2021 May 10.

Department of Obstetrics and Gynecology, Hadassah Hebrew University Medical Center, Mount-Scopus, Jerusalem, Israel.

Objective: Intrapartum fever is a common perinatal complication, associated with short and long term adverse outcomes. Sparse data exists regarding the association between the peak and duration of maternal fever and the extent and severity of maternal and neonatal complications. This study aims to examine the association between maternal intrapartum fever peak and duration, and perinatal outcomes. Read More

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Metrics to evaluate the performance of auto-segmentation for radiation treatment planning: a critical review.

Radiother Oncol 2021 May 10. Epub 2021 May 10.

Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address:

Advances in artificial intelligence-based methods have led to the development and publication of numerous systems for auto-segmentation in radiotherapy. These systems have the potential to decrease contouring variability, which has been associated with poor clinical outcomes, and increase efficiency in the treatment planning workflow. However, there are no uniform standards for evaluating auto-segmentation platforms to assess their efficacy at meeting these goals. Read More

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Days Alive Out of Hospital in Heart Failure: Insights from the PARADIGM-HF and CHARM Trials.

Am Heart J 2021 May 10. Epub 2021 May 10.

Director, Division of Cardiology and Nephrology, Center for Drug Evaluation and Research, U.S. Food and Drug Administration.

Background: An endpoint that has received some attention in recent cardiovascular trials is 'days alive and out of hospital' (DAOH). Percent DAOH is a natural extension of DAOH that adjusts for differences in length of follow-up. This endpoint measure incorporates mortality and morbidity together in a way that has the potential to give more insight regarding treatment effects compared to conventional time-to-event endpoints. Read More

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Superamphiphilic TiO Composite Surface for Protein Antifouling.

Adv Mater 2021 May 13:e2003559. Epub 2021 May 13.

CAS Key Laboratory of Bio-Inspired Materials and Interface Sciences, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.

Unwanted protein adsorption deteriorates fouling processes and reduces analytical device performance. Wettability plays an important role in protein adsorption by affecting interactions between proteins and surfaces. However, the principles of protein adsorption are not completely understood, and surface coatings that exhibit resistance to protein adsorption and long-term stability still need to be developed. Read More

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Golden Vaterite as a Mesoscopic Metamaterial for Biophotonic Applications.

Adv Mater 2021 May 13:e2008484. Epub 2021 May 13.

Department of Electrical Engineering, Tel Aviv University, Ramat Aviv, Tel Aviv, 69978, Israel.

Mesoscopic photonic systems with tailored optical responses have great potential to open new frontiers in implantable biomedical devices. However, biocompatibility is typically a problem, as engineering of optical properties often calls for using toxic compounds and chemicals, unsuitable for in vivo applications. Here, a unique approach to biofriendly delivery of optical resonances is demonstrated. Read More

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A novel Vancomycin-Functionalized-Magnetic Graphene Composite for Use as a Near-Infrared-Induced Synergistic Chemo-Photothermal Antibacterial.

Macromol Biosci 2021 May 13:e2100082. Epub 2021 May 13.

Laboratory of Nanoscale Biosensing and Bioimaging (NBAB), School of Ophthalmology and Optometry, School of Biomedical Engineering, State Key Laboratory of Ophthalmology, Optometry, and Vision Science, Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.

Antibiotic-resistant bacterial strains are a major cause of disease. They continue to remain a challenge in the clinic particularly in the vision system. For example, infectious endophthalmitis is a major blind-causing disease caused by bacteria. Read More

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Hierarchical semantic composition of biosimulation models using bond graphs.

PLoS Comput Biol 2021 May 13;17(5):e1008859. Epub 2021 May 13.

Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand.

Simulating complex biological and physiological systems and predicting their behaviours under different conditions remains challenging. Breaking systems into smaller and more manageable modules can address this challenge, assisting both model development and simulation. Nevertheless, existing computational models in biology and physiology are often not modular and therefore difficult to assemble into larger models. Read More

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Surveillance of Vaccination Coverage Among Adult Populations -United States, 2018.

