21,948 results match your criteria complete renal

Rare case report of anorectal malformation and intestinal atresia.

Int J Surg Case Rep 2021 Apr 30;82:105945. Epub 2021 Apr 30.

Division of Pediatric Surgery, Department of Surgery, Loma Linda University Medical Center, United States of America. Electronic address:

Introduction: Intestinal malformations, such as intestinal atresia, malrotation, and anorectal malformation, are rare events, but concurrent intestinal atresia and anorectal malformation are rare in combination. These anomalies have similar in utero and perinatal symptoms, which can make the diagnosis of both defects prenatally challenging.

Presentation Of Case: We present a case of a male infant with a prenatal diagnosis of truncus arteriosus who on a 32-week routine prenatal ultrasound was suspected to have an intestinal malformation. Read More

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Kidney Transplantation in Monoclonal Immunoglobulin Deposition Disease: A Report of 6 Cases.

Am J Kidney Dis 2021 May 4. Epub 2021 May 4.

Nephrology and Renal Transplantation Department, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain. Institut d'Investigacions Biomediques August Pi I Sunyer (IDIBAPS), Barcelona, Spain; Amyloidosis and Myeloma Unit.Hospital Clínic de Barcelona; Centro de Referencia en Enfermedad Glomerular Compleja del Sistema Nacional de Salud (CSUR), Barcelona, Spain. Electronic address:

Monoclonal immunoglobulin deposition disease (MIDD) usually leads to kidney failure. Treatment of patients with a bortezomib-based regimen followed by autologous stem cell transplantation has been increasingly used, with improvements in the response rates and the allograft outcomes in kidney transplant recipients. The objective of this report was to analyze the outcomes of 6 patients who underwent kidney transplantation in our institution after treatment of MIDD between 2010 and 2019. Read More

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Transvenous Phrenic Nerve Stimulation for Treatment of Central Sleep Apnea: Five-Year Safety and Efficacy Outcomes.

Nat Sci Sleep 2021 29;13:515-526. Epub 2021 Apr 29.

The Ohio State University, Columbus, OH, USA.

Background: The remedē System Pivotal Trial was a prospective, multi-center, randomized trial demonstrating transvenous phrenic nerve stimulation (TPNS) therapy is safe and effectively treats central sleep apnea (CSA) and improves sleep architecture and daytime sleepiness. Subsequently, the remedē System was approved by FDA in 2017. As a condition of approval, the Post Approval Study (PAS) collected clinical evidence regarding long-term safety and effectiveness in adults with moderate to severe CSA through five years post implant. Read More

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Association between diuretic administration before diagnosis and incidence of acute kidney injury in patients with minimal change disease: A single-center observational study.

Medicine (Baltimore) 2021 May;100(18):e25845

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

Abstract: We examined the association between diuretic administration before the diagnosis of minimal change disease and the incidence of acute kidney injury. Moreover, we examined whether the use of diuretics affected the time to complete remission in adults with such disease.The present study was a single-center, retrospective, observational cohort study. Read More

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A Quality Improvement Intervention to Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) in Patients With Chronic Kidney Disease: Clinical Research Protocol of a Cluster-Randomized Clinical Trial.

Can J Kidney Health Dis 2021 15;8:2054358121997266. Epub 2021 Apr 15.

ICES, ON, Canada.

Background: Many patients with kidney failure will live longer and healthier lives if they receive a kidney transplant rather than dialysis. However, multiple barriers prevent patients from accessing this treatment option.

Objective: To determine if a quality improvement intervention provided in chronic kidney disease (CKD) programs (vs. Read More

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Potentially inappropriate primary care prescribing in people with chronic kidney disease: a cross-sectional analysis of a large population cohort.

Br J Gen Pract 2020 Dec 14. Epub 2020 Dec 14.

Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh.

Background: Many drugs should be avoided or require dose-adjustment in chronic kidney disease (CKD). Previous estimates of potentially inappropriate prescribing rates have been based on data on a limited number of drugs, and mainly in secondary care settings.

