298 results match your criteria clinical dermatoscopic

Melanocytic lesions ≤ 6mm: Prospective series of 481 melanocytic trunk and limb lesions in Brazil.

PLoS One 2021 8;16(6):e0252162. Epub 2021 Jun 8.

National Cancer Institute, Rio de Janeiro, Brazil.

Early diagnosis when melanoma is still small and thin is essential for improving mortality and morbidity. However, the diagnosis of small size melanoma might be particularly difficult, not only clinically but also dermoscopically. This study aimed to define clinical and dermatoscopic parameters in the diagnosis of suspicious pigmented cutaneous lesions with a diameter of ≤ 6mm and determine the sensitivity, specificity, positive and negative predictive values as well as the accuracy of each clinical and dermatoscopic criterion. Read More

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Collective human intelligence outperforms artificial intelligence in a skin lesion classification task.

J Dtsch Dermatol Ges 2021 Jun 7. Epub 2021 Jun 7.

Department of Dermatology, University of Heidelberg, Heidelberg, Germany.

Background And Objectives: Convolutional neural networks (CNN) enable accurate diagnosis of medical images and perform on or above the level of individual physicians. Recently, collective human intelligence (CoHI) was shown to exceed the diagnostic accuracy of individuals. Thus, diagnostic performance of CoHI (120 dermatologists) versus individual dermatologists versus two state-of-the-art CNN was investigated. Read More

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Diagnostic Algorithm for Conjunctival Melanocytic Lesions.

Anticancer Res 2021 Jun;41(6):3161-3167

Department of Ophthalmology and Ocular Oncology, Faculty of Medicine, Jagiellonian University Medical College, Krakow, Poland;

Background/aim: This study aimed to develop an algorithm allowing the differentiation between conjunctival melanoma and other melanocytic infiltrations of the conjunctiva, on the basis of a dermatoscopic examination.

Patients And Methods: A total of 160 conjunctival pigmented lesions were studied (40 melanomas and 120 non-melanoma conjunctival infiltrations). The clinical characteristics of the tumours were assessed with the use of dermatoscopic characteristics as described by Kittler, and with taking into consideration the typical characteristics of conjunctival lesions. Read More

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Defining the Criteria for Reflex Testing for Mutations in Cutaneous Melanoma Patients.

Cancers (Basel) 2021 May 10;13(9). Epub 2021 May 10.

Division of Dermatology, McGill University, Montreal, QC H3A 0G4, Canada.

Targeted therapy has been developed through an in-depth understanding of molecular pathways involved in the pathogenesis of melanoma. Approximately ~50% of patients with melanoma have tumors that harbor a mutation of the oncogene. Certain clinical features have been identified in -mutated melanomas (primary lesions located on the trunk, diagnosed in patients <50, visibly pigmented tumors and, at times, with ulceration or specific dermatoscopic features). Read More

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Dark corner artefact and diagnostic performance of a market-approved neural network for skin cancer classification.

J Dtsch Dermatol Ges 2021 May 10. Epub 2021 May 10.

Department of Dermatology, University of Heidelberg, Heidelberg, Germany.

Background And Objectives: Convolutional neural networks (CNN) have proven dermatologist-level performance in skin lesion classification. Prior to a broader clinical application, an assessment of limitations is crucial. Therefore, the influence of a dark tubular periphery in dermatoscopic images (also called dark corner artefact [DCA]) on the diagnostic performance of a market-approved CNN for skin lesion classification was investigated. Read More

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Clinical and dermatoscopic features of lichen planus balanoposthitis.

Clin Exp Dermatol 2021 Apr 29. Epub 2021 Apr 29.

Department of, Internal Diseases, Riga Stradins University, Riga, Latvia.

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Dermatoscopy and Reflective Confocal Microscopy for Facial Seborrheic Keratosis, Verruca Plana, and Nevus Pigmentosus.

J Coll Physicians Surg Pak 2021 Apr;30(4):450-454

Department of Dermatology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.

Objective: To describe the features of facial seborrheic keratosis, verruca plana, and nevus pigmentosus by dermatoscopy and reflective confocal microscope (RCM).

Study Design: Cross-sectional observational study.

Place And Duration Of Study: Dermatology Department of The Affiliated Hospital of Xuzhou Medical University from January 2017 to January 2019. Read More

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Evaluation of dermatoscopic criteria for early detection of squamous cell carcinoma arising on an actinic keratosis.

J Am Acad Dermatol 2021 Apr 20. Epub 2021 Apr 20.

Second Dermatology Department, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Background: Advanced squamous cell carcinoma (SCC) can be discriminated easily from actinic keratosis (AK) based on clinical and dermatoscopic features. However, at the initial stage of dermal invasion, SCC might still be clinically flat and discrimination from AK remains challenging, even with the addition of dermatoscopy.

