12,108 results match your criteria chronic musculoskeletal


The Relationship Between Workload and Non-Contact Musculoskeletal Injury in College Swimmers: A Prospective Cohort Study.

J Athl Train 2021 Jun 15. Epub 2021 Jun 15.

Department of Exercise Science, University of South Carolina, Colombia, SC,

Context: Swimmers are known for high training loads and overuse injuries, but few studies have investigated the relationship between the two at the college level.

Objective: To determine the association between workload and non-contact musculoskeletal injury in college swimmers. We hypothesized (1) higher overall workload (kilometers swum throughout the season) would be associated with increased odds of injury and (2) the ratio of the current week's (acute) workload divided by the current month's (chronic) workload (i. Read More

View Article and Full-Text PDF

Chronic Pelvic Pain in Women: A Review.

JAMA 2021 Jun;325(23):2381-2391

Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles.

Importance: Chronic pelvic pain (CPP) is a challenging condition that affects an estimated 26% of the world's female population. Chronic pelvic pain accounts for 40% of laparoscopies and 12% of hysterectomies in the US annually even though the origin of CPP is not gynecologic in 80% of patients. Both patients and clinicians are often frustrated by a perceived lack of treatments. Read More

View Article and Full-Text PDF

The axial spondyloarthritis clinical phenotype in idiopathic hypoparathyroidism: critical review of concept that muscular hypercontractility can induce enthesopathy lesions.

Clin Exp Rheumatol 2021 Jun 8. Epub 2021 Jun 8.

Family Medicine Resident, Niagara Falls Memorial Medical Center, Niagara Falls, NY, USA.

Idiopathic hypoparathyroidism (iH-PoPT) is a rare condition infrequently associated with axial spondyloarthritis (SpA) which may mimic ankylosing spondylitis (AS). Axial SpA is a unifying clinical term for chronic inflammatory spinal disorders, although biomechanical factors may play a role. The primary objective of this review is to critically describe the iHPoPT/SpA phenotype defined by established criteria and its differentiation from AS. Read More

View Article and Full-Text PDF

Reduction in Pain Inhibitory Modulation and Cognitive-Behavioral Changes in Patients With Chronic Low Back Pain: A Case-Control Study.

Pain Manag Nurs 2021 Jun 11. Epub 2021 Jun 11.

Department of Physical Therapy, Federal University of Delta of Parnaíba, Parnaíba, Piauí, Brazil; Biomedical Master Science Program, Federal University of Delta of Parnaíba, Parnaíba, Piauí, Brazil. Electronic address:

Background: Recent studies indicate that the assessment of conditioned pain modulation (CPM) responses and emotional factors can provide important information regarding chronification mechanisms, choices for more efficient therapeutic strategies, and clinical variables supporting a therapeutic prognosis.

Aims: To investigate the impact of nonspecific chronic low back pain (NSCLBP) on CPM and psychosocial factors in individuals with NSCLBP compared with healthy controls.

Design: Case-control study. Read More

View Article and Full-Text PDF

What Is the Optimal Irrigation Solution in the Management of Periprosthetic Hip and Knee Joint Infections?

J Arthroplasty 2021 May 26. Epub 2021 May 26.

Department of Orthopedics, Rothman Orthopedics, Philadelphia, PA.

Background: Thorough irrigation and debridement using an irrigation solution is a well-established treatment for both acute and chronic periprosthetic joint infections (PJIs). In the absence of concrete data, identifying the optimal irrigation agent and protocol remains challenging.

Methods: A thorough review of the current literature on the various forms of irrigations and their additives was performed to evaluate the efficacy and limitations of each solution as pertaining to pathogen eradication in the treatment of PJI. Read More

View Article and Full-Text PDF

Visceral pain, mechanisms, and implications in musculoskeletal clinical practice.

Med Hypotheses 2021 Jun 6;153:110624. Epub 2021 Jun 6.

Health Sciences Faculty, Universidad San Sebastián, General Lagos 1022 Valdivia, 56 2632500, Chile. Electronic address:

The global impact of visceral pain is extremely high, representing a significant portion of all forms of chronic pain. In musculoskeletal practice, at least one-third of people with persistent noncancerous pain report recurrent abdominal, pelvic, or chest pain symptoms. Visceral pain can be felt in several different areas of the body and can migrate throughout a region, even though the site of origin does not appear to change. Read More

View Article and Full-Text PDF

A systematic review of the effectiveness of yoga on pain, physical function, and quality of life in older adults with chronic musculoskeletal conditions.

