J Chromatogr B Analyt Technol Biomed Life Sci 2007 Jun 18;853(1-2):138-46. Epub 2007 Mar 18.
HFL, Newmarket Road, Fordham, Cambridgeshire CB7 5WW, United Kingdom.
Phytoestrogens are currently the subject of intense study owing to their potential protective effects against a number of complex diseases. However, in order to investigate the interactions between phytoestrogens and disease state effectively, it is necessary to have analytical methods which are sensitive, reproducible, and require low sample volumes. We report an assay for three isoflavones (daidzein, genistein, and glycitein), two metabolites of daidzein (equol and O-desmethylangolensin), three lignans (secoisolariciresinol, enterodiol, and enterolactone), and one flavanone (naringenin) in human urine and serum. Read More