Objective: The aim of this study was to investigate the clinical and dermatoscopic criteria that could suggest early invasion and serve as potent predictors to discriminate early SCC from AK. Read More

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Melasma treatment: a systematic review.

J Dermatolog Treat 2021 Apr 14:1-39. Epub 2021 Apr 14.

Plastic and Reconstructive Surgery Unit, Campus Bio-Medico University of Rome, Rome, Italy.

Melasma is a common chronic refractory disorder of pigmentation affecting people with darker skin types. Overall prevalence varies between 8.8% and 40%, depending on the ethnicity of the population and the geographical area. Read More

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Effects of metformin on experimentally induced acne on rabbit ear.

Exp Dermatol 2021 Apr 13. Epub 2021 Apr 13.

Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Evidence for the effectiveness of metformin in the treatment of acne is limited. To assess its efficacy, comedones were experimentally induced in young New Zealand rabbit ear using Isopropyl Myristate (IM) followed by metformin treatment (30 mg/kg bodyweight) for 60 days with continued IM application. In another group, to check whether metformin pre-treatment affects subsequent comedone development by IM, metformin was given for 14 days and then withdrawn (14 days) followed by comedone development with IM and metformin treatment. Read More

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Evaluation of relationship between antihypertensive drug usage and dermatoscopic features in patients with keratinizing skin cancer.

Dermatol Ther 2021 Apr 11:e14957. Epub 2021 Apr 11.

Department of Dermatology, Health Science University, Ankara Oncology Training and Research Hospital, Ankara, Turkey.

Keratinizing skin cancers including actinic keratoses (AK), in situ squamous cell carcinoma/Bowen's disease/intraepidermal carcinoma (IEC), invasive cutaneous squamous cell carcinoma (cSCC) and keratoacanthoma share similar dermatoscopic features and also reveal different patterns that assist in their diagnosis. Recently epidemiological studies reveal the association between antihypertensive drugs and skin cancer risk, especially cSCC. This study aims to determine the dermatoscopic features of keratinizing skin cancer in patients using antihypertensive drug and compare with non-users. Read More

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Unusual Clinical Presentation of Giant Extragenital Condyloma.

Acta Dermatovenerol Croat 2020 Dec;28(7):240-241

Andrija Jovic, MD, Clinical Center of Nis, Clinic of Dermatovenereology , Bulevar Zorana Djindjica 48, Nis, Serbia;

Dear editor, Condylomata accuminatum (CA) is a human papillomavirus (HPV) related sexually transmitted infection (STI), clinically characterized by solitary or even clustered dark red or pink lesions solely affecting the anogenital area (1). CA involving the extragenital, non-mucosal skin has been sporadically reported (2-4). Diagnosis of CA is usually straightforward when the lesions are located on the anogenital area. Read More

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December 2020

Basal cell carcinoma and dermal nevi of the face: comparison of localization and dermatoscopic features.

Int J Dermatol 2021 Apr 7. Epub 2021 Apr 7.

Dermatology Clinic, Maggiore Hospital of Trieste, Trieste, Italy.

Background: Basal cell carcinoma (BCC) and dermal nevi located on the face can easily be confused on clinical examination. Little is known about the different preferential localizations of these entities, and a systematic analysis of dermatoscopic features for differential diagnosis is lacking.

Methods: Clinical and dermatoscopic images of BCCs and dermal nevi were retrospectively evaluated to study their relation to various face anatomical areas, BCC histotype, classic and nonclassic dermatoscopic BCC criteria, as well as typical dermatoscopic criteria for dermal nevi. Read More

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The Role in Teledermoscopy of an Inexpensive and Easy-to-Use Smartphone Device for the Classification of Three Types of Skin Lesions Using Convolutional Neural Networks.

Diagnostics (Basel) 2021 Mar 5;11(3). Epub 2021 Mar 5.

Department of Health Science, University of Eastern Piedmont, Via Solaroli 17, 28100 Novara, Italy.

Background: The use of teledermatology has spread over the last years, especially during the recent SARS-Cov-2 pandemic. Teledermoscopy, an extension of teledermatology, consists of consulting dermoscopic images, also transmitted through smartphones, to remotely diagnose skin tumors or other dermatological diseases. The purpose of this work was to verify the diagnostic validity of images acquired with an inexpensive smartphone microscope (Nurugo), employing convolutional neural networks (CNN) to classify malignant melanoma (MM), melanocytic nevus (MN), and seborrheic keratosis (SK). Read More

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A Clinicopathological Study of Skin Tumors from a Tertiary Care Centre in North India.

Indian Dermatol Online J 2021 Jan-Feb;12(1):66-71. Epub 2021 Jan 16.

