20,249 results match your criteria combined amount

The exploratory value of cross-sectional partial correlation networks: Predicting relationships between change trajectories in borderline personality disorder.

PLoS One 2021 30;16(7):e0254496. Epub 2021 Jul 30.

Department of Clinical Psychology, University of Amsterdam, Amsterdam, The Netherlands.

Objective: Within the network approach to psychopathology, cross-sectional partial correlation networks have frequently been used to estimate relationships between symptoms. The resulting relationships have been used to generate hypotheses about causal links between symptoms. In order to justify such exploratory use of partial correlation networks, one needs to assume that the between-subjects relationships in the network approximate systematic within-subjects relationships, which are in turn the results of some within-subjects causal mechanism. Read More

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Optical random speckle encoding based on hybrid wavelength and phase modulation.

Opt Lett 2021 Aug;46(15):3745-3748

Optical random speckle encoding suffers from a contradiction between the generation speed and pattern amount. Spatial light modulators are commonly used for random speckle generation at relatively low speeds. Wavelength scanning combined with a scattering medium has a fast speed, while the pattern amount is limited by the optical bandwidth. Read More

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Getting a better overview of a highly PAH contaminated soil: A non-targeted approach assessing the real environmental contamination.

J Hazard Mater 2021 Jun 8;418:126352. Epub 2021 Jun 8.

Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, D-45470 Mülheim/Ruhr, Germany. Electronic address:

Over the last 40 years, soils contaminated with polycyclic aromatic hydrocarbons (PAH) were monitored according to a list of 16 PAH, established by the U.S. Environmental Protection Agency (EPA). Read More

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Phytoplankton dynamics and renewable energy potential induced by the environmental conditions of Lake Burullus, Egypt.

Environ Sci Pollut Res Int 2021 Jul 29. Epub 2021 Jul 29.

Botany and Microbiology Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt.

The research evaluates the spatio-temporal phytoplankton community structure and abundance along with the pollution sources and the lake bioenergy potential, primarily in order to better understand the interplay of the environmental factors affecting them in inland coastal waters. Burullus Lake, located in the north of the Nile Delta of Egypt, is selected as a case study area. Field investigations along with sampling of lake water from 55 sites in the period 20-25 September 2020 are performed. Read More

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Targeted Glucose or Glutamine Metabolic Therapy Combined With PD-1/PD-L1 Checkpoint Blockade Immunotherapy for the Treatment of Tumors - Mechanisms and Strategies.

Front Oncol 2021 13;11:697894. Epub 2021 Jul 13.

Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao, China.

Immunotherapy, especially PD-1/PD-L1 checkpoint blockade immunotherapy, has led tumor therapy into a new era. However, the vast majority of patients do not benefit from immunotherapy. One possible reason for this lack of response is that the association between tumors, immune cells and metabolic reprogramming in the tumor microenvironment affect tumor immune escape. Read More

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Comparative anatomy of the middle ear in some lizard species with comments on the evolutionary changes within Squamata.

PeerJ 2021 22;9:e11722. Epub 2021 Jul 22.

Laboratorio de Sistemática Morfológica y Biogeografía de Vertebrados, Departamento de Biología Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, Cundinamarca, Colombia.

The skeleton of the middle ear of lizards is composed of three anatomical elements: columella, extracolumella, and tympanic membrane, with some exceptions that show modifications of this anatomy. The main function of the middle ear is transforming sound waves into vibrations and transmitting these to the inner ear. Most middle ear studies mainly focus on its functional aspects, while few describe the anatomy in detail. Read More

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Role of low-energy electrons in the solubility switch of Zn-based oxocluster photoresist for extreme ultraviolet lithography.

Phys Chem Chem Phys 2021 Jul 29. Epub 2021 Jul 29.

Institute for Applied and Physical Chemistry (IAPC), Fachbereich 2 (Chemie/Biologie), University of Bremen, Leobener Str. 5 (NW2), 28359 Bremen, Germany.

The electron-induced chemistry of a resist material for extreme ultraviolet lithography (EUVL) consisting of Zn oxoclusters with methacrylate (MA) and trifluoroacetate (TFA) ligands (Zn(MA)(TFA)) has been studied. Electron energies of 80 eV and 20 eV mimic the effect of photoelectrons released by the absorption of EUV photons and low-energy secondary electrons (LESEs) produced by those photoelectrons. The chemical conversion of the resist is studied by mass spectrometry to monitor the volatile species that desorb during electron irradiation, combined with reflection absorption infrared spectra (RAIRS) measured before and after irradiation. Read More

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Nitrogen removal performance of sulfur autotrophic denitrification under different SO additions using isotopic fractionation of nitrogen and oxygen.

