20,802 results match your criteria coinfection

Non-adherence to LDV/SOF did not predict SVR in a randomized controlled trial of HIV/HCV coinfected persons who use drugs.

J Infect Dis 2021 Sep 20. Epub 2021 Sep 20.

Department of Medicine, Johns Hopkins School of Medicine, Baltimore MD, USA.

Background: Eliminating Hepatitis C Virus (HCV) will require effective treatment delivery to persons with substance use disorders (SUDs). We evaluated the relationship between ledipasvir/sofosbuvir treatment persistence (receiving 84 tablets), adherence, and sustained virologic response (SVR) in persons with HIV/HCV coinfection.

Methods: Of the 144 participants with HIV/HCV and SUDs, 110 initiated a 12-week treatment course under one of three conditions (usual care, peer mentors, and cash incentives). Read More

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September 2021

Reinfection following successful direct-acting antiviral therapy for HCV infection among people attending an inner-city community health centre in Victoria, Canada.

Int J Drug Policy 2021 Sep 16:103418. Epub 2021 Sep 16.

Cool Aid Community Health Centre, Victoria, Canada.

Background: Studies of HCV reinfection following direct-acting antiviral (DAA) therapy among PWID have been limited by short follow-up and small case numbers. This study evaluated the incidence of HCV reinfection following successful DAA therapy among people attending an inner-city community health centre in Victoria, Canada.

Methods: In this observational study, participants treated with DAA therapy between November 2014 and December 31, 2019 were included. Read More

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September 2021

Human Immunodeficiency Virus Infection Promotes Human Papillomavirus-Mediated Anal Squamous Carcinogenesis: An Immunologic and Pathobiologic Review.

Pathobiology 2021 Sep 14:1-12. Epub 2021 Sep 14.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Background: Anal squamous cell carcinoma (SCC) is a rare gastrointestinal malignancy with rising incidence, both in the United States and internationally. The primary risk factor for anal SCC is human papillomavirus (HPV) infection. However, there is a growing burden of disease in patients with human immunodeficiency virus (HIV) and HPV coinfection, with the incidence of anal SCC significantly increasing in this population. Read More

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September 2021

Impact of coinfection status and comorbidity on disease severity in adult emergency department patients with influenza B.

Influenza Other Respir Viruses 2021 Sep 17. Epub 2021 Sep 17.

Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Background: Influenza B accounts for approximately one fourth of the seasonal influenza burden. However, research on the importance of influenza B has received less attention compared to influenza A. We sought to describe the association of both coinfections and comorbidities with disease severity among adults presenting to emergency departments (ED) with influenza B. Read More

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September 2021

Epidemiological risk factors associated with primary infection by Epstein-Barr virus in HIV-1-positive subjects in the Brazilian Amazon region.

Sci Rep 2021 Sep 16;11(1):18476. Epub 2021 Sep 16.

Laboratory of Virology, Institute of Biological Sciences, Federal University of Pará, Belém, Pará, Brazil.

To identify the prevalence and risk factors for primary Epstein-Barr virus (EBV) infection in human immunodeficiency virus (HIV)-1-positive adult treatment-naïve patients between January 2018 and December 2019 in a state of the Brazilian Amazon region. A total of 268 HIV-1 positive patients and 65 blood donors participated in the study. Epidemiological data were obtained from medical records and through a designed questionnaire. Read More

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September 2021

Acute retinal necrosis caused by co-infection with multiple viruses in a natalizumab-treated patient: a case report and brief review of literature.

BMC Ophthalmol 2021 Sep 16;21(1):337. Epub 2021 Sep 16.

Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Acute retinal necrosis is considered a rare infectious uveitis. This condition is usually caused by varicella-zoster virus or herpes simplex virus. Acute retinal necrosis caused by co-infection with multiple viruses is extremely rare. Read More

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September 2021

TB in paediatric kidney transplant recipients - A single-centre experience.

