12,934 results match your criteria columnar

Electric-Field-Induced Chirality in Columnar Liquid Crystals.

J Am Chem Soc 2021 Jun 11. Epub 2021 Jun 11.

Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.

We describe a novel class of tetraphenylbenzene-based discotic molecules with exceptional self-assembling properties. Absorption and fluorescence studies confirmed the formation of -type aggregates in solution. The discotic mesogens also show an enhancement of the emission upon aggregation. Read More

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GATA4 controls epithelial morphogenesis in the developing stomach to promote establishment of glandular columnar epithelium.

Cell Mol Gastroenterol Hepatol 2021 Jun 7. Epub 2021 Jun 7.

Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI, 53226 USA. Electronic address:

Background & Aims: The transcription factor GATA4 is broadly expressed in nascent foregut endoderm. As development progresses, GATA4 is lost in the domain giving rise to the stratified squamous epithelium of the esophagus and forestomach (FS), while it is maintained in the domain giving rise to the simple columnar epithelium of the hindstomach (HS). Differential GATA4 expression within these domains coincides with the onset of distinct tissue morphogenetic events, suggesting a role for GATA4 in diversifying foregut endoderm into discrete esophageal/FS and HS epithelial tissues. Read More

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Boron-Doped Polycyclic π-Electron Systems with an Antiaromatic Borole Substructure That Forms Photoresponsive B-P Lewis Adducts.

J Am Chem Soc 2021 Jun 10. Epub 2021 Jun 10.

Department of Chemistry, Graduate School of Science, and Integrated Research Consortium on Chemical Sciences (IRCCS), Nagoya University, Furo, Chikusa, Nagoya 464-8602, Japan.

Heteroatom doping is a powerful strategy to alter the electronic structure of polycyclic aromatic hydrocarbons (PAHs). Especially boron doping endows PAH scaffolds with electron-accepting character and Lewis acidic centers. Herein, we report that embedding a five-membered borole ring into a polycyclic skeleton imparts the π-system with antiaromatic character and thereby induces unique properties and behavior. Read More

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Asymmetric distribution of dynamin-2 and β-catenin relative to tight junction spikes in alveolar epithelial cells.

Tissue Barriers 2021 Jun 10:1929786. Epub 2021 Jun 10.

Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, USA.

Tight junctions between lung alveolar epithelial cells maintain an air-liquid barrier necessary for healthy lung function. Previously, we found that rearrangement of tight junctions from a linear, cortical orientation into perpendicular protrusions (tight junction spikes) is associated with a decrease in alveolar barrier function, especially in alcoholic lung syndrome. Using quantitative super-resolution microscopy, we found that spikes in control cells were enriched for claudin-18 as compared with alcohol-exposed cells. Read More

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Clinicopathological Characteristics and Recurrence-Free Survival of Rare Variants of Papillary Thyroid Carcinomas in Korea: A Retrospective Study.

Endocrinol Metab (Seoul) 2021 Jun 10. Epub 2021 Jun 10.

Department of Internal Medicine, Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.

Background: We aimed to evaluate the clinicopathological features and biological behaviors of Korean thyroid cancer patients with rare variants of papillary thyroid carcinoma (PTC) to address the ambiguity regarding the prognostic consequences of these variants.

Methods: We retrospectively reviewed the medical records of 5,496 patients who underwent thyroid surgery for PTC, between January and December 2012, in nine tertiary hospitals. Rare PTC variants included tall cell (TCV), columnar cell (CCV), diffuse sclerosing (DSV), cribriform-morular (CMV), solid (SV), hobnail, and Warthin-like variants. Read More

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Pillar[6]quinone: facile synthesis, crystal structures and electrochemical properties.

Chem Commun (Camb) 2021 Jun 9. Epub 2021 Jun 9.

Department of Chemical Science and Engineering, School of Materials and Chemical Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8502, Japan. and PRESTO, Japan Science and Technology Agency (JST), 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan.

A novel electron-deficient macrocycle, pillar[6]quinone (P[Q]6), has been synthesized for the first time by both chemical and electrochemical oxidation of pillar[6]arene, showing clear hexagonal columnar stacking in the solid state. Cathodic voltammetric studies of P[Q]6 revealed that three electrons are injected first, followed by stepwise one-electron reductions. Read More

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Monkey V1 epidural field potentials provide detailed information about stimulus location, size, shape, and color.