Sci Total Environ 2021 Jul 1;794:148794. Epub 2021 Jul 1.

National Engineering Laboratory for Advanced Municipal Wastewater Treatment and Reuse Technology, Department of Environmental Engineering, Beijing University of Technology, Beijing 100124, China.

The dual isotope fractionation of nitrogen (N) and oxygen (O) is an effective way to track the transformation of NO-N in biological denitrification process. The Sulfur autotrophic denitrification combined with the different concentrations of SO was investigated using the dual isotope fractionation of nitrogen (N) and oxygen (O) to reveal the nitrogen removal mechanism of the activated sludge. Based on successful autotrophic denitrification incubation, the modified Logistic model responded to the short-term effects of SO addition on NO-N removal and SO generation. Read More

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Salinity influences on the response of Mytilus galloprovincialis to the rare-earth element lanthanum.

Sci Total Environ 2021 Jun 17;794:148512. Epub 2021 Jun 17.

Departamento de Biologia & CESAM, Universidade de Aveiro, 3810-193 Aveiro, Portugal. Electronic address:

The multiplicity and wide variety of applications of electrical and electronic equipment has largely increased with the technological and economic progress and, in consequence, the amount of generated waste of electrical and electronic equipment (WEEE). Due to inappropriate processing and disposal of WEEE, different chemical elements and compounds, including rare-earth elements such as Lanthanum (La) have been released in the environment. Nevertheless, the environmental risks resulting from La presence are almost unknown, especially in marine systems, which may be challenged by foreseen climate changes such as water salinity shifts. Read More

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Combination of wet fixation and drying treatments to improve dye fixation onto spray-dyed cotton fabric.

Sci Rep 2021 Jul 28;11(1):15403. Epub 2021 Jul 28.

Sanitary Environmental Engineering Division (SEED), Department of Civil Engineering, University of Salerno, via Giovanni Paolo II 132, 84084, Fisciano, SA, Italy.

The conventional dyeing process requires a substantial amount of auxiliaries and water, which leaches hazardous colored effluents to the environment. Herein, a newly developed sustainable spray dyeing system has been proposed for cotton fabric in the presence of reactive dyes, which has the potential to minimize the textile dyeing industries environmental impact in terms of water consumption and save significant energy. The results suggest that fresh dye solution can be mixed with an alkali solution before spray dyeing to avoid the reactive dye hydrolysis phenomenon. Read More

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The role of diffuse correlation spectroscopy and frequency-domain near-infrared spectroscopy in monitoring cerebral hemodynamics during hypothermic circulatory arrests.

JTCVS Tech 2021 Jun 29;7:161-177. Epub 2021 Jan 29.

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Mass.

Objectives: Real-time noninvasive monitoring of cerebral blood flow (CBF) during surgery is key to reducing mortality rates associated with adult cardiac surgeries requiring hypothermic circulatory arrest (HCA). We explored a method to monitor cerebral blood flow during different brain protection techniques using diffuse correlation spectroscopy (DCS), a noninvasive optical technique which, combined with frequency-domain near-infrared spectroscopy (FDNIRS), also provides a measure of oxygen metabolism.

Methods: We used DCS in combination with FDNIRS to simultaneously measure hemoglobin oxygen saturation (SO), an index of cerebral blood flow (CBF), and an index of cerebral metabolic rate of oxygen (CMRO) in 12 patients undergoing cardiac surgery with HCA. Read More

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Reboot: a straightforward approach to identify genes and splicing isoforms associated with cancer patient prognosis.

NAR Cancer 2021 Jun 15;3(2):zcab024. Epub 2021 Jun 15.

Centro de Oncologia Molecular, Hospital Sirio-Libanes, Sao Paulo, SP 01308-060, Brazil.

Nowadays, the massive amount of data generated by modern sequencing technologies provides an unprecedented opportunity to find genes associated with cancer patient prognosis, connecting basic and translational research. However, treating high dimensionality of gene expression data and integrating it with clinical variables are major challenges to perform these analyses. Here, we present Reboot, an integrative approach to find and validate genes and transcripts (splicing isoforms) associated with cancer patient prognosis from high dimensional expression datasets. Read More

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Quantifying Vocal Repertoire Tessituras Through Real-Time Measures.

