18,467 results match your criteria comorbid psychiatric


Provisional posttraumatic stress disorder is associated with greater severity of eating disorder and comorbid symptoms in adolescents treated in residential care.

Eur Eat Disord Rev 2021 Sep 14. Epub 2021 Sep 14.

Monte Nido and Affiliates, Miami, Florida, USA.

Objective: Past traumatic events, subsequent posttraumatic stress disorder (PTSD) and related psychiatric comorbidities are commonly associated with eating disorders (EDs) in adults but remain understudied in adolescents.

Methods: Adolescent participants (mean [SD] age = 15.1 ± 1. Read More

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September 2021

Pharmacotherapy for alcohol use disorders - Unequal provision across sociodemographic factors and co-morbid conditions. A cohort study of the total population in Sweden.

Drug Alcohol Depend 2021 Aug 26:108964. Epub 2021 Aug 26.

Department of Global Public Health, Karolinska Institutet, 171 77, Stockholm, Sweden.

Background: Pharmacotherapy for alcohol use disorders (AUD) is effective. However, knowledge about utilization of, and patient characteristics associated with prescriptions is scarce. The aim is to investigate prescriptions of pharmacotherapy for AUD in Sweden across time, sociodemographics, domicile and comorbid conditions. Read More

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Association Between Comorbid Depression and Rates of Postoperative Complications, Readmissions, and Revision Arthroscopic Procedures After Elective Hip Arthroscopy.

Orthop J Sports Med 2021 Sep 7;9(9):23259671211036493. Epub 2021 Sep 7.

Department of Orthopedic Surgery, University of California-San Francisco, San Francisco, California, USA.

Background: Depression and related psychiatric diagnoses are common in patients undergoing hip arthroscopy for femoroacetabular impingement syndrome (FAIS). The effects of depression on postoperative complications, readmissions, and additional ipsilateral hip surgery are not well studied.

Hypothesis: Patients with preoperative depression who undergo hip arthroscopy for FAIS would experience higher rates of 90-day postoperative complications and readmissions, with an increased risk of additional ipsilateral hip procedures, as compared with patients without depression. Read More

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September 2021

The Association Between Internet Addiction and Anxiety in Nursing Students: A Network Analysis.

Front Psychiatry 2021 25;12:723355. Epub 2021 Aug 25.

Unit of Psychiatry, Department of Public Health and Medicinal Administration, & Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macao, Macao, SAR China.

Nursing students who suffer from co-occurring anxiety experience added difficulties when communicating and interacting with others in a healthy, positive, and meaningful way. Previous studies have found strong positive correlations between Internet addiction (IA) and anxiety, suggesting that nursing students who report severe IA are susceptible to debilitating anxiety as well. To date, however, network analysis (NA) studies exploring the nature of association between individual symptoms of IA and anxiety have not been published. Read More

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TNF-Alpha as an Initiator of Allodynia and Anxiety-Like Behaviors in a Preclinical Model of PTSD and Comorbid Pain.

Front Psychiatry 2021 25;12:721999. Epub 2021 Aug 25.

Department of Pharmaceutical Sciences, University of Oklahoma College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States.

Post-Traumatic Stress Disorder (PTSD) is a debilitating mental health disorder that occurs after exposure to a traumatic event. Patients with comorbid chronic pain experience affective distress, worse quality of life, and poorer responses to treatments for pain or PTSD than those with either condition alone. FDA-approved PTSD treatments are often ineffective analgesics, requiring additional drugs to treat co-morbid symptoms. Read More

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Comorbid Premenstrual Dysphoric Disorder and Bipolar Disorder: A Review.

Front Psychiatry 2021 25;12:719241. Epub 2021 Aug 25.

Women's Health Concerns Clinic and Mood Disorders Treatment and Research Centre, St Joseph's Healthcare Hamilton, Hamilton, ON, Canada.

