1,173 results match your criteria compared monopolar

Gene transfer by electroporation with high frequency bipolar pulses in vitro.

Bioelectrochemistry 2021 Mar 22;140:107803. Epub 2021 Mar 22.

University of Ljubljana, Faculty of Electrical Engineering, Tržaška 25, 1000 Ljubljana, Slovenia. Electronic address:

High-frequency bipolar pulses (HF-BP) have been demonstrated to be efficient for membrane permeabilization and irreversible electroporation. Since membrane permeabilization has been achieved using HF-BP pulses we hypothesized that with these pulses we can also achieve successful gene electrotransfer (GET). Three variations of bursts of 2 µs bipolar pulses with 2 µs interphase delay were applied in HF-BP protocols. Read More

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Monopolar gene electrotransfer enhances plasmid DNA delivery to skin.

Bioelectrochemistry 2021 Apr 17;140:107814. Epub 2021 Apr 17.

Department of Medical Engineering, University of South Florida, Tampa, FL, United States.

A novel monopolar electroporation system and methodologies were developed for in vivo electroporation intended for potential clinical applications such as gene therapy. We hypothesized that an asymmetric anode/cathode electrode applicator geometry could produce favorable electric fields for electroporation, without the typical drawback associated with traditional needle and parallel plate geometries. Three monopolar electrode applicator prototypes were built and tested for gene delivery of reporter genes to the skin in a guinea pig model. Read More

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Proximity resonances of water-entrained air bubbles near acoustically reflecting boundaries.

J Acoust Soc Am 2021 Apr;149(4):2477

Institute of Physics, Pontificia Universidad Católica de Chile, Santiago, Región Metropolitana, Chile.

The acoustic resonances of radiatively damped air bubbles in water near reflecting boundaries are investigated by representing the bubble and its image by two bubbles in a full space, ensonified by two incident fields. Results obtained using an analytic monopole theory are compared with those of a coupled spherical harmonic technique and a boundary element method. Near a rigid boundary, the resonance frequency is reduced, and the response characteristics are determined by the predominant monopolar character of the individual bubble motion, with small changes in peak amplitude and Q. Read More

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Very-Low Energy Monopolar Reduces Post-Tonsillectomy Hemorrhage Versus Standard Energy Techniques.

Laryngoscope 2021 Apr 27. Epub 2021 Apr 27.

Dr Bing Zhang Department of Statistics, University of Kentucky, Lexington, Kentucky, U.S.A.

Objectives/hypothesis: To compare rates of post-tonsillectomy hemorrhage (PTH) between a very-low energy transfer monopolar technique (VLET) and standard energy techniques.

Study Design: Retrospective controlled cohort study.

Methods: All tonsillectomies performed by practice physicians during the period January 1, 2010 to August 31, 2019 were identified. Read More

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The PLASMA System for Transurethral Resection of the Prostate: A NICE Medical Technologies Guidance Update.

Appl Health Econ Health Policy 2021 Apr 26. Epub 2021 Apr 26.

Cedar, Cardiff & Vale University Health Board, Cardiff, UK.

Lower urinary tract symptoms (LUTS) in men commonly occur as a consequence of benign prostatic hyperplasia (BPH), also known as prostate enlargement. Treatments for this can involve electrosurgical removal of a section of the prostate via transurethral resection of the prostate (TURP). This can be performed using either monopolar or bipolar electrosurgery. Read More

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Switching monopolar radiofrequency ablation improves long-term outcomes of medium-sized hepatocellular carcinoma.

Eur Radiol 2021 Apr 25. Epub 2021 Apr 25.

Division of Hepatology, Liver Research Unit, Department of Gastroenterology and Hepatology, Linkou Chang Gung Memorial Hospital, Chang Gung University, 5, Fu-Hsin St., Kwei-Shan, Taoyuan, Taiwan, 333.

Objectives: Radiofrequency ablation (RFA) of medium-sized (3-5 cm) hepatocellular carcinoma (HCC) is suboptimal. Switching monopolar RFA (SW-RFA) enlarges the ablative volume to better cover larger tumors. This study aims to compare the long-term outcomes of medium-sized HCC treated by either SW-RFA or single-monopolar RFA (S-RFA). Read More

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Determination of initial airtightness after anatomical laser segmentectomy in an ex vivo model.

Lasers Med Sci 2021 Apr 23. Epub 2021 Apr 23.

Department of Surgery, Asklepios Stadtklinik Bad Wildungen, Bad Wildungen, Germany.

