33,383 results match your criteria clamping techniques


Suppressive effect erythropoietin on oxidative stress by targeting AMPK/Nox4/ROS pathway in renal ischemia reperfusion injury.

Transpl Immunol 2022 Jan 11:101537. Epub 2022 Jan 11.

Department of Endocrinology and Metabolism, First Affiliated Hospital of Nanchang University, Nanchang 330006, China. Electronic address:

Objective: To explore the effect of erythropoietin (EPO) on the AMP-activated protein kinase (AMPK)/nicotinamide adenine dinucleotide phosphatase oxidase 4 (NOX4) signaling pathway during renal ischemia reperfusion injury (RIRI) in rats.

Methods: A rat model of RIRI was established by clamping the left renal pedicle and removing the right kidney. The rats in the sham group did not have their left renal pedicle clamped. Read More

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January 2022

Comparison of Three Different Cord Clamping Techniques Regarding Oxidative-antioxidative Capacity in Term Newborns.

Am J Perinatol 2022 Jan 13. Epub 2022 Jan 13.

Biochemistry, Gaziantep University, Gaziantep, Turkey.

Objective As newborns are exposed to oxidative stress during delivery, cord clamping techniques play significant role on antioxidant status. In this study, we aimed to show the relationship between early cord clamping (ECC), delayed cord clamping (DCC) and cut umblical cord milking (C-UCM) techniques with total oxidant capacity (TOC), total antioxidant capacity (TAC) and peroxynitrite levels. Study Design Sixty-nine term infants were selected with APGAR score of 7 and above in the first and fifth minutes. Read More

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January 2022

Limonene, a citrus monoterpene, non-complexed and complexed with hydroxypropyl-β-cyclodextrin attenuates acute and chronic orofacial nociception in rodents: Evidence for involvement of the PKA and PKC pathway.

Phytomedicine 2021 Dec 18;96:153893. Epub 2021 Dec 18.

Department of Physiology, Laboratory of Neuroscience and Pharmacological Assays (LANEF), Federal University of Sergipe, São Cristóvão, SE, Brazil; Health Sciences Graduate Program (PPGCS), Federal University of Sergipe, Aracaju, SE, Brazil.

Background: Chronic orofacial pain is a serious public health problem with a prevalence of 7-11% in the population. This disorder has different etiologies and characteristics that make pharmacological treatment difficult. Natural products have been shown to be a promising source of treatments for the management of chronic pain, as an example the terpenes. Read More

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December 2021

Ulk1-dependent alternative mitophagy plays a protective role during pressure overload in the heart.

Cardiovasc Res 2022 Jan 9. Epub 2022 Jan 9.

Department of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, USA.

Aims: Well-controlled mitochondrial homeostasis, including a mitochondria-specific form of autophagy (hereafter referred to as mitophagy), is essential for maintaining cardiac function. The molecular mechanism mediating mitophagy during PO is poorly understood. We have shown previously that mitophagy in the heart is mediated primarily by Atg5/Atg7-independent mechanisms, including Unc-51-like kinase1 (Ulk1)-dependent alternative mitophagy, during myocardial ischemia. Read More

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January 2022

A Quality Improvement Project to Delay Umbilical Cord Clamping Time.

Pediatr Qual Saf 2021 Sep-Oct;6(5):e452. Epub 2021 Sep 24.

Department of Pediatrics, Joan C Edwards School of Medicine, Marshall University, Huntington, W.Va.

Delayed cord clamping (DCC) has numerous benefits to the neonate, including increased hemoglobin levels, decreased need for red blood cell transfusions, and decreased incidence of necrotizing enterocolitis and intraventricular hemorrhage. A preliminary observational study at our institution demonstrated 12% of the observed deliveries met the DCC standard, defined as umbilical cord clamping at least 30-60 seconds after birth. Therefore, we designed a quality improvement project to increase the percentage of deliveries using DCC. Read More

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September 2021

Biomechanical and morphological evaluation of aortic wall changes related to the cross-clamping method in different surgical techniques.

J Vasc Bras 2021 1;20:e20200204. Epub 2021 Dec 1.

Universidade Federal de São Paulo - UNIFESP, Escola Paulista de Medicina, São Paulo, SP, Brasil.

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December 2021

Surgical outcomes of total arch replacement with modified elephant trunk technique in type A aortic dissection: insights from single-center experience.

Asian Cardiovasc Thorac Ann 2022 Jan 11:2184923211070115. Epub 2022 Jan 11.