Bipolar disorder (BD) differs in its clinical presentation in females compared to males. A number of clinical characteristics have been associated with BD in females: more rapid cycling and mixed features; higher number of depressive episodes; and a higher prevalence of BD type II. There is a strong link between BD and risk for postpartum mood episodes, and a substantial percentage of females with BD experience premenstrual mood worsening of varying degrees of severity. Read More

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Somatization Symptoms Regulate Emotional Memory Bias in Adolescents With Major Depressive Disorder.

Front Psychiatry 2021 26;12:656198. Epub 2021 Aug 26.

Department of Psychiatry, Affiliated Psychological Hospital of Anhui Medical University, Hefei, China.

Somatization symptoms are commonly comorbid with depression. Furthermore, people with depression and somatization have a negative memory bias. We investigated the differences in emotional memory among adolescent patients with depressive disorders, with and without functional somatization symptoms (FSS). Read More

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Association of Systemic Inflammation with Depressive Symptoms in Individuals with COPD.

Int J Chron Obstruct Pulmon Dis 2021 3;16:2515-2522. Epub 2021 Sep 3.

University of Pittsburgh Medical Center, Department of Medicine, Department of Pulmonary Allergy and Critical Care Medicine, Pittsburgh, PA, USA.

Rationale: Depression is a prevalent comorbidity of chronic obstructive pulmonary disease (COPD) that, along with COPD, has been associated with inflammation. An association between inflammation and depression in COPD has not been validated in a large COPD cohort.

Methods: Individuals from the University of Pittsburgh SCCOR cohort and the COPDGene cohort with tobacco use history and airway obstruction (FEV/FVC <0. Read More

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September 2021

A multinational case-control study comparing forensic and non-forensic patients with schizophrenia spectrum disorders: the EU-VIORMED project.

Psychol Med 2021 Sep 13:1-11. Epub 2021 Sep 13.

Unit of Statistics, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.

Background: The relationship between schizophrenia and violence is complex. The aim of this multicentre case-control study was to examine and compare the characteristics of a group of forensic psychiatric patients with a schizophrenia spectrum disorders and a history of significant interpersonal violence to a group of patients with the same diagnosis but no lifetime history of interpersonal violence.

Method: Overall, 398 patients (221 forensic and 177 non-forensic patients) were recruited across five European Countries (Italy, Germany, Poland, Austria and the United Kingdom) and assessed using a multidimensional standardised process. Read More

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September 2021

Basal and LPS-stimulated inflammatory markers and the course of anxiety symptoms.

Brain Behav Immun 2021 Sep 9. Epub 2021 Sep 9.

Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands.

A cross-sectional relationship between low-grade inflammation -characterized by increased blood levels of C-reactive protein (CRP) and pro-inflammatory cytokines- and anxiety has been reported, but the potential longitudinal relationship has been less well studied. We aimed to examine whether basal and lipopolysaccharide (LPS-)induced levels of inflammatory markers are associated with anxiety symptom severity over the course of nine years. We tested the association between basal and LPS-induced inflammatory markers with anxiety symptoms (measured with the Beck's Anxiety Inventory; BAI, Fear Questionnaire;FQ and Penn's State Worry Questionnaire; PSWQ) at 5 assessment waves over a period up nine years. Read More

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September 2021

Depression in Patients with Alcohol Dependence Syndrome in a Tertiary Care Center: A Descriptive Cross-sectional Study.

Authors:
Mukti Acharya

JNMA J Nepal Med Assoc 2021 Aug 12;59(240):787-790. Epub 2021 Aug 12.

Department of Psychiatry, Nobel Medical College and Teaching Hospital, Biratnagar, Nepal.

Introduction: Alcohol dependence syndrome is an important and major public health issue seen in our community and health center. It is mostly associated with different mental health problems and psychiatric co-morbidities. This study aims to find out the prevalence of depression among alcohol dependence syndrome in a tertiary care hospital. Read More

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Cortical thickness predicts remission of depression with antidepressants in patients with late-life depression and cognitive impairment.

