J Clin Rheumatol 2021 Mar 25. Epub 2021 Mar 25.
From the Sealy Center on Aging, University of Texas Medical Branch at Galveston, Galveston, TX Division of Rheumatology, Complejo Hospitalario "Ruiz y Páez," Universidad de Oriente, Centro Nacional de Enfermedades Reumáticas, Ciudad Bolívar, Venezuela Grupo de Inmunología Celular e Inmunogenética, Instituto de Investigaciones Médicas, Universidad de Antioquia, Medellin, Colombia.
Abstract: Antibodies are a fundamental tool to fight infections but are intrinsically built as a double-edged sword. One side recognizes the microbial antigen, and the other gives a call to arms to fight infection by recruiting immune cells and triggering inflammation. A balanced immune response must combine a potent neutralizing antibody and a swift disposal of the invading agent by innate immune cells with the least tissue damage possible. Read More