Department of Pathology, DMCH, Ludhiana, Punjab, India.

Background: There is a huge spectrum of skin tumors which can be confused clinically with malignancies, particularly when they are pigmented or inflamed, and histopathological examination of a biopsy specimen is required to establish a definitive diagnosis and to facilitate appropriate intervention and follow up.

Aim: To evaluate all skin tumors and categorize them according to their origin.

Methods: The present study was conducted over a period of 4 years (July 1, 2013 to June 31, 2017) comprising of 1. Read More

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January 2021

Dermatoscopic Features of Pigmentary Diseases in Ethnic Skin.

Indian Dermatol Online J 2021 Jan-Feb;12(1):24-33. Epub 2021 Jan 16.

Department of Dermatology, S Nijalingappa Medical College, Bagalkot, Karnataka, India.

Dermatoscopy is a non-invasive, handy tool, which is increasingly being used in diagnosis and prognostication of pigmentary dermatoses. Dermatoscopic changes in pigmentary pattern, scaling, and vasculature help us to differentiate among the myriad of hypo and hyper pigmentary diseases. This review gives a brief overview of the dermatoscopic features of pigmentary diseases, which are commonly encountered in clinical practice. Read More

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January 2021

[Scabies-clinical resistance to permethrin therapy : Case reports and a critical discussion of current treatment recommendations].

Hautarzt 2021 Mar 15. Epub 2021 Mar 15.

Gemeinschaftspraxis für Dermatologie, Venerologie, Allergologie und Proktologie, Hautzentrum Wuppertal, Hauptstr. 36, 42349, Wuppertal, Deutschland.

Scabies is a contagious disease with increasing frequency. This is confirmed by data from insurance companies as well as increased search queries on Google. There is a controversial discussion in the scientific literature whether the mite has become resistant to standard therapy with permethrin. Read More

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Evaluation of Erythema Severity in Dermatoscopic Images of Canine Skin: Erythema Index Assessment and Image Sampling Reliability.

Sensors (Basel) 2021 Feb 11;21(4). Epub 2021 Feb 11.

Department of Clinical Sciences, College of Veterinary Medicine, NC State University, 1060 William Moore Dr., Raleigh, NC 27607, USA.

The regular monitoring of erythema, one of the most important skin lesions in atopic (allergic) dogs, is essential for successful anti-allergic therapy. The smartphone-based dermatoscopy enables a convenient way to acquire quality images of erythematous skin. However, the image sampling to evaluate erythema severity is still done manually, introducing result variability. Read More

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February 2021

Congenital melanocytic naevi: An up-to-date overview.

Australas J Dermatol 2021 May 16;62(2):e178-e191. Epub 2021 Feb 16.

Department of Dermatology, Robert Wood Johnson Medical Centre, Rutgers University, New Brunswick, New Jersey, USA.

Congenital melanocytic naevi are hamartomas of the neuroectoderm caused by genetic mosaicism. Congenital melanocytic naevi are seen in 1-6% of all live births and commonly classified based on the projected size in adults. Congenital melanocytic naevi appear in different colours, shapes, and sizes, and occasionally present with complications. Read More

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Dermatoscopic findings and dermatopathological correlates in clinical variants of actinic keratosis, Bowen's disease, keratoacanthoma, and squamous cell carcinoma.

Dermatol Ther 2021 May 7;34(3):e14877. Epub 2021 Mar 7.

Faculty of Medicine, Dermatology Department, Ankara University, Ankara, Turkey.

Non-melanoma skin cancer (NMSC), predominantly squamous cell carcinoma (SCC) and basal cell carcinoma, is increasing worldwide. Dermatoscopy, which is one of the non-invasive diagnostic techniques, is important for early diagnosis of NMSC. In this study we aimed to determine dermatoscopic features of keratinocyte derived tumors including actinic keratosis (AK), Bowen's disease (BD), keratoacanthoma (KA), and SCC and correlate the dermatoscopic findings with pathology. Read More

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Adversarial attack on deep learning-based dermatoscopic image recognition systems: Risk of misdiagnosis due to undetectable image perturbations.

Medicine (Baltimore) 2020 Dec;99(50):e23568

Clinical Informatic Department.

Deep learning algorithms have shown excellent performances in the field of medical image recognition, and practical applications have been made in several medical domains. Little is known about the feasibility and impact of an undetectable adversarial attacks, which can disrupt an algorithm by modifying a single pixel of the image to be interpreted. The aim of the study was to test the feasibility and impact of an adversarial attack on the accuracy of a deep learning-based dermatoscopic image recognition system. Read More

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December 2020

Dermatoscopy of combined blue nevi: a multicentre study of the International Dermoscopy Society.