MMWR Surveill Summ 2021 May 14;70(3):1-26. Epub 2021 May 14.

Problem/condition: Adults are at risk for illness, hospitalization, disability and, in some cases, death from vaccine-preventable diseases, particularly influenza and pneumococcal disease. CDC recommends vaccinations for adults on the basis of age, health conditions, prior vaccinations, and other considerations. Updated vaccination recommendations from CDC are published annually in the U. Read More

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Directional PCA for Fast Detection and Accurate Diagnosis: A Unified Framework.

IEEE Trans Cybern 2021 May 13;PP. Epub 2021 May 13.

Many methods for monitoring multivariate processes are built on principal component analysis (PCA), which, however, simply tells whether the process is faulty or not. In fact, there is still room for the improvement of the early detection performance by exploiting fully the information given by fault directions. To this end, this article proposes a novel directional PCA (diPCA) approach. Read More

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Confirmatory factor analysis of imPACT cognitive tests in high school athletes.

Psychol Assess 2021 May 13. Epub 2021 May 13.

Department of Psychology, University of Nevada, Las Vegas.

ImPACT is the most commonly utilized computerized neurocognitive assessment for the clinical management of sport concussion. The cognitive composite scores that ImPACT currently reports include Verbal Memory, Visual Memory, Visual Motor Speed, Reaction Time, and Impulse Control. However, exploratory factor analytic studies report that two or more factors may better represent ImPACT's latent structure, suggesting that the current cognitive composites may not adequately represent the cognitive constructs ImPACT assesses. Read More

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Validation of The Edinburgh Cognitive and Behavioural ALS Screen (ECAS) in behavioural variant Frontotemporal Dementia and Alzheimer's Disease.

Int J Geriatr Psychiatry 2021 May 13. Epub 2021 May 13.

Human Cognitive Neuroscience -Psychology, School of Philosophy, Psychology and Language Sciences, University of Edinburgh.

The Edinburgh Cognitive and Behavioural ALS Screen (ECAS) was developed to assess cognitive and behavioural changes in an anterior frontotemporal syndrome (executive functions, language, fluency and behaviour), common in Amyotrophic Lateral Sclerosis (ALS) and also assesses posterior cerebral dysfunction (memory and visuospatial abilities).

Objectives: To validate the ECAS in behavioural variant Frontotemporal Dementia (bvFTD) without ALS, as compared with Alzheimer's Disease (AD), against comprehensive neuropsychological assessment. Compare its sensitivity to that of the Addenbrooke's Cognitive Examination (ACE-III) and investigate behavioural changes in both types of dementia. Read More

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Echocardiographic parameters associated with in-hospital adverse outcomes in patients with Takotsubo syndrome.

Echocardiography 2021 May 13. Epub 2021 May 13.

Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Introduction: Takotsubo syndrome (TTS) is an acute heart failure syndrome that leads to significant morbidity and mortality. We sought to evaluate the association of cardiac mechanics on presentation with in-hospital adverse outcomes in patients with apical TTS.

Methods: We retrospectively identified 468 patients with TTS based on ICD-9/10 codes between 2006 and 2017. Read More

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Preparation of GO/MIL-101(Fe,Cu) composite and its adsorption mechanisms for phosphate in aqueous solution.

Environ Sci Pollut Res Int 2021 May 13. Epub 2021 May 13.

College of Geology and Environment, Xi'an University of science and technology, Xi'an, 710054, People's Republic of China.

In this study, MIL-101(Fe), MIL-101(Fe,Cu), and graphene oxide (GO)/MIL-101(Fe,Cu) were synthesized to compose a novel sorbent. The adsorption properties of these three MOF-based composites were compared toward the removal of phosphate. Furthermore, the influencing factors including adsorption time, pH, temperature, and initial concentration on the adsorption capacity of phosphate on these materials as well as the reusability of the material were discussed. Read More

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Comparison of the Quality of Chronic Disease Management Between Adults With and Without Dementia.