Aim: To determine the prevalence of contraindicated and potentially inappropriate primary care prescribing in a complete population of people with known CKD. Read More

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December 2020

Extensive subcutaneous fat necrosis complicated by neonatal hypercalcaemia.

Acta Biomed 2021 Apr 30;92(S1):e2021081. Epub 2021 Apr 30.

king abdulaziz university hospital.

subcutaneous fat necrosis is a benign and often self-limiting inflammatory disorder experienced by newborns who were exposed to perinatal stress in the form of asphyxia, hypothermia, cord prolapse, and/or sepsis. lesions are usually benign and self-limiting, with complete resolution anticipated within a few weeks up to 6 months. they can be accompanied by multiple complications. Read More

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Erythropoietin-Associated Posterior Reversible Encephalopathy Syndrome.

Neurologist 2021 May 5;26(3):98-100. Epub 2021 May 5.

Department of Neuroscience, NYU Winthrop Hospital, Mineola, NY.

Introduction: This case demonstrates an underrecognized cause of posterior reversible encephalopathy syndrome (PRES).

Case Report: We report a 51-year-old male with a history of essential hypertension without preexisting renal impairment who presented with 3 days of occipital headache and convulsive status epilepticus in the setting of refractory hypertension. He had been receiving outpatient human recombinant erythropoietin injections for virally mediated bone marrow suppression, which worsened his baseline hypertension. Read More

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[Medical management of uric acid renal stones, case description.]

Arch Esp Urol 2021 May;74(4):442-445

Servicio de Urología. Hospital Universitario San Cecilio. Granada. España.

Uric acid renal stones are a frequent and important part of our clinical practice. Conservative treatment through diet and urine alkalinization with citrate and teobromina seem a promising combination for treatment of those stones. We show on our cases a complete resolution of staghorn stone at 12 weeks of allopurinol and lit-control pH Up treatment, without adverse events and avoiding surgical treatment. Read More

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[Evaluation of ischemia-modified albumin in obstructive renal injury.]

Arch Esp Urol 2021 May;74(4):427-434

SBU Haydarpasa Numune SUAM. Department of Urology. Istanbul. Turkey.

Objectives: This study was aimed at assessing the ability of ischemia-modified albumin (IMA) to predict renal injury by associating biochemical, functional, and pathological findings with various degrees of ureteral obstruction.

Methods: Twenty-four rats were randomized into three groups, and their blood was sampled to determine the creatinine and IMA values and renal scintigraphy was done at the start and on postoperative day 7. In the sham group, the ureter was untouched; in the partial group, the ureter was gently embedded into the psoas muscle; and in the complete group, the ureter was compathologically, and all parameters were statistically evaluated. Read More

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Comparative evaluation of upper versus lower calyceal approach in percutaneous nephrolithotomy (PCNL) for managing renal calculi.

J Pak Med Assoc 2021 Feb;71(2(B)):602-607

College of Physicians and Surgeons of Pakistan, Karachi.

Objective: To compare upper versus lower calyceal approaches in percutaneous nephrolithotomy for managing renal calculi.

Methods: The retrospective study was conducted in the Department of Urology, The Kidney Centre Post-Graduate Training Institute, Karachi, and comprised data of patients who underwent percutaneous nephrolithotomy from January 2014 to January 2015. Patients were divided into upper pole puncture group A and lower pole puncture group B. Read More

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February 2021

Elimination of Hepatitis C Virus in a Dialysis Population: A Collaborative Care Model in Taiwan.

Am J Kidney Dis 2021 Apr 30. Epub 2021 Apr 30.

Ministry of Health and Welfare, Taipei, Taiwan.

Rationale & Objective: Hemodialysis facilities are high-risk environments for hepatitis C virus (HCV). Eliminating HCV from all dialysis facilities in a community may be achieved more effectively under a collaborative care model.

