166 results match your criteria chylothorax edema

Recognition and Management of Acute and Late Complications of Pneumonectomy: Clinical Cases and Treatment.

Thorac Surg Clin 2021 Aug;31(3):293-302

Department of Surgery, Section of Thoracic Surgery, University of Calgary, Foothills Medical Centre, Room G33H, 1403 29th Street Northwest, Calgary, Alberta T2N 2T9, Canada.

Several important complications of pneumonectomy are discussed in a case-based format. Topics include chylothorax, cardiac herniation, postpneumonectomy syndrome, postpneumonectomy pulmonary edema, bronchopleural fistula, and empyema. Read More

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Recurrent Chylous Ascites Leading to Transudative Chylothorax Due to Bi-Ventricular Heart Failure.

J Investig Med High Impact Case Rep 2021 Jan-Dec;9:23247096211026144

Appalachian Regional Healthcare, Internal Medicine Residency Program, Harlan, KY, USA.

Chylothorax is a pleural effusion of >110 mg/dL of triglycerides with a milky appearance with transudative being rare. In this article, we present a case of transudative chylothorax with concurrent chylous ascites that is secondary to congestive heart failure (CHF). A 70-year-old male with CHF with ejection fraction of 10%, coronary artery disease status post coronary artery bypass graft, sleep apnea, chronic kidney disease stage 3, and chronic obstructive pulmonary disease presented with worsening abdominal distention, shortness of breath, and increased lower extremities edema. Read More

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Non-immune hydrops fetalis secondary to congenital chylothorax with diffuse interstitial lung disease: a diagnostic conundrum.

BMJ Case Rep 2021 Apr 16;14(4). Epub 2021 Apr 16.

Department of Neonatal and Developmental Medicine, Singapore General Hospital, Singapore.

A Chinese male infant was born at 35 weeks weighing 2935 g to a mother with polyhydramnios and prenatal hydrops fetalis. He developed marked respiratory distress secondary to bilateral congenital chylothorax and required pleural drainage, high frequency oscillation and inhaled nitric oxide therapy. He was extubated to non-invasive ventilation by day 14. Read More

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Congenital Chylothorax and Hydrops Fetalis: A Novel Neonatal Presentation of Mutation.

Pediatrics 2021 03;147(3)

Department of Pediatrics, Queen's University, Kingston, Ontario, Canada

Mutations in the gene are known to cause arteriovenous malformations (AVMs), with evidence of associated lymphatic malformations. We report for the first time, to the best of our knowledge, an infant with mutation presenting with hydrops fetalis and chylothorax, but without an associated AVM. Previously, researchers studying rodents have found chylothorax associated with mutations, and, in previous case reports, researchers have reported on infants with mutations born with hydrops fetalis and AVMs. Read More

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Extracorporeal Membrane Oxygenation as a Rescue Therapy for Postoperative Diastolic Dysfunction and Refractory Chylothorax.

ASAIO J 2021 05;67(5):e99-e101

Pediatric Cardiac Intensive Care Unit, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.

This is the first published case, as far as we know, of a term neonate with refractory chylothorax secondary to diastolic dysfunction in the cardiac postoperative period, where extracorporeal membrane oxygenation (ECMO) was used to improve the physiologic derangements, thus allowing resolution of the chylous effusion. The infant was prenatally diagnosed with d-transposition of the great arteries. He was started on prostaglandin infusion and underwent balloon atrial septostomy followed by arterial switch operation. Read More

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Pulmonary Manifestations of Congenital Heart Disease in Children.

Pediatr Clin North Am 2021 02;68(1):25-40

Technology Dependence Center, Division of Pulmonary Medicine, The Perelman School of Medicine at the University of Pennsylvania, Children's Hospital of Philadelphia, 3501 Civic Center Boulevard, Philadelphia, PA 19104, USA. Electronic address:

This review addresses how anomalous cardiovascular anatomy imparts consequences to the airway, respiratory system mechanics, pulmonary vascular system, and lymphatic system. Abnormal formation or enlargement of great vessels can compress airways and cause large and small airway obstructions. Alterations in pulmonary blood flow associated with congenital heart disease (CHD) can cause abnormalities in pulmonary mechanics and limitation of exercise. Read More

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February 2021

Recurrent prenatal PIEZO1-related lymphatic dysplasia: Expanding molecular and ultrasound findings.

Eur J Med Genet 2021 Jan 20;64(1):104106. Epub 2020 Nov 20.

Department of Experimental Medicine, Sapienza University of Rome, Policlinico Umberto I Hospital, Rome, Italy.

