48,853 results match your criteria chinese han


Nurse-led exercise and cognitive-behavioral care against nurse-led usual care between and after chemotherapy cycles in Han Chinese women of ovarian cancer with moderate to severe levels of cancer-related fatigue: A retrospective analysis of the effectiveness.

Medicine (Baltimore) 2021 Nov;100(44):e27317

Department of Nursing, Shanghai Fourth People's Hospital, No. 1279 Sanmen Road, Hongkou District, Shanghai, China.

Abstract: Women with ovarian cancer are reported to fatigue over time. Moderate to severe levels of cancer-related fatigue is fluent in Han Chinese patients with cancer. Comprehensive Cancer Network guidelines are recommending exercise and cognitive behavioral therapy to reduce cancer-related fatigue. Read More

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November 2021

Suppressed farnesoid X receptor by iron overload in mice and humans potentiates iron-induced hepatotoxicity.

Hepatology 2021 Dec 6. Epub 2021 Dec 6.

School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, 300072, China.

Background And Aims: Iron overload is a frequent finding in the general population. As the major iron storage site, liver is subject to iron toxicity. Farnesoid X receptor (FXR) regulates bile acid metabolism and is implicated in various liver diseases. Read More

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December 2021

Selection of OSA-specific pronunciations and assessment of disease severity assisted by machine learning.

J Clin Sleep Med 2021 Dec 7. Epub 2021 Dec 7.

Beijing Tongren Hospital, Capital Medical University, Beijing 100730, People's Republic of China.

Study Objectives: To screen all of the obstructive sleep apnea (OSA)-characteristic pronunciations, explore the pronunciations which provide a better OSA classification effect than those used previously, and further clarify the correlation between speech signals and OSA.

Methods: A total of 158 adult male Mandarin native speakers who completed polysomnography at the Sleep Medicine Center of Beijing Tongren Hospital from November 15, 2019 to January 19, 2020 were enrolled in this study. All Chinese syllables were collected from each participant in the sitting position. Read More

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December 2021

A novel genetic variant potentially altering the expression of MANBA in the cerebellum associated with attention deficit hyperactivity disorder in Han Chinese children.

World J Biol Psychiatry 2021 Dec 6:1-39. Epub 2021 Dec 6.

Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.

Objectives: To get additional insight into the genetic factors of attention deficit hyperactivity disorder (ADHD).

Methods: First, we performed a transcriptome-wide association study (TWAS) integrating human cerebellum-specific variant-expression/splicing correlations to identify ADHD susceptibility genes. Then, the associations between expression/splicing quantitative trait loci (eQTLs/sQTLs) of the transcriptome-wide significant genes and ADHD were observed in a case-control study of Han Chinese children. Read More

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December 2021

Automatic detection of kikuchi bands based on radon transform and PPHT.

J Microsc 2021 Dec 6. Epub 2021 Dec 6.

School of Computer Engineering and Science, Shanghai University.

The information of crystal structure and orientation can be provided by analyzing the EBSD (electron backscatter diffraction) patterns which are obtained with the EBSD devices. The reliability and accuracy of the information relies on the location of bands and intersections of the EBSD patterns. In this study, a method is proposed to automatically obtain the locations and intersections of the EBSD patterns, i. Read More

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December 2021

Ad-Apoptin-hTERTp-E1a Regulates Autophagy Through the AMPK-mTOR-eIF4F Signaling Axis to Reduce Drug Resistance of MCF-7/ADR Cells.

Front Mol Biosci 2021 19;8:763500. Epub 2021 Nov 19.

Academician Workstation of Jilin Province, Changchun University of Chinese Medicine, Changchun, China.

Ad-VT (Ad-Apoptin-hTERTp-E1a) is a type of oncolytic adenovirus with dual specific tumor cell death ability. It can effectively induce cell death of breast cancer cells and has better effect when used in combination with chemotherapy drugs. However, it has not been reported whether Ad-VT reduces the resistance of breast cancer cells to chemotherapy drugs. Read More

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November 2021

Cause Analysis and Diagnosis and Treatment of Intestinal Fistulas After Ultrasound-Guided Microwave Ablation of Abdominopelvic Lesions.

