888,551 results match your criteria collected


Retrospective evaluation of gastrointestinal foreign bodies and presurgical predictors for enterectomy versus enterotomy in dogs (2013-2016): 82 cases.

J Vet Emerg Crit Care (San Antonio) 2021 Sep 23. Epub 2021 Sep 23.

Department of Clinical Studies, Matthew J. Ryan Veterinary Teaching Hospital, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Objective: To evaluate preoperative diagnostics in dogs with gastrointestinal foreign body (GIFB) obstruction and to identify clinical variables associated with the performance of simple enterotomy (EO) versus enterectomy (EC).

Design: Retrospective case control study from October 2013 to January 2016.

Setting: Veterinary Teaching Hospital. Read More

View Article and Full-Text PDF
September 2021

Clinical impact of NPM1-mutant molecular persistence after chemotherapy for acute myeloid leukemia.

Blood Adv 2021 Sep 23. Epub 2021 Sep 23.

Alfred Hospital and Monash University, Melbourne, Australia.

Monitoring of NPM1 mutant (mut) measurable residual disease (MRD) in acute myeloid leukemia (AML) has an established role in patients treated with intensive chemotherapy. The European LeukemiaNet has defined molecular persistence at low copy number (MP-LCN) as MRD transcript level <1-2% with <1-log change between any 2 positive samples collected after the end of treatment (EOT). As the clinical impact of MP-LCN is unknown, we sought to characterize outcomes in patients with persistent NPM1mut MRD after EOT and identify factors associated with disease progression. Read More

View Article and Full-Text PDF
September 2021

Clinicopathological and Prognostic Features of 67 Cases with Pulmonary Sarcomatoid Carcinoma: An 18-Year Single-Centre Experience.

Oncol Res Treat 2021 Sep 23:1-10. Epub 2021 Sep 23.

Department of Medical Oncology, Istanbul University Institute of Oncology, Istanbul, Turkey.

Introduction: Pulmonary sarcomatoid carcinoma (PSC) is a very rare subtype of non-small-cell lung cancer (NSCLC). It is frequently diagnosed in the advanced stage and is resistant to conventional chemotherapeutics. Due to the unique nature and rarity, we evaluated the epidemiological, clinicopathological, and survival data of PSC patients treated at our centre. Read More

View Article and Full-Text PDF
September 2021

Biomonitoring of 89 POPs in blood serum samples of Czech city policemen.

Environ Pollut 2021 Sep 10;291:118140. Epub 2021 Sep 10.

University of Chemistry and Technology, Prague, Faculty of Food and Biochemical Technology, Department of Food Analysis and Nutrition, Technicka 3, 166 28, Prague 6, Czech Republic. Electronic address:

In this biomonitoring study, we evaluated the concentrations of 8 polychlorinated biphenyls (PCBs), 11 organochlorinated pesticides (OCPs), 33 brominated flame retardants (BFRs), 7 novel brominated and chlorinated flame retardants (novel FRs) and 30 per- and polyfluoroalkylated substances (PFAS) in human serum samples (n = 274). A total of 89 persistent organic pollutants (POPs) were measured in blood serum samples of city policemen living in three large cities and their adjacent areas (Ostrava, Prague, and Ceske Budejovice) in the Czech Republic. All samples were collected during the year 2019 in two sampling periods (spring and autumn). Read More

View Article and Full-Text PDF
September 2021

The experiences of student nurses in a pandemic: A qualitative study.

Nurse Educ Pract 2021 Sep 11;56:103186. Epub 2021 Sep 11.

School of Health and Social Work, University of Hertfordshire College Lane, Hatfield, Hertfordshire AL10 9AB, United Kingdom. Electronic address:

Aim/objective: To record and learn from the experiences of students working on clinical placement in a pandemic.

Background: In March of 2020, final and second year student nurses in England were given the option to join the Covid-19 pandemic work-force, paid as high-level health care assistants.