Musculoskeletal Care 2021 Jun 14. Epub 2021 Jun 14.

University of Salford, School of Health & Society Mary Seacole Building, Frederick Road Campus, UK.

Objectives: Exercise interventions suitable for older adults can help to slow and manage age-related conditions. This systematic review looks at age-related musculoskeletal conditions in a population with a mean age over 50 years, evaluating the effectiveness of yoga for pain, physical function, and quality of life.

Methods: CENTRAL,CINAHL, Pubmed, PsycInfo, SCOPUS, Sports Discus, Web of Science Core Collection, and Google Scholar were searched. Read More

View Article and Full-Text PDF

Effects of motivational interviewing with conventional physical therapy on rehabilitation of chronic musculoskeletal disorders: A quasi-experimental study.

J Pak Med Assoc 2021 Apr;71(4):1123-1127

Rural Health Centre, Manga Mandi District, Lahore, Pakistan.

Objective: To compare the effects of motivational interviewing with conventional physical therapy in the rehabilitation of chronic musculoskeletal disorders compared to conventional physical therapy alone.

Methods: The quasi-experimental study was conducted from September 2017 to March 2018 after approval from the University of Health Sciences, Lahore, Pakistan, and comprised patients with chronic musculoskeletal disorders enrolled from various outpatient physical therapy clinics in Lahore. The subjects were alternatively allocated to intervention group A and control group B, with the former receiving motivational interviewing along with conventional physical therapy, and the latter receiving conventional physical therapy alone. Read More

View Article and Full-Text PDF

The Evolution of Technology and Physical Inactivity: The Good, the Bad, and the Way Forward.

Front Public Health 2021 28;9:655491. Epub 2021 May 28.

Institute for Health and Sport (iHeS), Victoria University, Melbourne, VIC, Australia.

Since the beginning of time people explored and developed new technologies to make their activities of daily living less labour intense, more efficient and, consequently, more sedentary. In addition, technological advances in medicine throughout history have led to a substantial increase in life expectancy. However, the combination of increased sedentary behaviour and increased life-expectancy resulted in a sharp increase in overweight and obesity related chronic conditions and illness. Read More

View Article and Full-Text PDF

Effect of massage therapy on pain and quality of life in dogs: A cross sectional study.

Vet Rec 2021 Jun 13:e586. Epub 2021 Jun 13.

Meryll House, Canine Massage Therapy Centre Ltd, Worcestershire, UK.

Background: Clinical canine massage involves muscle tissue manipulation and fascial release techniques to rehabilitate injured soft tissues. Quantitative efficacy data are lacking. This cross-sectional study aimed to determine how dogs respond to canine massage therapy practiced by Canine Massage Guild UK practitioners. Read More

View Article and Full-Text PDF

Implications of Ehlers Danlos Syndrome in a Patient with Mayer-Rokitansky-Küster-Hauser Syndrome.

J Pediatr Adolesc Gynecol 2021 Jun 10. Epub 2021 Jun 10.

Baylor College of Medicine, Division of Pediatric and Adolescent Gynecology, Houston, TX, USA.

Background: Ehlers Danlos syndromes (EDS) are a heterogenous group of connective tissue disorders characterized by defective collagen production. Patients with EDS have lax and fragile connective tissue in their joints, skin, blood vessels and hollow organs. This can lead to, among other complications, joint hypermobility, aneurysms, organ prolapse and musculoskeletal chronic pain. Read More

View Article and Full-Text PDF

Social factors and pain worsening: a retrospective cohort study.

Br J Anaesth 2021 Jun 9. Epub 2021 Jun 9.

Department of Preventive Medicine, University of Santiago de Compostela, Santiago de Compostela, Spain; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBER-ESP), Madrid, Spain; Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain. Electronic address:

Background: Pain, specifically chronic pain, is a major public health issue worldwide with considerable health-related consequences and large economic impact. The relation between socioeconomic status and pain occurrence is well established. However, little is known on the relation between socioeconomic factors and worsening of pain, including progression from non-chronic pain to chronic pain. Read More

View Article and Full-Text PDF

Frequency of Fabry disease in a juvenile idiopathic arthritis cohort.

Pediatr Rheumatol Online J 2021 Jun 12;19(1):91. Epub 2021 Jun 12.

