55,220 results match your criteria common complication

Influenza-Associated Neurologic Complications in Hospitalized Children.

J Pediatr 2021 Jul 19. Epub 2021 Jul 19.

Divisions of Neurology, The Children's Hospital of Philadelphia; Departments of Neurology, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA. Electronic address:

Objectives: To define the incidence and characteristics of influenza-associated neurologic complications in a cohort of children hospitalized at a tertiary care pediatric hospital with laboratory-confirmed influenza, and to identify associated clinical, epidemiologic, and virologic factors.

Study Design: Historical cohort study of children 0.5-18. Read More

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ENDOCRINOLOGY IN THE TIME OF COVID-19 - 2021 updates: The Management of Diabetes insipidus and Hyponatraemia.

Eur J Endocrinol 2021 Jul 1. Epub 2021 Jul 1.

M Sherlock, Endocrinology, The Adelaide and Meath Hospital, Incorporating the National Children's Hospital, Tallaght, Dublin 24 , Dublin, Ireland.

COVID-19 has changed the nature of medical consultations, emphasizing virtual patient counseling, with relevance for patients with diabetes insipidus (DI) or hyponatremia. The main complication of desmopressin treatment in DI is dilutional hyponatraemia. Since plasma sodium monitoring is not always possible in times of COVID-19, we recommend to delay the desmopressin dose once a week until aquaresis occurs allowing excess retained water to be excreted. Read More

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Clinical and Radiological Outcomes in Reverse Total Shoulder Arthroplasty by Inclination Angle With a Modular Prosthesis.

Orthopedics 2021 Jul-Aug;44(4):e527-e533. Epub 2021 Jul 1.

The influence of the humeral inclination in reverse total shoulder arthroplasty (RTSA) is not well understood. The purpose of this study was to determine outcomes and complications after RTSA with an inclination of 135° or 155° in a modular prosthesis. American Shoulder and Elbow Surgeons (ASES), visual analog scale (VAS), Single Assessment Numeric Evaluation (SANE), and Simple Shoulder Test (SST) scores, as well as forward elevation (FE), abduction (ABD), and external rotation (ER), were assessed after a minimum 2-year follow-up. Read More

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Acute Common Peroneal Nerve Decompression After Total Knee Arthroplasty.

Orthopedics 2021 Jul-Aug;44(4):e556-e562. Epub 2021 Jul 1.

Common peroneal nerve palsy (CPNP) after total knee arthroplasty has a reported incidence of 0.3% to 4% and can lead to foot drop, equinovarus deformity, and marked disability if not resolved. Patients typically present in the early postoperative period with weakness or inability to dorsiflex the ankle and decreased sensation of the dorsum of the foot. Read More

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Mechanisms and management of drug-induced hyperkalemia in kidney transplant patients.

Rev Endocr Metab Disord 2021 Jul 22. Epub 2021 Jul 22.

Department of Medicine, Division of Nephrology, Hypertension and Kidney Transplantation, School of Medicine, University of California, CA, Irvine, Orange, USA.

Hyperkalemia is a common and potentially life-threatening complication following kidney transplantation that can be caused by a composite of factors such as medications, delayed graft function, and possibly potassium intake. Managing hyperkalemia after kidney transplantation is associated with increased morbidity and healthcare costs, and can be a cause of multiple hospital admissions and barriers to patient discharge. Medications used routinely after kidney transplantation are considered the most frequent culprit for post-transplant hyperkalemia in recipients with a well-functioning graft. Read More

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Same Day Surgical Intervention Dramatically Minimizes Complication Occurrence and Optimizes Perioperative Outcomes for Central Cord Syndrome.

Clin Spine Surg 2021 Jul 21. Epub 2021 Jul 21.

