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Clin Exp Dermatol 2021 Apr 16. Epub 2021 Apr 16.

Department of Dermatology, Circle Hospital, Bath, UK.

Sudocrem Antiseptic Healing Cream® is a popular barrier cream in the UK and Ireland. It contains the allergens benzyl alcohol, benzyl benzoate, benzyl cinnamate, sodium benzoate (benzoic acid), linalyl acetate, lavender, lanolin, beeswax, butylated hydroxyanisole, sorbitan sesquioleate, and propylene glycol; and excipients zinc oxide, liquid paraffin, paraffin wax, microcrystalline wax, and citric acid. Read More

New Phytol 1997 Jul;136(3):425-432

Institut für Ökologie der Pflanzen, Westfälische Wilhelms-Universität Münster, D-48143 Münster, Germany.

Changes in leaf water content, night-time accumulation of malic (δ-malate) and citric acid (δ-citrate) and phosphoenolpyruvate carboxylase (PEPC, EC 4.1.1. Read More

J Med Food 2021 Apr;24(4):348-357

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Chronic cough is very common in respiratory clinics, and no effective drugs are available. (Turcz.) Baill. Read More

Mol Cell Oncol 2021 1;8(2):1859917. Epub 2021 Feb 1.

Department of Cancer Biology, University of Cincinnati, Cincinnati, OH, USA.

Tobacco smoking (TS) results in reprogramming of major metabolic pathways, including glycolysis, the citric acid (TCA) cycle, oxidative phosphorylation, and metabolism of aspartate, glutamate and glutamine in clear cell renal cell carcinoma (ccRCC). TS alters the distribution and activities of cadmium, arsenic and copper in a manner mechanistically supporting metabolic remodeling. Alterations in metabolism and metal distribution identify new actionable targets for treatment of ccRCC. Read More

Int J Food Sci Nutr 2021 Apr 15:1-13. Epub 2021 Apr 15.

Department of Consumer and Food Sciences and Institute for Food, Nutrition and Well-being, University of Pretoria, Pretoria, South Africa.

Food-to-food fortification (FtFF) with moringa leaf (iron source) and/or baobab fruit (citric acid and ascorbic acid source) (each 13-15 g/100 g porridge dry basis (db)) was studied to improve iron and zinc nutritive quality in African-type wholegrain maize-based porridges using dialysability assay. Moringa FtFF decreased percentage and total bioaccessible iron and zinc, by up to 84% and 45%, respectively. Moringa was very high in calcium, approximately 3% db and calcium-iron-phytate complexes inhibit iron bioavailability. Read More

Nan Fang Yi Ke Da Xue Xue Bao 2021 Mar;41(3):358-369

School of Pharmacy, Minzu University of China, Key Laboratory of Ethnomedicine, Ministry of Education, Beijing 100081, China.

Objective: To analyze the species, abundance and structure differences of intestinal flora between patients with type 2 diabetes mellitus (T2D) and healthy individuals and explore the correlation between intestinal flora changes and T2D.

Objective: We collected a total of 133 clinical fecal samples from 78 healthy individuals and 55 patients with T2D. Hiseq2500 was used for high-throughput sequencing of the V3+V4 regions of the 16S rRNA gene. Read More

J Chromatogr A 2021 Mar 25;1645:462075. Epub 2021 Mar 25.

Department of Food Preservation, University of Chemistry and Technology Prague, Technická 3, 166 28 Prague 6, Czech Republic.

An electrophoretic method (on-line coupled capillary isotachophoresis and capillary zone electrophoresis) with conductometric detection for the determination of free taurine in selected food and feed is described. Taurine is converted to isethionic acid by van Slyke method. Under optimized conditions (leading electrolyte: 5 mM HCl, 10 mM glycylglycine, and 0. Read More

Int J Biol Macromol 2021 Apr 14;182:554-563. Epub 2021 Apr 14.

Food Engineering and Packaging Division, Defence Food Research Laboratory, Mysore 570011, India.

Starch from talipot palm trunk (Corypha umbraculifera L.), a new starch source, was treated with different citric acid concentrations (5%, 10%, 20%, and 40% of the dry weight of starch) to produce citrate starch. The influence of citric acid treatment on physicochemical, pasting, structural, thermal, rheological, and digestibility properties of talipot palm starch were studied. Read More

J Chem Inf Model 2021 Apr 13. Epub 2021 Apr 13.

Department of Medical Physics and Biomedical Engineering, UCL, London WC1E 6BT, U.K.