Rheumatology Unit, School of Medical Sciences and University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.

Background: Fabry disease (FD) is a rare, X-linked, multisystemic lysosomal storage disorder (LSD) that results from a deficiency in the hydrolase alpha-galactosidase A (⍺-GalA). During childhood, classic FD symptomatology is rare. The majority of children may show non-specific symptoms, including in the musculoskeletal system. Read More

View Article and Full-Text PDF

Orofacial musculoskeletal pain: An evidence-based bio-psycho-social matrix model.

Neurosci Biobehav Rev 2021 Jun 9;128:12-20. Epub 2021 Jun 9.

Laboratory of Neuroimmune Interface of Pain Research, Faculdade São Leopoldo Mandic, Instituto e Centro De Pesquisas São Leopoldo Mandic, Campinas, SP, Brazil.

Pain is a multidimensional experience comprising sensory-discriminative, affective-motivational, and cognitive-evaluative dimensions. Clinical and research findings have demonstrated a complex interplay between social burdens, individual coping strategies, mood states, psychological disorders, sleep disturbances, masticatory muscle tone, and orofacial musculoskeletal pain. Accordingly, current classification systems for orofacial pain require psychosocial assessments to be an integral part of the multidimensional diagnostic process. Read More

View Article and Full-Text PDF

Self-management at the core of back pain care: 10 key points for clinicians.

Braz J Phys Ther 2021 May 24. Epub 2021 May 24.

Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense M, Denmark; Chiropractic Knowledge Hub, Odense M, Denmark.

Background: A paradigm shift away from clinician-led management of people with chronic disorders to people playing a key role in their own care has been advocated. At the same time, good health is recognised as the ability to adapt to changing life circumstances and to self-manage. Under this paradigm, successful management of persistent back pain is not mainly about clinicians diagnosing and curing patients, but rather about a partnership where clinicians help individuals live good lives despite back pain. Read More

View Article and Full-Text PDF

[Analysis of potentially inappropriate prescriptions according to the START criteria in nursing homes].

Rev Esp Geriatr Gerontol 2021 Jun 8. Epub 2021 Jun 8.

Universidad de Valencia, Valencia, España; INCLIVA Instituto de Investigación Sanitaria. Hospital Clínico Universitario de Valencia, Valencia, España; Dirección Médica Hospital Clínico Universitario de Valencia, Valencia, España; Centro de Investigación Biomédica en red Epidemiología y Salud Pública (CIBERESP), España.

Background And Objective: The potentially inappropriate prescription by omission of a drug is defined as the failure to prescribe drugs that are clinically indicated. The objective of this article is to describe and analyse the evolution of inappropriate prescriptions by omission in nursing homes of a health department.

Material And Methods: Retrospective observational descriptive study carried out in nursing homes of the Valencia-Clínico-Malvarrosa health department during the period 2016-2018. Read More

View Article and Full-Text PDF

Physiotherapists' perspectives on barriers to implementation of direct access of physiotherapy services in the United Arab Emirates: A cross-sectional study.

PLoS One 2021 11;16(6):e0253155. Epub 2021 Jun 11.

Department of Physiotherapy, College of Health sciences, University of Sharjah, Sharjah, UAE.

Background: There are two primary ways of accessing physiotherapy for service users around the world. The direct access, as opposed to the indirect access which requires a referral from a general physician, has several merits including better quality, timeliness, cost effectiveness of treatment and better probability of preventing acute conditions from turning into chronic ailments. Despite these benefits, several countries including the UAE, do not allow direct access to physiotherapists. Read More

View Article and Full-Text PDF

Leprosy-Related Chronic Arthritis with an Abundance of in the Synovial Fluid: A Rare Case.

Int Med Case Rep J 2021 3;14:371-376. Epub 2021 Jun 3.

Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Hasan Sadikin General Hospital, Bandung, West Java, 40161, Indonesia.

Bone and joint involvements are the most common manifestation in leprosy, after cutaneous and neurological manifestations, yet are underdiagnosed and rarely reported. We report a case of lepromatous leprosy in a 41-year-old male with bone and joint changes. Physical examination revealed a leonine face, madarosis, hypesthetic hypopigmented macules on the back, and swelling of fingers and toes. Read More

View Article and Full-Text PDF

Fourteen days of smoking cessation improves muscle fatigue resistance and reverses markers of systemic inflammation.