Department of Orthopaedics, NYU Langone Orthopedic Hospital, New York, NY Department of Pediatric Neurosurgery, UT Southwestern Medical Center, Dallas, TX Department of Neurologic Surgery, University of Michigan, Ann Arbor, MI Department of Orthopaedic Surgery, University of Calgary, Calgary, AB, Canada Department of Neurological Surgery Montefiore Medical Center/Albert Einstein College of Medicine Bronx, NY Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD Deparment of Orthopedic Surgery, SUNY Downstate, New York, NY.

Study Design: This was a retrospective cohort study.

Objective: The aim of this study was to investigate associations between time to surgical intervention and outcomes for central cord syndrome (CCS) patients.

Background: As surgery is increasingly recommended for patients with neurological deterioration CCS, it is important to investigate the relationship between time to surgery and outcomes. Read More

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Genetic variation of rs12918566 affects GRIN2A expression and is associated with spontaneous movement response during sevoflurane anesthesia induction.

Brain Behav 2021 Jul 21:e02165. Epub 2021 Jul 21.

Department of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, China.

N-methyl-D-aspartate (NMDA) receptors mediate excitatory neurotransmission in the nervous system and are preferentially inhibited by general anesthetics such as sevoflurane. Spontaneous movement is a common complication during sevoflurane anesthesia induction and seriously affects operations. In this study, we investigated the relationship between NMDA polymorphisms and spontaneous movement during sevoflurane induction. Read More

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Risk prediction score and appendicectomy in the elderly: A single centre 5-year retrospective cohort study.

ANZ J Surg 2021 Jul 21. Epub 2021 Jul 21.

General Surgery, Western Sussex Hospitals NHS Foundation Trust, Chicester, UK.

Background: Appendicitis is a common surgical emergency that can be a challenging entity to manage. In the elderly, it is associated with significant morbidity and mortality. Risk prediction is not routinely performed prior to surgery. Read More

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Sepsis-Associated Encephalopathy and Blood-Brain Barrier Dysfunction.

Inflammation 2021 Jul 21. Epub 2021 Jul 21.

Division of Cardiology, Department of Medicine, Emory University, 101 Woodruff Circle, WMB 308, Atlanta, GA, 30322, USA.

Sepsis is a life-threatening clinical condition caused by a dysregulated host response to infection. Sepsis-associated encephalopathy (SAE) is a common but poorly understood neurological complication of sepsis, which is associated with increased morbidity and mortality. SAE clinical presentation may range from mild confusion and delirium to severe cognitive impairment and deep coma. Read More

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Laser treatment of pilonidal disease: a systematic review.

Lasers Med Sci 2021 Jul 22. Epub 2021 Jul 22.

Department of Surgery, University Hospital Centre Zagreb, Kispaticeva 12, 10 000, Zagreb, Croatia.

Pilonidal disease (PD) is a common condition, and there is still an ongoing debate on ideal management that should be minimally invasive, safe, and efficient. The use of radially emitting laser in the treatment of chronic PD is a novel minimally invasive technique, and initial studies with a small number of patients showed promising results. This study aimed to assess the efficacy and safety of chronic PD treatment with a laser using a systematic review of the published literature. Read More

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Fulminant Infective Endocarditis Due to and Several Complications in a 6-Year-Old Girl: A Case Report.

Front Pediatr 2021 5;9:707760. Epub 2021 Jul 5.

Pediatric Cardiac Surgery Unit, Geneva University Hospitals, Geneva, Switzerland.

is a gram-negative coccobacillus belonging to the HACEK group ( species, , and species) and is a common oropharyngeal colonizer of healthy young children. Osteoarticular infection is the most commonly reported invasive infection in children, usually presenting a mild clinical picture. However, it can also cause severe invasive infections, especially infective endocarditis, with a high complication rate. Read More

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Surgical outcome of trans-sphenoidal approach to pituitary adenoma in adult patients: 10 years experience in northwest of Iran.

Med J Islam Repub Iran 2021 10;35:88. Epub 2021 Jul 10.