If a pulmonary pathology can be removed by anatomical segmentectomy, the need for lobectomy is obviated. The procedure is considered oncologically equivalent and saves healthy lung tissue. In every segmentectomy, lung parenchyma must be transected in the intersegmental plane. Read More

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Comparison of wire and disc electrodes to electrically activate the inspiratory muscles in dogs.

J Neurosci Methods 2021 Jun 2;357:109176. Epub 2021 Apr 2.

Department of Physical Medicine and Rehabilitation, Case Western Reserve University, 2500 MetroHealth Drive, Cleveland, OH, USA; MetroHealth Research Institute, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, OH, USA. Electronic address:

Objective: To compare the effectiveness of wire versus disc electrodes to activate the inspiratory muscles via high frequency spinal cord stimulation.

Design: Animal study.

Setting: Research laboratory. Read More

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Validation of Ultrasonic Harmonic Scalpel for Real-Time Tissue Identification Using Rapid Evaporative Ionization Mass Spectrometry.

Anal Chem 2021 04 31;93(14):5906-5916. Epub 2021 Mar 31.

Department of Metabolism, Digestion and Reproduction, Imperial College London, South Kensington Campus, London SW7 2AZ, United Kingdom.

In this study, we integrate rapid evaporative ionization mass spectrometry (REIMS) with the Harmonic scalpel, an advanced laparoscopic surgical instrument that utilizes ultrasound energy to dissect and coagulate tissues. It provides unparalleled manipulation capability to surgeons and has superseded traditional electrosurgical tools particularly in abdominal surgery, but is yet to be validated with REIMS. The REIMS platform coupled with the Harmonic device was shown to produce tissue-specific lipid profiles through the analysis of porcine tissues in both negative and positive ionization modes. Read More

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En-bloc resection of urinary bladder tumour - a prospective controlled multicentre observational study.

Wideochir Inne Tech Maloinwazyjne 2021 Mar 15;16(1):145-150. Epub 2020 May 15.

Second Department of Urology, Centre of Postgraduate Medical Education, Warsaw, Poland.

Introduction: Transurethral resection of bladder tumour (TURBT) is one of the most commonly performed urologic procedures. Because of the shortcomings of conventional TURBT, the en-bloc resection concept was created.

Aim: To analyse the influence of en-bloc technique on surgical and oncological outcomes of TURBT performed with electric current. Read More

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Computational exploration of epidural cortical stimulation using a realistic head model.

Comput Biol Med 2021 Mar 25:104290. Epub 2021 Mar 25.

School of Electrical Engineering and Computer Science, Gwangju Institute of Science & Technology, South Korea. Electronic address:

Motor cortex stimulation, either non-invasively or with implanted electrodes, has been applied worldwide as a treatment for intractable neuropathic pain syndromes. Although computer simulations of non-invasive brain stimulation have been investigated largely to optimize protocols and improve our understanding of underlying mechanisms using a realistic head model, computational studies of invasive cortical stimulation are rare and limited to very simplified cortical models. In this paper, we present an anatomically realistic head model for epidural cortical stimulation that includes the most sophisticated epidural electrodes with an insulating paddle. Read More

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Energy devices safety and impact on video-assisted thoracoscopic lung lobectomy postoperative course: monopolar electrocautery versus ultrasonic dissector.

J Cardiothorac Surg 2021 Mar 20;16(1):40. Epub 2021 Mar 20.

Center for Thoracic Surgery and Center for Minimally Invasive Surgery, Department of Medicine and Surgery, University of Insubria, Via Guicciardini 9, 21100, Varese, Italy.

Background: This study aims to compare safety and impact of monopolar electrocautery and ultrasonic dissector (Harmonic ACE Plus®) on postoperative short-term outcomes after video-assisted thoracoscopic (VATS) lobectomy and lymphadenectomy for lung cancer.

Methods: We analyzed the prospectively collected data of 140 consecutive patients [59% male; median age: 71(IQR:62-76) years] undergoing VATS lobectomy and lymphadenectomy in our institution between October 2016 and November 2019. Patients were divided in two groups based on device used: monopolar electric hook in 79 cases (Group A); ultrasonic dissector in 61(Group B). Read More

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Motion-insensitive diffusion imaging of the brain using optical tracking and dynamic sequence updates.

Magn Reson Med 2021 Aug 15;86(2):926-934. Epub 2021 Mar 15.

Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland, Baltimore, MD, USA.