Commun Biol 2021 Jun 7;4(1):690. Epub 2021 Jun 7.

Brain Research Institute, Center for Cognitive Science, University of Bremen, Bremen, Germany.

Brain signal recordings with epidural microarrays constitute a low-invasive approach for recording distributed neuronal signals. Epidural field potentials (EFPs) may serve as a safe and highly beneficial signal source for a variety of research questions arising from both basic and applied neuroscience. A wider use of these signals, however, is constrained by a lack of data on their specific information content. Read More

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HOXA13 in etiology and oncogenic potential of Barrett's esophagus.

Nat Commun 2021 06 7;12(1):3354. Epub 2021 Jun 7.

Department of Gastroenterology and Hepatology, Erasmus MC - University Medical Center Rotterdam, Rotterdam, The Netherlands.

Barrett's esophagus in gastrointestinal reflux patients constitutes a columnar epithelium with distal characteristics, prone to progress to esophageal adenocarcinoma. HOX genes are known mediators of position-dependent morphology. Here we show HOX collinearity in the adult gut while Barrett's esophagus shows high HOXA13 expression in stem cells and their progeny. Read More

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Primary Mucinous Adenocarcinoma of the Seminal Vesicle Associated with Intestinal Metaplasia: A Radiation-Induced Tumor?

Histopathology 2021 Jun 7. Epub 2021 Jun 7.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Primary adenocarcinoma of the seminal vesicle is very rare, with fewer than one hundred well-documented cases reported in the literature (1). These tumors have variable microscopic appearances, including cases with hobnail, polygonal and columnar neoplastic cells arranged in diverse architectural patterns (1). We recently received a radical cystoprostatectomy specimen from a 74-year-old patient with biopsy-proven muscle-invasive urothelial carcinoma. Read More

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A conductive metal-organic framework photoanode.

Chem Sci 2020 Aug 27;11(35):9593-9603. Epub 2020 Aug 27.

Department of Chemistry and Yale Energy Sciences Institute, Yale University New Haven Connecticut 06520-8107 USA

We report the development of photosensitizing arrays based on conductive metal-organic frameworks (MOFs) that enable light harvesting and efficient charge separation. ZnTTFTB (TTFTB = tetrathiafulvalene tetrabenzoate) MOFs are deposited directly onto TiO photoanodes and structurally characterized by pXRD and EXAFS measurements. Photoinduced interfacial charge transfer dynamics are investigated by combining time-resolved THz spectroscopy and quantum dynamics simulations. Read More

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Hybrid stomach-intestinal chromatin states underlie human Barrett's metaplasia.

Gastroenterology 2021 Jun 3. Epub 2021 Jun 3.

Department of Medical Oncology and Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address:

Background & Aims: Tissue metaplasia is uncommon in adults because established cis-element programs resist rewiring. In Barrett's esophagus, the distal esophageal mucosa acquires predominantly intestinal character, with notable gastric features, and is predisposed to develop invasive cancers. We sought to understand the chromatin underpinnings of Barrett's metaplasia and why it commonly displays simultaneous gastric and intestinal properties. Read More

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Molecular perspective concerning fluoride and arsenic mediated disorders on epididymal maturation of spermatozoa: A concise review.

Hum Exp Toxicol 2021 Jun 4:9603271211021474. Epub 2021 Jun 4.

568916Department of Life Sciences, Presidency University, Kolkata, West Bengal, India.

Epididymis is a complex tubular structure of male reproductive system where spermatozoa undergo maturation and gain the fertilizing ability. Epididymal pseudostratified columnar epithelium with different cell types play imperative role by their secretory properties and enrich the luminal microenvironment necessary for achieving spermatozoal motility. During epididymal transit several secretory proteins like P26h, SPAG11, HSPD1 and many others are deposited on spermatozoal surface. Read More

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Characterization of the rabbit conjunctiva: Effects of sulfur mustard.

Exp Mol Pathol 2021 Jun 1;121:104656. Epub 2021 Jun 1.