J Voice 2021 Jul 25. Epub 2021 Jul 25.

Utah Center for Vocology, University of Utah, 240 S. 1500 E., Room 206, Salt Lake City, UT 84112.

Introduction: Voice teachers use anecdotal evidence and experience in determining the appropriateness of repertoire for each student's development. Tessitura is important in that determination, but until recently a straightforward, repeatable, and quantifiable method for determining tessitura has not existed. However, technology exists to provide the means to estimate the tessituras of standard vocal repertoire by measuring sung pitch (fundamental frequency) and vocal dose (amount of phonation) in real-time performance. Read More

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Magma Ocean Evolution of the TRAPPIST-1 Planets.

Astrobiology 2021 Jul 26. Epub 2021 Jul 26.

Max Planck Institute for Astronomy, Heidelberg, Germany.

Recent observations of the potentially habitable planets TRAPPIST-1 e, f, and g suggest that they possess large water mass fractions of possibly several tens of weight percent of water, even though the host star's activity should drive rapid atmospheric escape. These processes can photolyze water, generating free oxygen and possibly desiccating the planet. After the planets formed, their mantles were likely completely molten with volatiles dissolving and exsolving from the melt. Read More

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Effect of assay choice, viral concentration and operator interpretation on infectious bronchitis virus detection and characterization.

Avian Pathol 2021 Jul 27:1-16. Epub 2021 Jul 27.

Department of Animal Medicine, Production and Health (MAPS), Università degli Studi di Padova, Viale dell'Università, 16, 35020 Legnaro PD, Italy.

Despite the efforts to achieve a consistent classification scheme based on the complete S1 gene, the genetic characterization of infectious bronchitis virus (IBV) is often performed on partial S1 regions due to economic and time constraints in diagnostic routine. Sanger sequencing remains the most common and cost-effective option even if the analysis of samples where multiple field and vaccine strain populations coexist can lead to partial or misleading results.The present study aimed to evaluate the different diagnostic outcomes of three commonly used RT-PCR methods targeting two regions of the S1 gene. Read More

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Primary cardiac B cell lymphoma in an immunocompetent patient.

BMJ Case Rep 2021 Jul 26;14(7). Epub 2021 Jul 26.

Cardiology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Itabashi-ku, Tokyo, Japan.

Primary cardiac lymphoma is a rare entity of extranodal lymphoma and is observed with increasing frequency in immunocompromised hosts. However, a considerable proportion of cardiac lymphomas still occur in immunocompetent patients. We report the case of a 55-year-old immunocompetent Japanese man with a large amount of pericardial fluid and the presentation of heart failure secondary to primary cardiac B cell lymphoma, which was diagnosed by cytological examination of pericardial fluid and imaging. Read More

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How to optimize provincial PM reduction targets and paths for emerging industrialized countries? Fresh evidence from China.

Environ Sci Pollut Res Int 2021 Jul 22. Epub 2021 Jul 22.

School of Economics and Management, China University of Mining and Technology, Xuzhou, 221116, People's Republic of China.

Taking China as an example, this paper aims to design a path to reduce haze pollution in newly industrialized countries. Combined the principles of efficiency and equity, this study develops a Game Cross Equity Fixed Cost Allocation Model (Game-EFCAM) to optimize provincial PM reduction targets and put forward haze reduction paths. The main results are as follows: (1) Among the three egalitarian principles, pay-ability egalitarianism is the fairest, which serves as the convergence principle of Game-EFCAM. Read More

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Sediment quality assessment combining chemical and biological (non)target analysis.

Aquat Toxicol 2021 Jun 8;238:105883. Epub 2021 Jun 8.

Risk Assessment Research Center, Korea Institute of Ocean Science and Technology, Geoje 53201, Republic of Korea; Department of Ocean Science, Korea University of Science and Technology, Daejeon 34113, Republic of Korea. Electronic address:

Aquatic sediments act as a storage for diverse mixtures of organic and inorganic contaminants. Nevertheless, most evaluations of contaminated sediments have been limited to the assessment of concentrations of target compounds and lethal effects on some test species. To identify the organic contaminants causing sub-lethal effects of contaminated sediment, this study combined chemical and biological (non)target analysis involving comprehensive two-dimensional gas chromatography coupled with a time-of-flight Mass Spectrometer (GCxGC/ToF-MS) analysis, embryonic malformation and high-throughput sequencing (RNA-seq) analysis on developing flounder. Read More

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The effect of simulation-based education before a cadaver dissection course.

