1,273 results match your criteria coagulation zone


[Screening for retinopathy of prematurity-the most important changes in the new German guidelines 2020].

Ophthalmologe 2021 Apr 30. Epub 2021 Apr 30.

Universität zu Köln, Zentrum für Augenheilkunde, Medizinische Fakultät und Uniklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.

Background: Due to improvements in neonatal care of premature infants and the development of novel treatment options for retinopathy of prematurity (ROP), the requirements for screening for ROP have changed since publication of the last version of the German ROP screening guideline in 2008. Based on results of recent studies, the guideline has been extensively revised in 2020 and published in an updated version.

Objective: This article summarizes the most important changes in the new guideline. Read More

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Short pulsed microwave ablation: computer modeling and experiments.

Int J Hyperthermia 2021 ;38(1):409-420

BioMIT, Department of Applied Mathematics, Universitat Politècnica de València, Valencia, Spain.

Purpose: To study the differences between continuous and short-pulse mode microwave ablation (MWA).

Methods: We built a computational model for MWA including a 200 mm long and 14 G antenna from Amica-Gen and solved an electromagnetic-thermal coupled problem using COMSOL Multiphysics. We compared the coagulation zone (CZ) sizes created with pulsed and continuous modes under and conditions. Read More

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January 2021

Bipolar radiofrequency ablation treatment of liver cancer employing monopolar needles: A comprehensive investigation on the efficacy of time-based switching.

Comput Biol Med 2021 Apr 16;131:104273. Epub 2021 Feb 16.

School of Engineering and Information Technology, Faculty of Science and Technology, Federation University, VIC, 3350, Australia.

Radiofrequency ablation (RFA) is a thermal ablative treatment method that is commonly used to treat liver cancer. However, the thermal coagulation zone generated using the conventional RFA system can only successfully treat tumours up to 3 cm in diameter. Switching bipolar RFA has been proposed as a way to increase the thermal coagulation zone. Read More

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Genome-wide ancestry and introgression in a Zambian baboon hybrid zone.

Mol Ecol 2021 04 16;30(8):1907-1920. Epub 2021 Mar 16.

Department of Anthropology, Washington University, St. Louis, MO, USA.

Hybridization in nature offers unique insights into the process of natural selection in incipient species and their hybrids. In order to evaluate the patterns and targets of selection, we examine a recently discovered baboon hybrid zone in the Kafue River Valley of Zambia, where Kinda baboons (Papio kindae) and grey-footed chacma baboons (P. ursinus griseipes) coexist with hybridization. Read More

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Continuous flow pulsed power plasma reactor for the treatment of aqueous solution containing volatile organic compounds and real pharmaceutical wastewater.

J Environ Manage 2021 May 19;286:112202. Epub 2021 Feb 19.

Department of Civil Engineering, Indian Institute of Technology Madras, 600036, India.

The degradation of four recalcitrant and toxic VOCs (volatile organic compounds) present in pharmaceutical wastewater was studied using a continuous flow plasma reactor, along with evaluating its potential for real effluent treatment. The wastewater was sprayed into the plasma zone of the reactor, and it was re-circulated for better performance. The effect of different HRTs (hydraulic retention time) and initial concentrations of VOCs on the degradation efficiency were evaluated. Read More

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[Possibilities of an experimental damaging effect on the retinal pigment epithelium].

Vestn Oftalmol 2021 ;137(1):5-12

Vavilov Institute of General Genetics, Moscow, Russia.

Purpose: To simulate the damaging effect on retinal pigment epithelium (RPE) in an experiment studying the effect of human neuronal precursors (NPs).

Material And Methods: The study was carried out on 31 rabbits (31 eyes) of the Chinchilla breed, which were divided into 3 groups: the 1 group received a subretinal injection of balanced saline solution (BSS); the 2 group - subretinal injection of BSS with vitrectomy, displacement of the injection bladder away from the injection site using a perfluororganic compound (PFOC) and laser coagulation; the 3 group - subretinal injection of a culture of NPs using the same method as in the group 2. All rabbits were observed for 21 days using ophthalmoscopy, optical coherence tomography (OCT) and autofluorescence (AF). Read More

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February 2021

Avascular island in the vascularised retina in zone II ROP.

