1,386 results match your criteria colombia venezuela

Virtual journal club during the pandemic: a valuable learning tool.

Int J Gynecol Cancer 2021 May 14. Epub 2021 May 14.

Department of Gynecology Oncology, Instituto Nacional de Cancerología, Bogotá, Colombia

View Article and Full-Text PDF

The paradox of haematopoietic cell transplant in Latin America.

Bone Marrow Transplant 2021 May 13. Epub 2021 May 13.

FUNDALEU, Buenos Aires, Argentina.

Hematopoietic cells transplants are technically complex and expensive imposing a huge burden on health care systems, especially those in developing countries and regions. In 2017 > 4500 transplants were done in 13 Latin American countries with established transplant programmes. We interrogated data on transplant rate, cost, funding source, hospital type, Gini coefficient and the United Nations Development Programme Inequality-Adjusted Human Development Index to determine co-variates associated with transplant development. Read More

View Article and Full-Text PDF

Safe resumption of elective surgery: a Latin American proposal.

Braz J Anesthesiol 2021 May 10. Epub 2021 May 10.

Anesthesiologist Policlínica Las Mercedes, Chair Education Committee CLASA, Caracas, Venezuela.

View Article and Full-Text PDF

International registry of dermatological manifestations secondary to COVID-19 infection in 347 Hispanic patients from 25 countries.

Int J Dermatol 2021 May 8. Epub 2021 May 8.

Departamento de Dermatología, Instituto de Biomedicina, Universidad Central de Venezuela, Hospital Vargas Clínica El Ávila, Caracas, Venezuela.

Background: The infection by coronavirus disease 2019 (COVID-19) has been associated with multiple cutaneous manifestations, although characterization of them in Hispanic patients with darker skin phototypes is lacking. The objective of this study is to characterize the clinical dermatological manifestations associated with COVID-19 infection in cases with few or without general symptoms in patients from Latin America.

Methods: Cross-sectional study using a questionnaire that was made for health professionals (physicians with a specialty in dermatology) to investigate dermatological lesions associated with COVID-19 infection in patients from 25 countries of Latin America. Read More

View Article and Full-Text PDF

Synthesis, crystal structure, Hirshfeld surface analysis and energy framework calculations of -3,7,9,9-tetra-methyl-10-(prop-2-yn-1-yl)-1,2,3,4,4a,9,9a,10-octa-hydro-acridine.

Acta Crystallogr E Crystallogr Commun 2021 Mar 5;77(Pt 3):226-232. Epub 2021 Feb 5.

Laboratorio de Cristalografía-LNDRX, Departamento de Química, Facultad de Ciencias, Universidad de los Andes, Mérida, Venezuela.

The title heterocyclic compound, CHN, has been prepared in good yield (72%) a BiCl-catalyzed cationic Povarov reaction between -propargyl-4-methyl-aniline and (±)-citronellal. The X-ray single-crystal study indicates that the structure consists of mol-ecules connected by C-H⋯π contacts to produce chains, which pack in a sandwich-herringbone fashion along the -axis direction. Hirshfeld surface analysis indicates that H⋯H inter-actions dominate by contributing 79. Read More

View Article and Full-Text PDF

Palliative medicine specialization in Latin America: A comparative analysis.

J Pain Symptom Manage 2021 Apr 29. Epub 2021 Apr 29.

Dieter Scheffner Center for Medical Education and Educational Research, Dean´s Office of Study Affairs, Charité - Universitätsmedizin Berlin.

Background: Formal recognition of palliative medicine as a specialty has been one of the main drivers in the development of palliative care.

Aim: To provide a comparative, comprehensive overview on the status of palliative medicine as medical specialty across Latin America.

Method: We conducted a comparative study of 19 Latin American countries. Read More

View Article and Full-Text PDF

Accelerometer-Measured Daily Step Counts and Adiposity Indicators among Latin American Adults: A Multi-Country Study.

Int J Environ Res Public Health 2021 Apr 27;18(9). Epub 2021 Apr 27.