Sci Rep 2021 Jun 10;11(1):12286. Epub 2021 Jun 10.

Department of Life Sciences, Centre of Musculoskeletal Sciences and Sport Medicine, Manchester Metropolitan University, John Dalton Building; Chester Street, Manchester, M1 5GD, UK.

Cigarette smoking has a negative effect on respiratory and skeletal muscle function and is a risk factor for various chronic diseases. To assess the effects of 14 days of smoking cessation on respiratory and skeletal muscle function, markers of inflammation and oxidative stress in humans. Spirometry, skeletal muscle function, circulating carboxyhaemoglobin levels, advanced glycation end products (AGEs), markers of oxidative stress and serum cytokines were measured in 38 non-smokers, and in 48 cigarette smokers at baseline and after 14 days of smoking cessation. Read More

View Article and Full-Text PDF

Extra-skeletal effects of dietary calcium: Impact on the cardiovascular system, obesity, and cancer.

Adv Food Nutr Res 2021 18;96:1-25. Epub 2021 Mar 18.

Department of Food and Human Nutritional Sciences, Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba, Winnipeg, MB, Canada. Electronic address:

Calcium is well known to be integral to bone and muscle health, with deleterious effects such as osteoporosis associated with inadequate calcium intake. Recent studies have also highlighted the significant effects of calcium in extra-musculoskeletal functioning, including the cardiovascular system, obesity, and cancer. Calcium impacts the cardiovascular system as an antagonist associated with a reduction in hypertension, increase vasodilation, and improvement in blood vessel function when obtained in the diet as an organic source, through food. Read More

View Article and Full-Text PDF

What is the burden of osteomyelitis in Germany? An analysis of inpatient data from 2008 through 2018.

BMC Infect Dis 2021 Jun 10;21(1):550. Epub 2021 Jun 10.

Department for Trauma Surgery, University Medical Center Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany.

Background: The epidemiology of osteomyelitis in Germany is unknown, which makes it difficult to estimate future demands. Therefore, we aimed to analyse how the numbers of cases have developed over the last decade as a function of osteomyelitis subtype, age group, gender, and anatomical localization.

Methods: Osteomyelitis rates were quantified based on annual ICD-10 diagnosis codes from German medical institutions between 2008 through 2018, provided by the Federal Statistical Office of Germany (Destatis). Read More

View Article and Full-Text PDF

Collagen VI as a driver and disease biomarker in human fibrosis.

FEBS J 2021 Jun 9. Epub 2021 Jun 9.

Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Science, University of Oxford, UK.

Fibrosis of visceral organs such as the lungs, heart, kidneys and liver remains a major cause of morbidity and mortality and is also associated with many other disorders, including cancer and metabolic disease. In this review, we focus upon the microfibrillar collagen VI, which is present in the extracellular matrix (ECM) of most tissues. However, expression is elevated in numerous fibrotic conditions, such as idiopathic pulmonary disease (IPF), and chronic liver and kidney diseases. Read More

View Article and Full-Text PDF

Four-Dimensional CT Analysis of Dorsal Intercalated Segment Instability in patients with Suspected Scapholunate Instability.

J Wrist Surg 2021 Jun 22;10(3):234-240. Epub 2021 Jan 22.

Guilloz Imaging Department, Central Hospital, Nancy University Hospital, Nancy, France.

 In this study we sought to evaluate the contribution of dynamic four-dimensional computed tomography (4DCT) relative to the standard imaging work-up for the identification of the dorsal intercalated segment instability (DISI) in patients with suspected chronic scapholunate instability (SLI).  Forty patients (22 men, 18 women; mean age 46.5 ± 13. Read More

View Article and Full-Text PDF

Infographic. Benefits and harms of exercise therapy in people with multimorbidity.

Br J Sports Med 2021 Jun 9. Epub 2021 Jun 9.

The Research Unit PROgrez, Department of Physiotherapy and Occupational Therapy, Næstved-Slagelse-Ringsted Hospitals, Slagelse, Denmark.

View Article and Full-Text PDF

Methods to assess disease activity and severity in cutaneous chronic graft-versus-host disease: a critical literature review.

Transplant Cell Ther 2021 Jun 6. Epub 2021 Jun 6.