Methods/design: Using qualitative methods and rapid analysis techniques, this study gathered the unique experiences of 16 final year students, from all fields of nursing at a University in the East of England, who chose to complete their final extended placement in a diverse range of clinical placements at the height of the first wave of the pandemic. Read More

View Article and Full-Text PDF
September 2021

Occurrence and exposure analysis of microplastic in the gut and muscle tissue of riverine fish in Kermanshah province of Iran.

Mar Pollut Bull 2021 Sep 20;173(Pt A):112915. Epub 2021 Sep 20.

Department of Environmental Health Engineering, Faculty of Health, Research Center for Environmental Determinants of Health (RCEDH), Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran. Electronic address:

This study aimed to determine the presence of MPs in the gut and muscle tissue of riverine fish collected from the Qarasu River, Kermanshah, Iran. The results highlighted that MPs were found in the gut and muscle of all fish species at an average abundance of 8.12 ± 4. Read More

View Article and Full-Text PDF
September 2021

Otolith mass asymmetry in three sparid fish species collected from the Iraqi waters.

Mar Pollut Bull 2021 Sep 20;173(Pt A):112968. Epub 2021 Sep 20.

University of South Bohemia, Faculty of Agriculture, Department of Animal Science, České Budějovice, Czech Republic.

Saccular otolith mass asymmetry is examined in three sparid fish species, Acanthopagrus bifasciatus, A. arabicus, and Sparidentex hasta collected from Khor Abdullah at the North Persian Gulf. This characteristic was computed as the disparity between the weight of the right and left otoliths divided by mean otolith weight in the three sparid species investigated. Read More

View Article and Full-Text PDF
September 2021

Overexpressed LINC00467 promotes the viability and proliferation yet inhibits apoptosis of gastric cancer cells via raising ITGB3 level.

Tissue Cell 2021 Sep 20;73:101644. Epub 2021 Sep 20.

Gastroenterology Department, The 3(rd) Affiliated Hospital of Chengdu Medical College, Pidu District People's Hospital, Chengdu, China. Electronic address:

Long non-coding RNA (lncRNA) LINC00467 plays a proto-oncogenic role in non-small cell lung cancer. However, its effect and modulatory mechanism in gastric cancer (GC) are unknown. Thereby, we elucidated the mechanism of LINC00467 in GC. Read More

View Article and Full-Text PDF
September 2021

Repercussions of clinical waste co-incineration in municipal solid waste incinerator during COVID-19 pandemic.

J Hazard Mater 2021 Sep 15;423(Pt B):127144. Epub 2021 Sep 15.

Institute of Waste Treatment & Reclamation, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China; Shanghai Institute of Pollution Control and Ecological Security, Shanghai 200092, China; Shanghai Engineering Research Center of Multi-source Solid Wastes Co-processing and Energy Utilization, Shanghai 200092, China.

During coronavirus disease 2019 pandemic, the exponential increase in clinical waste (CW) generation has caused immense burden to CW treatment facilities. Co-incineration of CW in municipal solid waste incinerator (MSWI) is an emergency treatment method. A material flow model was developed to estimate the change in feedstock characteristics and resulting acid gas emission under different CW co-incineration ratios. Read More

View Article and Full-Text PDF
September 2021

Investigation of the effects of restrictions applied on children during Covid-19 pandemic.

J Pediatr Nurs 2021 Sep 15;61:340-345. Epub 2021 Sep 15.

Department of Pediatric Nursing, Pamukkale University Faculty of Health Sciences, Pamukkale Üniversitesi Sağlık Bilimleri Fakültesi, Kınıklı Kampüsü, Denizli, Turkey. Electronic address:

Purpose: The objective of this study was to determine the effects of restrictions that have been imposed during the COVID-19 pandemic, and contact with a COVID-19 positive individual on children and the practices adopted by parents to help their children cope with these effects.

Design And Methods: The data for this descriptive study were collected through social media platforms. The study included 464 parents who have children between the ages of 3 and 18, use social media, and are willing to participate in the study. Read More

View Article and Full-Text PDF
September 2021

Novel viruses in hard ticks collected in the Republic of Korea unveiled by metagenomic high-throughput sequencing analysis.

Ticks Tick Borne Dis 2021 Sep 4;12(6):101820. Epub 2021 Sep 4.

Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, 21702, Maryland, USA.

Ticks are vectors of a wide range of zoonotic viruses of medical and veterinary importance. Recently, metagenomics studies demonstrated that they are also the source of potentially pathogenic novel viruses. During the period from 2015 to 2017, questing ticks were collected by dragging the vegetation from geographically distant locations in the Republic of Korea (ROK) and a target-independent high-throughput sequencing method was utilized to study their virome. Read More

View Article and Full-Text PDF
September 2021

User perspectives on the design and setup of lower limb mirror therapy equipment after stroke: a technical report.

Physiotherapy 2021 May 13;113:37-43. Epub 2021 May 13.

School of Health Sciences, University of East Anglia, UK; NIHR Brain Injury MedTech, UK.

Objectives: To co-design lower limb mirror therapy (MT) equipment and setup by working directly with stroke survivors and physiotherapists.

Design: Co-design approach through focus groups.

Participants: Twenty-six participants. Read More

View Article and Full-Text PDF

Deep learning analysis and age prediction from shoeprints.

Forensic Sci Int 2021 Aug 30;327:110987. Epub 2021 Aug 30.

Department of Electrical Engineering and Computer Science, Bond Life Sciences Center, University of Missouri, Columbia, MO, United States. Electronic address:

Human gaits are the patterns of limb movements which involve both the upper and lower body parts. These patterns in terms of step rate, gait speed, stance widening, stride, and bipedal forces are influenced by different factors including environmental (such as social, cultural, and behavioral traits) and physical changes (such as age and health status). These factors are reflected on the imprinted shoeprints generated with body forces, which in turn can be used to predict age, a problem not systematically addressed using any computational approach. Read More

View Article and Full-Text PDF

The parents are watching: Midwifery students' perceptions of how workplace bullying impacts mothers and babies.

Midwifery 2021 Sep 14;103:103144. Epub 2021 Sep 14.

School of Nursing, Midwifery and Social Sciences, CQUniversity Australia, QLD, Australia. Electronic address:

Problem: Bullying in the midwifery profession has been documented and the problem is now known to extend to the poor treatment of midwifery students. In nursing, research has shown that bullying in the clinical workplace can adversely impact on quality of care. To date, no research has explored whether the bullying of midwifery students has secondary impacts on the experiences and care of mothers, babies, and their support persons. Read More

View Article and Full-Text PDF
September 2021

LIF and bFGF enhanced chicken primordial follicle activation by Wnt/β-catenin pathway.

Theriogenology 2021 Sep 16;176:1-11. Epub 2021 Sep 16.

Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China. Electronic address:

The cytokines leukemia inhibitory factor (LIF) and basic fibroblast growth factor (bFGF) are closely related to the development of primordial follicles. In this study, the functions and correlation of LIF and bFGF in the development of chicken primordial follicles were examined, along with the signaling pathways including protein kinase B (AKT), extracellular regulated protein kinase (ERK) and Wnt/β-catenin signaling pathways. Ovarian tissues were collected from four-day-old chicks and incubated with LIF and bFGF alone or in combination for three days to observe the changes in follicular development. Read More

View Article and Full-Text PDF
September 2021

MIDGET:Detecting differential gene expression on microarray data.

Comput Methods Programs Biomed 2021 Sep 16;211:106418. Epub 2021 Sep 16.

Department of Automatic Control and Industrial Informatics, Faculty of Automatic Control and Computer Science, University "Politehnica" of Bucharest, Splaiul Independentei nr. 313, Sector 6, Bucuresti, 060042, Romania. Electronic address:

Backgound and Objective: Detecting differentially expressed genes is an important step in genome wide analysis and expression profiling. There are a wide array of algorithms used in today's research based on statistical approaches. Even though the current algorithms work, they sometimes miss-predict. Read More

View Article and Full-Text PDF
September 2021

Lightweight deep neural networks for cholelithiasis and cholecystitis detection by point-of-care ultrasound.

Comput Methods Programs Biomed 2021 Aug 30;211:106382. Epub 2021 Aug 30.

Graduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan; Clinical Big Data Research Center, Taipei Medical University Hospital, Taipei 110, Taiwan. Electronic address:

Background And Objective: Emergency physicians (EPs) frequently deal with abdominal pain, including that is caused by either gallstones or acute cholecystitis. Easy access and low cost justify point-of-care ultrasound (POCUS) use as a first-line test to detect these diseases; yet, the detection performance of POCUS by EPs is unreliable, causing misdiagnoses with serious impacts. This study aimed to develop a machine learning system to detect and localize gallstones and to detect acute cholecystitis by ultrasound (US) still images taken by physicians or technicians for preliminary diagnoses. Read More

View Article and Full-Text PDF

Using machine learning methods to predict hepatic encephalopathy in cirrhotic patients with unbalanced data.

Comput Methods Programs Biomed 2021 Sep 16;211:106420. Epub 2021 Sep 16.

Department of Health Statistics, Shanxi Medical University, Taiyuan, China. Electronic address:

Objective: Hepatic encephalopathy (HE) is among the most common complications of cirrhosis. Data for cirrhosis with HE is typically unbalanced. Traditional statistical methods and machine learning algorithms thus cannot identify a few classes. Read More

View Article and Full-Text PDF
September 2021

Human cytomegalovirus non-primary infection during pregnancy: antibody response, risk factors and newborn outcome.

Clin Microbiol Infect 2021 Sep 20. Epub 2021 Sep 20.

Genetics, Transplantology and Cardiovascular Diseases Laboratories, IRCCS Policlinico San Matteo Foundation, Pavia, Italy; Molecular Virology Unit, Department of Microbiology and Virology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.

Objectives: Human cytomegalovirus (HCMV) non-primary infections can occur in pregnant women and may result in congenital infection. Comprehensive studies investigating the frequency, characteristics, risk factors and immune response of non-primary infection in pregnancy are missing, while rate of vertical transmission is not known.

Methods: HCMV non-primary infection was investigated prospectively in 250 pregnant women. Read More

View Article and Full-Text PDF
September 2021

Impact of bronchial wall thickness on airflow obstruction in bronchiectasis.

Respir Physiol Neurobiol 2021 Sep 20:103788. Epub 2021 Sep 20.

Department of Respiratory Medicine, National Hospital Organization Osaka Toneyama Medical Center, Toyonaka, Japan.

The association between airflow obstruction and bronchial dilation has been researched in bronchiectasis. However, the impact of bronchial wall thickening on airflow obstruction has not been thoroughly investigated. This study assessed the underlying mechanism of airflow obstruction in bronchiectasis due to abnormal bronchial wall thickening using oscillometry. Read More

View Article and Full-Text PDF
September 2021

A novel echocardiographic parameter to identify individuals susceptible to acute mountain sickness.

Travel Med Infect Dis 2021 Sep 20:102166. Epub 2021 Sep 20.

Institute of Cardiovascular Disease of PLA, The Second Affiliated Hospital, Third Military Medical University (Army Medical University), Chongqing, 400037, China; Department of Cardiology, The Second Affiliated Hospital, Third Military Medical University (Army Medical University), Chongqing, 400037, China. Electronic address:

Background: Acute mountain sickness (AMS) may cause life-threatening conditions. This study aimed to screen echocardiographic parameters at sea level (SL) to identify predictors of AMS development.

Methods: Overall, 106 healthy men were recruited at SL and ascended to 4100 m within 7 days by bus. Read More

View Article and Full-Text PDF
September 2021

Genetic characteristics of human papillomavirus type 16, 18, 52 and 58 in southern China.

Genomics 2021 Sep 20. Epub 2021 Sep 20.

