12,016 results match your criteria complications represented

Does lung cancer screening with low-dose computerized tomography improve survival?

Interact Cardiovasc Thorac Surg 2021 Jul 23. Epub 2021 Jul 23.

Department of Cardiothoracic Surgery, Westmead Hospital, Sydney, Australia.

A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was 'Does lung cancer screening with low-dose computerised tomography (LDCT) improve survival?' More than 963 papers were found, of which 8 randomized control trials and 1 meta-analysis represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers were tabulated. Read More

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[Same-day discharge after elective coronary angioplasty: a single-center initial experience].

G Ital Cardiol (Rome) 2021 Aug;22(8):665-669

U.O.C. Cardiologia.

Background: Percutaneous coronary intervention (PCI) is usually a procedure based on patient's hospitalization. However, the increasingly widespread use of radial access, the technical evolution of the devices employed and current pharmacotherapy standards have simplified this procedure with satisfying outcomes and significantly reduced complications. It can be assumed that overnight hospitalization may not impact patient safety. Read More

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Weight loss, hypertension and mental well-being improvements during COVID-19 with a multicomponent health promotion programme on Zoom: a service evaluation in primary care.

BMJ Nutr Prev Health 2021 15;4(1):102-110. Epub 2021 Feb 15.

Independent Researcher, London, UK.

Background: Obesity is a risk factor for complications from SARS-CoV-2 infection, increasing the need for effective weight management measures in primary care. However, in the UK, COVID-19 restrictions have hampered primary care weight management referral and delivery, and COVID-19 related weight gain has been reported. The present study evaluated outcomes from a multicomponent weight loss and health promotion programme in UK primary care, delivered remotely due to COVID-19 restrictions. Read More

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February 2021

Potential Impact of Diabetes and Obesity on Alveolar Type 2 (AT2)-Lipofibroblast (LIF) Interactions After COVID-19 Infection.

Front Cell Dev Biol 2021 8;9:676150. Epub 2021 Jul 8.

Faculty of Sciences and Advanced Technologies in Biology, University of Science and Culture, Tehran, Iran.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a new emerging respiratory virus, caused evolving pneumonia outbreak around the world. In SARS-Cov-2 infected patients, diabetes mellitus (DM) and obesity are two metabolic diseases associated with higher severity of SARS-CoV-2 related complications, characterized by acute lung injury requiring assisted ventilation as well as fibrosis development in surviving patients. Different factors are potentially responsible for this exacerbated response to SARS-CoV-2 infection. Read More

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ANCA-Associated Vasculitis Clinical Presentation and Clinical Predictors of Relapse in Saudi Arabia.

Open Access Rheumatol 2021 17;13:213-220. Epub 2021 Jul 17.

Rheumatology Unit, Department of Medicine, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

Background: Anti-neutrophil cytoplasm antibodies-associated vasculitis (AAV) is a rare autoimmune condition with high-relapsing rate and incidence of complications, resulting in increased morbidity and mortality. Characters of patients with anti-neutrophil cytoplasm antibodies-associated vasculitis in Saudi Arabia require further exploration.

Objective: To evaluate the clinical profile, relapse rate and disease-related complications among patients with AAV at a tertiary hospital in Saudi Arabia. Read More

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Soft-tissue reconstruction in lower-leg fracture-related infections: An orthoplastic outcome and risk factor analysis.

Injury 2021 Jul 16. Epub 2021 Jul 16.

Center for Musculoskeletal Infections, University Hospital Basel, Spitalstrasse 21, Basel CH-4031 Switzerland; Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital Basel, Switzerland.

Introduction Fracture-related infection (FRI) is a severe post-traumatic complication which is occasionally accompanied by a deficient or even avital soft-tissue envelope. In these cases, a thoroughly planned orthoplastic approach is imperative as a vital and intact soft-tissue envelope is mandatory to achieve fracture union and infection eradication. The aim of this study was, to analyse if soft-tissue reconstruction (STR) without complications is associated with a better long-term outcome compared to FRI patients with STR complications. Read More

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Endovascular treatment of a ruptured post-traumatic false aneurysm of the aortic isthmus: A case report.

Int J Surg Case Rep 2021 Jul 9;85:106190. Epub 2021 Jul 9.

Mohammed First University, Faculty of Medicine and Pharmacy, Oujda, Morocco; University Hospital Center Mohamed VI, Oujda, Morocco.