Pediatr Transplant 2021 Sep 16:e14141. Epub 2021 Sep 16.

Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa.

Background: TB remains a major challenge in transplantation, particularly in endemic countries. This study aimed to describe the incidence, clinical presentation and outcomes of TB in paediatric kidney transplant recipients and to assess the impact of INH prophylaxis.

Methods: Single-centre retrospective descriptive analysis of children who received kidney transplants from 1995 to 2019 was carried out. Read More

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September 2021

Identification of boosepivirus B in U.S. calves.

Arch Virol 2021 Sep 15. Epub 2021 Sep 15.

Animal Disease Research and Diagnostic Laboratory, Department of Veterinary and Biomedical Sciences, South Dakota State University, Brookings, SD, 57007, USA.

Bovine enteric disease has a complex etiology that can include viral, bacterial, and parasitic pathogens and is a significant source of losses due to morbidity and mortality. Boosepivirus was identified in calves with enteric disease with unclear etiology in Japan in 2009 and has not been reported elsewhere. Metagenomic sequencing and PCR here identified boosepivirus in bovine enteric disease diagnostic submissions from six states in the USA with 98% sequence identity to members of the species Boosepivirus B. Read More

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September 2021

Survival Status and Predictors of Mortality among Multidrug-Resistant Tuberculosis Patients in Saint Peter's Specialized Hospital, Addis Ababa, Ethiopia.

Can J Infect Dis Med Microbiol 2021 3;2021:6696199. Epub 2021 Sep 3.

Department of Nutrition and Reproductive Health, School of Public Health, Mizan-Tepi University, Tepi, Ethiopia.

Background: Multidrug-Resistant Tuberculosis (MDR-TB) is tuberculosis that is resistant to at least both rifampicin and isoniazid. The World Health Organization as reported in 2019 revealed that Ethiopia is among the 20 countries with the highest estimated numbers of incident MDR-TB cases. However, supporting evidence is limited in the study area after the Ethiopian national strategic plan for tuberculosis prevention and control is started. Read More

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September 2021

Disseminated Coinfection by and in a Non-HIV Case.

Infect Drug Resist 2021 7;14:3619-3625. Epub 2021 Sep 7.

Department of Respiratory and Critical Care Medicine, Guangxi Medical University Wuming Affiliated Hospital, Nanning, Guangxi, 530199, People's Republic of China.

Background: is a rapidly growing non-tuberculous mycobacterium (NTM) with weak pathogenicity. Here, we present a rare case of disseminated and coinfection in a human immunodeficiency virus (HIV) negative patient.

Case Presentation: A 28-year-old female was admitted to our hospital due to 2 months of swelling of lymph nodes on the right side of her cervix, accompanied by repeated low fever for more than 1 month. Read More

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September 2021

Influenza in patients with respiratory failure admitted to intensive care units in Poland and the use of extracorporeal respiratory support: a survey-based multicenter study.

BMC Infect Dis 2021 Sep 15;21(1):954. Epub 2021 Sep 15.

Department of Anaesthesiology and Intensive Therapy, Wroclaw Medical University, Borowska 213, 50-556, Wrocław, Poland.

Background: In Poland, little is known about the most serious cases of influenza that need admittance to the intensive care unit (ICU), as well as the use of extracorporeal respiratory support.

Methods: This was an electronic survey comprising ICUs in two administrative regions of Poland. The aim of the study was to determine the number of influenza patients with respiratory failure admitted to the ICU in the autumn-winter season of 2018/2019. Read More

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September 2021

Symbiotic and antagonistic disease dynamics on networks using bond percolation.

Phys Rev E 2021 Aug;104(2-1):024303

School of Computer Science, University of St Andrews, St Andrews, Fife KY16 9SX, United Kingdom; School of Chemistry, University of St Andrews, St Andrews, Fife KY16 9ST, United Kingdom; and School of Biology, University of St Andrews, St Andrews, Fife KY16 9TH, United Kingdom.