Anat Sci Educ 2021 Jul 26. Epub 2021 Jul 26.

Department of Anatomy, Aichi Medical University School of Medicine, Aichi, Japan.

Although the methods for medical education continue to evolve due to the development of medicines, the cadaver dissection course still plays a fundamental role. The cadaver dissection course allows students to learn to handle instruments correctly while actively exploring three-dimensional anatomy. However, dissection comes with the risk of accidental injury. Read More

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Quercetin and Luteolin Improve the Anticancer Effects of 5-Fluorouracil in Human Colorectal Adenocarcinoma Model: A Mechanistic Insight.

Nutr Cancer 2021 Jul 26:1-17. Epub 2021 Jul 26.

Department of Molecular Biology and Genetics, Faculty of Sciences, Ataturk University, Erzurum, Turkey.

The aim of this study was to investigate the antitumor effects of quercetin and luteolin combined with 5-Fluorouracil (5-FU) in HT-29 human colorectal cancer cells. Cell viability induced by quercetin, luteolin and combination of these compounds with 5-FU were determined by MTT assay, also Cell death detection Elisa assay and fluorescence microscopy were performed to investigate apoptotic effects. Hu-VEGF Elisa assay was employed to determine the effects of treatments on angiogenesis. Read More

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[Effects of Coconut Chaff Biochar Amendment on Methane and Nitrous Oxide Emissions from Paddy Fields in Hot Areas].

Huan Jing Ke Xue 2021 Aug;42(8):3931-3942

College of Tropical Crops, Hainan University, Haikou 570228, China.

Based on the rice-vegetable crop rotation model, in-situ measurements of nitrous oxide (NO) and methane (CH) emissions were conducted in double-cropping rice fields in Hainan to determine the impact of coconut chaff biochar on greenhouse gas emissions. The experiment involved four treatments:conventional farming fertilization (CON), nitrogen fertilizer combined with 20 t ·hm biochar (B1), nitrogen fertilizer combined with 40 t ·hm biochar (B2), and no nitrogen fertilizer, as the control (CK). The NO and CH emissions were measured using static chamber-gas chromatography during the two paddy seasons, and the global warming potential (GWP) and greenhouse gas intensity (GHGI) were also estimated. Read More

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Comparison of the effects of conventional physiotherapy and proprioception exercises on pain and ankle proprioception in patients with lumbar radiculopathy.

J Back Musculoskelet Rehabil 2021 Jul 13. Epub 2021 Jul 13.

Department of Occupational Therapy, Faculty of Health Sciences, Hacettepe University, Ankara, Turkey.

Background: Lumbar radiculopathy is characterized by a significant amount of backache causing loss of workforce and is a significant health problem frequently seen in the general population.

Objective: The purpose of this study was to compare the effects of conventional physiotherapy (CT) and proprioception exercises (PE) on ankle proprioception and lumbar pain between patients with lumbar radiculopathy and a healthy control group.

Methods: In this randomized clinical trial, 89 patients referred to the Physical Medicine and Rehabilitation outpatient clinic were selected through convenience sampling. Read More

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Clinical experience and cost evaluation of magnetic resonance imaging -only workflow in radiation therapy planning of prostate cancer.

Phys Imaging Radiat Oncol 2021 Jul 17;19:66-71. Epub 2021 Jul 17.

Department of Oncology and Radiotherapy, Turku University Hospital, Hämeentie 11, FI-20521 Turku, Finland.

Background And Purpose: In radiation therapy (RT), significant improvements have been made recently particularly in the practices of planning imaging. This study aimed to conduct a cost evaluation between magnetic resonance imaging (MRI) -only and combined computed tomography (CT) and MRI workflows.

Materials And Methods: The time-driven activity-based costing (TDABC) model was used to conduct a cost evaluation between the two workflows in those steps, where cost differences were expected. Read More

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Individual Subject Approaches to Mapping Sensory-Biased and Multiple-Demand Regions in Human Frontal Cortex.

Curr Opin Behav Sci 2021 Aug 11;40:169-177. Epub 2021 Jun 11.

Department of Psychological & Brain Sciences, Boston University, Boston, MA, USA.

Sensory modality, widely accepted as a key factor in the functional organization of posterior cortical areas, also shapes the organization of human frontal lobes. 'Deep imaging,' or the practice of collecting a sizable amount of data on individual subjects, offers significant advantages in revealing fine-scale aspects of functional organization of the human brain. Here, we review deep imaging approaches to mapping multiple sensory-biased and multiple-demand regions within human lateral frontal cortex. Read More

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Bone-Conduction Sensor Assisted Noise Estimation for Improved Speech Enhancement.