Department of Neurosurgery, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

Pituitary adenoma (PA) is a frequent intracranial lesion, that needs surgical evacuation. In this study, we evaluated the surgical outcome of PA treated via endoscopic and microscopic trans-sphenoidal approach. In this retrospective cross-sectional study, we evaluate ten years of PA surgery experience in the northwest of Iran. Read More

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Mechanical colon cleansing device in patients with chronic constipation: An experimental study.

Med J Islam Repub Iran 2021 30;35:84. Epub 2021 Jun 30.

Firoozgar Clinical Research and Development Center (FCRDC), Iran University of Medical Sciences, Tehran, Iran.

Constipation is one of the most common gastrointestinal discomforts that affects various age groups in humans. Different mechanical cleansing devices have been introduced yet. However, they are very expensive and not available in our country. Read More

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The Specific Connexin 43-Inhibiting Peptide Gap26 Improved Alveolar Development of Neonatal Rats With Hyperoxia Exposure.

Front Pharmacol 2021 5;12:587267. Epub 2021 Jul 5.

Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, China.

Bronchopulmonary dysplasia (BPD) is a common devastating pulmonary complication in preterm infants. Alveolar maldevelopment is the crucial pathological change of BPD highly associated with oxidative stress-mediated excessive apoptosis. Cellular injury can be propagated and amplified by gap junction (GJ)-mediated intercellular communication. Read More

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Immunotherapy-related gastritis: Two case reports and literature review.

Clin Med Insights Oncol 2021 9;15:11795549211028570. Epub 2021 Jul 9.

Coffs Harbour Health Campus, Coffs Harbour, Australia.

Immunotherapy is increasingly defining a role in a wide variety of tumours such that as use becomes more ubiquitous, so too will the complications. A relatively rare complication of immunotherapy use is immune-related gastritis. In this case series, we present two cases of immunotherapy-related gastritis from our institution and undertake a comprehensive review and analysis of the literature around this less common adverse event. Read More

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Diabetic Retinopathy in the Aging Population: A Perspective of Pathogenesis and Treatment.

Clin Interv Aging 2021 15;16:1367-1378. Epub 2021 Jul 15.

Department of Ophthalmology, Eugene and Marilyn Glick Eye Institute, Indiana University, Indianapolis, IN, USA.

The elderly population in the United States is projected to almost double by the year 2050. In addition, the numbers of diabetics are rising, along with its most common complication, diabetic retinopathy (DR). To effectively treat DR within the elderly population, it is essential first to consider the retinal changes that occur due to aging, such as decreased blood flow, retinal thinning, and microglial changes, and understand that these changes can render the retina more vulnerable to oxidative and ischemic damage. Read More

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Feasibility and diagnostic accuracy of Telephone Administration of an adapted wound heaLing QuestiONnaire for assessment for surgical site infection following abdominal surgery in low and middle-income countries (TALON): protocol for a study within a trial (SWAT).


Trials 2021 Jul 21;22(1):471. Epub 2021 Jul 21.

Background: Surgical site infection is the most common complication of abdominal surgery, with a global impact on patients and health systems. There are no tools to identify wound infection that are validated for use in the global setting. The overall aim of the study described in this protocol is to evaluate the feasibility and validity of a remote, digital pathway for wound assessment after hospital discharge for patients in low- and middle-income countries (LMICs). Read More

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Management of chronic knee pain caused by postsurgical or posttraumatic neuroma of the infrapatellar branch of the saphenous nerve.

J Orthop Surg Res 2021 Jul 21;16(1):464. Epub 2021 Jul 21.

The Peripheral Nerve Reconstruction Unit, Department of Neurosurgery and Orthopedic Surgery, Tel Aviv University, Tel Aviv, Israel.