J Affect Disord 2021 Aug 29;295:438-445. Epub 2021 Aug 29.

Department of Psychiatry, Division of Geriatric Psychiatry, Columbia University and the New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, United States.

Background: Depression (DEP) and cognitive impairment (CI) share etiological risk factors, anatomical underpinnings, and interact to produce deleterious treatment outcomes. Both DEP and CI exhibit altered patterns of cortical thickness which may impact the course of antidepressant treatment, though inconsistencies in directionality and affected brain regions have been reported. In this study, we examined the relationship between cortical thickness and treatment outcome in older adults with comorbid DEP-CI. Read More

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Personality Disorders among Patients with Mental and Behavioral Disorders due to Psychoactive Substance Use in a Tertiary Care Center of Nepal: A Descriptive Cross-sectional Study.

JNMA J Nepal Med Assoc 2021 Feb 28;59(234):184-187. Epub 2021 Feb 28.

Department of Psychiatry, Shree Birendra Hospital, Chhauni, Kathmandu, Nepal.

Introduction: Personality disorders is comprised of deeply ingrained and enduring behavioral patterns, manifesting themselves as inflexible responses to a broad range of personal and social situations." Personality Disorders are frequently occurring among patients with substance use disorders. Co-occurrence of substance use disorders and personality disorder is associated with a greater functional impairment affecting treatment adherence. Read More

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February 2021

Efficacy and acceptability of pharmacotherapy for comorbid anxiety symptoms in bipolar disorder: A systematic review and meta-analysis.

Bipolar Disord 2021 Sep 10. Epub 2021 Sep 10.

Centre for Addiction and Mental Health, Toronto, ON, Canada.

Objective: Anxiety symptoms are highly prevalent among individuals with bipolar disorder (BD) but there is little guidance on pharmacotherapy for these symptoms. The objective of this systematic review and meta-analysis was to evaluate the available evidence for pharmacotherapy of comorbid anxiety symptoms in BD.

Methods: Completed randomized clinical trials (RCTs) of medications for BD published prior to December 2020 were identified through a systematic search of MEDLINE, Embase, PsycInfo, Web of Science, clinicaltrials. Read More

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September 2021

The clinical characterization of the adult patient with an anxiety or related disorder aimed at personalization of management.

World Psychiatry 2021 Oct;20(3):336-356

Department of Psychiatry, University of Campania "L. Vanvitelli", Naples, Italy.

The clinical construct of "anxiety neurosis" was broad and poorly defined, so that the delineation of specific anxiety disorders in the DSM-III was an important advance. However, anxiety and related disorders are not only frequently comorbid, but each is also quite heterogeneous; thus diagnostic manuals provide only a first step towards formulating a management plan, and the development of additional decision support tools for the treatment of anxiety conditions is needed. This paper aims to describe systematically important domains that are relevant to the personalization of management of anxiety and related disorders in adults. Read More

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October 2021

Treatment of Adolescents with Concurrent Substance Use Disorder and Attention-Deficit/Hyperactivity Disorder: A Systematic Review.

J Clin Med 2021 Aug 30;10(17). Epub 2021 Aug 30.

Parnassia Addiction Research Centre (PARC), Parnassia Psychiatric Institute, 2512 HN The Hague, The Netherlands.

Childhood attention-deficit/hyperactivity disorder (ADHD) is a risk factor for the development of substance abuse and substance use disorders (SUD) in adolescence and (early) adulthood. ADHD and SUD also frequently co-occur in treatment-seeking adolescents, which complicates diagnosis and treatment, and is associated with poor treatment outcomes. In this study, we provide a systematic review of controlled studies on the effectiveness of pharmacological, psychosocial, and complementary treatments of ADHD in adolescents with and without comorbid SUD. Read More

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Binge drinking following residential treatment for posttraumatic stress disorder among veterans with and without alcohol use disorder.