Centro de Excelencia em Nutrição e Dificuldades Alimentaes (CENDA), Instituto Pensi, Fundação José Luiz Egydio Setubal, Hospital Infantil Sabará, São Paulo 01228-200, Brazil.

The aim of the present study was to examine the sex-related associations between accelerometer-measured daily step counts and adiposity indicators in adults from eight Latin American countries. We analyzed data from 2524 adults (aged 18-65 years) from the Latin American Study of Nutrition and Health. Device-measured daily step counts were measured by accelerometers (ActiGraph GT3X). Read More

View Article and Full-Text PDF

Evaluation of the diagnostic performance of nine commercial RT-PCR kits for the detection of SARS-CoV-2 in Colombia.

J Med Virol 2021 Apr 29. Epub 2021 Apr 29.

Centro de Investigaciones en Microbiología y Biotecnología-UR (CIMBIUR), Facultad de Ciencias Naturales, Universidad del Rosario, Bogotá, Colombia.

The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has led to the design and development of multiple reverse-transcription polymerase chain reaction kits aimed to facilitate the rapid scale-up of molecular testing for massive screening. We evaluated the diagnostic performance of nine commercial kits, which showed optimal performance and high discriminatory power. However, we observed differences in terms of sensitivity, specificity, and E gene Ct Values and discuss these results in light of the influence of SARS-CoV-2 genetic variability and its potential impact in current molecular diagnostic assays. Read More

View Article and Full-Text PDF

The 2-year rodent bioassay in drug and chemical carcinogenicity testing: Panorama of its concordance, utility, configuration, and provisional regulatory role.

J Pharmacol Toxicol Methods 2021 Apr 24:107070. Epub 2021 Apr 24.

Laboratory of Neuropeptides, Institute of Pharmaceutical Research, School of Pharmacy, Universidad Central de Venezuela, Caracas, Venezuela.

For several intended uses of chemicals, the 2-year rodent bioassay (RCB) has been the benchmark method to screen the carcinogenicity to humans of substances (according to the hazard identification sphere). Despite the ongoing controversy around this traditional testing, the RCB is still in force and being used by stakeholders. After assembling the RCB's ability to forecast the carcinogenicity to humans of substances, the current review aimed to provide a discussion on the RCB's (1) sensitivity and specificity; (2) utility; (3) configuration, and (4) provisional role in the regulatory practice. Read More

View Article and Full-Text PDF

A review of emCryphocricos/em Signoret, 1850 (Naucoridae: Cryphocricinae) with descriptions of three new species.

Robert W Sites

Zootaxa 2021 Apr 14;4958(1):zootaxa.4958.1.7. Epub 2021 Apr 14.

Enns Entomology Museum University of Missouri Columbia, Missouri 65211 USA.

The genus Cryphocricos Signoret, 1850 was recently determined in a molecular phylogeny to be distantly related to other taxa of the subfamily Cryphocricinae to the extent that it is now once again the sole member of the subfamily. This exclusively New World group of aquatic bugs lives in fast and usually turbulent current and respires by means of a plastron. Efforts to identify morphological features to distinguish among the species have largely fallen short, and some species have been established based on features that exhibit a high degree of intraspecific variation overlapping those of other species. Read More

View Article and Full-Text PDF

Lack of experience is a main cause of maternal death in placenta accreta spectrum patients.

Acta Obstet Gynecol Scand 2021 Apr 25. Epub 2021 Apr 25.

Clínica de Espectro de Acretismo Placentario, Fundación Valle del Lili, Cali, Colombia.

Introduction: Placenta accreta spectrum (PAS) is a serious condition with a mortality as high as 7%. However, the factors associated with this type of death have not been adequately described, with an almost total lack of publications analyzing the determining factors of death in this disease. The aim of our work is to describe the causes of death related to PAS and to analyze the associated diagnosis and treatment problems. Read More

View Article and Full-Text PDF

The numerical probability of carcinogenicity to humans of some antimicrobials: Nitro-monoaromatics (including 5-nitrofurans and 5-nitroimidazoles), quinoxaline-1,4-dioxides (including carbadox), and chloramphenicol.