Single amino acid substitutions within protein structures often manifest with clinical conditions in humans. The mutation of a single amino can significantly alter protein folding and stability, or change protein dynamics to influence function. The chemical engineering field has developed a large toolset for predicting the influence of point mutations with the aim of guiding the design of improved and more stable proteins. Read More

Food Chem 2021 Mar 29;356:129723. Epub 2021 Mar 29.

Federal Institute of Education, Science and Technology of Amazonas, Manaus, Amazonas, Brazil. Electronic address:

Theobroma speciosum, known as "cacauí" in Brazil, is considered a prominent unconventional food plant. The objective of this work was to evaluate the chemical profiles, antioxidant capacity and minerals of the aqueous extract and fractions from its flowers. The identified compounds were sugars, organic acids and phenolics compounds such as citric, malic and protocatechuic acids, quercetin, quercetin pentoside and quercetin-3-O-glucoside. Read More

J Food Sci 2021 Apr 12. Epub 2021 Apr 12.

Facultad de Ciencias Químicas, Universidad Autónoma de San Luis Potosí, Av. Dr. Manuel Nava No 6 Zona Universitaria, San Luis Potosí, San Luis Potosí, México.

Specific heat capacity ( ) is regarded as a fundamental parameter for the design, operation, and optimization of the heat transfer equipment widely used in the food industry. Using the calorimetric ASTM E1269-11 standard procedure, the -temperature ( ) curves of fruit juice model systems prepared at different mass fractions of fructose/glucose/sucrose/citric acid/pectin and water were measured. Thus, experimental data of for solid samples in crystalline and amorphous states from -80 °C up to the melting temperature range and for aqueous samples from -80 to 110 °C were generated. Read More

ACS Omega 2021 Apr 22;6(13):9001-9012. Epub 2021 Mar 22.

Department of Petroleum Engineering, Shahid Bahonar University of Kerman, Kerman 76169-13439, Iran.

Reservoir conformance control methods may significantly improve enhanced oil recovery technologies through reduced water production and profile correction. Excessive water production in oil and gas reservoirs leads to severe problems. Water shutoff and conformance control are, therefore, financially and environmentally advantageous for the petroleum industry. Read More

ACS Omega 2021 Apr 24;6(13):8884-8893. Epub 2021 Mar 24.

CNR-STIIMA, Italian National Research Council-Institute of Intelligent Industrial Technologies and Systems for Advanced Manufacturing, C.so G. Pella 16, 13900 Biella, Italy.

Interest in insects as waste biomass bioconverters and their use as valuable resources for fat, proteins, and chitin has increased considerably in the last few years. In this study, proteins were extracted from defatted black soldier fly (BSF) () exuviae by green hydrolysis using superheated water at 150 °C for 20 h, and the remaining chitin was deacetylated into chitosan and used as a finishing agent for polyester fabrics. A total amount of 7% fat, 40% proteins, and 20% chitin was obtained from BSF exuviae. Read More

Virusdisease 2021 Apr 5:1-12. Epub 2021 Apr 5.

Department of Computer Science, Jamia Millia Islamia, New Delhi, 110025 India.

The novel coronavirus (2019-nCoV) has led to the apex pandemic in 2020, responsible for the recent sequential spread. The 2019-nCoV has been discerned to be a Beta-BAT-SARS-CoV-2 lineage. The gene ontology (GO) identifies the virus to be localized in the Golgi apparatus with a vital molecular function of and viral progression. Read More

Talanta 2021 Jul 12;229:122298. Epub 2021 Mar 12.

INQUISUR, Departamento de Química, Universidad Nacional Del Sur (UNS)-CONICET, Av. Alem 1253, 8000, Bahía Blanca, Argentina. Electronic address:

A new portable and simple 3D printed device was designed for free chlorine determination in water samples. The analytical method was based on the quenching caused by free chlorine on the fluorescence emission of the carbon dots (CD) synthesized from citric acid and urea. The fluorescence was captured through the camera of a smartphone, which was coupled to the 3D printed device, and the images were processed using the RGB system by the ImageJ 1. Read More

BMC Genomics 2021 Apr 10;22(1):255. Epub 2021 Apr 10.

College of Animal Science, Guizhou university, Guiyang, 550025, Guizhou, China.

