Brain Behav Immun 2021 Jul 31. Epub 2021 Jul 31.
Axe neurosciences, Centre de recherche du CHU de Québec-Université Laval, Québec, QC, Canada; Molecular Medicine Department, Université Laval, Québec City, QC, Canada; Division of Medical Sciences, University of Victoria, Victoria, BC, Canada; The Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, BC, Canada. Electronic address:
Chronic psychological stress is one of the most important triggers and environmental risk factors for neuropsychiatric disorders. Chronic stress can influence all organs via the secretion of stress hormones, including glucocorticoids by the adrenal glands, which coordinate the stress response across the body. In the brain, glucocorticoid receptors (GR) are expressed by various cell types including microglia, which are its resident immune cells regulating stress-induced inflammatory processes. Read More