Toxicol In Vitro 2021 Apr 20;75:105172. Epub 2021 Apr 20.

Institute of Pharmaceutical Research, Faculty of Pharmacy, Universidad Central de Venezuela, Caracas, Venezuela.

Many substances are already tested in the long-term rodent bioassay (RCB). Nonetheless, statements such as the following are common in the regulatory literature: "the significance of the carcinogenicity findings in rodents relative to the therapeutic use of drugs in humans is unknown." (U. Read More

View Article and Full-Text PDF

Ibero-Panamerican Federation of Periodontics Delphi study on the trends in Diagnosis and Treatment of Peri-implant Diseases and Conditions: A Latin American consensus.

J Periodontol 2021 Apr 14. Epub 2021 Apr 14.

ETEP (Etiology and Therapy of Periodontal and Peri-Implant Diseases) Research Group, University Complutense.

Background: The social diversity, heterogeneous culture and inherent economic inequality factors in Latin America (LA) justify conducting a comprehensive analysis on the current status and future trends of peri-implant diseases and conditions. Thus, the aim of this Delphi study was to predict the future trends in the diagnosis and treatment of peri-implant diseases and conditions in LA countries for the year 2030.

Materials And Methods: A Latin American steering committee and group of experts in implant dentistry validated a questionnaire including 64 questions divided into 8 sections. Read More

View Article and Full-Text PDF

Antibodies: Friends, Foes, or Both? Lessons From COVID-19 for the Rheumatologist.

J Clin Rheumatol 2021 Mar 25. Epub 2021 Mar 25.

From the Sealy Center on Aging, University of Texas Medical Branch at Galveston, Galveston, TX Division of Rheumatology, Complejo Hospitalario "Ruiz y Páez," Universidad de Oriente, Centro Nacional de Enfermedades Reumáticas, Ciudad Bolívar, Venezuela Grupo de Inmunología Celular e Inmunogenética, Instituto de Investigaciones Médicas, Universidad de Antioquia, Medellin, Colombia.

Abstract: Antibodies are a fundamental tool to fight infections but are intrinsically built as a double-edged sword. One side recognizes the microbial antigen, and the other gives a call to arms to fight infection by recruiting immune cells and triggering inflammation. A balanced immune response must combine a potent neutralizing antibody and a swift disposal of the invading agent by innate immune cells with the least tissue damage possible. Read More

View Article and Full-Text PDF

Contribution of food groups to energy, grams and nutrients-to-limit: the Latin American Study of Nutrition and Health/Estudio Latino Americano de Nutrición y Salud (ELANS).

Public Health Nutr 2021 Apr 12:1-13. Epub 2021 Apr 12.

Center for Excellence in Nutrition and Feeding Difficulties, PENSI Institute, Sabara's Children Hospital, São Paulo, Brazil.

Objective: To quantify the energy, nutrients-to-limit and total gram amount consumed and identify their top food sources consumed by Latin Americans.

Design: Data from the Latin American Study of Nutrition and Health (ELANS).

Setting: ELANS is a cross-sectional study representative of eight Latin American countries: Argentina, Brazil, Chile, Colombia, Costa Rica, Ecuador, Peru and Venezuela. Read More

View Article and Full-Text PDF

Management practices for placenta accreta spectrum patients: a Latin American hospital survey.

J Matern Fetal Neonatal Med 2021 Apr 11:1-8. Epub 2021 Apr 11.

Maternidad Oroño, Rosario, Argentina.

Introduction: Placenta accreta spectrum (PAS) causes severe morbidity and can result in maternal death. It must be managed in specialized centers with interdisciplinary groups, but few publications have described the usual management within a specific geographic region. We intend to describe the usual approach for PAS in reference centers in Latin America. Read More

View Article and Full-Text PDF

US Obesity Mortality Trends and Associated Noncommunicable Diseases Contributing Conditions Among White, Black, and Hispanic Individuals by Age from 1999 to 2017.

SN Compr Clin Med 2021 Apr 5:1-10. Epub 2021 Apr 5.

