78,041 results match your criteria clinical radiological

Primary squamous cell carcinoma, breast: A challenging diagnosis.

Cancer Rep (Hoboken) 2021 May 5:e1391. Epub 2021 May 5.

Department of Endocrine surgery, King George's Medical University, Lucknow, India.

Background: Primary squamous cell carcinoma of the breast is an extremely rare malignancy constituting less than 0.1% of all breast cancers with very few cases reported in literature. It is an aggressive, triple-hormone negative tumor, and its appropriate management is still debated. Read More

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Use of a Double Reverse Traction Repositor versus a Traction Table for the Treatment of Intertrochanteric Femur Fractures: A Comparative Study.

Orthop Surg 2021 May 5. Epub 2021 May 5.

Department of Orthopaedic Surgery, The Second Xiangya Hospital, Central South University, Changsha, China.

Objective: The aim of the present study was to compare the clinical results for unstable femoral intertrochanteric fractures treated with a double reverse traction repositor (DRTR) and those treated using a traction table with the Asia proximal femoral nail antirotation (PFNA-II).

Methods: A retrospective study was performed including 95 patients with AO/OTA type 31-A2 and 31-A3 unstable femoral intertrochanteric fractures who underwent DRTR or traction table-facilitated PFNA-II nailing from April 2015 to December 2018 in our traumatic center. Demographics, duration of operation, blood loss, part loading time after surgery, fracture healing time, and early and late complications were assessed. Read More

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The role of 99mTc-antigranulocyte SPECT/CT in community-acquired diabetic foot osteomyelitis: A clinical experience.

Curr Diabetes Rev 2021 May 3. Epub 2021 May 3.

Department of Orthopedic Surgery, Balgrist University Hospital, Zurich, Switzerland.

Background: Magnetic resonance imaging (MRI) is the actual gold standard for the radiological diagnosis of diabetic foot osteomyelitis (DFO).

Materials And Methods: However, MRI is not always available, and many patients have contraindications. We evaluate the clinical value of 99mTc-antigranulocyte SPECT/CT (AGS) in eight DFO patients who underwent MRI before. Read More

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Encephalitis with autoantibodies against the glutamate kainate receptors GluK2.

Ann Neurol 2021 May 5. Epub 2021 May 5.

Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.

Objective: To report the identification of antibodies against the glutamate kainate receptor subunit 2 (GluK2-abs) in patients with autoimmune encephalitis, and describe the clinical-immunological features and antibody effects.

Methods: Two sera from 8 patients with similar rat brain immunostaining were used to precipitate the antigen from neuronal cultures. A cell-based assay (CBA) with GluK2-expressing HEK293 cells was used to assess 596 patients with different neurological disorders, and 23 healthy controls. Read More

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Magnetic resonance imaging of the inner ear in the diagnostics of Ménière's disease.

Otolaryngol Pol 2020 Dec;75(2):1-8

Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Warsaw, Poland; Head: Prof. Kazimierz Niemczyk MD PhD.

Ménière's disease is characterized by sudden episodes of vertigo accompanied by tinnitus and/or feeling of fullness in the ear as well as fluctuating sensorineural hearing loss. Despite numerous studies, the etiology of this disease remains unknown. However, the enlargement of the inner ear's endolymphatic spaces, referred to as endolymphatic hydrops, is considered the underlying condition. Read More

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December 2020

Talk to us! Communication is a key factor in improving the comfort of MRI research participants.

Health Expect 2021 May 5. Epub 2021 May 5.

National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham, UK.

Context: Magnetic resonance imaging (MRI) is an invaluable diagnostic and research tool. Having an MRI scan is not always comfortable and may deter people from taking part in MRI research. Maximizing comfort during scanning will improve participants' experiences and image quality. Read More

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Clinical performance of implant crowns with customized zirconia abutments. A prospective cohort study with a 4.5- to 8.8-year follow-up.

Clin Oral Implants Res 2021 May 4. Epub 2021 May 4.

Professor emeritus, Department of Reconstructive Dentistry and Gerodontology, School of Dental Medicine, University of Bern, Switzerland.

Objective: To assess the clinical and esthetic outcomes and patient satisfaction of screw-retained one-piece implant crowns fabricated with zirconia abutments after a 4.5- to 8.8-years follow-up. Read More

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Clinical prediction of genotypes in hypertrophic cardiomyopathy: A Systematic Review.

Eur J Clin Invest 2021 May 4:e13593. Epub 2021 May 4.

Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom; and Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.