Purpose: Injury to the infrapatellar branch of the saphenous nerve (IBSN) is a relatively common complication after knee surgery, which can interfere with patient satisfaction and functional outcome. In some cases, injury to the IBSN can lead to formation of a painful neuroma. The purpose of this study was to report the results of surgical treatment in a series of patients with IBSN painful neuroma. Read More

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High-frequency (10 kHz) spinal cord stimulation for the treatment of focal, chronic postsurgical neuropathic pain: results from a prospective study in Belgium.

Pain Manag 2021 Jul 22. Epub 2021 Jul 22.

Department of Clinical and Regulatory Affairs, Nevro Corp., Redwood City, CA 94065, USA.

Chronic postsurgical pain (CPSP) is a common complication of surgery. This study was conducted to evaluate the efficacy and safety of paresthesia-free, 10-kHz spinal cord stimulation (SCS) as a treatment for CPSP. Subjects in this prospective, single-arm study had an average pain intensity of ≥5 cm on a 10-cm visual analog scale. Read More

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Is It Possible to Save the Deep Brain Stimulation Hardware when Presenting with Wound Dehiscence or Hardware Infection?

Stereotact Funct Neurosurg 2021 Jul 21:1-10. Epub 2021 Jul 21.

Department of Neurosurgery, Rutgers-Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.

Introduction: Deep brain stimulation (DBS) hardware complications have been traditionally managed by removal of the entire system. Explantation of the system results in prolonged interruption to the patient's care and potential challenges when considering reimplantation of the cranial leads. The purpose of this study was to understand whether complete explantation can be avoided for patients initially presenting with wound dehiscence and/or infection of hardware. Read More

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Is Mucormycosis an inevitable complication of Covid-19 in India?

Braz J Infect Dis 2021 Jul 5:101597. Epub 2021 Jul 5.

Junior Research Fellow, Central Council for Research in Siddha (Ministry of AYUSH), Siddha Central Research Institute, Department of Pharmacology, Arumbakkam, Chennai, amilnadu, India.

Mucormycosis or black fungus infection is a less common disease but highly fatal infection, infecting the immunocompromised individuals. The site of predilection of the fungus is found to be lungs and brain in addition to its sequestration in sinusoidal spaces. Presently with the ongoing COVID 19 pandemic, the prevalence of this infection is found to be high in the Indian population. Read More

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NR4A1 modulates inflammation-associated intestinal fibrosis and dampens fibrogenic signaling in myofibroblasts.

Am J Physiol Gastrointest Liver Physiol 2021 07 21. Epub 2021 Jul 21.

Department of Physiology and Pharmacology, University of Calgary, Calgary, AB, Canada.

Background: Intestinal fibrosis is a common complication of the inflammatory bowel diseases(IBD), contributing to tissue stiffening and luminal narrowing. NR4A1 was previously reported to regulate mesenchymal cell function and dampen fibrogenic signaling. NR4A1 gene variants are associated with IBD risk, and it has been shown to regulate intestinal inflammation. Read More

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Emerging Concepts in the Surgical Management of Peri-Acetabular Metastatic Bone Disease.

Curr Oncol 2021 Jul 17;28(4):2731-2740. Epub 2021 Jul 17.

Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON L8V 1C3, Canada.

The pelvis is a common site of metastatic bone disease. Peri-acetabular lesions are particularly challenging and can cause severe pain, disability and pathologic fractures. Surgical management of these lesions has historically consisted of cementoplasty for contained lesions and Harrington reconstructions for larger, more destructive lesions. Read More

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Appetite Stimulants for Treatment of Protein Energy Wasting of Chronic Kidney Disease.

Nephrol Nurs J 2021 May-Jun;48(3):267-273

Clinical Associate Professor, University of Mississippi School of Pharmacy, Department of Pharmacy Practice, Jackson, MS.