In this paper we introduce a description of the equilibrium state of a bond percolation process on random graphs using the exact method of generating functions. This allows us to find the expected size of the giant connected component (GCC) of two sequential bond percolation processes in which the bond occupancy probability of the second process is modulated (increased or decreased) by a node being inside or outside of the GCC created by the first process. In the context of epidemic spreading this amounts to both an antagonistic partial immunity and a synergistic partial coinfection interaction between the two sequential diseases. Read More

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Olfactory entry promotes herpesvirus recombination.

J Virol 2021 Sep 15:JVI0155521. Epub 2021 Sep 15.

School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australia.

Herpesvirus genomes show abundant evidence of past recombination. Its functional importance is unknown. A key question is whether recombinant viruses can outpace the immunity induced by their parents to reach higher loads. Read More

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September 2021

Pulmonary and Co-Infection: A report of two cases.

Sultan Qaboos Univ Med J 2021 Aug 29;21(3):495-498. Epub 2021 Aug 29.

Jawaharlal Institute of Postgraduate Medical Education & Research.

Co-infections or consecutive infections of mucormycosis and aspergillosis are very rare. Additionally, distinguishing between these two infections is also difficult as both these conditions have similar clinical features. We report two similar cases from Tamilnadu, who presented to a tertiary care centre in Puducherry, India in 2017 (first case) and 2019 (second case). Read More

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[Long-term therapeutic effects and liver fibrosis changes with direct-antiviral therapy in HIV/HCV co-infected patients].

Zhonghua Gan Zang Bing Za Zhi 2021 Aug;29(8):776-780

Infectious Disease Center, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou 510060, China.

To investigate the long-term characteristic changes of virus, immune status, and liver fibrosis markers in human immunodeficiency virus (HIV)/hepatitis C virus (HCV) co-infected patients after receiving direct-antiviral agents (DAAs). HIV/HCV co-infected patients who visited the Guangzhou Eighth People's Hospital, Guangzhou Medical University from May 2014 to December 2019 were selected as the research subjects. The changes of virological response rate, peripheral blood CD4(+)T lymphocyte level and serological markers of liver fibrosis (APRI score and FIB-4 index) were observed during 144 weeks of follow-up course after the end of DAAs treatment. Read More

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HIV and COVID-19: review of clinical course and outcomes.

HIV Res Clin Pract 2021 Sep 12:1-17. Epub 2021 Sep 12.

University of Colorado, Department of Medicine, Division of Infectious Diseases, University of Colorado, Aurora, CO, USA.

Understanding the relationship between HIV and SARS-CoV-2 has important public health implications.To summarize current research on COVID-19 among people with HIV (PWH) as published through 15 July 2021. We conducted a search of PubMed, Scopus, preprint databases (medRxiv, bioRxiv), and the references of publications found using key terms relevant to COVID-19 ('COVID-19' OR 'SARS-CoV-2' OR 'coronavirus') AND to HIV ('HIV' OR 'Human Immunodeficiency Virus' OR 'AIDS' OR 'Acquired Immunodeficiency Syndrome'). Read More

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September 2021

Delta variant and black fungal invasion: A bidirectional assault might worsen the massive second/third stream of COVID-19 outbreak in South-Asia.

Ethics Med Public Health 2021 Dec 4;19:100722. Epub 2021 Sep 4.

Department of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh.

Background: Here, we have shortly reported the recent updates on the disastrous progressions of the deadly delta variant and a virulent coinfection or post-COVID-19 infection of black fungus in India and its neighbouring countries.

Methodology: We searched by utilizing appropriate keywords in Google Scholar, PubMed and other scholarly databases alongside several national and international newspapers to collect the latest data regarding the targeted topic.