Study Design: Quality improvement study of multidisciplinary collaborative care teams including nephrologists, gastroenterologists and public health practitioners. Read More

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Surgical Explantation of a Fenestrated Endovascular Abdominal Aortic Aneurysm Repair Device Complicated by Aorto-Enteric Fistula.

EJVES Vasc Forum 2021 19;50:12-18. Epub 2020 Dec 19.

Vascular Surgery Department, Bordeaux University Hospital, Bordeaux, France.

Introduction: Alarming outcomes have been reported following infected endovascular aortic aneurysm repair (EVAR) device explantation. Infected fenestrated EVAR (FEVAR) exposes patients to even worse procedural risks.

Report: A 67 year old man with a prior history of FEVAR presented with impaired general condition, abdominal and back pain, and increased C reactive protein. Read More

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December 2020

The Incremental Prognostic Value of the Clinical Residual SYNTAX Score for Patients With Chronic Renal Insufficiency Undergoing Percutaneous Coronary Intervention.

Front Cardiovasc Med 2021 15;8:647720. Epub 2021 Apr 15.

The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, China.

The residual SYNTAX score (RSS) is considered a powerful prognostic indicator for determining a reasonable revascularization strategy in patients undergoing percutaneous coronary intervention (PCI), but the absence of clinical parameters is one of the limitations of RSS, especially in the chronic renal insufficiency (CRI) comorbidity setting. The present work aimed to investigate the incremental prognostic value of clinical residual SYNTAX score (CRSS) compared with RSS in CRI cases after PCI. Totally 2,468 consecutive CRI cases who underwent PCI from January 2014 to September 2017 were included in this retrospective analysis. Read More

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Unilateral Urogenital Disontogeny in a Dog.

Case Rep Vet Med 2021 13;2021:8831551. Epub 2021 Apr 13.

School of Biosciences and Veterinary Medicine, University of Camerino, via Circonvallazione, 93, 62024 Matelica, Italy.

The purpose of this report was to describe an uncommon congenital anomaly in a dog. An 8-year-old, mixed-breed, male dog, was referred because of progressive difficulties on defecation. A complete diagnostic work-up (hematological analysis, radiology, ultrasound, and computed tomography), followed by surgery and histopathology, allowed us to diagnose the condition as unilateral urogenital disontogeny. Read More

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Rifampicin-Associated Secondary Minimal Change Disease Presenting with Nephrotic Syndrome in a Pulmonary Tuberculosis Patient.

Case Rep Nephrol 2021 14;2021:5546942. Epub 2021 Apr 14.

Department of Medicine, S.M.M.H. Government Medical College, Saharanpur, Uttar Pradesh, India.

Various extraglomerular disease processes have been associated with drug-induced secondary minimal change disease (MCD). In a majority of cases, preferably, a hypersensitivity reaction appears to be involved, and in some cases, there is direct toxic effect over glomerular capillaries. There are several reports to demonstrate that rifampicin has been associated with various nephrotoxic adverse effects, but rifampicin-induced secondary minimal change disease (MCD) is very rare. Read More

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eSIMPLER: A Dynamic, Electronic Health Record-Integrated Checklist for Clinical Decision Support During PICU Daily Rounds.

Pediatr Crit Care Med 2021 May 3. Epub 2021 May 3.

Division of Critical Care Medicine, Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, MA. Computational Health Informatics Program, Boston Children's Hospital, Boston, MA. Department of Anaesthesia, Harvard Medical School, Boston, MA. Department of Cardiovascular and Critical Care Nursing, Medical-Surgical Intensive Care Unit, Boston Children's Hospital, Boston, MA. Anesthesia Information Services, Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, MA.

Objectives: Design, implement, and evaluate a rounding checklist with deeply embedded, dynamic electronic health record integration.

Design: Before-after quality-improvement study.

Setting: Quaternary PICU in an academic, free-standing children's hospital. Read More

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Significant Aortic Neck Dilation Occurs Following Repair of Juxtarenal Aneurysms with Fenestrated Endovascular Aneurysm Repair.