J Psychiatr Res 2021 Sep 3;143:202-208. Epub 2021 Sep 3.

VA Connecticut Healthcare System, 950 Campbell Avenue, Psychology Service/Department of Psychiatry, 116A, West Haven, CT, 06516, USA; Yale University School of Medicine, Department of Psychiatry, USA.

Posttraumatic stress disorder (PTSD) is complicated by high rates of problematic drinking and comorbid alcohol use disorder (AUD). This study examined veterans seeking residential PTSD treatment, comparing those with and without AUD, to determine whether trauma type and/or PTSD symptom changes during treatment were associated with binge drinking at 4-month follow-up. Analyses compared characteristics of veterans (N = 758) in residential treatment, as well as associations of demographic, trauma, and alcohol-related variables, with binge drinking episodes at follow-up. Read More

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September 2021

Risk factors of violent offending in mentally ill prisoners with autism spectrum disorders.

J Psychiatr Res 2021 Sep 2;143:183-188. Epub 2021 Sep 2.

Department of Criminal Law and Criminology, Vrije Universiteit Amsterdam, the Netherlands.

Background: Results of research regarding a possible causal relation between autism spectrum disorders (ASDs) and violence are mixed. Several explanations have been proposed.

Aims: To assess prevalence rates of comorbid disorders in a large sample of mentally ill offenders diagnosed with ASD. Read More

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September 2021

Improving linkage and retention in treatment among people living with HIV and comorbid substance use.

AIDS Care 2021 Sep 9:1-6. Epub 2021 Sep 9.

Department of Psychiatry, The University of Texas Dell Medical School, Austin, TX, USA.

HIV and substance use interact synergistically to exacerbate disease progression and contribute to poorer engagement in treatment. There is a lack of qualitative research exploring the complexity of systems that impact HIV patients' linkage to and retention in both substance use and HIV care. Data from qualitative individual interviews with 16 HIV and 13 substance use providers were analyzed using applied thematic analysis. Read More

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September 2021

Male-female ratios in autism spectrum disorders by age, intellectual disability and attention deficit/hyperactivity disorder.

Acta Psychiatr Scand 2021 Sep 8. Epub 2021 Sep 8.

Department of Global Public Health and Primary Care, University of Bergen, Norway.

Objective: To examine the gender distribution in ASD in adults compared to children, and the impact of comorbid intellectual disability (ID) and attention deficit/hyperactivity disorder (ADHD) on the male to female ratio (MFR).

Methods: We estimated the MFR and the male prevalence ratio (PR) for ASD in adults and children using the Medical Birth Registry of Norway, including all individuals born 1967-2011. We examined variation with age, comorbid ID and ADHD as defined by diagnoses in the Norwegian Patient Registry during 2008-2015 and/or a dispensed prescription for ADHD medication. Read More

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September 2021

Interstitial cystitis/bladder pain syndrome patient is associated with subsequent increased risks of outpatient visits and hospitalizations: A population-based study.

PLoS One 2021 7;16(9):e0256800. Epub 2021 Sep 7.

Division of Urogynecology, Department of Obstetrics and Gynecology, Chi Mei Medical Center, Tainan, Taiwan.

Interstitial cystitis/bladder pain syndrome (IC/BPS) is not only a chronic urinary bladder pain syndrome but is also associated with multifactorial etiology. Our study aimed to test the hypothesis that IC/BPS is associated with subsequent increased risks of outpatient visits and hospitalizations. Using nationwide database, the diagnoses were based on the International Classification Codes (ICD-9-CM) (595. Read More

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September 2021

Factors associated with dropout in the longitudinal Vogel Study of cognitive decline.

Eur J Neurosci 2021 Sep 7. Epub 2021 Sep 7.

Center for Mental Health, Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Würzburg, Würzburg, Germany.