Results: Recently, the delta variant is wreaking havoc in India, UK, and other countries around the globe and has also exhibited successful infections in around 20 to 55% of the people who have already recovered from COVID-19 originating from the different strains. Read More

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December 2021

Advanced Research in Porcine Reproductive and Respiratory Syndrome Virus Co-infection With Other Pathogens in Swine.

Front Vet Sci 2021 26;8:699561. Epub 2021 Aug 26.

State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, China.

The porcine reproductive and respiratory syndrome virus (PRRSV) is the pathogen causing epidemics of porcine reproductive and respiratory syndrome (PRRS), and is present in every major swine-farming country in the world. Previous studies have demonstrated that PRRSV infection leads to a range of consequences, such as persistent infection, secondary infection, and co-infection, and is common among pigs in the field. In recent years, coinfection of PRRSV and other porcine pathogens has occurred often, making it more difficult to define and diagnose PRRSV-related diseases. Read More

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Major Insights in Dynamics of Host Response to SARS-CoV-2: Impacts and Challenges.

Front Microbiol 2021 25;12:637554. Epub 2021 Aug 25.

Department of Genetic Engineering and Biotechnology, School of Life Sciences, Shahjalal University of Science and Technology, Sylhet, Bangladesh.

The coronavirus disease 2019 (COVID-19), a pandemic declared by the World Health Organization on March 11, 2020, is caused by the infection of highly transmissible species of a novel coronavirus called severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). As of July 25, 2021, there are 194,372,584 cases and 4,167,937 deaths with high variability in clinical manifestations, disease burden, and post-disease complications among different people around the globe. Overall, COVID-19 is manifested as mild to moderate in almost 90% of the cases and only the rest 10% of the cases need hospitalization. Read More

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Rhinocerebral Mucormycosis in a COVID-19 Patient from Nepal: A Case Report.

JNMA J Nepal Med Assoc 2021 Jul 30;59(239):703-705. Epub 2021 Jul 30.

Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.

With the surge of cases during the second wave of COVID-19 in Nepal, a number of mucormycosis coinfection cases have also come to our attention. We present a case of a 65-year-old female who was admitted to our emergency department with complaints of pain, swelling, and tingling sensation of the left side of the face along with blood-tinged nasal discharge for 20 days. She had been tested positive for COVID-19 a month back and managed with oxygen support and corticosteroids. Read More

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Coinfection with dengue and hepatitis A complicated with infective endocarditis in a Yemeni patient: a case report.

J Med Case Rep 2021 Sep 11;15(1):450. Epub 2021 Sep 11.

University of Science and Technology Hospital, Sana'a, Yemen.

Introduction: Coinfection with dengue and hepatitis A is rare and challenging for physicians since their clinical features can be overlapping. These infections are self-limiting but can become complicated by subsequent infective endocarditis. We report a case of infective endocarditis following a coinfection with dengue and hepatitis A. Read More

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September 2021

Ocurrence of rotavirus and picobirnavirus in wild and exotic avian from amazon forest.

PLoS Negl Trop Dis 2021 Sep 10;15(9):e0008792. Epub 2021 Sep 10.

Evandro Chagas Institute, Ministry of Health, Ananindeua, Pará, Brazil.

The present study reports the occurrence of rotavirus A (RVA), rotavirus D (RVD), rotavirus F (RVF), rotavirus G (RVG), and picobirnavirus (PBV) in fecal specimens of wild (n = 22), and exotic birds (n = 1) from different cities of Pará state. These animals were hospitalized at Veterinary Hospital of the Federal University of Pará, Brazil, in a period from January 2018 to June 2019. The animals exhibited different clinical signs, such as diarrhea, malnutrition, dehydration, and fractures. Read More

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September 2021

COVID-19 and Tuberculosis Coinfection: An Overview of Case Reports/Case Series and Meta-Analysis.

Front Med (Lausanne) 2021 24;8:657006. Epub 2021 Aug 24.

Department of Respiratory and Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.

