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Endovascular aortic repair for abdominal aortic injury complicated with bowel injury due to blunt abdominal trauma: A case report.

Int J Surg Case Rep 2021 Jul 18;85:106216. Epub 2021 Jul 18.

Department of General Surgery, Shonan Kamakura General Hospital, Kanagawa, Japan.

Introduction And Importance: Blunt abdominal aortic injury (BAAI) resulting from blunt abdominal trauma is rare; therefore, there are no standard guidelines for its treatment. Herein, we report the successful treatment of BAAI via endovascular aortic repair (EVAR) performed immediately after emergency laparotomy to repair a bowel injury.

Case Presentation: A 78-year-old man was injured after being caught between a shovel car and the bumper of his own car for approximately 15 s. Read More

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Medicated multi-targeted alginate-based dressings for potential treatment of mixed bacterial-fungal infections in diabetic foot ulcers.

Int J Pharm 2021 Jul 19:120903. Epub 2021 Jul 19.

School of Science, Faculty of Engineering and Science, University of Greenwich, Medway, Central Ave. Chatham Maritime, Kent ME4 4TB, UK. Electronic address:

Recently developed medicated dressings target either bacterial or fungal infection only, which is not effective for the treatment of mixed infections common in diabetic foot ulcers (DFUs). This study aims to develop advanced bioactive alginate-based dressings (films and wafers) to deliver therapeutically relevant doses of ciprofloxacin (CIP) and fluconazole (FLU) to target mixed bacterial and fungal infections in DFUs. The alginate compatibility with the drugs was confirmed by SEM, XRD, FTIR and texture analysis, while the medicated wafers showed better fluid handling properties than the films in the presence of simulated wound fluid. Read More

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Low Rate of Spontaneous Closure in Premature Infants Discharged with a Patent Ductus Arteriosus: A Multicenter Prospective Study.

J Pediatr 2021 Jul 19. Epub 2021 Jul 19.

The MEDNAX Center for Research, Education, Quality and Safety, Sunrise, FL; Greenville Memorial Hospital, SC.

Objectives: To assess the rate of spontaneous closure and the incidence of adverse events in infants discharged home with a patent ductus arteriosus.

Study Design: In a prospective multicenter study, we enrolled 201 premature infants (gestational age 23-32 weeks at birth) discharged home with a persistently patent ductus arteriosus (PDA) and followed their PDA status at 6-month intervals through 18 months of age. The primary study outcome was the rate and timing of spontaneous ductal closure. Read More

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PDL1 triggered by binding eIF3I contributes to the amelioration of diabetes-associated wound healing defects by regulating IRS4.

J Invest Dermatol 2021 Jul 19. Epub 2021 Jul 19.

Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China; Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, 200443, China. Electronic address:

Persistent chronic inflammation and delayed epithelialization lead to stalled healing in diabetic ulcers (DUs). PDL1 shows anti-inflammatory and proliferative activities in healing defects, while its function in DU pathogenesis remains unknown. Lower levels of PDL1 were found in DU tissues, and exogenous PDL1 has therapeutic effects in healing process by accelerating re-epithelialization and attenuating prolonged inflammation, which contributed to the delayed wound closure. Read More

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A Prospective, Randomized Evaluation of the Quality of Wound Closure With Barbed Versus Standard Suture After Total Joint Arthroplasty.

Alexander P Sah

Orthopedics 2021 Jul-Aug;44(4):216-222. Epub 2021 Jul 1.

Complications such as joint infection or delayed wound healing can lead to morbidity and elevated health care costs after total joint arthroplasty. The purpose of this study was to compare the quality of running knotless barbed suture vs standard monofilament suture wound closure with respect to wound drainage and healing complications after total joint arthroplasty. For this study, 1000 joint arthroplasty patients were prospectively randomized to have fascial, soft tissue, and skin closure with knotless barbed suture vs standard suture during the period 2016 to 2018. Read More

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Growing the Psychiatry Workforce Through Expansion or Creation of Residencies and Fellowships: the Results of a Survey by the AADPRT Workforce Task Force.