Public Health Developments Organization, Washington, DC USA.

This study aims to assess the effect of obesity as an underlying cause of death in association with four main noncommunicable diseases (NCDs) as contributing causes of mortality on the age of death in White, Black, and Hispanic individuals in the USA. To estimate mortality hazard ratios, we ran a Cox regression on the US National Center for Health Statistics mortality integrated datasets from 1999 to 2017, which included almost 48 million cases. The variable in the model was the age of death in years as a proxy for time to death. Read More

View Article and Full-Text PDF

A metric for spatially explicit contributions to science-based species targets.

Nat Ecol Evol 2021 Apr 8. Epub 2021 Apr 8.

IUCN, Cambridge, UK.

The Convention on Biological Diversity's post-2020 Global Biodiversity Framework will probably include a goal to stabilize and restore the status of species. Its delivery would be facilitated by making the actions required to halt and reverse species loss spatially explicit. Here, we develop a species threat abatement and restoration (STAR) metric that is scalable across species, threats and geographies. Read More

View Article and Full-Text PDF

Overexpression of A Gene Increases Ciprofloxacin Resistance in .

Int J Microbiol 2021 22;2021:6689186. Epub 2021 Mar 22.

Grupo de Investigación en Microbiología, Industria y Ambiente (GIMIA), Facultad de Ciencias Básicas, Universidad Santiago de Cali, Cali, Colombia.

Fluoroquinolones (FQs) are antibiotics useful in the treatment of drug-resistant tuberculosis, but FQ-resistant mutants can be selected rapidly. Although mutations in the DNA gyrase are the principal cause of this resistance, pentapeptide proteins have been found to confer low-level FQ resistance in Gram-negative bacteria. MfpA is a pentapeptide repeat protein conserved in mycobacterial chromosomes, where it is adjacent to a group of four highly conserved genes termed a . Read More

View Article and Full-Text PDF

Concerns about influenza H5N8 outbreaks in humans and birds: Facing the next airborne pandemic?

Travel Med Infect Dis 2021 May-Jun;41:102054. Epub 2021 Apr 3.

Department of Pathology, Molecular and Cell-Based Medicine, Laboratory of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Instituto de Investigaciones Biomédicas IDB/Incubadora Venezolana de la Ciencia, Barquisimeto, Venezuela.

View Article and Full-Text PDF

Perception of COVID-19 Vaccination Amongst Physicians in Colombia.

Vaccines (Basel) 2021 Mar 19;9(3). Epub 2021 Mar 19.

Latin American Network of Coronavirus Disease 2019 Research (LANCOVID), Pereira, Risaralda 660003, Colombia.

: The SARS-CoV-2/COVID-19 pandemic has triggered the need to develop rapidly effective and safe vaccines to prevent infection, particularly in those at-risk populations such as medical personnel. This study's objective was to assess the perception of COVID-19 vaccination amongst Colombian physicians featuring two different scenarios of COVID-19 vaccination. : A cross-sectional analytical study was carried out through an online survey directed at medical staff in several cities in Colombia. Read More

View Article and Full-Text PDF

Phylogenomic Evidence of Reinfection and Persistence of SARS-CoV-2: First Report from Colombia.

Vaccines (Basel) 2021 Mar 19;9(3). Epub 2021 Mar 19.

Icahn School of Medicine at Mount Sinai, New York, NY 10001, USA.

The continuing evolution of SARS-CoV-2 and the emergence of novel variants have raised concerns about possible reinfection events and potential changes in the coronavirus disease 2019 (COVID-19) transmission dynamics. Utilizing Oxford Nanopore technologies, we sequenced paired samples of three patients with positive RT-PCR results in a 1-2-month window period, and subsequent phylogenetics and genetic polymorphism analysis of these genomes was performed. Herein, we report, for the first time, genomic evidence of one case of reinfection in Colombia, exhibiting different SARS-CoV-2 lineage classifications between samples (B. Read More

View Article and Full-Text PDF

Amazon tree dominance across forest strata.