Department of Thoracic and Cardiovascular Surgery, 385685Nanjing First Hospital, 385685Nanjing Medical University, P.R. China.

Background: Total arch replacement with modified elephant trunk technique plays an important role in treating acute type A aortic dissection in China. We aim to summarize the therapeutic effects of this procedure in our center over a 17-year period.

Methods: Consecutive patients treated at our hospital due to type A aortic dissection from January 2004 to January 2021 were studied. Read More

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January 2022

Metoclopramide and Propofol to Prevent Nausea and Vomiting during Cesarean Section under Spinal Anesthesia: A Randomized, Placebo-Controlled, Double-Blind Trial.

J Clin Med 2021 Dec 26;11(1). Epub 2021 Dec 26.

Department of Emergency, SS.ma Annunziata University Hospital, Via dei Vestini, 66100 Chieti, Italy.

Background: Intra-operative nausea, vomiting and retching (NVR) are frequently associated with subarachnoid anesthesia (SA) in women undergoing cesarean section (CS). In this study performed in women undergoing CS under SA with a risk factor control strategy, we compared saline (placebo), propofol, metoclopramide and both drugs to prevent NVR.

Methods: We recorded NVR events in 110 women undergoing CS who were randomized after umbilical cord clamping to receive saline (S; = 27), metoclopramide 10 mg (M; = 28), propofol 1 mg/kg/h (P; = 27) or both drugs (PM; = 28). Read More

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December 2021

Lead Dependent Tricuspid Valve Dysfunction-Risk Factors, Improvement after Transvenous Lead Extraction and Long-Term Prognosis.

J Clin Med 2021 Dec 24;11(1). Epub 2021 Dec 24.

Department of Cardiac Surgery, Masovian Specialistic Hospital of Radom, 26-617 Radom, Poland.

Background: Lead-related tricuspid valve dysfunction (LDTVD) has not been studied in a large population and its management remains controversial.

Methods: An analysis of the clinical data of 2678 patients undergoing transvenous lead extraction (TLE) in years 2008-2021 was conducted, with a separate group of 119 patients with LDTVD. Potential risk factors for LDTVD, improvement in valve function, and long-term prognosis after TLE were assessed. Read More

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December 2021

Long-Term Follow-Up of Device-Assisted Clampless Off-Pump Coronary Artery Bypass Grafting Compared with Conventional On-Pump Technique.

Int J Environ Res Public Health 2021 Dec 27;19(1). Epub 2021 Dec 27.

Division of Cardiac Surgery, Tor Vergata University Hospital, Viale Oxford 81, 00133 Rome, Italy.

Study Objective: To evaluate the long-term outcomes of clampless off-pump coronary artery bypass grafting (C-OPCAB) compared with conventional on-pump double clamping coronary artery bypass grafting (C-CABG).

Methods: From October 2006 to December 2011, 366 patients underwent isolated coronary artery bypass grafting. After propensity score matching of preoperative variables, 143 pairs were selected who received C-OPCAB with the use of device-assisted PAS-Port proximal venous graft anastomoses or C-CABG, performed by the same surgeon experienced in both techniques. Read More

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December 2021

Characterization of a Geopolymer Foam by X-ray Tomography.

Front Chem 2021 24;9:754355. Epub 2021 Dec 24.

CEA, DES, ISEC, DE2D, SEAD, LCBC, Université of Montpellier, Marcoule, France.

Metakaolin based geopolymer foams were synthesized at room temperature by direct foaming using hydrogen peroxide (HO) as a blowing agent and two types of surfactants such as AER5 and CTAB allowing to tune the connection between two adjacent cells. In the field of decontamination process of liquid wastes, the knowledge of the topology of the generated macroporous network is a primary of interest. Due to the complex structure of porous material, 2D conventional techniques as optical or scanning electron microscopy are often not able to provide all the necessary informations. Read More

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December 2021

Urinary TIMP-2 and IGFBP-7 protein levels as early predictors of acute kidney injury after cardiac surgery.

J Card Surg 2022 Jan 9. Epub 2022 Jan 9.

Department of Cardiothoracic Surgery, University Hospital of Giessen and Marburg, Marburg, Germany.

Background: Acute kidney injury (AKI) is a frequent complication associated with on-pump cardiac surgery. Early recognition may alter their prognosis. Therefore, the urinary concentrations of TIMP-2 (tissue inhibitor of metalloproteinases-2) and IGFBP7 (insulin-like growth factor-binding protein) as predictors for AKI were studied. Read More

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January 2022

Simultaneous robotic partial nephrectomy for bilateral renal masses.