BMJ Case Rep 2021 Jan 28;14(1). Epub 2021 Jan 28.

Neonatology, Government Medical College and Hospital, Chandigarh, India.

We describe an atypical form of avascular island demarcated by a ridge in the vascularised retina of retinopathy of prematurity. Fundus fluorescein angiography showed an unusual finding of an avascular island demarcated by shunt vessels in vascularised retina posterior to the ridge. There is a need to document this finding as this could throw some light on the aetiopathogenesis of the disease. Read More

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January 2021

Fast calculation of 3D radiofrequency ablation zone based on a closed-form solution of heat conduction equation fitted by ex vivo measurements.

Phys Med Biol 2021 Feb 25;66(5):055022. Epub 2021 Feb 25.

School of Mathematical Sciences, Qufu Normal University, Qufu 273165, People's Republic of China.

Fast calculation or simulation of the ablation zone induced by radiofrequency ablation (RFA) has a critical role in hepatic RFA planning and therapy. However, it remains challenging to approximate the ablation zone in real time, especially when more than one probe is involved in one ablation session. This paper presents a novel computational technique to calculate the 3D ablation zone of one probe RFA and two-probe switching RFA. Read More

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February 2021

Comparison of thermal injury depth of the prostate between plasma kinetic electrode, holmium laser, green light laser and Nd:YAG laser.

Int Urol Nephrol 2021 May 22;53(5):863-867. Epub 2021 Jan 22.

Department of Urology, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.

Objective: PlasmaKinetic electrode, holmium laser, green laser and Nd: YAG laser have been used for treating benign prostate hyperplasia (BPH). To compare the pathological changes of thermal injury by these different devices.

Material And Methods: Tissues donated by several male patients with prostate cancer who have written a consent. Read More

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Percutaneous ultrasound guided PEG-coated gold nanoparticles enhanced radiofrequency ablation in liver.

Sci Rep 2021 Jan 14;11(1):1316. Epub 2021 Jan 14.

3rd Medical Department, "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Cluj-Napoca, Romania.

To investigate the effects of PEG-coated gold nanoparticles on ablation zone volumes following in vivo radiofrequency ablation of porcine liver. This prospective study was performed following institutional animal care and committee approval was used. Radiofrequency ablations were performed in the livers of ten Sus scrofa domesticus swines. Read More

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January 2021

The perifollicular zone of the spleen as a distributor and filter of blood components.

Authors:
Shunichi Sasou

J Clin Exp Hematop 2021 Mar 8;61(1):58-60. Epub 2021 Jan 8.

Department of Pathology, Hachinohe Red Cross Hospital, Hachinohe, Japan.

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Sickle Cell Maculopathy: Microstructural Analysis Using OCTA and Identification of Genetic, Systemic, and Biological Risk Factors.

Am J Ophthalmol 2021 04 4;224:7-17. Epub 2021 Jan 4.

Service d'ophtalmologie, CHU de Pointe-à-Pitre/Abymes, Pointe-à-Pitre, Guadeloupe, France; Université de Paris, UMR_S1134, BIGR, INSERM, Paris, France; Université des Antilles, UMR_S1134, BIGR, Pointe-à-Pitre, Guadeloupe, France; Université des Antilles, Guadeloupe (FWI), France.

Purpose: To identify genetic, systemic, and biological factors associated with the occurrence of sickle cell maculopathy (SCM). To evaluate microvascular macular alterations using optical coherence tomography angiography (OCTA) in sickle cell disease (SCD).

Design: Cross-sectional study. Read More

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Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA): update and insights into current practices and future directions for research and implementation.

Scand J Trauma Resusc Emerg Med 2021 Jan 6;29(1). Epub 2021 Jan 6.

Extracorporeal Life Support Capability Area, United States Army Institute of Surgical Research, JBSA Ft. Sam Houston, San Antonio, TX, 78234, USA.

Background: In this review, we assess the state of Resuscitative Endovascular Occlusion of the Aorta (REBOA) today with respect to out-of-hospital (OOH) vs. inhospital (H) use in blunt and penetrating trauma, as well as discuss areas of promising research that may be key in further advancement of REBOA applications.