Purpose: Diffusion-weighted imaging (DWI) is sensitive to head movements, which may cause signal losses because of motion-induced gradient imbalances. Prospective motion correction using fast optical tracking can attenuate these artifacts. Approaches include quasicontinuous updates of gradients and radiofrequency (RF) pulses or dynamically applying a rebalancing gradient to restore the gradient balance, but these prior methods used bipolar diffusion gradients. Read More

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Switching Monopolar No-Touch Radiofrequency Ablation Using Octopus Electrodes for Small Hepatocellular Carcinoma: A Randomized Clinical Trial.

Liver Cancer 2021 Feb 8;10(1):72-81. Epub 2020 Dec 8.

Department of Radiology, Seoul National University Hospital, Seoul, Republic of Korea.

Introduction: A switching monopolar no-touch radiofrequency ablation (RFA) technique is used for small hepatocellular carcinoma (HCC); however, there have not been any randomized clinical trials comparing this technique to the conventional RFA technique.

Objective: This study aims to compare the results of two RFA techniques, and to comparatively identify more effective methods to reduce the progression of local tumors associated with small HCC (≤2.5 cm). Read More

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February 2021

Short-term effects of 448 kilohertz radiofrequency stimulation on supraspinatus tendon elasticity measured by quantitative ultrasound elastography in professional badminton players: a double-blinded randomized clinical trial.

Int J Hyperthermia 2021 ;38(1):421-427

Clinica Ana Gonzalez, Malaga, Spain.

Objective: To study changes in supraspinatus tendon elasticity after a 448 kHz capacitive resistive monopolar radiofrequency (CRMR) intervention in professional badminton players.

Design: Double-blinded randomized clinical trial.

Setting: All participants were recruited in a private care practice. Read More

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January 2021

Ligasure™ Impact and Ligasure™ Small Jaw in Body Contouring after Massive Weight Loss: A New Perspective.

J Invest Surg 2021 Mar 10:1-8. Epub 2021 Mar 10.

Division of Plastic and Reconstructive Surgery; Department of Medicine, Surgery and Neuroscience, "Santa Maria alle Scotte" Hospital, University of Siena, Italy.

Background: The most effective dissection technique for elevating flaps in body contouring is still controversial, particularly in high-risk massive weight loss (MWL) patients. LigaSure (Medtronic, Dublin, Ireland) is an energy device commonly used among different surgical specialties to reduce morbidity and improve outcomes. The aim of this study is to investigate the effectiveness of LigaSure Impact and LigaSure Small Jaw in body contouring after MWL compared with conventional technique. Read More

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TTK inhibitor promotes radiosensitivity of liver cancer cells through p21.

Biochem Biophys Res Commun 2021 Apr 6;550:84-91. Epub 2021 Mar 6.

Graduate Department, Bengbu Medical College, Bengbu, Anhui, 233000, PR China; Department of Radiation Oncology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, 310014, PR China. Electronic address:

The monopolar spindle 1 ((hMps1/TTK) is a serine/threonine kinase that plays an important role in spindle assembly checkpoint signaling. To explore the possible relationship between TTK inhibition and radiosensitivity, we examined whether TTK inhibition influences cellular susceptibility of radiation. And we further revealed its mechanisms. Read More

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Thermal Conductance Through the Skull Base From Endoscopic Surgery Cauterization Instruments: Cadaver and Goat Model.

Otolaryngol Head Neck Surg 2021 Mar 9:1945998211000372. Epub 2021 Mar 9.

Tina and Rick Caruso Department of Otolaryngology-Head and Neck Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.

Objective: Cauterization prevents hemorrhage and optimizes the surgical field during endoscopic sinus surgery but may cause injury to nearby structures. The objective of this study is to examine thermal conductance from cauterization equipment across the skull base.

Study Design: Cadaver and animal model. Read More

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A Prospective Randomised Controlled Study Comparing Ultrasonic Dissector with Electrocautery for Axillary Dissection in Patients of Carcinoma Breast.

Malays J Med Sci 2021 Feb 24;28(1):97-104. Epub 2021 Feb 24.

Department of Surgery, Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital, New Delhi, India.

Background: Axillary dissection is one of the important components of modified radical mastectomy (MRM). The present study was conducted to compare surgical outcomes by using monopolar electrocautery and ultrasonic dissector for axillary dissection in MRM.

Methods: A parallel randomised controlled single blinded study was conducted with a sample size of 70 patients who were randomised into two groups. Read More

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February 2021

Monopolar electrocautery tip vs plasma ablation in tonsillotomy: A randomized case-control study comparing outcomes in pediatric population.

Int J Pediatr Otorhinolaryngol 2021 Apr 20;143:110655. Epub 2021 Feb 20.