Background: Lysine succinylation is a naturally occurring post-translational modification (PTM) that is ubiquitous in organisms. Lysine succinylation plays important roles in regulating protein structure and function as well as cellular metabolism. Global lysine succinylation at the proteomic level has been identified in a variety of species; however, limited information on lysine succinylation in plant species, especially paper mulberry, is available. Read More

Biomed Res Int 2021 24;2021:5544196. Epub 2021 Mar 24.

Physical Sciences in Relation to Dentistry, Institute of Dentistry, Dental Physical Sciences Unit, Queen Mary University of London, London, UK.

Objectives: The aim of this study was to evaluate the protective effect of using four different fluoride bioactive enamel sealers against an acidic erosion challenge.

Materials And Methods: A sample of 50 freshly extracted sound upper premolars had their buccal surface bonded to 50 orthodontic brackets using Transbond PLUS color change adhesive; the first four groups had four compositions of fluoride bioactive glasses based on 37 mol% SiO, 43.9-53. Read More

Ann Palliat Med 2021 Mar 24. Epub 2021 Mar 24.

Department of Urology, China Academy of Chinese medical Sciences Guanganmen Hospital, Beijing, China.

Background: This study aims to explore the mechanism of the Huayu Jianpi Fangshi decoction in urolithiasis prevention.

Methods: The present study was designed as a randomized, double-blinded, placebo-controlled clinical trial. Sixty patients with the qi stagnation and blood stasis, spleen deficiency, and dampness obstruction types of urolithiasis were randomly divided into two groups: the treatment group and the control group (n=30 in both groups). Read More

J Fish Dis 2021 Apr 8. Epub 2021 Apr 8.

Jiangsu Key Laboratory of Zoonosis/Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Jiangsu, China.

Pathogens adapted to sub-lethal acidic conditions could increase the virulence and survival ability under lethal conditions. In the aquaculture industry, feed acidifiers have been used to increase the growth of aquatic animals. However, there is limited study on the effects of acidic condition on the virulence and survival of pathogens in aquaculture. Read More

J Pharm Bioallied Sci 2020 Nov 5;12(Suppl 2):S743-S746. Epub 2020 Nov 5.

Department of Pharmacy, Universitas Syiah Kuala, Aceh, Indonesia.

Introduction: Robusta coffee () is one of the many crops cultivated in Aceh, and at present is only being used as a drink. Research has shown the potential of many pharmacological uses for coffee, including its use as a remedy to treat diabetes. Effervescent granules are one of the oral dosage forms that can not only mask the unpleasant taste of bioactive substances, but also have a high aesthetic value and can contain relatively large doses of bioactive substances. Read More

Cryobiology 2021 Apr 4. Epub 2021 Apr 4.

Platform for AI and ET, University of Veterinary Medicine Vienna, Veterinärplatz 1, Vienna, Austria. Electronic address:

We compared the results of using egg yolk plasma (EYP) instead of egg yolk (EY) in a TRIS-based Equex STM Paste freezing extender system for dog semen [25]. We also tested whether the addition of lecithin and catalase to the EYP extenders would improve results. Fractionated semen collection was done in 17 stud dogs and the sperm rich fraction diluted with different extenders in 2 steps: (I) TRIS-fructose-citric acid extender (TRIS) containing 20% egg yolk (EY) and 3% glycerol [25], (II) TRIS containing 20% egg yolk plasma (EYP) and 3% glycerol, and (III) TRIS containing 20% EYP and 0. Read More

ACS Nano 2021 Apr 7. Epub 2021 Apr 7.

School of Physics, University of New South Wales, Sydney, New South Wales 2052, Australia.

We report on the postgrowth shaping of free-standing two-dimensional (2D) InAs nanofins that are grown by selective-area epitaxy and mechanically transferred to a separate substrate for device fabrication. We use a citric acid-based wet etch that enables complex shapes, for example, van der Pauw cloverleaf structures, with patterning resolution down to 150 nm as well as partial thinning of the nanofin to improve local gate response. We exploit the high sensitivity of the cloverleaf structures to transport anisotropy to address the fundamental question of whether there is a measurable transport anisotropy arising from wurtzite/zincblende polytypism in 2D InAs nanostructures. Read More

Ecotoxicol Environ Saf 2021 Apr 3;216:112156. Epub 2021 Apr 3.

Department of Biology, Wilfrid Laurier University, Waterloo, ON, Canada. Electronic address:

The potential for Ni toxicity in seawater is of concern because of mining and processing activities in coastal regions. Determining Ni speciation is vital to understanding and predicting Ni toxicity and for bioavailability-based nickel risk assessment. The goal of this study was to characterize the complexation of Ni in relation to toxicity using embryological development of purple sea urchin (S. Read More

Plant Dis 2021 Apr 6. Epub 2021 Apr 6.