Methods: To analyze the trends in REBOA use, we conducted a review of the literature and identified articles with human or animal data that fit the respective inclusion and exclusion criteria. Read More

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January 2021

Radiofrequency ablation combined with conductive fluid-based dopants (saline normal and colloidal gold): computer modeling and ex vivo experiments.

Biomed Eng Online 2021 Jan 6;20(1). Epub 2021 Jan 6.

Facultad de Ingeniería, Universidad Autónoma de San Luis Potosí, San Luis Potosí, SLP 78290, México.

Background: The volume of the coagulation zones created during radiofrequency ablation (RFA) is limited by the appearance of roll-off. Doping the tissue with conductive fluids, e.g. Read More

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January 2021

The effects of sildenafil and N-acetylcysteine the zone of stasis in burns.

Ulus Travma Acil Cerrahi Derg 2021 01;27(1):9-16

Department of General Surgery, Sivas Cumhuriyet University Faculty of Medicine, Sivas-Turkey.

Background: In burn wound healing, zones of burn, namely zone of hyperemia, the zone of stasis, and zone of coagulation, have crucial importance. These zones have been identified based on the pathophysiology of the burn, and treatment of burn has been improved. The zone of necrosis is treated by excision and repair through grafting. Read More

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January 2021

Two-compartment mathematical modeling in RF tumor ablation: New insight when irreversible changes in electrical conductivity are considered.

Math Biosci Eng 2020 11;17(6):7980-7993

Facultad de Ingeniería, Universidad Autónoma de San Luis Potosí, San Luis Potosí, SLP 78290, México.

The objective was to explore variations of temperature distribution and coagulation zone size computed by a two-compartment radiofrequency ablation (RFA) model when including simultaneously reversible changes in the tissue electrical conductivity (σ) due to temperature and irreversible changes due to thermal coagulation. Two-compartment (tumor and healthy tissue) models were built and simulated. Reversible change of σ was modeled by a piecewise function characterized by increments of +1. Read More

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November 2020

Prevalence of Coagulation Factors Deficiency among Young Adults in Saudi Arabia: A National Survey.

TH Open 2020 Oct 23;4(4):e457-e462. Epub 2020 Dec 23.

Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Alfaisal University, Riyadh, Saudi Arabia.

 Inherited bleeding disorders vary in prevalence due to genetic disparity and ethnicity. Little is known about the prevalence of coagulation factor deficiency and bleeding disorders in middle-eastern population.  Young Saudi adults with at least one positive bleeding symptom reported in semi-structured validated condensed MCMDM-1vWD questionnaire were tested for complete blood count, routine and special coagulation tests, serum ferritin level, and capillary zone electrophoresis. Read More

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October 2020

Chitosan Woven Meshes: Influence of Threads Configuration on Mechanical, Morphological, and Physiological Properties.

Polymers (Basel) 2020 Dec 25;13(1). Epub 2020 Dec 25.

Department of Materials Engineering, Federal University of Campina Grande, Campina Grande, PB 58429-900, Brazil.

This study aimed to develop meshes from the weaving of mono- and multifilament wet-spun chitosan (CS), for possible biomedical applications. In the wet-spinning process, CS solution (4% /) was extruded in a coagulation bath containing 70% sodium hydroxide solution (0.5 M), and 30% methanol was used. Read More

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December 2020

The Integration of a Dual-Wavelength Super Pulsed Diode Laser for Consistent Tissue Ablation in the Esthetic Zone: A Case Series.

Case Rep Dent 2020 3;2020:8883156. Epub 2020 Dec 3.

Faculty of Dentistry, Islamic Science University of Malaysia (USIM), Malaysia.

Introduction: A diode laser is one of the universally compact accepted laser systems used fundamentally for soft tissue applications. Most diode laser devices have a single wavelength of either 810 nm for superior coagulation or 980 nm for tissue ablation. In these case series, the use of dual wavelengths (810 nm and 980 nm) in combination with super pulsing has provided a cleaner cut (no charring) with faster healing that eases the placement of the final restoration in the esthetic zone. Read More

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December 2020

Chandler-Loop surveyed blood compatibility and dynamic blood triggered degradation behavior of Zn-4Cu alloy and Zn.

Mater Sci Eng C Mater Biol Appl 2021 Feb 8;119:111594. Epub 2020 Oct 8.

Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China. Electronic address:

Zinc (Zn) and its alloys have been considered promising absorbable metals for medical implants. However, the dynamic interaction between Zn-based materials and human blood after implantation remains unclear. In this study, a modified Chandler-Loop system was applied to assess the blood compatibility and initial degradation behavior of a Zn-4. Read More

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February 2021

OCT-Based Angiography and Surface Topography in Burn-Damaged Skin.

Lasers Surg Med 2020 Dec 11. Epub 2020 Dec 11.

Department of Bioengineering, University of Washington, Seattle, Washington, 98195.

Background And Objectives: There is a clinical need for an accurate, non-invasive imaging tool that can provide the objective assessment of burn wounds. The aims of this study are to demonstrate the potential of optical coherence tomography (OCT) in evaluating burn wound healing, as well as exploring the physiological basis of human wound healing.

Study Design/materials And Methods: This was a retrospective study. Read More

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December 2020

Impact of blood storage duration on hematologic, blood gas, biochemical, and oxidative stress variables in sheep undergoing allogeneic blood transfusions.

Vet Clin Pathol 2020 Dec 5;49(4):545-556. Epub 2020 Dec 5.

School of Veterinary Medicine and Animal Science, University of São Paulo, Cidade Universitária, São Paulo, Brazil.

Background: Hemotherapy in ruminants is limited to whole blood transfusions, sometimes with stored blood for up to 42 days, but little attention has been given to the effect of blood storage times and recipient responses after transfusions.

Objectives: We aimed to evaluate the hematologic and serum biochemical effects after allogeneic blood transfusion with either fresh or stored blood in sheep. We also sought to examine hematologic and biochemical analyte changes in the store blood. Read More

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December 2020

Severe COVID-19: A multifaceted viral vasculopathy syndrome.

Ann Diagn Pathol 2021 Feb 13;50:151645. Epub 2020 Oct 13.

Discovery Life Sciences, Powell, OH, USA; Ohio State University Comprehensive Cancer Center and Discovery Life Sciences, Columbus, OH, USA. Electronic address:

The objective of this study was to elucidate the pathophysiology that underlies severe COVID-19 by assessing the histopathology and the in situ detection of infectious SARS-CoV-2 and viral capsid proteins along with the cellular target(s) and host response from twelve autopsies. There were three key findings: 1) high copy infectious virus was limited mostly to the alveolar macrophages and endothelial cells of the septal capillaries; 2) viral spike protein without viral RNA localized to ACE2+ endothelial cells in microvessels that were most abundant in the subcutaneous fat and brain; 3) although both infectious virus and docked viral spike protein was associated with complement activation, only the endocytosed pseudovirions induced a marked up-regulation of the key COVID-19 associated proteins IL6, TNF alpha, IL1 beta, p38, IL8, and caspase 3. Importantly, this microvasculitis was associated with characteristic findings on hematoxylin and eosin examination that included endothelial degeneration and resultant basement membrane zone disruption and reduplication. Read More

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February 2021

Clinical characteristics and outcomes of patients with severe heatstroke complicated with disseminated intravascular coagulation: A case-control study.

Thromb Res 2021 01 11;197:120-123. Epub 2020 Nov 11.

Department of Critical Care Medicine, The Affiliated General Hospital of Southern Theatre Command of PLA, Southern Medical University, Guangzhou 510515, China; Department of Critical Care Medicine, The Affiliated General Hospital of Southern Theatre Command of PLA, Guangzhou 510010, China; Key Laboratory of Hot Zone Trauma Care and Tissue Repair of PLA, General Hospital of Southern Theatre Command of PLA, Guangzhou 510010, China. Electronic address:

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January 2021

Role of saline concentration during saline-infused radiofrequency ablation: Observation of secondary Joule heating along the saline-tissue interface.

Comput Biol Med 2021 01 11;128:104112. Epub 2020 Nov 11.

School of Engineering and Information Technology, Faculty of Science and Technology, Federation University, VIC, 3350, Australia.