Nutritional and metabolic abnormalities, or protein energy wasting, is a common complication of chronic kidney disease, leading to significant morbidity and mortality. The cause of these abnormalities is multifactorial, and therefore, difficult to treat. The International Society of Renal Nutrition and Metabolism suggests appetite stimulants, including megestrol, dronabinol, mirtazapine, and cyproheptadine, as adjunctive treatment options in addition to parenteral or oral nutritional supplementation. Read More

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Exchange transfusion for neonatal hyperbilirubinemia: A multicenter, prospective study of Turkish Neonatal Society.

Turk Arch Pediatr 2021 Mar 6;56(2):121-126. Epub 2021 Jan 6.

Department of Pediatrics, Division of Neonatology, Ankara University Faculty of Medicine, Ankara, Turkey.

Objective: The frequency of neonatal exchange transfusion has declined in recent years, but is still performed in many countries. The procedure is associated with complications. The aim of the study was to determine the clinical features and etiologies of infants with hyperbilirubinemia who underwent exchange transfusion and evaluate the adverse events and clinical outcomes. Read More

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Erectile dysfunction among testicular cancer survivors: A systematic review and meta-analysis.

Heliyon 2021 Jul 3;7(7):e07479. Epub 2021 Jul 3.

Department of Psychiatry, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.

Background: Erectile dysfunction is one of the common complications of testicular cancer with a prevalence of 11.3%-84%. It has devastating effects on men and their partner's quality of life, sexual satisfaction, and sexual experience. Read More

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Passively Scattered Proton Therapy for Nonmelanoma Skin Cancer with Clinical Perineural Invasion.

Int J Part Ther 2021 25;8(1):285-293. Epub 2021 Jun 25.

Department of Radiation Oncology, University of Florida College of Medicine, Jacksonville, FL, USA.

Purpose: To report our experience with the delivery of passively scattered proton therapy in the management of nonmelanoma skin cancers with clinical perineural invasion.

Materials And Methods: We reviewed the medical records of patients who received definitive or postoperative proton therapy for nonmelanoma skin cancer with clinical perineural invasion at our institution and updated patient follow-up when possible. All patients were treated with curative intent with or without the delivery of concurrent systemic therapy. Read More

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Clinical Outcomes Following Dose-Escalated Proton Therapy for Skull-Base Chordoma.

Int J Part Ther 2021 25;8(1):179-188. Epub 2021 Jun 25.

Department of Radiation Oncology University of Florida College of Medicine, Jacksonville, FL, USA.

Purpose: To evaluate the effectiveness of external-beam proton therapy (PT) on local control and survival in patients with skull-base chordoma.

Materials And Methods: We reviewed the medical records of patients with skull-base chordoma treated with definitive or adjuvant high-dose PT and updated their follow-up when feasible. We assessed overall survival, disease-specific survival, local control, and freedom from distant metastasis. Read More

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Electroencephalography Patterns of Subacute Sclerosing Panencephalitis.

Cureus 2021 Jun 17;13(6):e15728. Epub 2021 Jun 17.

Internal Medicine, Khyber Teaching Hospital, Peshawar, PAK.

Introduction And Background: This article explores the electroencephalography (EEG) pattern in patients of suspected subacute sclerosing panencephalitis (SSPE) visiting Lady Reading Hospital, Peshawar. Pakistan has a huge deficit of research culture, and limited studies are done on this topic. This study concluded that a typical pattern is the most common EEG pattern, although atypical and normal EEG patterns were also observed. Read More

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Hospital-Acquired Blood Stream Infection in an Adult Intensive Care Unit.

Crit Care Res Pract 2021 3;2021:3652130. Epub 2021 Jul 3.

Department of Critical Care Medicine, St Bartholomew's Hospital, Barts NHS Trust, London, UK.

Background: Hospital-acquired blood stream infections are a common and serious complication in critically ill patients.

Methods: A retrospective case series was undertaken investigating the incidence and causes of bacteraemia in an adult intensive care unit with a high proportion of postoperative cardiothoracic surgical and oncology patients.

Results: 405 eligible patients were admitted to the intensive care unit over the course of nine months. Read More

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