World J Urol 2022 Jan 9. Epub 2022 Jan 9.

Department of Urology, Careggi University Hospital, Florence, Italy.

Purpose: There is currently no consensus regarding the optimal treatment strategy for patients presenting with synchronous bilateral renal masses. The decision to perform bilateral procedures on the same intervention or in staged procedures is debated. The aim of this manuscript is to analyse the outcomes of simultaneous robot-assisted partial nephrectomy (RAPN) in a series of patients with bilateral renal masses treated at five Italian robotic institutions. Read More

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January 2022

LncRNA H19 modulates neuropathic pain through miR-141/GLI2 axis in chronic constriction injury (CCI) rats.

Transpl Immunol 2022 Jan 6;71:101526. Epub 2022 Jan 6.

Department of Anesthesiology, Shaoxing Central Hospital, No.1 Huayu Road, Shaoxing City, Zhejiang Province 313030, China. Electronic address:

Background: The participation of long non-coding RNAs (lncRNAs) in progressions of chronic pain has been evaluated. We explored mechanisms of lncRNA H19 in chronic constriction injury (CCI)-induced neuropathic pain model in vivo.

Methods: The expressions of lncRNA H19, microRNA-141, and GLI Family Zinc Finger 2 (GLI2) in CCI rats were determined by using RT-qPCR. Read More

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January 2022

Dendritic Excitability and Synaptic Plasticity In Vitro and In Vivo.

Neuroscience 2022 Jan 5. Epub 2022 Jan 5.

Department of Neuroscience, Columbia University, New York, NY, USA; Mortimer B. Zuckerman Mind Brain Behavior Institute, New York, NY, USA. Electronic address:

Much of our understanding of dendritic and synaptic physiology comes from in vitro experimentation, where the afforded mechanical stability and convenience of applying drugs allowed patch-clamping based recording techniques to investigate ion channel distributions, their gating kinetics, and to uncover dendritic integrative and synaptic plasticity rules. However, with current efforts to study these questions in vivo, there is a great need to translate existing knowledge between in vitro and in vivo experimental conditions. In this review, we identify discrepancies between in vitro and in vivo ionic composition of extracellular media and discuss how changes in ionic composition alter dendritic excitability and plasticity induction. Read More

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January 2022

Robotic Left Hepatectomy Extended to Caudate Lobe and Common Biliary Duct for Hilar Cholangiocarcinoma.

Ann Surg Oncol 2022 Jan 7. Epub 2022 Jan 7.

Department of Digestive Surgery, Hôpital Européen, Marseille, France.

Background: The safety and efficiency of minimally invasive approaches for liver resection have been confirmed (Wakabayashi in Ann Surg, 2015). However, laparoscopy suffers from several limitations due to technical difficulties, particularly for difficult hepatectomy with lymphadenectomy, biliary, and vascular reconstruction. Robotic assets could improve accessibility for difficult liver resections (Liu in World J Gastroenterol 25: 1432-1444), (Chou in Zhonghua Wai Ke Za Zhi 58: 230-234, 2020). Read More

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January 2022

Laparoscopic Segmentectomy IV Using Hepatic Round Ligament Approach Combined with Fluorescent Negative Staining Method.

Ann Surg Oncol 2022 Jan 7. Epub 2022 Jan 7.

Department of Liver Surgery, Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China.

Background: Laparoscopic segmentectomy, which maximizes the preservation of the functional hepatic reserve and the possibility for future repeat hepatectomy while ensuring adequate surgical margin, is a feasible alternative to hemihepatectomy for hepatocellular carcinoma (HCC) (Vigano et al. in Ann Surg 270(5):842-851, 2019, Ishizawa et al. in Ann Surg 256(6):959-964, 2012). Read More

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January 2022

[Analysis of animal models of hypertension based on characteristics of clinical symptoms of Chinese and western medicine].

Zhongguo Zhong Yao Za Zhi 2021 Dec;46(24):6574-6578

Hunan University of Chinese Medicine Changsha 410208, China.

Hypertension, a cardiovascular disease with main clinical manifestations of dizziness and elevated blood pressure, especially elevated arterial pressure, features high prevalence rate and low control rate, which affects patients' quality of life. Therefore, establishing a good animal model of hypertension is of great significance for its diagnosis and clinical prevention and treatment. Based on the clinical characteristics of hypertension in traditional Chinese and western medicine, this study summarized the advantages and disadvantages of current hypertension animal models: gene-related model, surgery-caused model, drug-induced model, and environment-induced model, and investigated the similarity to the clinical symptoms in traditional Chinese medicine and Western medicine. Read More

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December 2021

Open chest selective aortic arch perfusion vs open cardiac massage as a means of perfusion during in exsanguination cardiac arrest: a comparison of coronary hemodynamics in swine.

