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Lyme Disease Training and Knowledge Translation Resources Available to Canadian Healthcare Professionals: A Gray Literature Review.

J Prim Care Community Health 2021 Jan-Dec;12:21501327211050744

Queen's University, Kingston, ON, Canada.

Introduction: Lyme Disease (LD) is the most common tick-borne disease in North America. With the number of cases increasing yearly, Canadian healthcare professionals (HCP) rely on up-to-date and evidence-informed guidelines, instruction, and resources to effectively prevent, diagnose, and treat Lyme disease (LD). This review is the first of its kind to examine gray literature and analyze the diversity of recommendations provided to Canadian HCP about the prevention, diagnosis, and treatment of Lyme disease. Read More

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October 2021

GreeningDB: A Database of Host-Pathogen Protein-Protein Interactions and Annotation Features of the Bacteria Causing Huanglongbing HLB Disease.

Int J Mol Sci 2021 Oct 8;22(19). Epub 2021 Oct 8.

Department of Plants, Soils and Climate, Utah State University, Logan, UT 84322, USA.

The genus comprises some of the most important and commonly cultivated fruit plants. Within the last decade, citrus greening disease (also known as huanglongbing or HLB) has emerged as the biggest threat for the citrus industry. This disease does not have a cure yet and, thus, many efforts have been made to find a solution to this devastating condition. Read More

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October 2021

LitCovid-AGAC: cellular and molecular level annotation data set based on COVID-19.

Genomics Inform 2021 Sep 30;19(3):e23. Epub 2021 Sep 30.

Hubei Key Lab of Agricultural Bioinformatics, College of Informatics, Huazhong Agricultural University, 430070 Wuhan, China.

Currently, coronavirus disease 2019 (COVID-19) literature has been increasing dramatically, and the increased text amount make it possible to perform large scale text mining and knowledge discovery. Therefore, curation of these texts becomes a crucial issue for Bio-medical Natural Language Processing (BioNLP) community, so as to retrieve the important information about the mechanism of COVID-19. PubAnnotation is an aligned annotation system which provides an efficient platform for biological curators to upload their annotations or merge other external annotations. Read More

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September 2021

A bibliometric analysis of international publications and citation trends of articles in mental health produced by Chinese institutions in mainland China (1990-2019).

Glob Ment Health (Camb) 2021 28;8:e37. Epub 2021 Sep 28.

Clinical Epidemiology and Biometric Unit, Foundation IRCCS, Policlinico San Matteo, Pavia, Italy.

Background: The recognition of the importance of mental health as a health-target to be pursued at a global level has received additional theoretical legitimacy through its inclusion in the United Nations (UN) 2030 Agenda for Sustainable development. The theoretical axiom - mental health as a development priority - is today expected to drive the focus of research efforts and orient the future policies and funds expenditures, at global and local level. According to these premises, it becomes central to track the international trajectories of mental health research and how the different countries are progressively defining their role in the global mental health effort. Read More

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September 2021

Natural products: Potential targets of TME related long non-coding RNAs in lung cancer.

Phytomedicine 2021 Sep 28;93:153782. Epub 2021 Sep 28.

West China School of Nursing / Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China; King Fahd Medical Research Center, King Abdulaziz University, P. O. Box 80216, Jeddah 21589, Saudi Arabia; Enzymoics, Novel Global Community Educational Foundation, Australia.

Background: Lung cancer is a significant health concern worldwide due to high mortality and morbidity, despite the advances in diagnosis, treatment, and management. Recent experimental evidence from different models suggested long non-coding RNAs (lncRNAs) as major modulators of cancer stem cells (CSCs) in the tumor microenvironment (TME) to support metastasis and drug resistance in lung cancer. Evidence-based studies demonstrated that natural products interfere with TME functions. Read More

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September 2021

The experiences of children and adolescents undergoing forced separation from their parents during migration: A systematic review.

Health Soc Care Community 2021 Oct 7. Epub 2021 Oct 7.

Department of Epidemiology and Preventative Medicine, Monash University, Melbourne, Victoria, Australia.