Dementia, including Alzheimer's Disease (AD), is a growing problem worldwide. Prevention or early detection of the disease or a prodromal cognitive decline is necessary. By means of our long-term follow-up "Vogel Study", we aim to predict the pathological cognitive decline of a German cohort (mean age was 73. Read More

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September 2021

Problematic Opioid Use Among Older Adults: Epidemiology, Adverse Outcomes and Treatment Considerations.

Drugs Aging 2021 Sep 7. Epub 2021 Sep 7.

Department of Psychiatry and Behavioural Neurosciences, St. Joseph's Healthcare Hamilton, McMaster University, West 5th Campus, Administration-B3, 100 West 5th, Hamilton, ON, L8N 3K7, Canada.

With the aging population, an increasing number of older adults (> 65 years) will be affected by problematic opioid use and opioid use disorder (OUD), with both illicit and prescription opioids. Problematic opioid use is defined as the use of opioids resulting in social, medical or psychological consequences, whereas OUD is a form of problematic use that meets diagnostic criteria as defined by the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition. Problematic use of opioids by older adults is associated with a number of pertinent adverse effects, including sedation, cognitive impairment, falls, fractures and constipation. Read More

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September 2021

Khat Use Patterns, Associated Features, and Psychological Problems in a Khat-Treatment-Seeking Student Sample of Jimma University, Southwestern Ethiopia.

Front Public Health 2021 19;9:645980. Epub 2021 Aug 19.

Department of Psychology, University of Konstanz, Konstanz, Germany.

Khat () is a traditionally used substance in African and Arab countries that contains the amphetamine-like alkaloid cathinone. Khat use among Ethiopian students is a growing concern. This study aims to describe khat use, psychological problems, and motivation to change and to determine associated factors of khat use among students from Jimma University seeking psychological assistance. Read More

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Does Concentrated Exposure Treatment for Obsessive-Compulsive Disorder Improve Insomnia Symptoms? Results From a Randomized Controlled Trial.

Front Psychiatry 2021 19;12:625631. Epub 2021 Aug 19.

Bergen Center for Brain Plasticity, Haukeland University Hospital, Bergen, Norway.

Insomnia is a substantial problem in patients with obsessive-compulsive disorder (OCD). There is, however, a lack of studies investigating changes in concurrent symptoms of insomnia in OCD after concentrated treatment. A recent randomized controlled trial randomized participants to the Bergen 4-day treatment (B4DT, = 16), or 12 weeks of unguided self-help (SH, = 16), or waitlist (WL, = 16). Read More

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Hearing Rehabilitative Treatment for Older Adults With Comorbid Hearing Loss and Depression: Effects on Depressive Symptoms and Executive Function.

Am J Geriatr Psychiatry 2021 Aug 14. Epub 2021 Aug 14.

New York State Psychiatric Institute (XH, PJB, YL, SPR, BRR), Columbia University Vagelos College of Physicians and Surgeons, New York, NY.

Objectives: Recent research has revealed important neural and psychiatric consequences of hearing loss (HL) in older adults. This pilot study examined the neural effects of HL and the impact of hearing aids on neuropsychiatric outcomes in major depressive disorder (MDD).

Design: Twelve-week, double-blind, randomized controlled trial. Read More

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The mediating role of self-compassion in the relationship between positive reactivity, negative reactivity, and perfectionism with disordered eating.

J Educ Health Promot 2021 30;10:249. Epub 2021 Jul 30.

Department of Psychiatry, School of Medicine, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Background: Individuals with disordered eating are at an increased of having one or more additional risks for comorbid disorders, such as anxiety disorder, depressive disorder, and insomnia. Therefore, the present study aimed to investigate the mediating role of self-compassion in the relationship between positive reactivity, negative reactivity, and perfectionism with disordered eating.

Materials And Methods: The study method was descriptive-correlational through structural equation modeling (SEM). Read More

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