Eur J Trauma Emerg Surg 2022 Jan 4. Epub 2022 Jan 4.

Adams Cowley Shock Trauma Center, University of Maryland Medical System, 22 S. Greene Street, Baltimore, MD, 21201, USA.

Aim: To describe and compare the aortic-right atrial pressure (AoP-RAP) gradients and mean coronary perfusion pressures (CPPs) generated during open chest selective aortic arch perfusion (OCSAAP) with those generated during open cardiac massage (OCM) in hypovolemic swine.

Methods: Ten male Hanford swine utilized in a prior poly-trauma study were included in the study. Animals were rendered hypovolemic via a 30% volume bleed. Read More

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January 2022

Effect of Stent Placement on Survival in Patients with Malignant Portal Vein Stenosis: A Propensity Score-Matched Study.

Korean J Radiol 2022 01;23(1):68-76

Institute of Biomedical Science, Catholic Kwandong University International St. Mary's Hospital, Incheon, Korea.

Objective: Percutaneous portal vein (PV) stent placement can be an effective treatment for symptoms associated with portal hypertension. This study aimed to evaluate the effect of PV stenting on the overall survival (OS) in patients with malignant PV stenosis.

Materials And Methods: Two groups of patients with malignant PV stenosis were compared in this retrospective study involving two institutions. Read More

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January 2022

[Clinical Value of Ultrasound in Evaluating Stent Placement for Managing Graft Stenosis after Meso-rex Bypass].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2021 Dec;43(6):886-891

Department of Ultrasound, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine,Tsinghua University,Beijing 102218,China.

Objective To explore the feasibility of using ultrasound to evaluate stent placement for managing graft stenosis after Meso-rex bypass for cavernous transformation of the portal vein in adults. Methods This study enrolled the patients who underwent Meso-rex bypass due to cavernous transformation of the portal vein,were diagnosed graft stenosis by postoperative ultrasound,and then underwent percutaneous portal vein puncture portography and stent placement.We then compared the ultrasonic measurement indicators and sonographic manifestations before and after stent placement,and evaluated the alleviation of portal hypertension symptoms after stent placement and related clinical indexes. Read More

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December 2021

Activation of the aryl hydrocarbon receptor by clozapine induces preadipocyte differentiation and contributes to endothelial dysfunction.

J Psychopharmacol 2022 Jan 3:2698811211055811. Epub 2022 Jan 3.

Neurobiochemical Research Unit, Department of Psychiatry, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Background: The superior therapeutic benefit of clozapine is often associated with metabolic disruptions as obesity, insulin resistance, tachycardia, higher blood pressure, and even hypertension.

Aims: These adverse vascular/ metabolic events under clozapine are similar to those caused by polycyclic aromatic hydrocarbons (PAHs), and clozapine shows structural similarity to well-known ligands of the aryl hydrocarbon receptor (AhR). Therefore, we speculated that the side effects caused by clozapine might rely on AhR signaling. Read More

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January 2022

The Relationship between Patterns of Remodeling and Degree of Enhancement in Patients with Atherosclerotic Middle Cerebral Artery Stenosis: A High-Resolution MRI Study.

Neurol India 2021 Nov-Dec;69(6):1663-1669

Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.

Purpose: The aim of this research was to investigate the relationship between remodeling patterns and degree of enhancement in patients with atherosclerotic middle cerebral artery (MCA) stenosis using high-resolution magnetic resonance imaging (HR-MRI).

Materials And Methods: From August 2015 to May 2016, 38 consecutive patients with unilateral MCA stenosis on time-of-flight (TOF) MR angiography were prospectively enrolled. The routine MR scan and cross-sectional images of the stenotic MCA vessel wall on HR-MRI were performed in all patients. Read More

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January 2022

Parathyroid hormone promotes maxillary expansion and reduces relapse in the repeated activation maxillary expansion rat model by regulating Wnt/β-catenin pathway.

Prog Orthod 2022 Jan 3;23(1). Epub 2022 Jan 3.

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, #14, 3rd Section, South Renmin Road, Chengdu, 610041, People's Republic of China.

