Curr Biol 2021 Jul 15. Epub 2021 Jul 15.
MRC Laboratory for Molecular Cell Biology, University College London, London, UK; Institute for the Physics of Living Systems, University College London, London, UK; MRC Laboratory of Molecular Cell Biology, Cambridge, UK. Electronic address:
Although nuclei are the defining features of eukaryotes, we still do not fully understand how the nuclear compartment is duplicated and partitioned during division. This is especially the case for organisms that do not completely disassemble their nuclear envelope upon entry into mitosis. In studying this process in Drosophila neural stem cells, which undergo asymmetric divisions, we find that the nuclear compartment boundary persists during mitosis thanks to the maintenance of a supporting nuclear lamina. Read More