Acad Psychiatry 2021 Jul 22. Epub 2021 Jul 22.

Rutgers New Jersey Medical School, Newark, NJ, USA.

Objective: The USA needs to produce more psychiatrists to meet projected workforce deficits. The American Association of Directors of Psychiatric Residency Training Directors (AADPRT) sought to examine opportunities for and obstacles to expanding or creating residencies and fellowships.

Methods: In November 2019, the authors conducted a survey of residency and fellowship directors. Read More

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Invited Discussion on: Percutaneous Intradermal Purse-String Closure for Correction of Male Tuberous Nipple-Areola Complex Deformity.

Aesthetic Plast Surg 2021 Jul 22. Epub 2021 Jul 22.

Division of Plastic Surgery, The New York Presbyterian Hospital/Cornell Weill Medical Center, 114 E. 71stSt, Suite 1W, New York, NY, 10021, USA.

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De novo detrusor overactivity and urgency after mid-urethral slings for urodynamic stress incontinence.

Int Urogynecol J 2021 Jul 22. Epub 2021 Jul 22.

Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Keelung Medical Center, Keelung, Taiwan, Republic of China.

Introduction And Hypothesis: The objective was to identify incidence and risk factors of de novo urgency and detrusor overactivity (DO) following mid-urethral slings (MUS) in patients with urodynamic stress incontinence (USI) without urgency.

Methods: A total of 688 women between January 2004 and July 2017 were reviewed retrospectively. De novo urgency was established with a positive response to question 2 on the Urogenital Distress Inventory-6 questionnaire (UDI-6). Read More

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COVID-19 lockdown: Impact on college students' lives.

J Am Coll Health 2021 Jul 22:1-15. Epub 2021 Jul 22.

University of Utah School of Medicine, Salt Lake City, Utah, USA.

In light of COVID-19, leaders issued stay-at-home orders, including closure of higher-education schools. Most students left campus, likely impacting their employment and social network. Leaders are making decisions about opening universities and modality of instruction. Read More

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Interdisciplinary management of peripheral arteriovenous malformations: review of the literature and current proceedings.

J Plast Surg Hand Surg 2021 Jul 22:1-10. Epub 2021 Jul 22.

Clinic for Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim - Heidelberg University, Mannheim, Germany.

Arteriovenous malformations (AVMs) are a rare congenital vascular disorder. They represent a fast-flow vascular malformation. Clinically, AVMs present a heterogenous expression and can affect every part of the body. Read More

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Experiences with intestinal failure from an intestinal rehabilitation unit in a country without home parenteral nutrition.

JPEN J Parenter Enteral Nutr 2021 Jul 22. Epub 2021 Jul 22.

Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.

Objective: For the first time, we aimed to report experiences with an intestinal rehabilitation unit (IRU) from a country without home parenteral nutrition (HPN).

Methods: We included all patients with a diagnosis of intestinal failure (IF) since the establishment of our IRU from February 2018 to February 2020. We further report on our protocols for management of enterocutaneous fistulas (ECF), short bowel syndrome (SBS), chronic intestinal pseudo-obstruction and motility disorders. Read More

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Delayed educational services during Covid-19 and their relationships with the mental health of individuals with disabilities.

Halis Sakız

J Community Psychol 2021 Jul 22. Epub 2021 Jul 22.

Department of Educational Sciences, Mardin Artuklu University, Mardin, Turkey.

During the coronavirus disease 2019 (Covid-19) pandemic, individuals with disabilities (IWD), like many others, have not been able to benefit effectively from educational and school-based mental health services, which are vital to achieving mental good health. This study aimed to collect views of IWD about how their mental health was affected by the school closure during Covid-19. Thirty-one IWD were interviewed and data were analyzed thematically. Read More

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Truth is its own reward: Completeness of information, the feeling of truth knowing, and victims' closure.

Br J Soc Psychol 2021 Jul 21. Epub 2021 Jul 21.

Flinders University, Adelaide, South Australia, Australia.

Victims of crime often want the truth about what happened. Yet, how exactly is truth valuable? Commonly, truth is thought to be instrumentally valuable by providing useful knowledge. Truth would be beneficial for victims because specific information may afford re-appraisals or greater understanding. Read More

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On the effect of the inlet configuration for anaerobic digester mixing.