Interspeech 2018 Sep;2018:1180-1184

Department of Electrical and Computer Engineering University of California, San Diego.

State-of-the-art noise power spectral density (PSD) estimation techniques for speech enhancement utilize the so-called speech presence probability (SPP). However, in highly non-stationary environments, SPP-based techniques could still suffer from inaccurate estimation, leading to significant amount of residual noise or speech distortion. In this paper, we propose to improve speech enhancement by deploying the bone-conduction (BC) sensor, which is known to be relatively insensitive to the environmental noise compared to the regular air-conduction (AC) microphone. Read More

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September 2018

Rare isolated extra-hepatic bile duct injury: A case report.

World J Clin Cases 2021 Jul;9(20):5661-5667

Department of Hepatobiliary Surgery, The Affiliated Hospital of Yunnan University (The Second People's Hospital of Yunnan Province), Kunming 650000, Yunnan Province, China.

Background: Extra-hepatic bile duct injury (EHBDI) is very rare among all blunt abdominal injuries. According to literature statistics, it only accounts for 3%-5% of abdominal injuries, most of which are combined injuries. Isolated EHBDI is more rare, with a special injury mechanism, clinical presentation and treatment strategy, so missed diagnosis easily occurs. Read More

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Controversies' clarification regarding ribavirin efficacy in measles and coronaviruses: Comprehensive therapeutic approach strictly tailored to COVID-19 disease stages.

George D Liatsos

World J Clin Cases 2021 Jul;9(19):5135-5178

Department of Internal Medicine, "Hippokration" General Hospital, Athens 11527, Attiki, Greece.

Background: Ribavirin is a broad-spectrum nucleoside antiviral drug with multimodal mechanisms of action, which supports its longevity and quality as a clinical resource. It has been widely administered for measles and coronavirus infections. Despite the large amount of data concerning the use of ribavirin alone or in combination for measles, severe acute respiratory syndrome, Middle East respiratory syndrome, and coronavirus disease 2019 (COVID-19) outbreaks, the conclusions of these studies have been contradictory. Read More

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Evaluation of Acellular Dermal Matrix (ADM) as a Scaffold for Adipose-Derived Stem Cell Transfer in the Rat Model.

World J Plast Surg 2021 May;10(2):67-75

Department of Plastic & Reconstructive Surgery, Burn Research Center, Hazrat Fatima Hospital Iran University of Medical Sciences, Tehran, Iran.

Background: This study was designed for the evaluation of Acellular Dermal Matrix (ADM) as a scaffold for adipose-derived stem cell transferring in the rat model.

Methods: This experimental study was done in the Burn Research Center of Iran University of Medical Sciences and Bonyakhteh Research Center, Tehran, Iran according to the standards of laboratory animals. Overall, 26 healthy Sprague-Dawley rats were used. Read More

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Performance of Danaini larvae is affected by both exotic host plants and abiotic conditions.

Ecol Evol 2021 Jul 23;11(14):9876-9886. Epub 2021 Jun 23.

Programa de Pós-Graduação em Ecologia Instituto de Biologia Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil.

The consequences of the introduction of invasive plants for the diet of herbivorous insects have been little explored in nature where, potentially, abiotic and biotic factors operate. In this study, we examined the larval performance of two Neotropical Danaini butterflies when using either a native or an exotic Apocynaceae species as host plant in both field and laboratory experiments. Hosts greatly differ in their amount of latex exudation and other physicochemical traits, as well as in the amount of evolutionary time they have interacted with herbivores. Read More

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Pharmacokinetics and Tissue Distribution of Combined Triptolide and Paeoniflorin Regimen for Percutaneous Administration in Rats Assessed by Liquid Chromatography-Tandem Mass Spectrometry.

Evid Based Complement Alternat Med 2021 8;2021:8864273. Epub 2021 Jul 8.

Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.

Triptolide (TP) has shown potential in rheumatoid arthritis (RA) treatment, but the narrow therapeutic window limits its clinical application. In clinical practice, the compatibility of and is often used to attenuate the toxicity of TP, but its compatibility mechanism has not been fully elucidated. The aim of this study was to investigate the pharmacokinetics and tissue distribution of a combined regimen of TP and paeoniflorin (PF) after transdermal administration in male and female Sprague Dawley (SD) rats via a rapid and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method. Read More

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