Faculty of Medicine and Medical Sciences, Holy Spirit University of Kaslik (USEK), Jounieh, Lebanon; Department of Otolaryngology Head and Neck Surgery, Eye and Ear International Hospital, Naccache, Lebanon. Electronic address:

Background: The objective of this study was to compare the low-priced monopolar electrocautery to the high-priced, worldwide used, plasma ablation in tonsillotomy among children aged between three and twelve years, suffering from obstructive breathing disorders (OBD), with respect to post-operative pain, bleeding and related morbidities.

Methods: A randomized case-control study was conducted in the Eye and Ear Hospital International- Lebanon. 103 children aged between three and twelve years suffering from OBD secondary to tonsillar hypertrophy were randomly assigned into two groups. Read More

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Dimethoxycurcumin reduces proliferation and induces apoptosis in renal tumor cells more efficiently than demethoxycurcumin and curcumin.

Chem Biol Interact 2021 Apr 12;338:109410. Epub 2021 Feb 12.

Department of General Biology, Center of Biological Sciences, Londrina State University - UEL, Rodovia Celso Garcia Cid, Pr 445 Km 380, Londrina, Paraná, Brazil.

Curcumin (Cur), is a pigment with antiproliferative activity but has some pharmacokinetic limitations, which led researchers to look for more effective structure analogs. This work investigated the effects of Cur and compared them with the two analogs, demethoxycurcumin (DeMC) and dimethoxycurcumin (DiMC), to elucidate their mechanisms of action. The cytotoxic, antiproliferative, and genotoxic effects these compounds were correlated based on gene expression analysis in the human renal adenocarcinoma cells (786-O). Read More

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Efficacy and safety of bipolar versus monopolar transurethral resection of bladder tumors: A meta-analysis of randomized controlled trials.

J Cancer Res Ther 2020 ;16(7):1588-1595

First College of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi; Department of Urology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital and Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, Guangdong, China.

Context: In the management of bladder tumors bipolarenergy has been used as a common alternative to the conventional monopolar transurethral resection of the bladder (M-TURB).

Aim: This study aims to examine the clinical efficacy and safety of bipolar versus monopolar TURB tumors (TURBTs).

Subjects And Methods: We conducted a systematic literature search in the PubMed, Cochrane Library, and Embase databases for the identification of prospective randomized controlled trials (RCTs) that compared the outcomes between the two procedures. Read More

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January 2020

Modifications in the Topological Structure of EEG Functional Connectivity Networks during Listening Tonal and Atonal Concert Music in Musicians and Non-Musicians.

Brain Sci 2021 Jan 26;11(2). Epub 2021 Jan 26.

Departamento de Ciencias Médicas Básicas, Fisiología (Medicina), Universidad de La Laguna, 38200 Tenerife, Spain.

The present work aims to demonstrate the hypothesis that atonal music modifies the topological structure of electroencephalographic (EEG) connectivity networks in relation to tonal music. To this, EEG monopolar records were taken in musicians and non-musicians while listening to tonal, atonal, and pink noise sound excerpts. EEG functional connectivities (FC) among channels assessed by a phase synchronization index previously thresholded using surrogate data test were computed. Read More

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January 2021

Long-term outcome and survival rate of monopolar radial head replacement.

J Shoulder Elbow Surg 2021 Jan 20. Epub 2021 Jan 20.

Clinic for Trauma and Orthopaedic Surgery, BG Trauma Center Ludwigshafen, University of Heidelberg, Ludwigshafen on the Rhine, Germany. Electronic address:

Background: The purposes of this study were (1) to report functional outcomes; (2) to assess complications, revisions, and survival rate; and (3) to assess differences in functional outcomes between removed and retained radial head arthroplasties (RHAs), early and delayed treatment, and type of RHA used at long-term follow-up after monopolar RHA for unreconstructible radial head fractures or their sequelae.

Methods: Seventy-eight patients (mean age, 59.2 years) who were at least 6 years postoperatively after monopolar RHA for unreconstructible RHFs or their sequelae were included. Read More

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January 2021

Phase Lag Analyses on Ictal Scalp Electroencephalography May Predict Outcomes of Corpus Callosotomy for Epileptic Spasms.

Front Neurol 2020 15;11:576087. Epub 2020 Dec 15.

Comprehensive Epilepsy Center, Seirei-Hamamatsu General Hospital, Hamamatsu, Japan.

We aimed to clarify the patterns of ictal power and phase lag among bilateral hemispheres on scalp electroencephalography (EEG) recorded pre-operatively during epileptic spasms (ESs) and the correlation with the outcomes following corpus callosotomy. We enrolled 17 patients who underwent corpus callosotomy for ESs before 20 years of age. After corpus callosotomy, seven patients did not experience further ESs (favorable outcome group), and the remaining 10 patients had ongoing ESs (unfavorable outcome group). Read More

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December 2020

Piloting the recording of electrode voltages (REVS) using surface electrodes as a test to identify cochlear implant electrode migration, extra-cochlear electrodes and basal electrodes causing discomfort.