Bioprocess Biosyst Eng 2021 Jul 21. Epub 2021 Jul 21.

Unit of Environmental Engineering, University of Innsbruck, Innsbruck, Austria.

Sludge recirculation mixing in anaerobic digesters is essential for the stable operation of the digestion process. While often neglected, the configuration of the sludge inlet has a substantial influence on the efficiency of the mixing process. The fluid is either injected directly into the enclosed fluid domain or splashes onto the free surface of the slurry flow. Read More

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Predictors of Vape Shops Going out of Business in Southern California.

Tob Regul Sci 2020 May;6(3):187-195

Artur Galimov, Doctoral Student, Institute for Health Promotion and Disease Prevention Research, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA. Ellen Galstyan, Doctoral Student, Institute for Health Promotion and Disease Prevention Research, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA. Sheila Yu, Doctoral Student, Institute for Health Promotion and Disease Prevention Research, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA. Sabrina Smiley, Assistant Professor, Institute for Health Promotion and Disease Prevention Research , Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA. Leah Meza, Project Manager, Institute for Health Promotion and Disease Prevention Research, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA. Lourdes Baezconde-Garbanati, Professor, Institute for Health Promotion and Disease Prevention Research, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA. Jennifer B. Unger, Professor, Institute for Health Promotion and Disease Prevention Research, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA. Steve Sussman, Professor, Institute for Health Promotion and Disease Prevention Research, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA.

Objectives: Vape shops have proliferated in the United States (US) in recent years. As of May 2016, the US Food and Drug Administration (FDA) asserted its authority to regulate electronic nicotine delivery systems. It is critical to understand how these polices have affected the vape shop industry, as the rise and fall of vape shop proliferation has the potential for influencing public health. Read More

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Weight Status and Body Composition Dynamics in Children and Adolescents During the COVID-19 Pandemic.

Front Pediatr 2021 5;9:707773. Epub 2021 Jul 5.

Pediatric Endocrinology and Diabetes Unit, Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, Affiliated With the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

The preventive measures taken in attempt to prevent COVID-19 spread lead to closure of schools and leisure time activities. The impact of the pandemic on pediatric weight status is unclear, reports from around the world predict grave consequences with increasing obesity. We aimed to examine the change in body composition parameters of children and adolescents during the pandemic. Read More

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Cowper's Glands Abscess with Spreading to Adjacent Organs and Tissues with Development of Septic Shock: An Extremely Rare Case.

Res Rep Urol 2021 15;13:501-507. Epub 2021 Jul 15.

Department of Endoscopic Urology, Peoples' Friendship University of Russia (RUDN University), Moscow, Russian Federation.

Background: We present here the first case of Cowper's gland abscess complicated by septic shock and breakthrough of the abscess into the paraurethral region, cavernous body, scrotum, and pararectal tissue.

Case Presentation: A 63-year-old patient was admitted with complaints of temperature increase up to 39°C, pain and enlargement of the perineum and the right half of the scrotum, frequent and difficulty urination, weakness, dizziness, dry mouth, and a sharp deterioration of the general condition. Clinical-laboratory data showed the presence of septic shock with unstable haemodynamics and many concomitant diseases. Read More

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Use of tape for the management of hypertrophic scar development: A comprehensive review.

Scars Burn Heal 2021 Jan-Dec;7:20595131211029206. Epub 2021 Jul 12.

The University of Queensland, School of Health and Rehabilitation Sciences, Brisbane, QLD, Australia.

Introduction: Tapes have been used to aid fresh wound closure. For hypertrophic scars, the use of tapes as a therapy to reduce the mechanical forces that stimulate excessive and long-term scarring is yet to be evaluated. The aim of this comprehensive review was to explore the current clinical application of tapes, as a minimally invasive option, as purposed specifically for the management of hypertrophic scarring, regardless of scar causation. Read More

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Mathematical Model Predicts that Acceleration of Diabetic Wound Healing is Dependent on Spatial Distribution of VEGF-A mRNA (AZD8601).