Globally, the migration of unaccompanied minors is increasing, however, the experiences of these children have not been examined. We systematically synthesised the existing qualitative literature to examine the experiences of children undergoing forced separation from their parents during migration. The review was structured based on the PRISMA statement. Read More

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October 2021

Appropriation of mHealth Interventions for Maternal Health Care in Sub-Saharan Africa: Hermeneutic Review.

JMIR Mhealth Uhealth 2021 Oct 6;9(10):e22653. Epub 2021 Oct 6.

Department of Information Systems, Faculty of Commerce, University of Cape Town, Cape Town, South Africa.

Background: Many maternal clients from poorly resourced communities die from preventable pregnancy-related complications. The situation is especially grave in sub-Saharan Africa. Mobile health (mHealth) interventions have the potential to improve maternal health outcomes. Read More

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October 2021

SicknessMiner: a deep-learning-driven text-mining tool to abridge disease-disease associations.

BMC Bioinformatics 2021 Oct 4;22(1):482. Epub 2021 Oct 4.

Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000-456, Coimbra, Portugal.

Background: Blood cancers (BCs) are responsible for over 720 K yearly deaths worldwide. Their prevalence and mortality-rate uphold the relevance of research related to BCs. Despite the availability of different resources establishing Disease-Disease Associations (DDAs), the knowledge is scattered and not accessible in a straightforward way to the scientific community. Read More

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October 2021

The role of social media for patients with temporomandibular disorders: A content analysis of Reddit.

J Oral Rehabil 2021 Sep 30. Epub 2021 Sep 30.

Tufts University School of Dental Medicine, Boston, Massachusetts, USA.

Background: Social media is frequently used to discuss health topics among users. Reddit is a popular social media platform particularly suit for discussion about chronic illness because of its anonymity that allow users to express uninhibited feelings. Temporomandibular disorders (TMD) represent a chronic painful disorder which has been rarely studied in terms of social media discussion. Read More

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September 2021

Scoping Review of Off-Label Topical Analgesia in Palliative, Hospice and Cancer Care: Towards Flexibility in Evidence-Based Medicine.

J Pain Res 2021 22;14:3003-3009. Epub 2021 Sep 22.

Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA.

Purpose: Scoping reviews address the nature of the literature per se rather than inferring evidence-based treatment guidelines. Scoping reviews of the published literature are intended to describe the aggregated nature of the evidence surrounding some agent or intervention, in contrast to systematic reviews that seek when possible to guide clinical practice. We conducted a scoping review to identify reports of potential clinical utility of off-label topical analgesics and adjuvants when FDA-approved treatments have proven inadequate. Read More

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September 2021

Decrease of Pneumococcal Community-Acquired Pneumonia Hospitalization and Associated Complications in Children after the Implementation of the 13-Valent Pneumococcal Conjugate Vaccine (PCV13) in Taiwan.

Vaccines (Basel) 2021 Sep 18;9(9). Epub 2021 Sep 18.

Department of Pharmacy, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.

The impact of the 13-valent pneumococcal conjugate vaccine (PCV13) on overall community-acquired pneumonia (CAP) and disease severity still needs thorough evaluation. In this study, we retrieve both pneumococcal CAP (P-CAP) and unspecific CAP (U-CAP) inpatient data from the Taiwan National Health Insurance Database (NHID) between 2005 and 2016. The interrupted time-series (ITS) analysis was performed to compare the incidence trend before and after the implementation of PCV13. Read More

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September 2021

Impact of COVID-19 on utilization of maternal, newborn and child health services in Nigeria: protocol for a country-level mixed-methods study.

F1000Res 2020;9:1106. Epub 2020 Sep 9.

Department of Obstetrics and Gynaecology, General Hospital, Takum, Taraaba, Nigeria.

