10,986 results match your criteria comorbid mental

Review: Adult Outcome as Seen Through Controlled Prospective Follow-up Studies of Children With Attention-Deficit/Hyperactivity Disorder Followed Into Adulthood.

J Am Acad Child Adolesc Psychiatry 2021 Jun 5. Epub 2021 Jun 5.

McGill University Health Center, Montreal, Quebec, Canada; Division of Child Psychiatry, McGill University, Montreal Children's Hospital, McGill University Health Center, Montreal, Quebec, Canada. Electronic address:

Objective: To describe adult outcome of people with childhood diagnosed attention-deficit/hyperactivity disorder (ADHD) and its several key predictors via a review of seven North American controlled prospective follow-up studies: the Montreal, New York, Milwaukee, Pittsburgh, Massachusetts General Hospital (MGH), Berkeley and the seven-site Multimodal Treatment Study of Children with ADHD (MTA).

Method: All studies were prospective and followed children diagnosed with ADHD and an age and gender-matched control group at regular intervals from childhood (6-12 years) through adolescence into adulthood (20-40 years), evaluating symptom and syndrome persistence, functional outcomes and predictors of these outcomes.

Results: The rates of the ADHD syndrome persistence ranged from 5. Read More

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Impact of Parental Impulsivity on Attention Deficit Hyperactivity Disorder and Oppositional Defiant Disorder: Do Mothers' Attitudes Predict Symptom Severity in Children?

J Nerv Ment Dis 2021 Jun 11. Epub 2021 Jun 11.

Department of Child and Adolescent Psychiatry, Balıkesir Atatürk Research and Training Hospital, Balıkesir Department of Child and Adolescent Psychiatry, University of Health Sciences, Dr Sami Ulus Maternity and Children's Research and Training Hospital, Ankara Department of Psychiatry, Balıkesir Atatürk Research and Training Hospital, Balıkesir Department of Child and Adolescent Psychiatry, Aksaray University Research and Training Hospital, Aksaray Department of Child And Adolescent Psychiatry, University of Health Sciences, Ankara Research and Training Hospital Department of Child and Adolescent Psychiatry, University of Health Sciences, Gulhane Training and Research Hospital, Ankara, Turkey.

Abstract: Attention deficit hyperactivity disorder (ADHD) is a chronic neurodevelopmental disorder that occurs early in school-aged children, and it is highly comorbid with oppositional defiant disorder (ODD). Parents of children with ADHD frequently show mental problems related to impulsivity. The aim of this study was to examine the relationship between impulsivity of the mothers and the symptom patterns and severity of children. Read More

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Stroke care and case fatality in people with and without schizophrenia: a retrospective cohort study.

BMJ Open 2021 Jun 10;11(6):e044766. Epub 2021 Jun 10.

Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

Background: Schizophrenia is associated with an increased risk of death following stroke; however, the magnitude and underlying reasons for this are not well understood.

Objective: To determine the association between schizophrenia and stroke case fatality, adjusting for baseline characteristics, stroke severity and processes of care.

Design: Retrospective cohort study used linked clinical and administrative databases. Read More

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Upper Limb Home-Based Robotic Rehabilitation During COVID-19 Outbreak.

Front Robot AI 2021 24;8:612834. Epub 2021 May 24.

Human in the Loop Systems Laboratory, Department of Mechanical and Aerospace Engineering, University at Buffalo, Buffalo, NY, United States.

The coronavirus disease (COVID-19) outbreak requires rapid reshaping of rehabilitation services to include patients recovering from severe COVID-19 with post-intensive care syndromes, which results in physical deconditioning and cognitive impairments, patients with comorbid conditions, and other patients requiring physical therapy during the outbreak with no or limited access to hospital and rehabilitation centers. Considering the access barriers to quality rehabilitation settings and services imposed by social distancing and stay-at-home orders, these patients can be benefited from providing access to affordable and good quality care through home-based rehabilitation. The success of such treatment will depend highly on the intensity of the therapy and effort invested by the patient. Read More

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The Utility of an Anxiety Screening Measure in Youth with Functional Abdominal Pain Disorders and Clinical Characteristics Associated with Presence of Anxiety.

Clin J Pain 2021 Jun 9. Epub 2021 Jun 9.

Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19107 Department of Family Medicine, Michigan State University, 15 Michigan Street NE, Grand Rapids, Michigan 49503.