Introduction: The false aneurysm of the aortic isthmus is, given its severity and case fatality rate, a subject of interest in vascular surgery. The interest of this article is the analysis of the different characteristics of this pathology based on the study of a case report and on a review of the literature.

Case Report: This is a 21-year-old patient admitted for the management of a severe polytrauma following a fall from a cliff, causing him paraplegia following a fracture of the dorsal spine which is objectified on the CT bodyscan, which also shows the presence of a localized dissection with ruptured false aneurysm of the isthmus. Read More

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Coronary artery calcification on low-dose chest CT is an early predictor of severe progression of COVID-19-A multi-center, multi-vendor study.

PLoS One 2021 21;16(7):e0255045. Epub 2021 Jul 21.

Department of Radiology, University Hospital of Cologne, Cologne, Germany.

Purpose: Cardiovascular comorbidity anticipates severe progression of COVID-19 and becomes evident by coronary artery calcification (CAC) on low-dose chest computed tomography (LDCT). The purpose of this study was to predict a patient's obligation of intensive care treatment by evaluating the coronary calcium burden on the initial diagnostic LDCT.

Methods: Eighty-nine consecutive patients with parallel LDCT and positive RT-PCR for SARS-CoV-2 were included from three centers. Read More

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Renal involvement of a patient with Crohn´s disease: A case report.

Cesk Patol 2021 ;57(2):109-112

Inflammatory bowel disease (IBD) is a group of chronic relapsing intestinal inflammatory processes primarily represented by ulcerative colitis (UC) and Crohn´s disease (CD). Nearly half of IBD cases are followed by extraintestinal complications and renal involvement can occur independatly or along with other complications and are described with the patients sufferring from UC or CD. Most frequent renal involvement is nephrolithiasis, tubulointerstinal nephritis, different kinds of glomerulonephritis and AA amyloidosis. Read More

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Severe cutaneous adverse reactions in Asians: Trends observed in culprit anti-seizure medicines using VigiBase®.

Seizure 2021 Jul 13;91:332-338. Epub 2021 Jul 13.

Postgraduate Institute of Medical Education & Research, Chandigarh 160012, India.

Purpose: Diverse ethnic genetic populations display variability in the risk regarding anti-seizure medicine (ASM)-induced severe cutaneous adverse reactions (SCARs). However, clinical and epidemiological data on ASM-induced SCARs in Asians is limited.

Methods: We conducted a retrospective, post-market study until April 30, 2020 using VigiBase® for demographic characteristics, causative ASMs, complications and mortality. Read More

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Partition of Pectoralis Major Musculocutaneous Flap as a Salvage Procedure for Simultaneous Coverage of the Exposed Carotid Artery and Reconstruction of Cervical Esophagus.

Ann Plast Surg 2021 Jul 13. Epub 2021 Jul 13.

From the Department of Plastic Surgery, China Medical University Hospital, Taichung, Taiwan Plastic Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy Division of Plastic and Reconstructive Surgery, Department of Surgery, Mayo Clinic, Rochester, MN Department of Plastic and Reconstructive Surgery, Sapienza University of Rome, Umberto I University Hospital, Rome, Italy Plastic Surgery Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.

Background: In advanced pharyngoesophageal cancer patients, a critical event is represented by the failure of primary reconstruction with exposure of the carotid artery and partial or total defect of the cervical esophagus. For these high-risk patients, a partitioned pectoralis major musculocutaneous (PMMC) flap can prevent carotid blowout and provide skin for simultaneous esophageal reconstruction.

Methods: Twenty-six patients needing pharyngoesophageal reconstruction together with coverage of carotid artery exposure were included in this retrospective case series. Read More

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Aligning Patient Acuity with Resource Intensity after Major Surgery: A Scoping Review.

Ann Surg 2021 Jul 14. Epub 2021 Jul 14.

Department of Surgery, University of Florida Health, Gainesville, FL, USA Department of Medicine, University of Florida Health, Gainesville, FL, USA Departments of Anesthesiology, Orthopedics, and Information Systems/Operations Management, University of Florida Health, Gainesville, FL, USA Department of Health Outcomes & Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL, USA Departments of Biomedical Engineering, Computer and Information Science and Engineering, and Electrical and Computer Engineering, University of Florida, Gainesville, Florida, USA Precision and Intelligent Systems in Medicine (Prisma), University of Florida, Gainesville, FL, USA.

Objective: Develop unifying definitions and paradigms for data-driven methods to augment postoperative resource intensity decisions.