Cell Mol Bioeng 2021 Aug 15;14(4):321-338. Epub 2021 Jun 15.

Department of Biomedical Engineering, University of Virginia, Charlottesville, VA USA.

Introduction: Pharmacologic approaches for promoting angiogenesis have been utilized to accelerate healing of chronic wounds in diabetic patients with varying degrees of success. We hypothesize that the distribution of proangiogenic drugs in the wound area critically impacts the rate of closure of diabetic wounds. To evaluate this hypothesis, we developed a mathematical model that predicts how spatial distribution of VEGF-A produced by delivery of a modified mRNA (AZD8601) accelerates diabetic wound healing. Read More

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Treatment of Chronic Large and Persistent Macular Hole by a new technique in a Tertiary Care Hospital.

Pak J Med Sci 2021 Jul-Aug;37(4):979-982

Dr. Lubna Feroz, FCPS (Ophth). Ophthalmologist, LRBT Tertiary Eye Care Hospital, Korangi 2 ½, Karachi, Pakistan.

Objective: To assess the anatomical and functional outcomes of treating chronic persistent large macular hole by macular hole hydrodissection technique in a tertiary eye care hospital.

Methods: This interventional case series study was conducted in the Vitreoretinal department of LRBT Tertiary Teaching Eye Hospital, Karachi, from October 2017 to March 2018, with follow-ups till February 2019. The study included eighteen cases of chronic (symptoms of loss of central vision ≥ 2years), persistent (previously failed macular hole surgery), large (aperture diameter of ≥ 400µm) macular hole. Read More

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September 2020

Creativity and Leisure During COVID-19: Examining the Relationship Between Leisure Activities, Motivations, and Psychological Well-Being.

Front Psychol 2021 5;12:609967. Epub 2021 Jul 5.

School of Psychology and Wellbeing, University of Buckingham, Buckingham, United Kingdom.

Social distancing policies have been implemented around the world to reduce the spread of coronavirus disease 2019 (COVID-19). These measures have included temporary restrictions on mass gatherings and the closure of public facilities, limiting the pursuit of leisure activities such as travel while allowing more time for at-home pursuits, including creative activities such as gardening and painting. Previous research has demonstrated the benefits of physical activity for psychological well-being during COVID-19, but less attention has been given to the potential benefits of creative pursuits, such as arts and music. Read More

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A nature-based solution to a landfill-leachate contamination of a confined aquifer.

Sci Rep 2021 Jul 21;11(1):14896. Epub 2021 Jul 21.

Department of Natural Sciences and Environmental Health, Faculty of Technology, Natural Sciences and Maritime Sciences, University of South-Eastern Norway, Gullbringvegen 36, 3800, Bø, Norway.

Remediation of groundwater from landfill contamination presents a serious challenge due to the complex mixture of contaminants discharged from landfills. Here, we show the significance of a nature-based solution to a landfill-contaminated aquifer in southeast Norway. Groundwater physicochemical parameters monitored for twenty-eight years were used as a proxy to infer natural remediation. Read More

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Abdominal wall reconstruction for desmoid tumors following radical resection from the abdominoplasty incision: Case report.

Niger J Clin Pract 2021 Jul;24(7):1100-1102

Department of Surgical Oncology, Saglık Bilimleri University, Adana City Training and Research Hospital, Adana, Turkey.

Desmoid tumours are rare and locally invasive neoplasms that originate from the muscles and their aponeurosis. Incomplete excision causes recurrences; therefore, patients require aggressive resection that essentially entails tumour excision with a clear surgical margin. After radical resection, the resultant wide defect may lead to difficulty in closure of the anterior abdominal wall. Read More

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A survey of mental health professionals in a paediatric hospital during COVID-19.

Clin Child Psychol Psychiatry 2021 Jul 21:13591045211033186. Epub 2021 Jul 21.

UCL Great Ormond Street Institute of Child Health, 11700University College London, London, UK.

Background: There is little understanding of the mental health impact for young people with long-term physical health conditions and mental health professionals' experiences of supporting them during COVID-19. This service evaluation aimed to conduct a survey of the psychological services provided by mental health professionals in a paediatric hospital in relation to COVID-19.