Objectives: Anxiety is common in youth with functional abdominal pain disorders (FAPD) and is related to increased pain-related impairment. However, it is unknown if self-reported anxiety on a clinical screener represents a true anxiety disorder diagnosis in youth with FAPD. Further, little is known about clinical characteristics in youth with FAPD and comorbid anxiety (ANX). Read More

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Asthma and Posttraumatic Stress Disorder (PTSD): emerging links, potential models and mechanisms.

Brain Behav Immun 2021 Jun 6. Epub 2021 Jun 6.

Dept. of Pharmacology & Systems Physiology, University of Cincinnati, Cincinnati OH, 45220 USA; Neuroscience Graduate Program, University of Cincinnati, Cincinnati OH, 45220 USA; VA Medical Center, Cincinnati, OH, 45220 USA. Electronic address:

Posttraumatic stress disorder (PTSD) is a highly prevalent, debilitating mental health condition. A better understanding of contributory neurobiological mechanisms will lead to effective treatments, improving quality of life for patients. Given that not all trauma-exposed individuals develop PTSD, identification of pre-trauma susceptibility factors that can modulate posttraumatic outcomes is important. Read More

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Integrating Behavioral Health and Serious Illness Care in a Post-COVID-19 Environment.

Psychiatr Serv 2021 Jun 9:appips202000903. Epub 2021 Jun 9.

Division of Geriatrics and Palliative Medicine, Weill Department of Medicine, Weill Cornell Medicine, New York City (Shalev); Department of Medicine, Division of Palliative Medicine (Shalev), and Department of Psychiatry (Pincus), Columbia University, New York City; Division of Mental Health Services and Policy Research, New York State Psychiatric Institute, New York City (Spaeth-Rublee, Pincus); Department of Psychiatry, Division of Consultation-Liaison Psychiatry (Cheung, Levenson), Irving Institute for Clinical and Translational Research (Pincus), and Vagelos College of Physicians and Surgeons (Pincus), Columbia University Irving Medical Center, New York City. Benjamin G. Druss, M.D., M.P.H., and Gail Daumit, M.D., M.H.S., are editors of this column.

Individuals with serious medical illnesses experience high rates of comorbid behavioral health conditions. Behavioral health comorbidity affects outcomes in serious illness care. Despite this consequence, behavioral health remains siloed from serious illness care. Read More

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Long-term Follow-up Assessment of Opioid Use Outcomes among Individuals with Comorbid Mental Disorders and Opioid Use Disorder Treated with Buprenorphine or Methadone in a Randomized Clinical Trial.

Addiction 2021 Jun 9. Epub 2021 Jun 9.

Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington.

Aims: To investigate whether reduction in opioid use differs when treated by either buprenorphine-naloxone (BUP) or methadone (MET) among adults with comorbid opioid use disorder (OUD) and mental disorders.

Design, Setting, And Participants: In a randomized controlled trial, adults with OUD were randomized to 24 weeks of either BUP or MET treatment and followed up in three yearly assessments. The present secondary analyses were based on 597 participants who completed all assessments. Read More

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[What do we know about borderline personality disorder? Current aspects of etiology, diagnostics and treatment].

Nervenarzt 2021 Jun 8. Epub 2021 Jun 8.

Institut für Psychiatrische und Psychosomatische Psychotherapie, Lehrstuhl für Psychosomatische Medizin und Psychotherapie, Medizinische Fakultät Mannheim, Universität Heidelberg, Zentralinstitut für Seelische Gesundheit Mannheim, J 5, 68159, Mannheim, Deutschland.

Background: Borderline personality disorder (BPS) is considered as a severe mental disorder with a high burden for patients, family members and the healthcare system. Recent years have brought significant advances in understanding and treating BP, leading to an earlier diagnosis and better treatment outcomes.

Objective: This article outlines the current state of knowledge on the epidemiology, diagnostics, psychopathology and treatment of BPD and identifies open questions. Read More

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Association Between Prenatal Opioid Exposure and Neurodevelopmental Outcomes in Early Childhood: A Retrospective Cohort Study.

Drug Saf 2021 Jun 7. Epub 2021 Jun 7.

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, California, CA, USA.

Introduction: Several studies have reported increasing prevalence of prescription opioid use among pregnant women. However, little is known regarding the effects of maternal opioid use on neurodevelopmental disorders in early childhood in pregnant women with no evidence of opioid use disorders or drug dependence.

Objective: The aim of this study was to quantify the association between prenatal opioid exposure from maternal prescription use and neurodevelopmental outcomes in early childhood. Read More

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Factors Predicting Trial Engagement, Treatment Satisfaction, and Health-Related Quality of Life During a Web-Based Treatment and Social Networking Trial for Binge Drinking and Depression in Young Adults: Secondary Analysis of a Randomized Controlled Trial.

