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Microemulsion-based vaginal gel of clotrimazole: formulation, in vitro evaluation, and stability studies.

AAPS PharmSciTech 2009 21;10(2):476-81. Epub 2009 Apr 21.

Department of Pharmaceutical Sciences and Technology, Institute Chemical Technology, Matunga, Mumbai, 400019, India.

The objective of the present investigation was to develop and evaluate microemulsion-based gel for the vaginal delivery of clotrimazole (CMZ). The solubility of CMZ in oils and surfactants was evaluated to identify components of the microemulsion. The ternary diagram was plotted to identify the area of microemulsion existence. Read More

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