University of California, Plant Pathgology, Riverside, Riverside, California, United States, 92521;

Natamycin is a new postharvest biofungicide for citrus and some other fruit crops in the United States that can be effectively used in recycling drench or flooder treatments. These types of applications necessitate sanitation of the fungicide solution to ensure that it remains free from contamination by bacteria that potentially are human pathogens. In in vitro experiments, heated (48°C) citric acid (1,100 μg/ml or 2,200 μg/ml) amended with sodium dodecylbenzensulfonate (SDBS; 55 μg/ml or 110 μg/ml, respectively) significantly reduced viability of E. Read More

Eur J Pharm Biopharm 2021 Apr 2. Epub 2021 Apr 2.

College of Pharmaceutical Sciences, Key Laboratory of Pharmaceutical Quality Control of Hebei Province, Institute of Life Science and Green Development, Hebei University, Baoding 071002, China. Electronic address:

The aim of this study was to formulate osmotic pump capsules (OPCs) to control the release of nifedipine (NP). NP solid dispersion was prepared by solvent evaporation method. The prepared mixture of NP solid dispersion and various excipients were filled into the commercial HPMC hard capsule shells and then coated with cellulose acetate (CA) solution to form NP-OPC. Read More

Curr Med Res Opin 2021 Apr 5:1-10. Epub 2021 Apr 5.

Medical Department, UPSA S.A.S, Rueil Malmaison, France.

Objective: Paracetamol has an established place in the management of mild-to-moderate pain, but has certain limitations, including varying bioavailability, and potential hepatotoxicity if taken in overdose. Effervescent formulations may help to overcome these limitations.

Methods: Pubmed searches, with no limits on date or language, were conducted in February 2020. Read More

ACS Omega 2021 Mar 15;6(12):8119-8130. Epub 2021 Mar 15.

School of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan 430070, China.

The narrow pH range of Fenton oxidation restricts its applicability in water pollution treatment. In this work, a CDs/g-CN/Cu O composite was synthesized via a stepwise thermal polymerization method using melamine, citric acid, and CuO. Adding HO to form a heterogeneous Fenton system can degrade Rhodamine B (Rh B) under dark conditions. Read More

Langmuir 2021 Apr 5;37(14):4137-4146. Epub 2021 Apr 5.

Key Laboratory of Superlight Material and Surface Technology of Ministry of Education, College of Material Science and Chemical Engineering, Harbin Engineering University, 150001 Harbin, China.

Hydroxyapatite (HA) is the main inorganic component of human bones and teeth. It has good biocompatibility and bioactivity, which promotes its good application prospects in the field of bone drug carriers. In this study, tetraethylenepentamine-graphene (rGO-TEPA)/CaCO:HA composite microspheres were prepared microwave hydrothermal synthesis using rGO-TEPA/CaCO solid microspheres as intermediates. Read More

J Mech Behav Biomed Mater 2021 Mar 29;119:104496. Epub 2021 Mar 29.

Department of Mechanical Engineering, Faculty of Engineering, Iğdır University, 76000, Iğdır, Turkey; Department of Mechanical Engineering, Faculty of Engineering, Atatürk University, 25240, Erzurum, Turkey.

In line with the increase in orthopedic prosthetic surgeries, there has been a significant rise in periprosthetic joint infections (PJI) due to Methicillin-Resistant Staphylococcus Aureus (MRSA) bacteria. In case of infection, antibiotic-added spacers are temporarily placed into the periprosthetic region. With the release of antibiotics usually failing to work in fighting off infection, recent studies have centered around developing more effective approaches. Read More

J Sci Food Agric 2021 Apr 2. Epub 2021 Apr 2.

School of Food Science and Biotechnology, Zhejiang Gongshang University, Zhejiang, 310018, China.

Background: our taste perception builds on both chemical and physiological foundations, plays an important role in food flavor, including fruit, beer, wine and beverage. A reliable and unified sourness standard and sourness conversion method for researchers and food enterprises are necessary to obtain comparable conclusions and attractive food goods.

Results: This study established an optimized organic acids sensory sourness analysis and sourness conversion method based on the sour sensory difference strength curves, which consisted of the absolute threshold value and sensory difference threshold values. Read More