JMIR Ment Health 2021 Jun 7;8(6):e23986. Epub 2021 Jun 7.

Centre for Brain and Mental Health Research, School of Medicine and Public Health, The University of Newcastle, Callaghan, Australia.

Background: Mental health and alcohol use problems are among the most common causes of disease burden in young Australians, frequently co-occur (comorbidity), and lead to significant lifetime burden. However, comorbidities remain significantly underdetected and undertreated in health settings. Digital mental health tools designed to identify at-risk individuals, encourage help-seeking, or deliver treatment for comorbidity have the potential to address this service gap. Read More

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Chronic High Risk Prescription Opioid Use Among Persons With HIV.

Front Sociol 2021 18;6:645992. Epub 2021 May 18.

Icahn School of Medicine at Mount Sinai, Division of Infectious Diseases, NY, NY, United States.

Persons with HIV (PWH) are a population at risk for adverse sequelae of opioid use. Yet, few studies have examined correlates of chronic high risk opioid use and its impact on HIV outcomes. Trends in prescribing patterns and identification of factors that impact the use of opioid prescriptions among PWH are crucial to determine prevention and treatment interventions. Read More

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Healthcare Expenditures Associated With Comorbid Anxiety and Depression Among Adults With Migraine.

Front Neurol 2021 21;12:658697. Epub 2021 May 21.

Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

Depression and anxiety are common among patients with migraine and usually associated with a humanistic and financial burden. This study aims to examine the direct healthcare expenditures among adults with migraine alone or with comorbid anxiety and/or depression. This was a retrospective cross-sectional study using 2012, 2014, and 2016 Medical Expenditure Panel Survey data. Read More

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Rate of OCD and sub-threshold OCD in bipolar disorder patients with first depressive episode.

Psychiatry Res 2021 May 15;302:114010. Epub 2021 May 15.

Ma'ale HaCarmel Mental Health Center, Tirat Carmel, Israel; Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel. Electronic address:

Evidence indicates that obsessive-compulsive disorder (OCD) co-occurs with bipolar disorder (BD) at a higher rate than in the general population. Although there is a preliminary indication of a predominant aggregation of OCD in BD patients with bipolar depression (BP-D), no explicit evaluation has previously been undertaken. Using the Structured Clinical Interview for DSM-5 Axis-I disorders and appropriate rating scales, seventy-three BD patients experiencing their first depressive episode were screened for OCD and subthreshold OCD. Read More

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Baseline sleep quality moderates symptom improvement in veterans with comorbid PTSD and TBI receiving trauma-focused treatment.

Behav Res Ther 2021 May 29;143:103892. Epub 2021 May 29.

Psychology Service, VA San Diego Healthcare System, 3350 La Jolla Village Dr, San Diego, CA, 92161, USA; Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, 3350 La Jolla Village Dr, San Diego, CA, 92161, USA; Department of Psychiatry, University of California San Diego, 9500 Gilman Dr., San Diego, CA, 92093, USA. Electronic address:

Poor sleep quality is common among Veterans with posttraumatic stress disorder (PTSD) and history of traumatic brain injury (TBI). However, the relationship between sleep quality and treatment outcomes following trauma-focused interventions is less well-understood in this population. We sought to better understand whether 1) sleep quality changed as a result of trauma-focused treatment and 2) if baseline sleep quality moderated psychological and neurobehavioral treatment outcomes. Read More

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A lateralized model of the pain-depression dyad.

Neurosci Biobehav Rev 2021 Jun 6;127:876-883. Epub 2021 Jun 6.

Center for Pain and the Brain, Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Chronic pain and depression are two frequently co-occurring and debilitating conditions. Even though the former is treated as a physical affliction, and the latter as a mental illness, both disorders closely share neural substrates. Here, we review the association of pain with depression, especially when symptoms are lateralized on either side of the body. Read More

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Food addiction comorbid to mental disorders in adolescents: a nationwide survey and register-based study.

Eat Weight Disord 2021 Jun 5. Epub 2021 Jun 5.

Department of Affective Disorders, Aarhus University Hospital, Psychiatry, Aarhus, Denmark.

Purpose: Adolescence is a high-risk period for development of addictive behavior. This may also apply to addiction-like eating of highly processed foods-commonly referred to as "food addiction". Adolescents with mental disorder may be at particularly elevated risk of developing food addiction as addiction often accompanies mental disorder. Read More

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Depression, health comorbidities, cognitive symptoms and their functional impact: Not just a geriatric problem.