Battling with COVID-19 and providing essential services along the continuum of care could be challenging. This study will evaluate the impact of COVID-19 on utilization of maternal, newborn and child health (MNCH) services in Nigeria and explore the barriers being experienced by women and their families in getting access to MNCH services, as well as other contextual factors that may have shaped the utilization of MNCH services during the COVID-19 pandemic. The study will adopt an observational mixed-methods study design involving 18 health care facilities delivering MNCH services in six selected states across six geopolitical zones of Nigeria. Read More

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September 2021

International Gynaecological Cancer Society (IGCS) 2020 Annual Global Meeting: Twitter activity analysis.

Int J Gynecol Cancer 2021 Sep 6. Epub 2021 Sep 6.

Newcastle University, Business School, Newcastle, UK.

Objectives: Twitter is the most frequently used social media platform by healthcare practitioners, at medical conferences. This study aimed to analyze Twitter conversations during the virtual International Gynecological Cancer Society 2020 conference to understand the interactions between Twitter users related to the conference.

Methods: Tweets using the hashtag '#IGCS2020' were searched using the Twitter Search Application Programming Interface (API) during the period 10-13 September 2020. Read More

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September 2021

Developed and validated food frequency questionnaires in Iran: A systematic literature review.

J Res Med Sci 2021 31;26:50. Epub 2021 Jul 31.

Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Background: Food frequency questionnaires (FFQs) are inexpensive, easy to administer, and practical tools for dietary assessment in epidemiological studies. Several studies have investigated the validity and reproducibility of FFQs for the Iranian population. This systematic review aimed to assess the developed and validated FFQs for use in the Iranian population and compare their features and the validation studies in this regard. Read More

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The indicators and methods used for measuring urban liveability: a scoping review.

Rev Environ Health 2021 Sep 18;36(3):397-441. Epub 2020 Dec 18.

Climate, Air Quality Research Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.

Objectives: Liveability is a multi-dimensional and hierarchical concept which consists of various criteria and sub-criteria and may be evaluated in different ways. The aim of this study was to systematically review indicators and methods used for the evaluation of urban liveability in literature.

Content: The five-stage methodological framework of Arksey and O'Malley was used to conduct this scoping review. Read More

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September 2021

A Policy-Driven Approach to Secure Extraction of COVID-19 Data From Research Papers.

Front Big Data 2021 12;4:701966. Epub 2021 Aug 12.

IS Department, University of Maryland Baltimore County, Baltimore, MD, United States.

The entire scientific and academic community has been mobilized to gain a better understanding of the COVID-19 disease and its impact on humanity. Most research related to COVID-19 needs to analyze large amounts of data in very little time. This urgency has made Big Data Analysis, and related questions around the privacy and security of the data, an extremely important part of research in the COVID-19 era. Read More

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Novel severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection: Microbiologic perspectives and anatomic considerations for sanctuary sites.

J Infect Public Health 2021 Sep 20;14(9):1237-1246. Epub 2021 Aug 20.

Discipline of Clinical Anatomy, School of Laboratory Medicine & Medical Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, 719 Umbilo Road, Durban, South Africa.

Introduction: A significant chunk of global life - the economy, sports, aviation, academic, and entertainment activities - has significantly been affected by the ravaging outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) with devastating consequences on morbidity and mortality in many countries of the world.

Methods: This review utilized search engines such as google scholar, PubMed, ResearchGate, and web of science to retrieve articles and information using keywords like "Coronavirus", "SARS-CoV-2", "COVID-19", "Origin of coronavirus and SARS-CoV-2", "microbiology of coronavirus", "microbiology of SARS-CoV-2", COVID-19", "Coronavirus reservoir sites", "Anatomic sanctuary sites and SARS-CoV-2", biological barriers and coronavirus", biological barrier and SARS-CoV-2".

Results: While this pandemic has caught the global scientific community at its lowest level of preparedness, it has inadvertently created a unified and wholesome approach towards developing potential vaccine (s) candidates by escalating clinical trial protocols in many countries of Europe, China and the United States. Read More

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September 2021

A systematic review and meta-analysis of the prevalence and predictors of anemia among children in Ethiopia.

Afr Health Sci 2020 Dec;20(4):2007-2021

Department of Nursing, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.