J Vasc Surg 2021 Apr 27. Epub 2021 Apr 27.

Division of Vascular Surgery, Department of Surgery. University of Washington, Seattle WA.

Objectives: Aortic neck dilation is a reported mode of failure and can be associated with aneurysm sac expansion following standard endovascular repair of aortic aneurysms. Fenestrated repairs of the juxtarenal segment increase the seal zone length and are often utilized to treat this disease progression. However, the frequency and risk factors for neck dilation following fenestrated repairs is unknown. Read More

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Infectious complications and graft outcome following treatment of acute antibody-mediated rejection after kidney transplantation: A nationwide cohort study.

PLoS One 2021 30;16(4):e0250829. Epub 2021 Apr 30.

Transplantation Center, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.

Acute antibody-mediated rejection (AMR) remains a challenge after kidney transplantation (KT). As there is no clear-cut treatment recommendation, accurate information on current therapeutic strategies in real-life practice is needed. KT recipients from the multicenter Swiss Transplant Cohort Study treated for acute AMR during the first post-transplant year were included retrospectively. Read More

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Infantile systemic lupus erythematous presenting as nephrotic syndrome in a 12-month-old boy: a case report.

Turk J Pediatr 2021 ;63(2):339-343

Departments of Pediatric Nephrology, Ankara University Faculty of Medicine, Ankara, Turkey.

Background: Systemic lupus erythematous (SLE) is extremely rare in infants and has been reported to be a much more severe disease with higher prevalence of critical organ involvement. Herein we present the clinical and laboratory features of infantile SLE (iSLE) with an onset of nephrotic syndrome (NS) during the first year of life.

Case: A 12-month-old boy was suffering from generalized edema for two months. Read More

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January 2021

The Use of Imaging Techniques in Chronic Kidney Disease-Mineral and Bone Disorders (CKD-MBD)-A Systematic Review.

Diagnostics (Basel) 2021 Apr 26;11(5). Epub 2021 Apr 26.

Department of Dialysis AURA Nord Saint Ouen, 93400 Saint Ouen, France.

Although frequently silent, mineral and bone disease (MBD) is one of the most precocious complication of chronic kidney disease (CKD) and is omnipresent in patients with CKD stage 5. Its pathophysiology is complex, but basically, disturbances in vitamin D, phosphate, and calcium metabolism lead to a diverse range of clinical manifestations with secondary hyperparathyroidism usually being the most frequent. With the decline in renal function, CKD-MBD may induce microstructural changes in bone, vascular system and soft tissues, which results in macrostructural lesions, such as low bone mineral density (BMD) resulting in skeletal fractures, vascular and soft tissue calcifications. Read More

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Prognostic Factors and Current Treatment Strategies for Renal Cell Carcinoma Metastatic to the Brain: An Overview.

Cancers (Basel) 2021 Apr 27;13(9). Epub 2021 Apr 27.

Department of Biomedical Sciences and Human Oncology, University of Bari, 70122 Bari, Italy.

Renal cell carcinoma (RCC) is one of primary cancers that frequently metastasize to the brain. Brain metastasis derived from RCC has the propensity of intratumoral hemorrhage and relatively massive surrounding edema. Moreover, it confers a grim prognosis in a great percentage of cases with a median overall survical (mOS) around 10 months. Read More

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Predictive Value of Pro-BNP for Heart Failure Readmission after an Acute Coronary Syndrome.

J Clin Med 2021 Apr 13;10(8). Epub 2021 Apr 13.

Cardiology Department, Hospital Universitario de San Juan, 03550 Alicante, Spain.

Background: N-terminal pro-brain natural peptide (NT-pro-BNP) is a well-established biomarker of tissue congestion and has prognostic value in patients with heart failure (HF). Nonetheless, there is scarce evidence on its predictive capacity for HF re-admission after an acute coronary syndrome (ACS). We performed a prospective, single-center study in all patients discharged after an ACS. Read More

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Long Non-Coding Expression Correlates with Renal Cell Carcinoma Metastasis and Aggressiveness.