J Psychiatr Res 2021 Jul 7;139:185-192. Epub 2021 May 7.

Sierra Pacific Mental Illness Research Education and Clinical Centers (MIRECC), Veterans Affairs Palo Alto Health Care System, 3801 Miranda Ave, Palo Alto, CA, 94304, USA; Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Rd, Stanford, CA, 94305, USA; School of Psychology, University of Queensland, Brisbane, QLD, 4072, Australia.

Objective: To compare the prevalence of cognitive symptoms and their functional impact by age group accounting for depression and number of other health conditions.

Methods: We analyzed data from the 2011 Behavioral Risk Factor Surveillance System, a population-based, cross-sectional telephone survey of US adults. Twenty-one US states asked participants (n = 131, 273) about cognitive symptoms (worsening confusion or memory loss in the past year) and their functional impact (interference with activities and need for assistance). Read More

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Racial Differences in the Association Between Alcohol Drinking and Cigarette Smoking: Preliminary Findings From an Alcohol Research Program.

Alcohol Alcohol 2021 Jun 4. Epub 2021 Jun 4.

Clinical Psychoneuroendocrinology and Neuropsychopharmacology Section, Translational Addiction Medicine Branch, National Institute on Drug Abuse Intramural Research Program and National Institute on Alcohol Abuse and Alcoholism Division of Intramural Clinical and Biological Research, National Institutes of Health, Baltimore and Bethesda, MD 20892, USA.

Aims: Important differences have been shown in alcohol drinking and cigarette smoking prevalence, patterns and consequences among individuals from different racial backgrounds. Alcohol and nicotine are often co-used, and the association between drinking and smoking may differ between racial groups-a question explored in the present study.

Methods: Data from the NIAAA natural history and screening protocols were utilized; non-Hispanic Black and non-Hispanic White individuals were included in the analyses [N = 1692; 65. Read More

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Editorial Perspective: Psychosis risk in adolescence - outcomes, comorbidity, and antipsychotics.

J Child Psychol Psychiatry 2021 Jun 4. Epub 2021 Jun 4.

Department of Neuroscience, University of Turin, Turin, Italy.

Research on Clinical High-Risk for Psychosis (CHR-P) has led to a vigorous change in the field of early detection in psychiatry and is gradually expanding its focus toward early development. The Annual Research Review on psychosis risk in adolescents (Journal of Child Psychology and Psychiatry, 62, 2020 and 657) offers a wide-angle meta-analytical picture of such emerging trends in all areas relevant to CHR-P Research, that is, detection, prognosis, and intervention. This editorial perspective is meant to expand the clinical and conceptual reach of these meta-analytic findings in relation to (a) the influence of age on transition rate and scalability of the early detection model across the child-adolescent vs adult periods; (b) potential latent heterogeneity of the pathogenetic trajectories leading to CHR-P as suggested by comorbid psychopathologies; (c) controversial (or at least problematic) prognostic significance of antipsychotic exposure in CHR-P subjects, especially in children and adolescents. Read More

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Role of age, gender and marital status in prognosis for adults with depression: An individual patient data meta-analysis.

Epidemiol Psychiatr Sci 2021 Jun 4;30:e42. Epub 2021 Jun 4.

Research Department of Clinical, Educational & Health Psychology, Centre for Outcomes Research and Effectiveness (CORE), University College London, 1-19 Torrington Place, LondonWC1E 7HB, UK.

Aims: To determine whether age, gender and marital status are associated with prognosis for adults with depression who sought treatment in primary care.

Methods: Medline, Embase, PsycINFO and Cochrane Central were searched from inception to 1st December 2020 for randomised controlled trials (RCTs) of adults seeking treatment for depression from their general practitioners, that used the Revised Clinical Interview Schedule so that there was uniformity in the measurement of clinical prognostic factors, and that reported on age, gender and marital status. Individual participant data were gathered from all nine eligible RCTs (N = 4864). Read More

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Primary healthcare approach to substance abuse management.

Ramprakash Kaswa

S Afr Fam Pract (2004) 2021 May 26;63(1):e1-e4. Epub 2021 May 26.

Department of Family Medicine and Rural Health, Walter Sisulu University, Mthatha.

Substance abuse is common amongst patients attending primary healthcare settings. Despite the substantial impact on one's health, substance abuse is often underdiagnosed by primary care providers owing to a lack of training and time for screening. Self-reported screening tools are easy to administer and efficient to make a substance abuse diagnosis in primary care settings. Read More

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Chronic Care, Dementia Care Management, and Financial Considerations.