Coronavirus disease 2019 (COVID-19) and tuberculosis (TB) are two major infectious diseases posing significant public health threats, and their coinfection (aptly abbreviated COVID-TB) makes the situation worse. This study aimed to investigate the clinical features and prognosis of COVID-TB cases. The PubMed, Embase, Cochrane, CNKI, and Wanfang databases were searched for relevant studies published through December 18, 2020. Read More

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Hodgkin Lymphoma in People Living with HIV.

Cancers (Basel) 2021 Aug 29;13(17). Epub 2021 Aug 29.

Department of Hematology, Institute Català d'Oncologia-Germans Trias i Pujol Hospital, Carretera de Canyet s/n, 08916 Barcelona, Spain.

Despite widespread use of combined antiretroviral therapy (cART) and increased life expectancy in people living with HIV (PLWH), HIV-related lymphomas (HRL) remain a leading cause of cancer morbidity and mortality for PLWH, even in patients optimally treated with cART. While the incidence of aggressive forms of non-Hodgkin lymphoma decreased after the advent of cART, incidence of Hodgkin lymphoma (HL) has increased among PLWH in recent decades. The coinfection of Epstein-Barr virus plays a crucial role in the pathogenesis of HL in the HIV setting. Read More

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Leptospirosis and Coinfection: Should We Be Concerned?

Int J Environ Res Public Health 2021 Sep 6;18(17). Epub 2021 Sep 6.

Department of Biological Sciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, UKM, Bangi 43600, Selangor, Malaysia.

Pathogenic is the causative agent of leptospirosis, an emerging zoonotic disease affecting animals and humans worldwide. The risk of host infection following interaction with environmental sources depends on the ability of to persist, survive, and infect the new host to continue the transmission chain. may coexist with other pathogens, thus providing a suitable condition for the development of other pathogens, resulting in multi-pathogen infection in humans. Read More

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September 2021

HCV Cure With Direct-Acting Antivirals Improves Liver and Immunological Markers in HIV/HCV-Coinfected Patients.

Front Immunol 2021 23;12:723196. Epub 2021 Aug 23.

Unidad de Infección Viral e Inmunidad, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.

Hepatitis C virus (HCV) cure after all-oral direct-acting antiviral (DAA) therapy greatly improves the liver and immune system. We aimed to assess the impact of this HCV clearance on immune system-related markers in plasma and the gene expression profile in human immunodeficiency virus (HIV)/HCV-coinfected patients with advanced cirrhosis. We performed a prospective study on 33 HIV/HCV-coinfected patients at baseline and 36 weeks after the sustained virological response. Read More

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Deciphering SARS-CoV-2 mortality: H1N1 as an aid.

Rev Assoc Med Bras (1992) 2021 04;67(4):634-636

Institute of Lung Biology and Disease, Comprehensive Pneumology Center, German Research Center for Environmental Health - Munich, Germany.

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Concomitant disseminated tuberculosis and lepromatous leprosy in a previously healthy male.

Int J Mycobacteriol 2021 Jul-Sep;10(3):330-334

Department of General Medicine, Government Medical College and Hospital, Sector 32, Chandigarh, India.

Tuberculosis (TB) and leprosy are two chronic mycobacterial infections caused by intracellular Gram-positive aerobic acid-fast bacilli. Both have highly variable presentations depending on immunological milieu of the host and account for significant disease morbidity. The burden of these age-old infections of humanity still remains high in India. Read More

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September 2021

[Endophthalmitis Caused by Mixed Infections in Silicone Oil-filled Eye:One Case Report].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2021 Aug;43(4):659-662

Department of Ophthalmology,Beijing 100730,China.

The incidence of endophthalmitis after vitrectomy is extremely low,especially lower in silicone oil-filled eyes.Silicone oil exerts a toxic effect on the cell membranes of microorganisms and leads to the lack of nutrients.It is thus believed to inhibit the growth of bacteria and fungi. Read More

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