Department of Environmental and Occupational Health and Justice, Rutgers University School of Public Health, Piscataway, NJ 08854, United States.

Sulfur mustard (SM; bis (2-chloroethyl) sulfide) is a potent vesicant which causes irritation of the conjunctiva and damage to the cornea. In the present studies, we characterized the ocular effects of SM in New Zealand white rabbits. Within one day of exposure to SM, edema and hazing of the cornea were observed, followed by neovascularization which persisted for at least 28 days. Read More

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[Clinicopathological features of gastric adenocarcinoma with enteroblastic differentiation: a report of twelve cases].

Zhonghua Bing Li Xue Za Zhi 2021 Jun;50(6):626-631

Provincial Clinical Medical College of Fujian Medical University, Department of Pathology, Fujian Provincial Hospital, Fuzhou 350001, China.

To investigate the clinicopathological features, immunophenotype, diagnosis and differential diagnosis of gastric adenocarcinoma with enteroblastic differentiation (GAED). Twelve cases of GAED diagnosed in Fujian Provincial Hospital from August 2019 to August 2020 were collected. HE staining, immunohistochemistry and HER2 gene amplification were evaluated. Read More

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Quasi-Static Tensile Properties of Unalloyed Copper Produced by Electron Beam Powder Bed Fusion Additive Manufacturing.

Materials (Basel) 2021 May 29;14(11). Epub 2021 May 29.

Center for Additive Manufacturing and Logistics, Fitts-Woolard Hall, North Carolina State University, Raleigh, NC 27606, USA.

Mechanical properties of powder bed fusion processed unalloyed copper are reported majorly in the as-fabricated condition, and the effect of post-processes, common to additive manufacturing, is not well documented. In this study, mechanical properties of unalloyed copper processed by electron beam powder bed fusion are characterized via room temperature quasi-static uniaxial tensile test and Vickers microhardness. Tensile samples were extracted both perpendicular and parallel to the build direction and assigned to three different conditions: as-fabricated, hot isostatic pressing (HIP), and vacuum annealing. Read More

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Synthesis of Copper Nitride Layers by the Pulsed Magnetron Sputtering Method Carried out under Various Operating Conditions.

Materials (Basel) 2021 May 20;14(10). Epub 2021 May 20.

Division of Surface Engineering, Faculty of Materials Science and Engineering, Warsaw University of Technology, 00-661 Warsaw, Poland.

Copper nitride shows various properties that depend on the structure of the material and is influenced by the change in technical parameters. In the present work, Cu-N layers were synthesized using the pulsed magnetron sputtering method. The synthesis was performed under different operating conditions: direct current (DC) or alternating current (AC) power supply, and various atmospheres: pure Ar and a mixture of Ar + N. Read More

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Effect of the Helium Background Gas Pressure on the Structural and Optoelectronic Properties of Pulsed-Laser-Deposited PbS Thin Films.

Nanomaterials (Basel) 2021 May 11;11(5). Epub 2021 May 11.

Centre Énergie Matériaux et Télécommunications (INRS-EMT), Institut National de la Recherche Scientifique (INRS), 1650 Boulevard Lionel Boulet, Varennes, QC J3X 1S2, Canada.

This work focuses on the dependence of the features of PbS films deposited by pulsed laser deposition (PLD) subsequent to the variation of the background pressure of helium (P). The morphology of the PLD-PbS films changes from a densely packed and almost featureless structure to a columnar and porous one as the He pressure increases. The average crystallite size related to the (111) preferred orientation increases up to 20 nm for P ≥ 300 mTorr. Read More

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Liquid Crystals Based on the -Phenylpyridinium Cation-Mesomorphism and the Effect of the Anion.

Molecules 2021 May 1;26(9). Epub 2021 May 1.

Department of Chemistry, University of York, Heslington, York YO10 5DD, UK.