Introduction: Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac condition and the most common cause of sudden cardiac death (SCD) in patients below the age of 35. Genetic testing is a vital part of HCM diagnostics, yet correlation with clinical phenotypes remains complex. Identifying clinical predictors of informative genetic testing may prevent unnecessary investigations and improve cost-effectiveness of services. Read More

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Prognostic value of F-FDG PET/CT with texture analysis in patients with rectal cancer treated by surgery.

Ann Nucl Med 2021 May 4. Epub 2021 May 4.

Department of Surgery, National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan.

Purpose: The aim of this study was to evaluate the ability of texture analysis using pretreatment F-FDG PET/CT to predict prognosis in patients with surgically treated rectal cancer.

Methods: We analyzed 94 patients with pathologically proven rectal cancer who underwent pretreatment F-FDG PET/CT and were subsequently treated with surgery. The volume of interest of the primary tumor was defined using a threshold of 40% of the maximum standardized uptake value (SUVmax), and conventional (SUVmax, metabolic tumor volume [MTV], total lesion glycolysis [TLG]) and textural PET features were extracted. Read More

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Utility of a Suture-Mediated Closure System for Large Bore Arterial Access During Challenging Liver Intra-Arterial Catheters Implantation.

Cardiovasc Intervent Radiol 2021 May 4. Epub 2021 May 4.

Department of Radiology, Institut Paoli Calmettes, 232 Boulevard Sainte Marguerite, 13009, Marseille, France.

Purpose: To describe and study the utility of vascular suture-mediated closure systems for large bore arterial access during challenging implantation of liver intra-arterial catheters taking as a reference the conventional procedure involving patients without challenging anatomy.

Materials And Methods: Between January 2017 and January 2019, 61 consecutive patients underwent 65 intra-arterial catheter IAC implantations for colorectal cancer. Twenty-three procedures (35%) considered by the operators with challenging coeliac trunk angulations were treated using a vascular suture technique where a 6-F introducer was used, the other patients were treated with a conventional 4F access technique. Read More

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Sinonasal Extramedullary Plasmacytoma With Rare Osteolytic Lesions.

Cureus 2021 Mar 31;13(3):e14220. Epub 2021 Mar 31.

Orthopedics, General Hospital of Patras, Patras, GRC.

Plasmacytomas are malignant tumors characterized by abnormal monoclonal proliferation of plasma cells. They originate either from bone or soft tissue and could be primary or a part of a systemic process during the course of multiple myeloma. Extramedullary plasmacytomas (EPs) in the sinonasal tract or nasopharynx are rare and mostly presented as case reports. Read More

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Intraparenchymal subependymoma: Case report and literature review.

Surg Neurol Int 2021 14;12:154. Epub 2021 Apr 14.

Department of Neurosurgery, Antonio Pedro University Hospital, Brazil.

Background: Intracranial subependymomas are rare slow-growing benign tumors typically located in the ventricular system, accounting for 0.07-0.7% of all intracranial neoplasms. Read More

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Parotid Ewing's sarcoma: Extra-skeletal uncommon condition.

Ann Med Surg (Lond) 2021 May 13;65:102304. Epub 2021 Apr 13.

Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco.

Introduction: The parotid gland is a very rare location of Ewing's sarcoma. Its clinical and radiological manifestations are atypical. Its management is based on a multidisciplinary approach to improve prognosis and survival. Read More

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2-step deep learning model for landmarks localization in spine radiographs.

Sci Rep 2021 May 4;11(1):9482. Epub 2021 May 4.

IRCCS Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milan, Italy.

In this work we propose to use Deep Learning to automatically calculate the coordinates of the vertebral corners in sagittal x-rays images of the thoracolumbar spine and, from those landmarks, to calculate relevant radiological parameters such as L1-L5 and L1-S1 lordosis and sacral slope. For this purpose, we used 10,193 images annotated with the landmarks coordinates as the ground truth. We realized a model that consists of 2 steps. Read More

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[Pulse oximetry: Role in the COVID-19 patient at home].

Semergen 2021 Apr 20. Epub 2021 Apr 20.

Centro de Salud Joaquín Elizalde, Logroño. Servicio Riojano de Salud. Grupo de Trabajo de Hipertensión Arterial y Enfermedad Cardiovascular de SEMERGEN, La Rioja, España.

COVID-19 behaves like a heterogeneous disease. Some patients may develop dyspnea-free hypoxemia during its evolution (silent hypoxemia). Pulse oximetry plays a crucial role in detecting hypoxemia in these patients, especially when they remain at home. Read More

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Multidisciplinary corroboration in differentiation syndrome: a case report.

J Med Case Rep 2021 May 5;15(1):226. Epub 2021 May 5.