J Eur Acad Dermatol Venereol 2021 Apr 5;35(4):900-905. Epub 2021 Jan 5.

Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Vienna, Austria.

Background: Combined blue nevi (CBN) may mimic melanoma and are relatively often biopsied for diagnostic reasons.

Objective: To better characterize CBN and to compare it with melanoma.

Methods: We collected clinical and dermatoscopic images of 111 histologically confirmed CBN and contrasted their dermatoscopic characteristics with 132 partly blue coloured melanomas. Read More

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Clinical and dermatoscopic characteristics of lichen planus-like keratosis in a West-Asian population.

Australas J Dermatol 2021 Feb 17;62(1):e55-e61. Epub 2020 Nov 17.

Primary Care Clinical Unit, Faculty of Medicine, The University of Queensland, Herston, Australia.

Background/objective: The clinical and dermatoscopic features of lichen planus-like keratosis have been described but the characteristics of this entity in a West-Asian population are not known.

Methods: We retrospectively analysed 82 histopathologically verified cases of lichen planus-like keratosis from 81 patients from Iran and Turkey.

Results: The majority of lichen planus-like keratoses were macules (61% n = 50), clinically pigmented (67. Read More

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February 2021

Artificial intelligence for melanoma diagnosis: a review of published studies until 2020.

Philipp Tschandl

G Ital Dermatol Venereol 2020 Nov 12. Epub 2020 Nov 12.

Department of Dermatology, Medical University of Vienna, Vienna, Austria -

Convolutional neural networks (CNN) have shown unprecedented accuracy in digital image analysis, which can be harnessed for melanoma recognition through automated evaluation of clinical and dermatoscopic images. In experimental studies, modern CNN architectures perform single image analysis at the level of dermatologists and domain-experts, also for multi-class predictions including a multitude of possible diagnoses. This may not necessarily translate to good clinical performance, and reliable randomised controlled prospective clinical trials for modern CNNs are essentially missing. Read More

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November 2020

Folliculotropism in head and neck lentigo maligna and lentigo maligna melanoma.

J Dtsch Dermatol Ges 2021 02 9;19(2):223-229. Epub 2020 Nov 9.

Dermatology Department, University of Modena and Reggio Emilia, Modena, Italy.

Background: Lentigo maligna (LM) and lentigo maligna-melanoma (LMM) are histotypes of melanoma arising in skin with cumulative solar radiation damage. The extension of atypical melanocytes to the hair follicle (folliculotropism) is a histopathological feature of LM/LMM. Its role has not been totally clarified, but it may be correlated to treatment response in LM or to progression in LMM. Read More

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February 2021

The dermatoscopic spectrum of cutaneous lupus erythematosus: A retrospective analysis by clinical subtype with clinicopathological correlation.

Dermatol Ther 2020 11 18;33(6):e14514. Epub 2020 Nov 18.

First Department of Dermatology, Aristotle University of Thessaloniki, Thessaloniki, Greece.

The skin is the most common organ of involvement during the course of lupus erythematosus (LE). The literature data concerning the dermatoscopic patterns of the different clinical variants of cutaneous LE (CLE), namely chronic (CCLE), subacute (SCLE), and acute (ACLE), are scarce. To determine the dermatoscopic spectrum of CLE and to correlate the dermatoscopic features with the histological findings. Read More

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November 2020

Use of Artificial Intelligence in Dermatology.

Indian J Dermatol 2020 Sep-Oct;65(5):352-357

Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal, India.

Artificial intelligence (AI) has emerged as a major frontier in computer science research. Although AI has been available for some time and found its application in many fields of medicine, its use in dermatology is comparatively new and limited. A sound understanding of the concepts of AI is essential for dermatologists as skin conditions with their abundant clinical and dermatoscopic data and images can potentially be the next big thing in the application of AI in medicine. Read More

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November 2020

Clinical, trichoscopy, and light microscopic findings in hypohidrotic ectodermal dysplasia: Report of 21 patients and a review of the literature.

Pediatr Dermatol 2021 Mar 21;38(2):442-448. Epub 2020 Oct 21.

Dermatology Department, Instituto Nacional de Pediatría, Coyoacán, Mexico City, Mexico.

Introduction: Hypohidrotic ectodermal dysplasia (HED) is a genetic condition typified by alterations in skin structures including sweat glands, hair, nails, and teeth. Hair findings in HED have been poorly characterized in larger series.

Objective: To characterize scalp and hair findings of patients with HED clinically and with trichoscopy and light microscopy. Read More

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Fingerprint loss in two patients with Sézary syndrome: clinical and dermatoscopic evaluation.

J Dtsch Dermatol Ges 2020 10 8;18(10):1184-1185. Epub 2020 Oct 8.

Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, and Weill Cornell Medicine, New York, NY, USA.

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October 2020