Summary Background Data: Postoperative level-of-care assignments and frequency of vital sign and laboratory measurements (i.e. Read More

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Association between socioeconomic position and diabetic foot ulcer outcomes: a population-based cohort study in South Korea.

BMC Public Health 2021 Jul 14;21(1):1395. Epub 2021 Jul 14.

Department of Plastic and Reconstructive Surgery, Seoul National University Boramae Hospital, Seoul National University College of Medicine, Seoul, 07061, Republic of Korea.

Background: Low socioeconomic position (SEP) is associated with a high incidence of diabetic foot ulcers (DFUs). However, reports on the association between SEP and DFU outcomes are limited. Therefore, in this study, we investigated this association and determined the prognostic factors of DFU outcomes. Read More

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Long-term consequences of previous preeclampsia and complicated pregnancy: analysis of echocardiographic aspects.

J Cardiovasc Med (Hagerstown) 2021 Jul 12. Epub 2021 Jul 12.

Internal Medicine Prof. Borghi Unit, Department of Medical and Surgical Sciences, S.Orsola-Malpighi University Hospital, Bologna, Italy.

Introduction: Preeclampsia has an increased risk of cardiovascular events later in life. In this retrospective study, we evaluated echocardiographic aspects in women with history of preeclampsia or preeclampsia-related complications in their previous pregnancies.

Materials And Methods: Consecutive women receiving echocardiography during daily clinical echolab activity were studied using complete echocardiographic examination data and anamnestic data collection of hypertension, diabetes, dyslipidemia, and rheumatic diseases. Read More

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HIPEC-Induced Acute Kidney Injury: A Retrospective Clinical Study and Preclinical Model.

Ann Surg Oncol 2021 Jul 14. Epub 2021 Jul 14.

Department of General, Visceral and Transplantation Surgery, University Hospital Heidelberg, Heidelberg, Germany.

Background: Hyperthermic intraperitoneal chemotherapy (HIPEC) combined with cytoreductive surgery (CRS) is the treatment of choice for selected patients with peritoneal malignancies. HIPEC is accompanied by moderate-to-high patient morbidity, including acute kidney injury. The significance of nephrotoxic agents such as cisplatin versus hyperthermia in HIPEC-induced nephrotoxicity has not been defined yet. Read More

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911 EMS Activations by Pregnant Patients in Maryland (USA) during the COVID-19 Pandemic.

Prehosp Disaster Med 2021 Jul 14:1-6. Epub 2021 Jul 14.

Department of Emergency Medicine, Johns Hopkins School of Medicine, Baltimore, MarylandUSA.

Introduction: In the early phase of the coronavirus disease 2019 (COVID-19) pandemic, United States Emergency Medical Services (EMS) experienced a decrease in calls, and at the same time, an increase in out-of-hospital deaths. This finding led to a concern for the implications of potential delays in care for the obstetric population.

Hypothesis/problem: This study examines the impact of the pandemic on prehospital care amongst pregnant women. Read More

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"Nerve-sparing" laparoscopic treatment of parametrial ectopic pregnancy.

Fertil Steril 2021 Jul 9. Epub 2021 Jul 9.

Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", Trieste, Italy; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.

Objective: To demonstrate laparoscopic surgical management of parametrial ectopic pregnancy.

Design: Video presentation of laparoscopic nerve-sparing treatment of parametrial pregnancy.

Setting: Tertiary university center. Read More

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Preoperative Opioid Use Is Associated With Higher Revision Rates in Total Joint Arthroplasty: A Systematic Review.

J Arthroplasty 2021 Jun 24. Epub 2021 Jun 24.

The Stavros Niarchos Foundation Complex Joint Reconstruction Center, Hospital for Special Surgery, New York, NY; Hadassah Medical Center, Jerusalem, Israel.

Background: Although preoperative opioid use has been associated with poor postoperative patient-reported outcome measures and delayed return to work in patients undergoing total joint arthroplasty, direct surgery-related complications in patients on chronic opioids are still not clear. Thus, we sought to perform a systematic review of the literature to evaluate the influence of preoperative opioid use on postoperative complications and revision following primary total joint arthroplasty.

Methods: Following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, we queried PubMed, EMBASE, the Cochrane Library, and the ISI Web of Science for studies investigating the influence of preoperative opioid use on postoperative complications following total hip arthroplasty and total knee arthroplasty up to May 2020. Read More

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Oncologists' Perspective on Dental Care Around the Treatment of Head and Neck Cancer: A Pattern of Practice Survey.