Generalized lymphatic dysplasia (GLD), characterized by lymphedema, lymphangiectasias, chylothorax, effusions, represents a recognized cause of fetal hydrops. We describe for the first time recurrent pregnancies showing different ultrasound presentations of lymphatic dysplasia. The first fetus displayed diffuse subcutaneous cysts and septations while the second one presented fetal hydrops. Read More

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January 2021

[Lymphangiomatosis: Rare Cause of Pleural Effusion].

Pneumologie 2021 Feb 24;75(2):138-141. Epub 2020 Jul 24.

Klinik für Pneumologie, Kardiologie und internistische Intensivmedizin, Florence Nightingale Krankenhaus, Kaiserswerther Diakonie, Düsseldorf.

A 33-year-old man presented to us with slowly progressive dyspnea. At the physical examination we found pleural effusion on the right side, lymph edema of the left lower limb and foot and blotchy map-like skin changes. The pleural puncture revealed a chylous effusion. Read More

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February 2021

A homozygous variant in growth and differentiation factor 2 (GDF2) may cause lymphatic dysplasia with hydrothorax and nonimmune hydrops fetalis.

Am J Med Genet A 2020 09 2;182(9):2152-2160. Epub 2020 Jul 2.

Department of Clinical Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

The etiology of nonimmune hydrops fetalis is extensive and includes genetic disorders. We describe a term-born female neonate with late onset extensive nonimmune hydrops, that is, polyhydramnios, edema, and congenital bilateral chylothorax. This newborn was successfully treated with repetitive thoracocentesis, total parenteral feeding, octreotide intravenously and finally surgical pleurodesis and corticosteroids. Read More

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September 2020

Unusual case of chylothorax with unilateral limb swelling.

BMJ Case Rep 2020 Feb 10;13(2). Epub 2020 Feb 10.

Department of Anaesthesiology, General Hospital, Ladakh, India.

Here, we present an unusual case of 26-month male toddler who presented with swelling of right lower limb with painless hyperpigmented patch over right groin of 18 months duration associated with recent onset respiratory distress. Evaluation revealed right chylothorax and MRI revealed altered signal intensity in bones and muscles of right lower limb. Lymphoscintigraphy revealed absence of lymphatic channels in right lower limb. Read More

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February 2020

Thoracic Duct Embolization of a Traumatic Chylous Leak Presenting with Delayed Neck Pain and Swelling.

J Vasc Interv Radiol 2020 01 25;31(1):182-184. Epub 2019 Nov 25.

Division of Interventional Radiology, Department of Radiology, Hospital of the University of Pennsylvania 1 Silverstein, 3400 Spruce St. Philadelphia, PA 19104.

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January 2020

Congenital Chylothorax: Common and Uncommon Findings in an Infant with Chylous Effusions.

Neonatal Netw 2019 Nov;38(6):357-364

Congenital chylothorax is defined as an abnormal accumulation of lymphatic fluid in the pleural space. It is a rare condition in the neonate that causes significant respiratory, nutritional, and immunologic problems resulting in a high mortality rate. Presented here is a case of congenital bilateral chylothorax in a preterm infant. Read More

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November 2019

70-Year-Old Man With Fatigue, Shortness of Breath, and Bilateral Lower Extremity Edema.

Mayo Clin Proc 2019 12 2;94(12):e137-e143. Epub 2019 Nov 2.

Advisor to resident and Consultant in General Internal Medicine, Mayo Clinic, Rochester, MN. Electronic address:

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December 2019

Lymphovenous anastomosis for the treatment of persistent congenital chylothorax in a low-birth-weight infant: A case report.

Medicine (Baltimore) 2019 Oct;98(43):e17575

Division of Plastic and Reconstructive Surgery, Shimane University Faculty of Medicine, Izumo, Shimane, Japan.

Rationale: Chylothorax remains a poorly understood phenomenon, and no optimal treatment or guidelines have been established. This is the first report of treating congenital chylothorax and lymphedema in a low-birth-weight infant by lymphovenous anastomosis (LVA).

Patient Concerns: We report a case of successful LVA for persistent congenital chylothorax and lymphedema resistant to other conservative therapies. Read More

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October 2019

[Adhesive sutures using cyanoacrylate in pleural drains of premature infants].

An Pediatr (Engl Ed) 2020 Jul 7;93(1):52-54. Epub 2019 Aug 7.

Grupo Investigación Perinatología, Instituto de Investigación Sanitaria La Fe, Hospital Universitario y Politécnico La Fe, Valencia, España. Electronic address:

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Lymphangioleiomyomatosis manifesting as refractory chylothorax and chyloperitoneum.