J Am Med Dir Assoc 2021 May 31. Epub 2021 May 31.

VA New York Harbor Healthcare System, New York, NY, USA; Division of Geriatrics and Palliative Care in the Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA; Department of Population Health, NYU Grossman School of Medicine, New York, NY, USA. Electronic address:

The needs of persons living with Alzheimer's disease and Alzheimer's disease-related dementia (AD/ADRD) are challenged by tremendous complexity impacting both care delivery and financing. Most persons living with dementia (PLWD) also suffer from other chronic medical or mental health conditions, which further burden quality of life and function. In addition to difficult treatment choices, optimal dementia care models likely involve people and services that are not typical pieces of the health care delivery system but are all critical partners-care partners, social workers, and community services, to name a few. Read More

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Effects of Treatment Setting on Outcomes of Flexibly-Dosed Intensive Cognitive Behavioral Therapy for Pediatric OCD: A Randomized Controlled Pilot Trial.

Front Psychiatry 2021 17;12:669494. Epub 2021 May 17.

British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.

Optimizing individual outcomes of cognitive-behavioral therapy (CBT) remains a priority. Youth were randomized to receive intensive CBT at a hospital clinic ( = 14) or within their home ( = 12). Youth completed 3 × 3 h sessions (Phase I) and up to four additional 3-h sessions as desired/needed (Phase II). Read More

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[Psychological factors of sleep and daytime complaints during the COVID-19 Lockdown: the role of anxiety, well-being, autonomy, and coping].

E I Rasskazova

Zh Nevrol Psikhiatr Im S S Korsakova 2021 ;121(4. Vyp. 2):24-30

Lomonosov Moscow State University, Moscow, Russia.

Objective: To reveal psychological (anxiety, coping with pandemic stress, autonomy) and behavioral (compliance with recommendations, monitoring information) factors associated with complaints of sleep and daytime functioning disturbances during the lockdown period in the spring of 2020.

Material And Methods: Two hundred and three adults (106 men and 97 women), aged 18 to 59 years, participated in the study. Participants filled the questionnaires 1-2 weeks after the start of the lockdown and 3-4 weeks after the first measurement. Read More

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Discovery of Association Rules Patterns and Prevalence of Comorbidities in Adult Patients Hospitalized with Mental and Behavioral Disorders.

Healthcare (Basel) 2021 May 27;9(6). Epub 2021 May 27.

Department of Health Administration & Healthcare, Cheongju University, Cheongju 28503, Korea.

The objectives of this study were to identify the prevalence of comorbidities of mental and behavioral disorders and to identify the association rules related to comorbidities as a way to improve patient management efficiently. We extracted comorbidities of 20,690 patients (≥19 years old) whose principal diagnosis was a mental disorder from the Korean National Hospital Discharge In-depth Injury Survey (KNHDS) between 2006 and 2016. Association rules analysis between comorbid diseases using the Apriori algorithm was used. Read More

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A unifying translational framework to advance treatment research for comorbid PTSD and substance use disorders.

Neurosci Biobehav Rev 2021 May 29;127:779-794. Epub 2021 May 29.

Psychology Department, The City College of New York, New York, NY, United States.

We provide a unifying translational framework that can be used to synthesize extant lines of human laboratory research in four neurofunctional domains that underlie the co-occurrence of posttraumatic stress and substance use disorders (PTSD+SUD). We draw upon the Alcohol and Addiction Research Domain Criteria (AARDOC) to include executive functioning, negative emotionality, reward, and added social cognition from the National Institute of Mental Health (NIMH) Research Domain Criteria into our framework. We review research findings across each of the four domains, emphasizing human experimental studies in PTSD, SUD, and PTSD+SUD for each domain. Read More

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An Australian Cross-Sectional Survey of Parents' Experiences of Emergency Department Visits Among Children with Autism Spectrum Disorder.

J Autism Dev Disord 2021 Jun 1. Epub 2021 Jun 1.

Turner Institute for Brain and Mental Health and School of Psychological Sciences, Monash University, Level 5, 18 Innovation Walk, Melbourne, VIC, 3800, Australia.

Parents of children with ASD who had attended an Australian emergency department (ED; n = 421) completed a questionnaire relating to their experiences in the ED, including (1) child's reason for presentation and existing comorbidities, (2) quality of care during the visit (3) child's behaviour during visit, e.g. sensory responses to the ED environment, and disruptive behaviours. Read More

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