Department of Pediatric ICU, Tata Medical Center, 14 MAR (E-W), New Town, Rajarhat, Kolkata, 700160, West Bengal, India.

Background: Differentiation syndrome (DS) is a life-threatening complication that may be seen in patients with acute promyelocytic leukaemia undergoing induction therapy with all-trans retinoic acid or arsenic trioxide. It can lead to severe inflammatory response syndrome and shock if adequate measures are not taken immediately. The radiological features of lung nodules with changes in ground-glass opacity can represent DS. Read More

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A spacer infection by Candida albicans secondary to a Staphylococcus capitis prosthetic joint infection: a case report.

BMC Infect Dis 2021 May 4;21(1):416. Epub 2021 May 4.

IRCCS Istituto Ortopedico Galeazzi, Laboratory of Clinical Chemistry and Microbiology, Via R. Galeazzi 4, 20161, Milan, Italy.

Background: Prosthetic joint infection (PJI) is one of the most feared complications following total arthroplasty surgeries. Gram-positive bacteria are the most common microorganisms implicated in PJIs, while infections mediated by fungi only account for 1% of cases. When dealing with PJIs, a two-stage revision arthroplasty is widely used. Read More

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Theranostics in Oncology-Thriving, Now More than Ever.

Diagnostics (Basel) 2021 Apr 29;11(5). Epub 2021 Apr 29.

The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

Tracing its roots back to the 1940s, theranostics in nuclear oncology has proved successful mainly due to the beneficial effects of image-guided therapeutic concepts for patients afflicted with a variety of different cancers. The majority of these treatments are not only characterized by substantial prolongation of progression-free and overall survival, but are also generally safe, rendering theranostic agents as an attractive treatment option in various clinical scenarios in oncology. In this Special Issue , nine original articles from around the globe provide further evidence on the use of the theranostic concept for neuroendocrine neoplasm (NEN), prostate cancer (PC), meningioma, and neuroblastoma. Read More

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Forensic Application of Monoclonal Anti-Human Glycophorin A Antibody in Samples from Decomposed Bodies to Establish Vitality of the Injuries. A Preliminary Experimental Study.

Healthcare (Basel) 2021 Apr 29;9(5). Epub 2021 Apr 29.

Legal Medicine Division, Sant'Andrea University Hospital, 00189 Rome, Italy.

Glycophorins are an important group of red blood cell (RBC) transmembrane proteins. Monoclonal antibodies against GPA are employed in immunohistochemical staining during post-mortem examination: Through this method, it is possible to point out the RBC presence in tissues. This experimental study aims to investigate anti-GPA immunohistochemical staining in order to evaluate the vitality of the lesion from corpses in different decomposition state. Read More

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Metabolic Signatures Associated with Severity in Hospitalized COVID-19 Patients.

Int J Mol Sci 2021 Apr 30;22(9). Epub 2021 Apr 30.

Integrative Pharmacology and Systems Neuroscience Research Group, Neurosciences Research Program, IMIM-Institut Hospital del Mar d'Investigacions Mèdiques, 08003 Barcelona, Spain.

The clinical evolution of COVID-19 pneumonia is poorly understood. Identifying the metabolic pathways that are altered early with viral infection and their association with disease severity is crucial to understand COVID-19 pathophysiology, and guide clinical decisions. This study aimed at assessing the critical metabolic pathways altered with disease severity in hospitalized COVID-19 patients. Read More

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Applying MRI Intensity Normalization on Non-Bone Tissues to Facilitate Pseudo-CT Synthesis from MRI.

Diagnostics (Basel) 2021 Apr 30;11(5). Epub 2021 Apr 30.

Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.

This study aimed to facilitate pseudo-CT synthesis from MRI by normalizing MRI intensity of the same tissue type to a similar intensity level. MRI intensity normalization was conducted through dividing MRI by a shading map, which is a smoothed ratio image between MRI and a three-intensity mask. Regarding pseudo-CT synthesis from MRI, a conversion model based on a three-layer convolutional neural network was trained and validated. Read More

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Imaging characteristics of nontuberculous mycobacterial pulmonary nodules.

Rom J Intern Med 2021 Apr 30. Epub 2021 Apr 30.

Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba-Mito Kyodo General Hospital, Miya-macho 3-2-7, Mito-city, Ibaraki, 310-0015, Japan.