Families of symmetric, ionic, tetracatenar mesogens are described based on a rigid, -phenylpyridinium core, prepared as their triflimide, octyl sulfate and dodecyl sulfate salts for a range of terminal chain lengths. The mesomorphism of the individual series is described before a comparison is drawn between the different families and then more broadly with (i) neutral tetracatenar materials and (ii) related bis(3,4-dialkoxystilbazole)silver(I) salts. For the octyl and dodecyl sulfates and the related triflates reported earlier, a SmA phase is seen at shorter chain lengths, giving way to a Col phase as the terminal chain lengthens. Read More

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Morphological examination of the accessory sex glands of the Barki bucks (Capra hircus).

Folia Morphol (Warsz) 2021 Jun 1. Epub 2021 Jun 1.

Department of Histology and Cytology, Faculty of Veterinary Medicine, Alexandria University, Egypt.

The present investigation was prepared to describe the accessory sex glands of the Barki bucks grossly and by light microscopy. There are four sex glands: ampullary, vesicular, prostate, and bulbourethral. The ampullary gland is an enlargement of the terminal part of the ductus deferens, its glandular part has branched tubuloalveolar glands, and its secretory alveoli lined with a pseudo-stratified epithelium composed of cuboidal to columnar cells. Read More

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Transition from horizontal expansion to vertical growth in the oyster prismatic layer.

Biochem Biophys Res Commun 2021 Jul 28;563:47-53. Epub 2021 May 28.

Protein Science Laboratory of the Ministry of Education, School of Life Science, Tsinghua University, Beijing, 100084, China; Department of Biotechnology and Biomedicine, Yangtze Delta Region Institute of Tsinghua University, Jiaxing, Zhejiang Province, 314006, China. Electronic address:

Biomimetic materials inspired by biominerals have substantial applications in various fields. The prismatic layer of bivalve molluscs has extraordinary flexibility compared to inorganic CaCO. Previous studies showed that in the early stage, minerals expanded horizontally and formed prism domains as a Voronoi division, while the evolution of the mature prisms were thermodynamically driven, which was similar to grain growth. Read More

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Histological, histochemical and energy disorders caused by R-limonene on Aedes aegypti L. larvae (Diptera: Culicidae).

Acta Trop 2021 May 28;221:105987. Epub 2021 May 28.

Department of Morphology and Animal Physiology, Federal Rural University of Pernambuco, Av. Dom Manoel de Medeiros s/n, Dois Irmãos, 52171-900 Recife, PE, Brazil.

The study evaluated the effects of R-limonene, in sublethal concentration, on the histology, histochemistry, biochemistry, and carbohydrates and proteins levels in the third instar Aedes aegypti larvae. The R-limonene (LC50 of 27 ppm) and control groups were analyzed 12 and 24 h after the beginning of treatments. The midgut of the control larvae was composed of cylindrical and elongated cells with a spherical and central nucleus and regenerative cells with a pyramidal shape. Read More

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Bronchogenic cyst of the floor of mouth combined with ankyloglossia: an extremely rare presentation of rare anomaly.

J Surg Case Rep 2021 May 27;2021(5):rjab211. Epub 2021 May 27.

Division of Plastic and Reconstructive Surgery, Department of Surgery, Phramongkutklao Hospital and Phramongkutklao College of Medicine, Bangkok, Thailand.

Bronchogenic cyst (BC), cyst lined by respiratory epithelium, is uncommon congenital anomaly of bronchial tree. Intraoral BC is extremely rare lesions. Here, we report the unusual presentation of 2-year-old boy with symptomatic cystic lesion at floor of month combined with ankyloglossia. Read More

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Identification and treatment of a cervical sinus tract in a patient with 10 years of infertility.

Fertil Steril 2021 May 27. Epub 2021 May 27.

Department of Gynecology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China. Electronic address:

Objective: To introduce a special case of endometrial cavity fluid (ECF), highlighting the application of hysteroscopy and laparoscopic surgical techniques in the treatment of cervical sinus tract.

Design: Narrated video featuring the diagnosis and surgical management of a case of recurrent ECF. Informed consent was obtained from the patient, and approval was granted by the ethics committee of the First Affiliated Hospital of the Wenzhou Medical University. Read More

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Epidemiology of Barrett's Esophagus and Esophageal Carcinoma.