Background: Anemia is a wide-spread public health problem characterized by a decrease in hemoglobin concentration and/ or red blood cell volume below an established cut-off value. In developing countries including Ethiopia, about half of children are estimated to be anemic. Therefore, the purpose of this study was to determine the pooled prevalence of anemia and its predictor factors among children in Ethiopia. Read More

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December 2020

Contribution of faculties of pharmacy in Arab countries to pharmacy practice research: a bibliometric analysis (1990-2020).

Waleed M Sweileh

Int J Pharm Pract 2021 Aug 6. Epub 2021 Aug 6.

Department of Physiology, Pharmacology/Toxicology, Division of Biomedical Sciences, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.

Objective: To provide an overview of pharmacy practice research by faculties of pharmacy in the Arab region using a bibliometric methodology.

Method: Relevant articles were retrieved from SciVerse Scopus. The search strategy was developed to retrieve all articles published in pharmacy practice journals and those with specific keywords such as 'clinical pharmacy', 'community pharmacy', 'hospital pharmacy', 'pharmacy education' and 'pharmacy practice'. Read More

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Suitability of Google Trends™ for Digital Surveillance During Ongoing COVID-19 Epidemic: A Case Study from India.

Disaster Med Public Health Prep 2021 Aug 3:1-10. Epub 2021 Aug 3.

Department of Community and Family Medicine, All India Institute of Medical Sciences (AIIMS), Bhopal, Madhya Pradesh, India.

Objective: Digital surveillance has shown mixed results as a supplement to traditional surveillance. Google Trends™ (GT) (Google, Mountain View, CA, United States) has been used for digital surveillance of H1N1, Ebola and MERS. We used GT to correlate the information seeking on COVID-19 with number of tests and cases in India. Read More

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Prevalence of COVID-19 genomic variation in Africa: a living systematic review protocol.

JBI Evid Synth 2021 Aug 2. Epub 2021 Aug 2.

Department of Community Medicine, School of Medical Sciences, University of Cape Coast, Cape Coast, Ghana The Kintampo Health Research Centre: A JBI Centre of Excellence, Kintampo, Ghana Department of Epidemiology and Biostatistics, School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana Department of Medical Biochemistry, School of Medical Sciences, University of Cape Coast, Cape Coast, Ghana Division of Human Genetics, Department of Pathology, University of Cape Town, Cape Town, South Africa.

Objective: The objective of this living systematic review is to synthesize the available evidence on the prevalence of types of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomic variations in Africa.

Introduction: The burden of the coronavirus disease 2019 (COVID-19) pandemic on the health, well-being, and global economy (especially the fragile economies of African countries) is significant. Profiling the genomic and geographical variations of SARS-CoV-2, a causative agent of COVID-19, may be important for future decision-making, policy guidelines, and development of drugs and vaccines. Read More

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Assessing changes in stream macroinvertebrate communities across ecological gradients using morphological versus DNA metabarcoding approaches.

Sci Total Environ 2021 Nov 14;797:149030. Epub 2021 Jul 14.

CIBIO/InBio, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, Campus de Vairão, Vila do Conde, Portugal; CIBIO/InBio, Centro de Investigação em Biodiversidade e Recursos Genéticos, Instituto Superior de Agronomia, Universidade de Lisboa, Lisboa, Portugal.

Freshwater macroinvertebrates provide valuable indicators for biomonitoring ecosystem change in relation to natural and anthropogenic drivers. DNA metabarcoding is an efficient approach for estimating such indicators, but its results may differ from morphotaxonomic approaches traditionally used in biomonitoring. Here we test the hypothesis that despite differences in the number and identity of taxa recorded, both approaches may retrieve comparable patterns of community change, and detect similar ecological gradients influencing such changes. Read More

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November 2021

Ethical Problems and Moral Distress in Primary Care: A Scoping Review.

Int J Environ Res Public Health 2021 07 16;18(14). Epub 2021 Jul 16.

Center for Nursing Research and Innovation, Vita-Salute San Raffaele University, 20132 Milan, Italy.

