Am J Dermatopathol 2021 May 11. Epub 2021 May 11.
Medical Student, College of Medicine, Texas A&M Health Science Center, Houston, TX; Resident Physician, Department of Pathology, Baylor Scott and White Medical Center, Temple, TX; Intern, Department of Internal Medicine, University of Texas Austin Dell Medical School, Austin, TX; Clinical Assistant Professor, Department of Dermatology, Baylor Scott and White Medical Center, Temple, TX; and Clinical Associate Professor, Department of Dermatology and Pathology, Baylor Scott and White Medical Center, Temple, TX.
Abstract: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy that frequently has cutaneous manifestations. The diagnosis can be a challenge because of its heterogenous clinical presentation, ranging from a brown or violaceous solitary nodule or patch to mixed, disseminated lesions. Furthermore, BPDCN tumor cells express immunohistochemical markers in common with acute myeloid leukemia, which can lead to misdiagnosis. Read More