BGI-Shenzhen, Shenzhen 518083, China; Shenzhen Key Laboratory of Unknown Pathogen Identification, BGI-Shenzhen, Shenzhen 518083, China; School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China. Electronic address:

Persistent infections of high-risk human papillomaviruses (HPVs) are the leading cause of cervical cancers. We collected cervical exfoliated cell samples from females in Changsha city, Hunan Province and obtained 358 viral genomes of four major HPV types, including HPV 16 (n = 82), 18 (n = 35), 52 (n = 121) and 58 (n = 100). The lineage/sublineage distribution of the four HPVs confirmed previous epidemiological reports, with the predominant prevailing sublineage as A4 (50%), A1 (37%) and A3 (13%) for HPV16, A1 (83%) for HPV18, B2 (86%) for HPV52 and A1 (65%), A3 (19%) and A2 (12%) for HPV58. Read More

View Article and Full-Text PDF
September 2021

Effectiveness of one-visit and two-visit endodontic retreatment of teeth with persistent/secondary endodontic infection: a randomized clinical trial with 18-months of follow-up.

J Endod 2021 Sep 20. Epub 2021 Sep 20.

Full Professor - Department of Operative Dentistry, Endodontics Division, Institute of Science and Technology, São Paulo State University (UNESP), Sao Jose dos Campos, Brazil. Electronic address:

Introduction: This randomized clinical trial aimed to compare the effectiveness of endodontic retreatment of teeth with post-treatment apical periodontitis (PTAP) performed in one-visit versus two visits on the reduction of cultivable bacteria (CFUs), lipopolysaccharides (LPS), lipoteichoic acid (LTA), and the periapical lesion volume (mm) after 18-months of follow-up.

Methods: Forty patients diagnosed with PTAP were selected and randomly divided into 2 groups: 1-visit retreatment, and 2-visit retreatment with the placement of Ca(OH) medication for 14 days. Cone-beam computed tomography (CBCT) scans were performed at two stages: preoperatively and after 18-months of follow-up. Read More

View Article and Full-Text PDF
September 2021

Occurrence and air-water diffusive exchange legacy persistent organic pollutants in an oligotrophic north Patagonian lake.

Environ Res 2021 Sep 20:112042. Epub 2021 Sep 20.

GEMA, Center for Genomics, Ecology & Environment, Universidad Mayor, Camino La Pirámide, 5750, Huechuraba, Santiago, Chile. Electronic address:

In this study, the occurrence and diffusive air-water exchange of POPs in Panguipulli Lake (39º42'S-72º13'W), an oligotrophic lake located in northern Patagonia (Chile), were determined. Air and water samples were collected between March and August 2017 (autumn-winter) and analyzed for concentrations of OCPs (α-HCH, β-HCH, γ-HCH and HCB) and PCBs (PCB-28,-52,-101,-118,-153,-158,-180) using gas chromatography coupled with an electron capture detector. The direction of air-water exchange direction was evaluated using a fugacity approach (ƒ ƒ), and net diffusive exchange fluxes (F, ng m d) were also estimated. Read More

View Article and Full-Text PDF
September 2021

Effect of sex and gonadectomy on brain MPTP toxicity and response to dutasteride treatment in mice.

Neuropharmacology 2021 Sep 20:108784. Epub 2021 Sep 20.

Centre de Recherche du CHU de Québec, Axe Neurosciences, 2705, Boulevard Laurier, Québec, (Québec), G1V4G2, Canada; Faculté de Pharmacie, Pavillon Ferdinand-Vandry, 1050, avenue de la Médecine, Université Laval, Québec, (Québec) G1V 0A6, Canada. Electronic address:

The maisn neuropathological feature of Parkinson's disease (PD) is degeneration of dopamine neurons (DA) in the substantia nigra (SN); PD prevalence is higher in men, suggesting a role of sex hormones in neuroprotection. This study sought the effects of sex hormones in the brain in a mouse model of PD and modulation of steroid metabolism/synthesis with the 5α-reductase inhibitor dutasteride shown to protect MPTP male mice. Male and female mice were gonadectomized (GDX) or SHAM operated. Read More

View Article and Full-Text PDF
September 2021

Chasing targets in a pandemic: The impact of COVID-19 on HIV outreach workers for MSM (men who have sex with men) in Jakarta, Indonesia.

Glob Public Health 2021 Sep 23:1-15. Epub 2021 Sep 23.

University Centre of Excellence - ARC Health Policy and Social Innovation, Atma Jaya Catholic University of Indonesia (UCoE - ARC HPSI AJCUI), Jakarta, Indonesia.