Department of Dermatology, Mayo Clinic, Rochester, MN, USA. Electronic address:

Background: Chronic graft-versus-host disease (cGVHD), a potentially debilitating complication of hematopoietic cell transplantation, confers increased risk for mortality. While treatment decisions rely on an accurate assessment of disease activity/severity, validated methods of assessing cutaneous cGVHD activity/severity appear to be limited.

Objective: We aimed to identify and evaluate current data on the assessment of disease activity/severity in cutaneous cGVHD Study Design: Using modified PRISMA methods, we performed critical literature review for relevant articles. Read More

View Article and Full-Text PDF

Impaired skeletal muscle fatigue resistance during cardiac hypertrophy is prevented by functional overload- or exercise-induced functional capillarity.

J Physiol 2021 Jun 9. Epub 2021 Jun 9.

School of Biomedical Sciences, University of Leeds, UK.

Key Points: Capillary rarefaction is hypothesised to contribute to impaired exercise tolerance in cardiovascular disease, but it remains a poorly exploited therapeutic target for improving skeletal muscle performance. Using an abdominal aortic coarctation rat model of compensatory cardiac hypertrophy, we determine the efficacy of aerobic exercise for the prevention of, and mechanical overload for restoration of hind limb muscle fatigue resistance and microvascular impairment in the early stages of heart disease. Impaired muscle fatigue resistance was found after development of cardiac hypertrophy, but this impairment was prevented by low intensity aerobic exercise and recovered after mechanical stretch due to muscle overload. Read More

View Article and Full-Text PDF

Trends in clinical trials performed in Chile.

Rev Med Chil 2021 Jan;149(1):110-118

Department of Bioethics, The Clinical Center, National Institutes of Health, United States.

Background: An increasingly large proportion of clinical trials is being conducted at non-traditional geographic regions such as Latin America. However, concerns have been raised that hosting countries may lack adequate research regulations and that clinical trials may not address local health needs. In this context, Chile has been hosting a relatively large proportion of clinical trials and has introduced new regulatory protections. Read More

View Article and Full-Text PDF
January 2021

Effect of Systemic Administration of Granulocyte Colony-Stimulating Factor on a Chronic Partial-Thickness Cartilage Defect in a Rabbit Knee Joint.

Cartilage 2021 Jun 9:19476035211021905. Epub 2021 Jun 9.

Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Chiba, Japan.

Objective: Cartilage lesions in the knee joint can lead to joint mechanics changes and cause knee pain. Bone marrow stimulation (BMS) promotes cartilage regeneration by perforating the subchondral bone just below the injury and inducing bone marrow cells. This study aimed to investigate whether systemic administration of granulocyte colony-stimulating factor (G-CSF) with BMS improves repair of chronic partial-thickness cartilage defects (PTCDs). Read More

View Article and Full-Text PDF

A scoping review to ascertain the parameters for an evidence synthesis of psychological interventions to improve work and wellbeing outcomes among employees with chronic pain.

Health Psychol Behav Med 2021 Jan 28;9(1):25-47. Epub 2021 Jan 28.

Institute of Health and Wellbeing, University of Glasgow, Glasgow, Scotland, UK.

Background: Psychological interventions have mixed effects on improving employee outcomes, partly due to significant variability across studies and a lack of focus on mechanisms of action. This scoping review reports on the parameters of these interventions and examines intervention content to bring clarity to this heterogeneous topic area and direct future systematic review work.

Method: Six databases were searched (Cinahl, Cochrane, Embase, Medline, PsychINFO and Web of Science) from April 2010 to August 2020, and a grey literature search was undertaken. Read More

View Article and Full-Text PDF
January 2021

Hyperuricemia, urate-lowering therapy, and kidney outcomes: a systematic review and meta-analysis.

Ther Adv Musculoskelet Dis 2021 25;13:1759720X211016661. Epub 2021 May 25.

Division of Clinical Immunology and Rheumatology, Department of Medicine at the School of Medicine and the Department of Epidemiology at the School of Public Health, University of Alabama at Birmingham, Faculty Office Tower 805B, 510 20th Street S., Birmingham, AL 35294-0022, USA.

Background: Contradictory evidence exists for association of hyperuricemia and kidney function. To investigate the association of hyperuricemia and kidney function decline (hyperuricemia question) and effect of urate-lowering therapies (ULTs) on kidney function (ULT question), we performed a systematic review and meta-analysis.

Methods: , , , and were searched from inception to July 2020. Read More

View Article and Full-Text PDF