Surg Clin North Am 2021 Jun;101(3):381-389

To care and treat patients with esophageal cancer, one must first understand the epidemiology of Barrett's esophagus (BE). BE is defined as the intestinal metaplasia occurring within the esophagus from normal squamous epithelium to abnormal specialized columnar epithelium. BE, while first described by Allison in 1948, was attributed to Norman Barrett in 1950, who reported a case of chronic peptic ulcer in the lower esophagus that was covered by columnar epithelium. Read More

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Mesenchymal-to-epithelial transitions require tissue-specific interactions with distinct laminins.

J Cell Biol 2021 Aug 28;220(8). Epub 2021 May 28.

Department of Biomedical Science and Bateson Centre, The University of Sheffield, Sheffield, UK.

Mesenchymal-to-epithelial transition (MET) converts cells from migratory mesenchymal to polarized epithelial states. Despite its importance for both normal and pathological processes, very little is known about the regulation of MET in vivo. Here we exploit midgut morphogenesis in Drosophila melanogaster to investigate the mechanisms underlying MET. Read More

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Sudden outbreak of metastatic intestinal adenocarcinoma in rainbow trout Oncorhynchus mykiss.

Dis Aquat Organ 2021 May 27;144:237-244. Epub 2021 May 27.

Institute of Pathology, Wild Animals, Fish and Bees, Veterinary Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.

Intestinal adenocarcinomas are uncommon in fishes. To date, they have been reported in zebrafish Danio rerio, blue gularis Fundulopanchax sjostedti, koi carp Cyprinus carpio koi, Atlantic salmon Salmo salar and rainbow trout Oncorhynchus mykiss. Metastases are even rarer and have been observed so far at very low prevalence, only in feed-induced adenocarcinoma in Atlantic salmon and rainbow trout. Read More

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Cardiac Myxoma: Typical Presentation but Unusual Histology.

Case Rep Med 2021 4;2021:6611579. Epub 2021 May 4.

Department of Cardiothoracic Surgery, College of Medicine, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.

Cardiac myxoma, a benign heart tumor, is the most common primary tumor of the heart. Glandular differentiation within these tumors is rare, occurring in approximately 3% of all cardiac myxomas. Its presence can complicate the diagnostic process. Read More

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Vital Role of Gene in Ammonia Detoxification and the Association Between its SNPs and Ammonia Tolerance in .

Front Physiol 2021 5;12:664804. Epub 2021 May 5.

Ninghai Institute of Mariculture Breeding and Seed Industry, Zhejiang Wanli University, Ninghai, China.

Increasing evidence has revealed accumulated ammonia will cause adverse effects on the growth, reproduction, and survival of aquatic animals. As a marine benthic mollusk, the razor clam shows better growth and survival under high ammonia nitrogen environment. However, little is known about its adaptation mechanisms to high ammonia stress in an integrated mariculture system. Read More

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A Müllerian cyst in a male adolescent: a case report and literature review.

Jun He Kaifa Tang

J Int Med Res 2021 May;49(5):3000605211016663

Department of Urology, 74720The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.

Müllerian duct cyst is a congenital anomaly that originates from an abnormality in the degradation of the Müllerian system and remnants of the Müllerian duct. Müllerian cyst is rarely reported in male adolescents younger than 18 years of age. In this case report, a 17-year-old male adolescent presented with a scrotal mass of 6 years' duration. Read More

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Chromonic liquid crystals and packing configurations of bacteriophage viruses.

Philos Trans A Math Phys Eng Sci 2021 Jul 24;379(2201):20200111. Epub 2021 May 24.

Department of Mathematics, MSB, 2150, University of California Davis, One Shields Avenue, Davis, CA 95616, USA.

We study equilibrium configurations of hexagonal columnar liquid crystals in the context of characterizing packing structures of bacteriophage viruses in a protein capsid. These are viruses that infect bacteria and are currently the focus of intense research efforts, with the goal of finding new therapies for bacteria-resistant antibiotics. The energy that we propose consists of the Oseen-Frank free energy of nematic liquid crystals that penalizes bending of the columnar directions, in addition to the cross-sectional elastic energy accounting for distortions of the transverse hexagonal structure; we also consider the isotropic contribution of the core and the energy of the unknown interface between the outer ordered region of the capsid and the inner disordered core. Read More

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