Infusion of saline prior to radiofrequency ablation (RFA) is known to enlarge the thermal coagulation zone. The abundance of ions in saline elevate the electrical conductivity of the saline-saturated region. This promotes greater electric current flow inside the tissue, which increases the amount of RF energy deposition and subsequently enlarges the coagulation zone. Read More

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January 2021

Distal organ inflammation and injury after resuscitative endovascular balloon occlusion of the aorta in a porcine model of severe hemorrhagic shock.

PLoS One 2020 17;15(11):e0242450. Epub 2020 Nov 17.

U. S. Army Burn Center, US Army Institute of Surgical Research, Fort Sam Houston, Texas, United States of America.

Background And Objective: Resuscitative Endovascular Balloon Occlusion of Aorta (REBOA) has emerged as a potential life-saving maneuver for the management of non-compressible torso hemorrhage in trauma patients. Complete REBOA (cREBOA) is inherently associated with the burden of ischemia reperfusion injury (IRI) and organ dysfunction. However, the distal organ inflammation and its association with organ injury have been little investigated. Read More

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January 2021

Increased Immunosignals of Collagen IV and Fibronectin Indicate Ischemic Consequences for the Neurovascular Matrix Adhesion Zone in Various Animal Models and Human Stroke Tissue.

Front Physiol 2020 26;11:575598. Epub 2020 Oct 26.

Paul Flechsig Institute for Brain Research, University of Leipzig, Leipzig, Germany.

Ischemic stroke causes cellular alterations in the "neurovascular unit" (NVU) comprising neurons, glia, and the vasculature, and affects the blood-brain barrier (BBB) with adjacent extracellular matrix (ECM). Limited data are available for the zone between the NVU and ECM that has not yet considered for neuroprotective approaches. This study describes ischemia-induced alterations for two main components of the neurovascular matrix adhesion zone (NMZ), i. Read More

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October 2020

Pathogenicity of severe fever with thrombocytopenia syndrome virus in mice regulated in type I interferon signaling: Severe fever with thrombocytopenia and type I interferon.

Lab Anim Res 2020 21;36:38. Epub 2020 Oct 21.

College of Veterinary Medicine, Jeonbuk National University, Iksan, 54596 Republic of Korea.

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging zoonotic disease, which causes high fever, thrombocytopenia, and death in humans and animals in East Asian countries. The pathogenicity of SFTS virus (SFTSV) remains unclear. We intraperitoneally infected three groups of mice: wild-type (WT), mice treated with blocking anti-type I interferon (IFN)-α receptor antibody (IFNAR Ab), and IFNAR knockout (IFNAR) mice, with four doses of SFTSV (KH1, 5 × 10 to 5 × 10 FAID). Read More

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October 2020

Monitoring microwave ablation using ultrasound homodyned K imaging based on the noise-assisted correlation algorithm: An ex vivo study.

Ultrasonics 2021 Feb 17;110:106287. Epub 2020 Oct 17.

Department of Biomedical Engineering, College of Life Science and Bioengineering, Beijing University of Technology, Beijing, China. Electronic address:

In this paper, we proposed ultrasound homodyned K (HK) imaging based on the noise-assisted correlation algorithm (NCA) for monitoring microwave ablation of porcine liver ex vivo. The NCA-based HK (α and k) imaging was compared with NCA-based Nakagami (m) imaging and NCA-based cumulative echo decorrelation (CED) imaging. Backscattered ultrasound radiofrequency signals of porcine liver ex vivo during and after the heating of microwave ablation were collected (n = 15), which were processed for constructing B-mode imaging, NCA-based HK imaging, NCA-based Nakagami imaging, and NCA-based CED imaging. Read More

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February 2021

Lesion outline and thermal field distribution of ablative in vitro experiments in myocardia: comparison of radiofrequency and laser ablation.

BMC Cardiovasc Disord 2020 10 20;20(1):454. Epub 2020 Oct 20.

Department of Medical Ultrasonics, Division of Interventional Ultrasound, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, Guangdong, China.

Objectives: To explore the lesion outline and thermal field distribution of radiofrequency ablation (RFA) and laser ablation (LA) in myocardial ablation in vitro.

Materials And Methods: Twenty-four fresh porcine hearts were ablated with RFA or LA in vitro. The radiofrequency electrode or laser fiber and two parallel thermocouple probes were inserted into the myocardium under ultrasound guidance. Read More

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October 2020