The COVID-19 pandemic has had a significant impact on HIV services globally, including community-based outreach programmes. This article draws on a qualitative study of HIV outreach workers for men who have sex with men (MSM) in Jakarta, Indonesia undertaken between July and September 2020. The research documented the impact of the COVID-19 pandemic on HIV outreach programmes for MSM based on interviews, focus group discussions and video diaries collected from outreach workers. Read More

View Article and Full-Text PDF
September 2021

Comparison of healthy blood donor Greyhounds and non-Greyhounds using a novel point-of-care viscoelastic coagulometer.

J Vet Emerg Crit Care (San Antonio) 2021 Sep 23. Epub 2021 Sep 23.

Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, California, USA.

Objective: To measure and compare viscoelastic coagulation in 2 canine blood donor populations using a novel, point-of-care device (VCM Vet Analyzer, VCM).

Design: Cohort study.

Setting: Academic and commercial veterinary blood banks. Read More

View Article and Full-Text PDF
September 2021

Using metatranscriptomics to estimate the diversity and composition of zooplankton communities.

Mol Ecol Resour 2021 Sep 23. Epub 2021 Sep 23.

Biodiversity Research Center, Academia Sinica, Nankang District, Taipei, 11529, Taiwan.

DNA metabarcoding is a rapid, high-resolution tool used for biomonitoring complex zooplankton communities. However, diversity estimates derived with this approach can be biased by the co-detection of sequences from environmental DNA (eDNA), nuclear-encoded mitochondrial (NUMT) pseudogene contamination, and taxon-specific PCR primer affinity differences. To avoid these methodological uncertainties, we tested the use of metatranscriptomics as an alternative approach for characterizing zooplankton communities. Read More

View Article and Full-Text PDF
September 2021

Angiotensin converting enzyme inhibitors stimulate cerebral arteriogenesis.

Acta Physiol (Oxf) 2021 Sep 23:e13732. Epub 2021 Sep 23.

Brandenburg Medical School Theodor Fontane (MHB), Campus University Clinic Brandenburg, Deutsche Angiologie Zentrum Brandenburg-Berlin (DAZB), Department for Angiology, Center for Internal Medicine I, Brandenburg an der Havel, Germany.

Aim: Arteriogenesis constitutes the most efficient endogenous rescue mechanism in cases of cerebral ischemia. The aim of this work was to investigate whether angiotensin converting enzyme inhibitors (ACEi) stimulates, and angiotensin II receptor type 1 blockers (ARB) inhibits cerebral collateral growth by applying a three-vessel occlusion (3-VO) model in rat.

Methods: Cerebral collateral growth was measured post 3-VO (1) by assessing blood flow using the cerebrovascular reserve capacity (CVRC) technique, and (2) by assessing vessel diameters in the posterior cerebral artery (PCA) via the evaluation of latex angiographies. Read More

View Article and Full-Text PDF
September 2021

Sub-maximal aerobic exercise training reduces hematocrit and ameliorates symptoms in Andean highlanders with Chronic Mountain Sickness.

Exp Physiol 2021 Sep 23. Epub 2021 Sep 23.

Laboratorio de Fisiología Comparada, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Perú.

New Findings: What is the central question of this study? What is the effect of sub-maximal aerobic exercise training on signs and symptoms of chronic mountain sickness (CMS) in Andean highlanders? What is the main finding and its importance? Aerobic exercise training effectively reduces hematocrit, ameliorates symptoms, and improves aerobic capacity in CMS patients, suggesting that a regular aerobic exercise training program might be used as a low-cost non-invasive/non-pharmacological management strategy of this syndrome.

Abstract: Excessive erythrocytosis (EE) is the hallmark sign of Chronic Mountain Sickness (CMS), a debilitating syndrome associated with neurological symptoms and increased cardiovascular risk. We have shown that unlike sedentary residents at the same altitude, trained individuals maintain hematocrit within sea-level range, and thus we hypothesize that aerobic exercise training (ET) might reduce excessive hematocrit and ameliorate CMS signs and symptoms. Read More

View Article and Full-Text PDF
September 2021