Background: Constricted maxillary bone is a common skeletal deformity, which may lead to crowding and posterior crossbite. Mid-palatal suture expansion is often used to increase the maxillary width, but its skeletal effects are limited and tend to relapse, even with prolonged retention. We hypothesized that parathyroid hormone (PTH) may reduce the relapse of maxillary expansion. Read More

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January 2022

Hydrodynamic cavitation efficiently inactivates potato virus Y in water.

Ultrason Sonochem 2021 Dec 28;82:105898. Epub 2021 Dec 28.

Department of Biotechnology and Systems Biology, National Institute of Biology, Večna pot 111, 1000 Ljubljana, Slovenia.

Waterborne plant viruses can destroy entire crops, leading not only to high financial losses but also to food shortages. Potato virus Y (PVY) is the most important potato viral pathogen that can also affect other valuable crops. Recently, it has been confirmed that this virus is capable of infecting host plants via water, emphasizing the relevance of using proper strategies to treat recycled water in order to prevent the spread of the infectious agents. Read More

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December 2021

The effect of adenotonsillectomy and rapid maxillary expansion on the upper airway in pediatric obstructive sleep apnea: a randomized crossover-controlled trial.

Sleep 2021 Dec 31. Epub 2021 Dec 31.

Professor, Departament of Pediatric Dentistry and Orthodontics, Federal University of Uberlândia, Uberlândia, Brazil.

Study Objectives: We aimed to determine the effects of adenotonsillectomy (AT) and rapid maxillary expansion (RME) on the apnea-hypopnea index (AHI) and compare volumetric changes in the upper airway (UA) arising from AT and RME.

Methods: Thirty-nine children who presented with maxillary constriction and grade III/IV tonsillar hypertrophy were randomized into two groups. One group underwent AT as the first treatment, and the other group underwent RME. Read More

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December 2021

Effects of cyanocobalamin and its combination with morphine on neuropathic rats and the relationship between these effects and thrombospondin-4 expression.

Korean J Pain 2022 Jan;35(1):66-77

Department of Medical Pharmacology, Faculty of Medicine, Ege University, Bornova, Izmir, Turkey.

Background: Thrombospondin-4 (TSP4) upregulates in the spinal cord following peripheral nerve injury and contributes to the development of neuropathic pain (NP). We investigated the effects of cyanocobalamin alone or in combination with morphine on pain and the relationship between these effects and spinal TSP4 expression in neuropathic rats.

Methods: NP was induced by chronic constriction injury (CCI) of the sciatic nerve. Read More

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January 2022

Obstructive sleep apnoea in pycnodysostosis: A three-dimensional upper airway analysis.

Orthod Craniofac Res 2021 Dec 28. Epub 2021 Dec 28.

Section of Orthodontics, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark.

Aim: To assess the upper airway (UA) morphology in patients with pycnodysostosis with a 3D analysis, compare results with normative data and investigate the correlation of the total volume (TV) with other UA morphology variables.

Materials And Methods: Cone beam computed tomography (CBCT) images of eight Danish patients with pycnodysostosis (4 males and 4 females with a mean age of 31.8 years, SD: 16. Read More

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December 2021

Perceval Sutureless Bioprosthesis for Degenerative Aortic Valve Stenosis: Initial Experience With 67 Patients.

Heart Surg Forum 2021 Dec 28;24(6):E1065-E1069. Epub 2021 Dec 28.

Clinic for cardiac surgery Clinical Center of Serbia.

Objective: The objective of this prospective study was to evaluate the characteristics (positive and negative) of Perceval S valve in patients undergoing aortic valve replacement with a biological prosthesis. The study included 67 patients operated on at our institution and a mean follow-up period of 18 months.

Methods: From June 2016 to November 2019, 209 patients underwent aortic valve replacement with a biological prosthesis. Read More

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December 2021

CT Angiography Manual Multiplanar Vessel Diameter Measurement vs. Semiautomated Perpendicular Area Minimal Caliber Computation of Internal Carotid Artery Stenosis.

Front Cardiovasc Med 2021 9;8:740237. Epub 2021 Dec 9.

Institute of Diagnostic and Interventional Neuroradiology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.

To determine the diagnostic agreement of CT angiography (CTA) manual multiplanar reformatting (MPR) stenosis diameter measurement and semiautomated perpendicular stenosis area minimal caliber computation of extracranial internal carotid artery (ICA) stenosis. We analyzed acute cerebral ischemia CTA at our tertiary stroke center in a 12-month period. Prospective NASCET-type stenosis grading for each ICA was independently performed using (1) MPR to manually determine diameters and (2) perpendicular stenosis area with minimal caliber semiautomated computation to grade luminal constriction. Read More

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December 2021