: Nontuberculous mycobacteriosis (NTM) of the lungs can develop nodules. In order to clarify some of the characteristics of lung NTM nodules, we examined volume doubling time (VDT) and maximum standardized uptake value (SUVmax) in positron emission tomography (PET) of pathologically diagnosed NTM nodules.: From November 2012 to August 2018, clinical and radiological information were retrospectively investigated in 8 patients who were surgically resected and diagnosed as NTM. Read More

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Beaming in the Charcot foot: A case series with 12-month minimum follow-up.

Foot (Edinb) 2021 Apr 18;47:101814. Epub 2021 Apr 18.

Department of Orthopaedics and Trauma Surgery, 'Gregorio Marañón' University Hospital, Madrid, Spain. Electronic address:

Background: Charcot neuropathic arthropathy is a progressive degeneration of the weightbearing joints of the foot induced by denervation and disturbance of sensorial perception. This entity clinically behaves as a destructive fast-progressive arthropathy, resulting in loss of independent walking and often requiring amputation of the leg. This study analyzes our experience with midfoot realignment arthrodesis and stabilization by intramedullary beaming in patients with Charcot diabetic foot as a limb-sparing procedure. Read More

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Matched retrospective analysis of three different fixation devices for chevron osteotomy.

Foot (Edinb) 2021 Jan 21;47:101779. Epub 2021 Jan 21.

Department of Orthopaedics of Herz Jesu Krankenhaus Vienna, Baumgasse 20A, 1030 Wien, Austria.

Chevron osteotomy with consecutive fixation is a commonly performed operative treatment option for hallux valgus deformities. The present retrospective study aims to compare the clinical and radiological outcome of novel bioabsorbable magnesium screw fixation with metal screw and Kirschner wire fixation. Eighteen matched triplets were assembled according to the following criteria: female gender, age difference less than 5 years, date of operation within 4 months, difference in preoperative intermetatarsal angle less than 5°, and equal experience of the first and second surgeon. Read More

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January 2021

Partial nephrectomy in frail patients: Benefits of robot-assisted surgery.

Surg Oncol 2021 Apr 22;38:101588. Epub 2021 Apr 22.

Cancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montreal Health Center, Montreal, Quebec, Canada.

Background: To compare the effect of robot-assisted (RAPN) vs. open (OPN) partial nephrectomy on short-term postoperative outcomes and total hospital charges in frail patients with non-metastatic renal cell carcinoma (RCC).

Methods: Within the National Inpatient Sample database we identified 2745 RCC patients treated with either RAPN or OPN between 2008 and 2015, who met the Johns Hopkins Adjusted Clinical Groups frailty-defining indicator criteria. Read More

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Phenotypic and genotypic spectrum of CTSK variants in a cohort of Twenty-Five Indian patients with Pycnodysostosis.

Eur J Med Genet 2021 May 1:104235. Epub 2021 May 1.

Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow. Electronic address:

Background: Pycnodysostosis is an autosomal recessive skeletal dysplasia with easily recognizable clinical features and marked molecular heterogeneity. In this study, we explored the clinical and molecular spectrum of 25 Indian patients with pycnodysostosis from 20 families.

Methods: Clinical information was collected on a predesigned clinical proforma. Read More

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Implant therapy in the rehabilitation of mandibular arteriovenous malformations.

J Oral Implantol 2021 May 4. Epub 2021 May 4.

Aix-Marseille Universite Faculte de Medecine Oral surgery 264 Rue Saint-Pierre FRANCE Marseille 13385 Aix-Marseille Universite Faculte de Medecine.

Purpose: Mandibular arteriovenous malformations are rare congenital malformations which require multidisciplinary care. Implant-supported rehabilitation of significant bone defect after embolization and resection is poorly described in the literature.

Clinical Report: We present the case of a 24 year-old patient with a right sided mandibular arteriovenous malformations diagnosed after massive hemorrhage and treated by embolization and resection surgery. Read More

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Lenvatinib in Patients With Advanced Grade 1/2 Pancreatic and Gastrointestinal Neuroendocrine Tumors: Results of the Phase II TALENT Trial (GETNE1509).

J Clin Oncol 2021 May 4:JCO2003368. Epub 2021 May 4.

Clinical Oncology Unit, AOU Careggi, Firenze, Italy and Department of Experimental and Clinical Medicine, University of Firenze, Firenze, Italy.

Purpose: Approved systemic therapies for advanced gastroenteropancreatic neuroendocrine tumors (GEP-NETs) have shown limited capacity to reduce tumor burden and no antitumor activity after progression to targeted agents (TAs). We investigated the efficacy and safety of lenvatinib in patients with previously treated advanced GEP-NETs.

Patients And Methods: This was a multicenter, single-arm, open-label, phase II trial with two parallel cohorts (ClinicalTrials. Read More

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