JCO Oncol Pract 2021 Jul 9:OP2000913. Epub 2021 Jul 9.

Department of Oral Medicine, Atrium Health, Charlotte, NC.

Purpose: Patients with head and neck cancer are at risk of long-term dental complications. Proper dental assessment pre- and post-treatment can improve outcomes but is logistically challenging. We surveyed oncologists to better understand their perspectives surrounding dental care in this unique population. Read More

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The Efficacy of Adalimumab as an Initial Treatment in Patients with Behçet's Retinal Vasculitis.

Front Pharmacol 2021 22;12:609148. Epub 2021 Jun 22.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

No study has evaluated the effectiveness of Adalimumab (ADA) as first-line in treatment-naïve patients with retinal vasculitis due to Behçet's Uveitis (BU). To compare the efficacy of ADA plus conventional therapy and conventional therapy alone as initial treatments in naïve BU patients characterized by retinal vasculitis. Medical records of BU patients characterized by retinal vasculitis treated with conventional therapy (CT, refers to glucocorticoid and immunosuppressive agents) alone or ADA plus conventional therapy with at least 6 months of follow-up between February 2015 and June 2020 were analyzed. Read More

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Endovascular Repair of Primary Thoracic Aortic Mural Thrombus Following Upper Limb Embolization.

Braz J Cardiovasc Surg 2021 Jul 7. Epub 2021 Jul 7.

Department of Vascular and Endovascular Surgery, ARNAS Civico Di Cristina Benfratelli, Palermo, Italy.

We report the case of a 41-year-old female who presented with left upper limb embolization due to primary thoracic aortic mural thrombus; this latter represented an uncommon condition with difficult diagnosis and a high rate of life-threatening complications. Upper extremities embolization is extremely rare because it usually occurs in the lower limbs. Management strategy is still controversial, and no clear guidelines indicate superiority of either conservative or invasive treatment approach to date. Read More

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Problems, complications, and reinterventions in 4893 onlay humeral lateralized reverse shoulder arthroplasties: a systematic review (part I-complications).

J Orthop Traumatol 2021 Jul 8;22(1):27. Epub 2021 Jul 8.

Department of Orthopaedic and Trauma Surgery, Ospedale Buon Consiglio Fatebenefratelli, Via A. Manzoni 220, 80123, Napoli, NA, Italy.

Background: Several modifications to the original Grammont reverse shoulder arthroplasty (RSA) design have been proposed to prevent distinctive issues, such as both glenoid and humeral lateralization. The aim of this systematic review was to determine rates of problems, complications, reoperations, and revisions after onlay lateralized humeral stem RSA, hypothesizing that these are design related.

Methods: This systematic review was performed in accordance with the PRISMA statement guidelines. Read More

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Common elective orthopaedic procedures and their clinical effectiveness: umbrella review of level 1 evidence.

BMJ 2021 07 7;374:n1511. Epub 2021 Jul 7.

National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol, Bristol, UK.

Objective: To determine the clinical effectiveness of common elective orthopaedic procedures compared with no treatment, placebo, or non-operative care and assess the impact on clinical guidelines.

Design: Umbrella review of meta-analyses of randomised controlled trials or other study designs in the absence of meta-analyses of randomised controlled trials.

Data Sources: Ten of the most common elective orthopaedic procedures-arthroscopic anterior cruciate ligament reconstruction, arthroscopic meniscal repair of the knee, arthroscopic partial meniscectomy of the knee, arthroscopic rotator cuff repair, arthroscopic subacromial decompression, carpal tunnel decompression, lumbar spine decompression, lumbar spine fusion, total hip replacement, and total knee replacement-were studied. Read More

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TCF7L2 gene polymorphism as a risk for type 2 diabetes mellitus and diabetic microvascular complications.

Mol Biol Rep 2021 Jun 7;48(6):5283-5290. Epub 2021 Jul 7.

Clinical Pathology Department, Faculty of Medicine, Menoufia University, Shibīn al-Kawm, Egypt.

Background: Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic condition with various genetics and environmental influences that affects the capacity of the body to produce or use insulin resulting in hyperglycemia, which may lead to variable complications. It is one of the world's rising health problems. There is emerging evidence that some genetic polymorphisms can impact the risk of evolving T2DM. Read More

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Dermatologic Complications Following Cosmetic and Reconstructive Plastic Surgery: A Systematic Review of the Literature.