BMJ Case Rep 2019 Jul 11;12(7). Epub 2019 Jul 11.

Division of Medical Education, Department of Medicine, Barnes-Jewish Hospital, Saint Louis, Missouri, USA.

This is a rare case of sporadic lymphangioleiomyomatosis (S-LAM) manifesting as refractory chylothorax and chyloperitoneum. A middle-aged woman with unremarkable medical history presented with respiratory failure, abdominal distension and anasarca. She was found to have high-output chylous effusion that required chest tube drainage, as well as chylous ascites. Read More

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Simultaneous chylous ascites and chylothorax during ramucirumab plus docetaxel chemotherapy in a patient with non-small lung cell cancer.

Int Cancer Conf J 2019 Jul 25;8(3):114-117. Epub 2019 Feb 25.

1Department of Medical Oncology, Graduate School of Medicine, Chiba University, Inohana 1-8-1, Chiba, 260-8670 Japan.

A 69-year-old woman was diagnosed as having non-small cell lung cancer (adenocarcinoma, T1aN3M1b). She had no history of surgery or abdominal trauma. She was treated with ramucirumab (10 mg/kg) plus docetaxel (60 mg/m) intravenously (RAM + DTX) every 3 weeks. Read More

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Woman With Cirrhosis and Shortness of Breath.

Ann Emerg Med 2019 06;73(6):e77-e78

Department of Emergency Medicine, Maine Medical Center, Portland, ME; Tufts University School of Medicine, Portland, ME.

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Rare case of congenital chylothorax and challenges in its management.

BMJ Case Rep 2019 May 22;12(5). Epub 2019 May 22.

Paediatrics, University of Cambridge, Cambridge, UK.

This case describes the difficulties faced in treating recurrent pleural effusions and diagnosing chylothorax in a preterm neonate. The mother of this case was one of the first neonates to undergo in utero pleural shunting for bilateral pleural effusions 30 years ago. She then presented with an antenatal diagnosis of fetal hydrops at 31+1 weeks gestation in her own pregnancy and her baby was delivered 3 days later due to concerns about fetal distress. Read More

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Treatment of Chylothorax with Pleurodesis (A Lesser Known Complication of Behçet's Disease): A Case Report.

J Tehran Heart Cent 2018 Oct;13(4):180-182

Yozgat State Hospital, Yozgat, Turkey.

Behçet's Disease (BD) is a multisystemic vasculitis which usually affects optical, genital, and oral mucosae and often reoccurs intermittently. Chylothorax is a very rare complication of BD which usually causes thrombosis in the major venous system. A 27-year-old man with a 10-year history of BD referred to our cardiovascular surgery department with symptoms of serious aches in the left arm, edema, and apparent veins on the left anterior chest wall. Read More

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October 2018

Yellow nail syndrome resulting from cardiac mitral valve replacement.

J Cardiothorac Surg 2019 Apr 11;14(1):72. Epub 2019 Apr 11.

Department in cardiac surgery hospital of Damascus university, Damascus, Syria.

Background: Yellow nail syndrome is a rare disease with unknown etiology, Attributed to functional anomalies or disturbance in lymphatic drainage. This condition is characterized by triad of nail discoloration, respiratory or intrathoracic manifestations and lymphedema.

Case Presentation: Twenty days after mitral valve replacement for severe rheumatic mitral valve stenosis, 39 years old woman presented with face tenderness and hearing problems besides stuffy and clogged nose and underwent routin rhinosinusitis therapy. Read More

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[Clinical features and prognosis of neonates with nonimmune hydrops fetalis].

Zhongguo Dang Dai Er Ke Za Zhi 2019 Mar;21(3):253-258

Department of Pediatrics, Peking University Third Hospital, Beijing 100191, China.

Objective: To study the clinical features, etiology and prognosis of neonates with nonimmune hydrops fetalis (NIHF).

Methods: A retrospective analysis was performed for the clinical data and outcomes of 23 neonates with NIHF.

Results: Of the 23 neonates with NIHF, 18 (78%) were preterm infants and 5 (22%) were full-term infants; 12 (52%) had birth asphyxia (including 5 cases of severe asphyxia). Read More

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Chylothorax after spinal fusion surgery: A case report and literature review.

Respir Med Case Rep 2019 5;26:260-264. Epub 2019 Feb 5.

Department of Respiratory Medicine, Tokyo Medical University Hospital, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, Japan.