Nat Ecol Evol 2021 Apr 1. Epub 2021 Apr 1.

INRA, UMR EcoFoG, AgroParisTech, CNRS, CIRAD, Université des Antilles, Université de Guyane, Kourou, French Guiana.

The forests of Amazonia are among the most biodiverse plant communities on Earth. Given the immediate threats posed by climate and land-use change, an improved understanding of how this extraordinary biodiversity is spatially organized is urgently required to develop effective conservation strategies. Most Amazonian tree species are extremely rare but a few are common across the region. Read More

View Article and Full-Text PDF

Simple anthropometry-based calculations to monitor body composition in athletes: Scoping review and reference values.

Nutr Health 2021 Apr 1:2601060211002941. Epub 2021 Apr 1.

Research Division, DBSS International, Colombia.

Background: Kinanthropometry offers to exercise and health professionals a standardized procedure of acquiring surface anatomical measurements that might be used to track changes in body composition.

Aim: To describe simple anthropometric indices to monitor body composition changes in amateur and elite athletes, and to provide reference values during the competition phase.

Methods: A search of articles indexed in PubMed/MEDLINE, ScienceDirect, Cochrane, and SciELO databases using the string . Read More

View Article and Full-Text PDF

Chikungunya and the Heart.

Cardiology 2021 Mar 31:1-11. Epub 2021 Mar 31.

Division of Cardiology, Kingston Health Science Center, Queen's University, Kingston, Ontario, Canada.

Introduction: Neglected tropical diseases are a group of communicable diseases that occur in tropical and subtropical conditions and are closely related to poverty and inadequate sanitation conditions. Among these entities, chikungunya remains one of the most widely spread diseases. Although the main symptoms are related to a febrile syndrome, cardiovascular (CV) involvement has been reported, with short- and long-term implications. Read More

View Article and Full-Text PDF

The numerical probability of carcinogenicity to humans of some pharmaceutical drugs: Alkylating agents, topoisomerase inhibitors or poisons, and DNA intercalators.

Fundam Clin Pharmacol 2021 Mar 26. Epub 2021 Mar 26.

Faculty of Pharmacy, Institute of Pharmaceutical Research, Universidad Central de Venezuela, Caracas, Venezuela.

The nonclinical branch of regulatory pharmacology has traditionally relied on the sensitivity and specificity of regulatorily recommended bioassays. Nonetheless, any predictive testing (eg, safety pharmacology) with less than 100% sensitivity or 100% specificity is prone to deliver false positive or negative results (namely, outcomes discordant to the clinical gold standard). It was recently suggested that the statistics-based and regulatory pertinent "predictive values approach" (PVA) might help to reach a more predictive use of preclinical testing data. Read More

View Article and Full-Text PDF

Latitude dictates plant diversity effects on instream decomposition.

Sci Adv 2021 Mar 26;7(13). Epub 2021 Mar 26.

Marine Institute, Furnace, Newport, Ireland.

Running waters contribute substantially to global carbon fluxes through decomposition of terrestrial plant litter by aquatic microorganisms and detritivores. Diversity of this litter may influence instream decomposition globally in ways that are not yet understood. We investigated latitudinal differences in decomposition of litter mixtures of low and high functional diversity in 40 streams on 6 continents and spanning 113° of latitude. Read More

View Article and Full-Text PDF

Metacyclogenesis of Trypanosoma cruzi in B. ferroae (Reduviidae: Triatominae) and feces infectivity under laboratory conditions

Biomedica 2021 03 19;41(1):179-186. Epub 2021 Mar 19.

Grupo de Investigaciones en Ciencias Básicas y Aplicadas para la Sostenibilidad, Facultad de Ciencias Exactas, Naturales y Agropecuarias, Universidad de Santander, Bucaramanga, Colombia.

Introduction: Belminus ferroae is a triatominae with entomophagous behavior. However, it may occasionally feed on vertebrates. Currently, there is no evidence of natural infection with Trypanosoma cruzi or the occurrence of metacyclogenesis in this species. Read More

View Article and Full-Text PDF