Noncoding RNA 2021 Apr 10;7(2). Epub 2021 Apr 10.

Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.

Long non-coding RNAs (lncRNAs) can be specifically expressed in different tissues and cancers. By controlling the gene expression at the transcriptional and translational levels, lncRNAs have been reported to be involved in tumor growth and metastasis. Recent data demonstrated that multiple lncRNAs have a crucial role in renal cell carcinoma (RCC) progression-the most common malignant urogenital tumor. Read More

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SARS-CoV-2 Renal Impairment in Critical Care: An Observational Study of 42 Cases (Kidney COVID).

J Clin Med 2021 Apr 8;10(8). Epub 2021 Apr 8.

Department of Anesthesiology and Intensive Care, Hôpital Saint-Antoine, Assistance Publique-Hôpitaux de Paris, 75012 Paris, France.

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection leads to 5% to 16% hospitalization in intensive care units (ICU) and is associated with 23% to 75% of kidney impairments, including acute kidney injury (AKI). The current work aims to precisely characterize the renal impairment associated to SARS-CoV-2 in ICU patients. Forty-two patients consecutively admitted to the ICU of a French university hospital who tested positive for SARS-CoV-2 between 25 March 2020, and 29 April 2020, were included and classified in categories according to their renal function. Read More

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Efficacy and Safety of Nivolumab and Ipilimumab for Advanced or Metastatic Renal Cell Carcinoma: A Multicenter Retrospective Cohort Study.

Curr Oncol 2021 Apr 3;28(2):1402-1411. Epub 2021 Apr 3.

Department of Urology, Graduate School of Medicine, Gifu University, Gifu 5011194, Japan.

We conducted a multicenter, retrospective study to evaluate the efficacy and safety of combination nivolumab plus ipilimumab (NIVO+IPI) in 35 patients with advanced or metastatic renal cell carcinoma (mRCC). In this study, we focused on patients who received NIVO+IPI and were stratified into intermediate- or poor-risk disease according to the International Metastatic Renal Cell Carcinoma Database Consortium model at five institutions in Japan. The primary endpoint was overall survival (OS). Read More

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A Uremic Goat Model Created by Subtotal Renal Artery Embolization and Gentamicin.

Biology (Basel) 2021 Apr 3;10(4). Epub 2021 Apr 3.

Department of Nephrology and Hypertension, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.

A large animal model of (end-stage) kidney disease (ESKD) is needed for the preclinical testing of novel renal replacement therapies. This study aimed to create stable uremia via subtotal renal artery embolization in goats and induce a temporary further decline in kidney function by administration of gentamicin. Renal artery embolization was performed in five Dutch white goats by infusing polyvinyl alcohol particles in branches of the renal artery, aiming for the embolization of ~80% of one kidney and complete embolization of the contralateral kidney. Read More

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A Prospective Study on Long-Term Clinical Outcomes of Patients With Lupus Nephritis Treated With an Intensified B-Cell Depletion Protocol Without Maintenance Therapy.

Kidney Int Rep 2021 Apr 3;6(4):1081-1087. Epub 2021 Feb 3.

CMID-Nephrology and Dialysis Unit (ERK-net Member), Center of Research of Immunopathology and Rare Diseases, Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, Department of Clinical and Biological Sciences, University of Turin and S. Giovanni Bosco Hub Hospital, Turin, Italy.

Background: We aimed to investigate the safety and efficacy of an intensified B-cell depletion induction therapy (IBCDT) without immunosuppressive maintenance regimen compared with standard of care in biopsy-proven lupus nephritis (LN).

Methods: Thirty patients were administered an IBCDT (4 weekly rituximab [RTX] 375 mg/m and 2 more doses after 1 and 2 months; 2 infusions of 10 mg/kg cyclophosphamide [CYC], 3 methylprednisolone pulses), followed by oral prednisone (tapered to 5 mg/d by the third month). No immunosuppressive maintenance therapy was given. Read More

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