Chylothorax is reported as a postoperative complication, mainly in the field of thoracic surgery, but there are only 14 reports in the field of spinal surgery. A 64-year-old woman underwent spinal fusion surgery by the anterior and posterior approach for her scoliosis. She developed leg edema and right pleural effusion 2 months after the surgery. Read More

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February 2019

Non-Immune Hydrops, Hypotonia, Encephalopathy, and Liver Failure with Novel Compound Heterozygous AHCY Mutations.

Neonatology 2018 17;114(4):337-340. Epub 2018 Aug 17.

Division of Pediatric Clinical Genetics, University of Utah School of Medicine, Salt Lake City, Utah, USA.

A late-preterm infant with a prenatal diagnosis of non-immune hydrops was born with hypotonia, poor respiratory effort, chylothorax, encephalopathy, coagulopathy, progressive hepatic failure, and refractory pulmonary hypertension. Life support was withdrawn at 7 days of life due to multisystem organ failure. Rapid whole exome sequencing revealed novel compound heterozygous mutations in the gene encoding S-adenosylhomocysteine hydrolase (AHCY); each novel variant was carried by an asymptomatic parent. Read More

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September 2019

Chylous complications of various severity and manifestations within diverse compartments in reconstructive vascular surgery #) #) The manuscript is dedicated to Prof. Dr. Z. Halloul.

Pol Przegl Chir 2018 05;90(3):43-48

University Hospital at Magdeburg, Magdeburg (Germany) Dept. of General, Abdominal and Vascular Surgery.

Introduction: Chylous complications, which occur also in the profile of vascularsurgical interventions with considerable frequency, are challenging with regard to their adequate management. Aim & method: Compact short overview on epidemiological, classifying, symptomatic, diagnostic and therapeutic aspects of chylous complications in vascular surgery, based on i) own clinical experiences, ii) a current selection of relevant scientific references and iii) representative case reports from clinical practice. Results (complex patient- & clinical finding-associated aspects): - Basic treatment of lymphedema / postreconstructive edema comprises the complex physical therapy to improve edematous swelling, which need to be usually performed over years. Read More

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Recognition of Neonatal Lymphatic Flow Disorder: Fetal MR Findings and Postnatal MR Lymphangiogram Correlation.

Acad Radiol 2018 11 23;25(11):1446-1450. Epub 2018 Mar 23.

Department of Radiology, Hospital of the University of Pennsylvania, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania.

Rationale And Objectives: This study aimed to describe prenatal and postnatal imaging features and outcomes of neonates with neonatal lymphatic disorders (NLDs).

Materials And Methods: An institutional review board-approved search of the radiology database for patients with NLD identified five patients. Inclusion criteria include prenatal imaging (fetal magnetic resonance [MR] imaging and ultrasound) and postnatal three-dimensional T2 Sampling Perfection with Application optimized Contrasts using different flip angle Evolution (SPACE) and dynamic contrast-enhanced MR lymphangiography within 6 months of life. Read More

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November 2018

An Autopsy Case of Mesenteric Panniculitis with Massive Pleural Effusions.

Am J Case Rep 2018 Jan 4;19:13-20. Epub 2018 Jan 4.

Department of Pathology, Tachikawa General Hospital, Nagaoka, Niigata, Japan.

BACKGROUND Mesenteric panniculitis (MP) is an idiopathic chronic inflammatory condition of the mesentery. The main symptoms include abdominal pain, abdominal distention, weight loss, fever, nausea, and vomiting. The patients also present with chylous ascites in 14% of the cases and chylous pleural effusion (CPE) in very rare occasions. Read More

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January 2018

Treatment of fetal congenital chylothorax: Report of eight cases at a mainland Chinese medical center.

Taiwan J Obstet Gynecol 2017 12;56(6):867-869

Prenatal Diagnosis & Fetal Medicine Center, Guangzhou Women and Children's Medical Center Affiliated to Guangzhou Medical University, Guangzhou, China. Electronic address:

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December 2017

Prenatal factors associated with neonatal survival of infants with congenital chylothorax.

J Perinatol 2018 01 19;38(1):31-34. Epub 2017 Oct 19.

Department of Neonatal Intensive Care, APHP Necker Hospital, Paris, France.

Objectives: Congenital chylothorax is a rare disease and prognostic factors are key element in properly informing parents. This study aimed at determining the prenatal factors associated with neonatal survival in a cohort of liveborn infants with congenital chylothorax.

Study Design: Observational monocentric cohort study including all liveborn neonates consecutively admitted for congenital chylothorax. Read More

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January 2018

Acute Neck Swelling and Chest Pain After Forceful Coughing.

JAMA Surg 2017 10;152(10):976-977

Department of Surgery, The Warren Alpert Medical School, Brown University, Providence, Rhode Island.

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October 2017