Aesthetic Plast Surg 2021 Jul 6. Epub 2021 Jul 6.

Division of Plastic Surgery, Department of Surgery, G5-347 Clinical Sciences Center, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI, 53711, USA.

Purpose: Plastic surgery procedures, including minimally invasive cosmetic procedures, continue to grow in popularity. Although dermatologic complications following plastic surgery procedures are rare, the authors have encountered several of these complications in their practice, including herpes simplex virus (HSV-1) and varicella zoster virus (VZV) infections, pyoderma gangrenosum (PG), contact dermatitis, and suture hypersensitivity. These cases prompted a systematic literature review of dermatologic complications following plastic surgery procedures. Read More

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Palliative outpatient parenteral antibiotic therapy: a review of 5 years of patient data.

JAC Antimicrob Resist 2020 Sep 6;2(3):dlaa052. Epub 2020 Aug 6.

Division of Primary Care, University of Nottingham, University Park, Nottingham NG7 2RD, UK.

Objectives: A review of patients requiring lifelong antibiotics to control, rather than cure, infection was performed ['palliative outpatient parenteral antibiotic therapy (OPAT)']. This was to evaluate emerging themes and complications. The aim was to aid in the management of such patients. Read More

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September 2020

Clinical Efficacy and Safety Comparison of Rivaroxaban and Dabigatran for Nonvalvular Atrial Fibrillation Patients Undergoing Percutaneous Left Atrial Appendage Closure Operation.

Front Pharmacol 2021 18;12:614762. Epub 2021 Jun 18.

Department of Pharmacy, Zhongshan Hospital, Fudan University, Shanghai, China.

Due to the clinical complexity of warfarin, novel oral anticoagulation (NOAC) has been a feasible and safe alternative anticoagulant approach during left atrial appendage closure (LAAC). This study was designed to compare the efficacy and safety of rivaroxaban and dabigatran for nonvalvular atrial fibrillation patients undergoing percutaneous LAAC. One single and prospective cohort study was performed among patients who received anticoagulation with dabigatran or rivaroxaban. Read More

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Maternal mortality during the COVID-19 pandemic in Mexico: a preliminary analysis during the first year.

BMC Public Health 2021 07 2;21(1):1297. Epub 2021 Jul 2.

Department of Environmental and Occupational Health, School of Public Health, Texas A&M University, 212 Adriance Lab Road, College Station, TX, 77843, USA.

Background: In Mexico, the COVID-19 pandemic led to preventative measures such as confinement and social interaction limitations that paradoxically may have aggravated healthcare access disparities for pregnant women and accentuated health system weaknesses addressing high-risk patients' pregnancies. Our objective is to estimate the maternal mortality ratio in 1 year and analyze the clinical course of pregnant women hospitalized due to acute respiratory distress syndrome and COVID-19.

Methods: A retrospective surveillance study of the national maternal mortality was performed from February 2020-February 2021 in Mexico related to COVID-19 cases in pregnant women, including their outcomes. Read More

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Clinical presentation and management of childhood intussusception in South Africa.

Pediatr Surg Int 2021 Jul 2. Epub 2021 Jul 2.

South African Medical Research Council: Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Purpose: We assessed management and outcomes for intussusception at nine academic hospitals in South Africa.

Methods: Patients ≤ 3 years presenting with intussusception between September 2013 and December 2017 were prospectively enrolled at all sites. Additionally, patients presenting between July 2012 and August 2013 were retrospectively enrolled at one site. Read More

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Endovascular treatment of chronic hemoptysis in patients with pulmonary tuberculosis.

Acta Biomed 2021 07 1;92(3):e2021201. Epub 2021 Jul 1.

Advanced Biomedical Sciences Department, University Federico II of Naples (UNINA), via S. Pansini 5, I-80131.

Background: We aimed to demonstrate the safety and efficacy of bronchial artery embolization (BAE) in patients with pulmonary tuberculosis in the planned management of "mild" hemoptysis. This treatment, already widely documented and used as a life-saving therapy in an emergency regimen, if properly planned in poorly controlled patients through medical therapy alone, can provide a valid opportunity by reducing the frequency and extent of non-fatal bleeding, but which still worsen the quality of life of these already significantly traumatized patients.

Methods: All procedures were conducted through a right common femoral access with a 5 Fr catheter and a 2. Read More

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