J Eur Acad Dermatol Venereol 2021 Sep 22. Epub 2021 Sep 22.
Dermatology Department, Coimbra University Hospital Center, Coimbra, Portugal.
Cold urticaria (ColdU) is a common type of inducible urticaria, characterized by the appearance of wheals, angioedema or both upon cold exposure, either by direct contact or exposure to a cold ambient. Patients may have generalized cutaneous lesions and up to 30% may develop systemic symptoms, including dizziness, nausea, diarrhoea, abdominal pain, muscle weakness, respiratory distress or even anaphylaxis. ColdU can be familial or acquired, the latter being further classified into primary or secondary to an underlying cause, such as cryoglobulins, infections or drugs. Read More