Method: Clinical psychologists and assistant psychologists ( = 76) across the hospital were asked to complete a survey, asking about their perceptions of COVID-19's impact on patients and families and experiences of providing support during COVID-19. Read More

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A new factor involved during childbirth labor: the importance of having a good dental occlusion.

J Biol Regul Homeost Agents 2021 May-Jun;35(3 Suppl. 1):155-166

Faculty of Medicine and Dental Surgery, University of Rome "Sapienza", Rome, Italy.

It is widely recognized that the physiology of childbirth labor largely depends on the interaction between three factors: a) the force generated by uterine contractions; b) the structure and characteristics of the birth canal and c) the fetus. Harmony between these three variables determines the initiation of maternal dynamic phenomena and the establishment of an optimal maternal-fetal balance in which both warrant for a correct delivery timing. The present study considered the above known factors and assessed if any other factor, still not recognized, could also play a role, and eventually modify the timing of delivery during the expulsive period. Read More

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Efficacy of a Novel Medical Adhesive for Sealing Lung Parenchyma: An in vitro Study in Rabbit Lungs.

Eur Surg Res 2021 Jul 21:1-7. Epub 2021 Jul 21.

Department of Thoracic and Cardiovascular Surgery, University Hospital RWTH Aachen, Aachen, Germany.

Introduction: During thoracic resection procedures, complete hemostasis and aerostasis are priorities. A persistent alveolar air leak is associated with increased morbidity and mortality rates. This study aimed to evaluate whether the novel medical adhesive VIVO (Adhesys Medical GmbH Aachen, Germany) is a reliable alternative sealing technique to routine surgical procedures. Read More

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Jasmonic acid and salicylic acid play minor roles in stomatal regulation by CO , abscisic acid, darkness, vapor pressure deficit, and ozone.

Plant J 2021 Jul 21. Epub 2021 Jul 21.

Plant Signal Research Group, Institute of Technology, University of Tartu, Nooruse 1, Tartu, 50411, Estonia.

Jasmonic acid (JA) and salicylic acid (SA) regulate stomatal closure, preventing pathogen invasion into plants. However, to which extent abscisic acid (ABA), SA, and JA interact and what the roles of SA and JA are in stomatal responses to environmental cues remains unclear. Here, by using intact plant gas-exchange measurements in JA and SA single and double mutants, we show that stomatal responsiveness to CO , light intensity, ABA, high vapor pressure deficit, and ozone either did not or for some stimuli only very slightly depended on JA and SA biosynthesis and signaling mutants, including dde2, sid2, coi1, jai1, myc2, and npr1 alleles. Read More

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Reconstruction Technique for Defects of the Cutaneous and Mucosal Lip: V-to-flying-Y Closure.

Cutis 2021 May;107(5):255-257

Beaumont Health Dermatology, Trenton, Michigan.

Repair of a surgical defect following Mohs micrographic surgery can be particularly challenging when it involves free margins of the face. Lip reconstruction falls under this category, requiring careful planning of the repair to avoid not only aesthetic but also functional complications of the oral aperture. Our technique, termed V-to-flying-Y closure, allows for an aesthetically pleasing and functional outcome for repairs of surgical defects that involve both the cutaneous and mucosal lip. Read More

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Comparative Analysis of Safety and Feasibility of Suture Versus Sutureless Pediatric Cataract Surgery.

J Pediatr Ophthalmol Strabismus 2021 Jul-Aug;58(4):246-253. Epub 2021 Jul 1.

Purpose: To compare the safety, feasibility, and outcomes of clear corneal cataract surgery with or without sutures in children (2 to 8 years old) with congenital or developmental cataracts.

Methods: One hundred seventy consecutive eligible eyes with pediatric cataracts were randomized into treatment groups depending on closure of clear corneal incisions: suture group and sutureless hydroclosure group (sutureless group). Patients were evaluated on days 1, 7, 30, and 90 postoperatively, with an emphasis on wound leakage from incisions and complications. Read More

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