Cochlear Implants Int 2021 May 6;22(3):157-169. Epub 2021 Jan 6.

Faculty of Engineering and Physical Sciences, University of Southampton, SO17 1BJ Southampton, UK.

Objectives: To determine if Electrode Voltage (EV) measurements are potentially suitable as a test for detecting extra-cochlear electrodes in cochlear implants (CIs).

Methods: EV measurements were made using surface electrodes in live mode in 17 adult cochlear implant (CI) users. Repeatability, the effects of stimulation level, CI active electrode position, (active) recording electrode position and stimulation mode (for Nucleus devices) were investigated. Read More

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The impact of post-procedural ureteric stent duration on the outcome of retrograde endopyelotomy for management of failed open pyeloplasty in children: a preliminary report.

Med J Islam Repub Iran 2020 25;34:105. Epub 2020 Aug 25.

Department of Biostatics, Shiraz University of Medical Science, Shiraz, Iran.

To evaluate the outcome of retrograde endopyelotomy as a minimally invasive option for management of failed open pyeloplasty in children and assess how the duration of post-procedural stenting may affect the endopyelotomy outcome. A total of 15 patients with secondary UPJO (Ureteropelvic junction obstruction) underwent retrograde endopyelotomy. The procedure was done using low-energy monopolar electrocautery hook under direct vision of pediatric ureteroscope and control of fluoroscopy. Read More

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Chronic BACE-1 Inhibitor Administration in TASTPM Mice (APP KM670/671NL and PSEN1 M146V Mutation): An EEG Study.

Int J Mol Sci 2020 Nov 28;21(23). Epub 2020 Nov 28.

Department of Physiology and Pharmacology "V Erspamer", Sapienza University of Rome, 00185 Rome, Italy.

Objective: In this exploratory study, we tested whether electroencephalographic (EEG) rhythms may reflect the effects of a chronic administration (4 weeks) of an anti-amyloid β-site amyloid precursor protein (APP) cleaving enzyme 1 inhibitor (BACE-1; ER-901356; Eisai Co., Ltd., Tokyo, Japan) in TASTPM (double mutation in APP KM670/671NL and PSEN1 M146V) producing Alzheimer's disease (AD) amyloid neuropathology as compared to wild type (WT) mice. Read More

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November 2020

Radiofrequency ablation of the centromedian thalamic nucleus in the treatment of drug-resistant epilepsy.

Epilepsy Behav 2021 01 24;114(Pt A):107560. Epub 2020 Nov 24.

Unit for Stereotactic and Functional Neurosurgery, General Hospital of Mexico, Dr. Balmis 148 Col. Doctores Cuahutémoc, C.P. 06720 Mexico City, Mexico. Electronic address:

Objective: To determine the usefulness and efficacy of radiofrequency ablations (RFA) of the Centromedian thalamic nucleus (CMN) to control primarily generalized or multifocal seizures in refractory epilepsy.

Methods: Six patients with clinical diagnosis of multifocal or primarily generalized drug-resistant epilepsy were included. Bilateral RFA of the CMN was performed through a monopolar 1. Read More

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January 2021

Safety and Efficacy of Bipolar Transurethral Resection of the Prostate Monopolar Transurethral Resection of Prostate in the Treatment of Moderate-Large Volume Prostatic Hyperplasia: A Systematic Review and Meta-Analysis.

J Endourol 2020 Dec 28. Epub 2020 Dec 28.

Department of Urology, Sandwell and West Birmingham NHS Trust, Birmingham, United Kingdom.

To compare outcomes of monopolar bipolar transurethral resection of the prostate (TURP) in the management of exclusively moderate-large volume prostatic hyperplasia in terms of maximum flow rate as a surrogate for clinical efficacy, duration of catheterization, hospital stay, operative time, resection weight, transurethral resection (TUR) syndrome, acute urinary retention (AUR), clot retention, and blood transfusion. We conducted a search of electronic databases (PubMed, MEDLINE, EMBASE, CINAHL, and CENTRAL), identifying studies comparing the outcomes of monopolar and bipolar TURP in the management of large-volume prostatic hyperplasia. The Cochrane risk-of-bias tool for randomized controlled trials (RCTs) and the Newcastle-Ottawa scale for observational studies were used to assess included studies. Read More

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December 2020