Background: Since 1997, nursing ethics research has focused on solving ethical dilemmas, enhancing decision-making strategies, and introducing professional education. Few studies describe the triggers of ethical dilemmas among primary care nurses. The aim of this study was to explore the moral distress and ethical dilemmas among primary care nurses. Read More

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Bibliometric analysis of global scientific literature on effects of COVID-19 pandemic on mental health.

Asian J Psychiatr 2021 Sep 10;63:102753. Epub 2021 Jul 10.

Cognitive Psychology, Faculty of Arts- Menoufia University, Egypt. Electronic address:

The study provides a comprehensive analysis of trends of the global scientific research on the effects of the COVID-19 Pandemic on Mental health from the first published literature up to June 27, 2021. Relevant documents were searched using mesh terms based on the query of two searches, "COVID-19 & Mental Health" scenarios joined by the Boolean operator "AND" to retrieve relevant literature using the Web of Science (WOS) database. Bibliometric indicators were analyzed using HistCite, Bibliometrix, an R package, and VOSviewer. Read More

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September 2021

Medicinal Plants Used for the Treatment of Erectile Dysfunction in Ethiopia: A Systematic Review.

Biomed Res Int 2021 7;2021:6656406. Epub 2021 Jun 7.

Department of Pharmacology and Toxicology, School of Pharmacy, College of Health Sciences, Mekelle University, P.O. Box 1871, Mekelle, Ethiopia.

Background: Erectile dysfunction has remained as one of the major global health issues. Since the discovery of phosphodiesterase type 5 inhibitors, a significant portion of the patients has solved the issue of erectile dysfunction. However, the wide distribution of phosphodiesterase type 5 enzymes at various sites of the body led phosphodiesterase type 5 inhibitors to cause various unnecessary outcomes. Read More

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Nanomaterial Databases: Data Sources for Promoting Design and Risk Assessment of Nanomaterials.

Nanomaterials (Basel) 2021 Jun 18;11(6). Epub 2021 Jun 18.

National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.

Nanomaterials have drawn increasing attention due to their tunable and enhanced physicochemical and biological performance compared to their conventional bulk materials. Owing to the rapid expansion of the nano-industry, large amounts of data regarding the synthesis, physicochemical properties, and bioactivities of nanomaterials have been generated. These data are a great asset to the scientific community. Read More

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Long-term effectiveness of group-based diabetes self-management on glycosylated haemoglobin for people with type 2 diabetes in community: a protocol of systematic review and meta-analysis.

BMJ Open 2021 06 30;11(6):e046692. Epub 2021 Jun 30.

National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China

Introduction: The rapid rise in the prevalence of diabetes has a negative impact on patients' quality of life. Diabetes self-management group education is cost-effective and efficient for patients to control blood glucose. However, there are no consistent standards for self-management group education, and its long-term effects (≥12 months) are unclear. Read More

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National Methodological Guidelines to Conduct Budget Impact Analysis for Health Technology Assessment in India.

Appl Health Econ Health Policy 2021 Jun 29. Epub 2021 Jun 29.

Department of Humanities and Social Sciences, Centre for Technology and Policy (CTaP), Indian Institute of Technology, Madras, India.

Objective: Our paper aims to present Budget Impact Analysis (BIA) guidelines for health technology assessment (HTA) in India.

Methodology: A Systematic Literature Review (SLR) was conducted to retrieve information on existing BIA guidelines internationally. The initial set of principles for India were put together based on an interactive process between authors, taking into consideration the existing evidence on BIA and features of Indian healthcare system. Read More

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In-text citation's frequencies-based recommendations of relevant research papers.

PeerJ Comput Sci 2021 4;7:e524. Epub 2021 Jun 4.

Information Systems Department, College of Computer and Information Sciences, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.

From the past half of a century, identification of the relevant documents is deemed an active area of research due to the rapid increase of data on the web. The traditional models to retrieve relevant documents are based on bibliographic information such as Bibliographic coupling, Co-citations, and Direct citations. However, in the recent past, the scientific community has started to employ textual features to improve existing models' accuracy. Read More

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