JAMA Netw Open 2021 May 3;4(5):e219622. Epub 2021 May 3.

Department of Health Policy and Management, UCLA (University of California, Los Angeles), Fielding School of Public Health.

Importance: Adults with dementia may experience poorer quality of chronic disease management because of the difficulty in reporting symptoms and engaging in shared decision-making associated with cognitive impairment.

Objective: To compare the quality of chronic disease management received by adults with and without dementia.

Design, Setting, And Participants: For this cross-sectional study, nationally representative data from noninstitutionalized patients 65 years or older were obtained from the 2002-2015 Medical Expenditure Panel Survey. Read More

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Comparative analyses of gibbon centromeres reveal dynamic genus specific shifts in repeat composition.

Mol Biol Evol 2021 May 13. Epub 2021 May 13.

Department of Medicine, Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR, 97239.

Centromeres are functionally conserved chromosomal loci essential for proper chromosome segregation during cell division, yet they show high sequence diversity across species. Despite their variation, a near universal feature of centromeres is the presence of repetitive sequences, such as DNA satellites and transposable elements (TEs). Because of their rapidly evolving karyotypes, gibbons represent a compelling model to investigate divergence of functional centromere sequences across short evolutionary timescales. Read More

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Three-zone multifocus hybrid Fresnel lens concentrator.

Appl Opt 2021 Apr;60(12):3281-3289

In this paper, we designed a three-zone multifocus hybrid Fresnel lens concentrator without a homogenizer. This concentrator uses three types of prisms: a refractive prism, a single total internal reflection (STIR) prism, and a double TIR (DTIR) prism. In order to achieve a uniform irradiance distribution, the Fresnel lens is cut into four quadrants and reconnected. Read More

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Design of a compact dual-channel panoramic annular lens with a large aperture and high resolution.

Appl Opt 2021 Apr;60(11):3094-3102

We propose a compact dual-channel panoramic annular lens (PAL) with a large aperture and high resolution to solve three major shortcomings of conventional PAL systems: resolution, imaging quality, and compactness. Using polarization technology, the system integrates two optical channels to eliminate the central blind area. Using our PAL aperture ray-tracing model, the large aperture PAL system with a low F-number of 2. Read More

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Soft Electronic Materials with Combinatorial Properties Generated Mussel-Inspired Chemistry and Halloysite Nanotube Reinforcement.

ACS Nano 2021 May 13. Epub 2021 May 13.

Department of Health Technology, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.

Soft and electrically active materials are currently being utilized for intelligent systems, including electronic skin, cybernetics, soft robotics, and wearable devices. However, fabricating materials that fulfill the complex requirements of such advanced applications remains a challenge. These attributes include electronic, adhesive, self-healing, flexible, moldable, printable, and strong mechanical properties. Read More

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Incidence of Acute Myeloid Leukemia and Myelodysplastic Syndrome in Patients With Inflammatory Bowel Disease and the Impact of Thiopurines on Their Risk.

Am J Gastroenterol 2021 Apr;116(4):741-747

1Department of Gastroenterology, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania, USA; 2Division of Gastroenterology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania, USA; 3Department of Internal Medicine, St. Mary Medical Center, Langhorne, Pennsylvania, USA; 4Center of Clinical Epidemiology and Biostatistics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania, USA; 5Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

Introduction: Acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) are rare myeloid clonal disorders that commonly affect the elderly population and have poor prognosis. There are limited data on the risk of AML/MDS among patients with inflammatory bowel disease (IBD), especially on the impact of thiopurines (TPs).

Methods: We conducted a retrospective cohort study among patients with IBD from Veteran Affairs data set. Read More

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