Front Surg 2021 19;8:675585. Epub 2021 Nov 19.

Department of Interventional Ultrasound, Chinese People's Liberation Army General Hospital, Beijing, China.

To determine the cause and high-risk factors for the development of intestinal fistulas (IFs) after ultrasound-guided microwave ablation (MA) of abdominopelvic lesions, and to identify effective prophylactic and therapeutic actions. Clinical data were collected from patients with an IF after ultrasound-guided MA of abdominopelvic lesions in our hospital from January 1, 2010 to December 31, 2018. The cause, diagnosis, and treatment of IFs in these patients were analyzed. Read More

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November 2021

Temporal Relationship Between Changes in Serum Calcium and Hypercholesteremia and Its Impact on Future Brachial-Ankle Pulse Wave Velocity Levels.

Front Nutr 2021 17;8:754358. Epub 2021 Nov 17.

Division of Clinical Nutrition, The First Affiliated Hospital of Harbin Medical University, Harbin, China.

The high levels of serum calcium and cholesterol are the important risk factors of cardiovascular disease (CVD), which frequently influence each other during the development of CVD. However, few studies have examined their temporal relationship to confirm the precursor, and it is still largely unknown whether and how their temporal relationship would influence the development of CVD. This study aimed to establish the temporal relationship between the changes in serum calcium and cholesterol using the longitudinal cohort data, and examine whether this temporal relationship influenced the arterial elasticity indicated by brachial-ankle pulse wave velocity (baPWV). Read More

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November 2021

The Health Effect of the Number of Children on Chinese Elders: An Analysis Based on Hukou Category.

Front Public Health 2021 16;9:700024. Epub 2021 Nov 16.

School of International and Public Affairs, Shanghai Jiaotong University, Shanghai, China.

Based on the 2018 China Health and Retirement Longitudinal Study (CHARLS 2018), from the perspective of urban-rural disparity, this paper investigates how fertility affects Chinese elders' health. We exploit the enactment of the one-child policy in 1979 to construct instrumental variables capturing the health effect of having only one child rather than multiple children. The empirical results show that the health condition of rural elders having only one child is worse than elders having multiple children, while the negative health effect of lower fertility becomes statistically insignificant for urban elderly parents. Read More

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November 2021

The circRAB3IP Mediated by eIF4A3 and LEF1 Contributes to Enzalutamide Resistance in Prostate Cancer by Targeting miR-133a-3p/miR-133b/SGK1 Pathway.

Front Oncol 2021 15;11:752573. Epub 2021 Nov 15.

Department of Urology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

An increasing number of studies have shown that circRNAs are closely related to the carcinogenesis and development of prostate cancer (PCa). However, little is known about the effect of the biological functions of circRNAs on the enzalutamide resistance of PCa. Through bioinformatic analysis and experiments, we investigated the expression pattern of circRNAs in enzalutamide-resistant PCa cells. Read More

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November 2021

Cancer-Associated Fibroblasts Promote the Upregulation of PD-L1 Expression Through Akt Phosphorylation in Colorectal Cancer.

Front Oncol 2021 19;11:748465. Epub 2021 Nov 19.

Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Peking Union Medical College, Beijing, China.

Upregulation of immune checkpoint proteins is one of the main mechanisms for tumor immune escape. The expression of programmed death ligand-1 (PD-L1) in colorectal cancer (CRC) is higher than in normal colorectal epithelial tissue, and patients with higher PD-L1 expression have a poorer prognosis. Additionally, PD-L1 expression in CRC is affected by the tumor microenvironment (TME). Read More

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November 2021

Elevated DNA Polymerase Delta 1 Expression Correlates With Tumor Progression and Immunosuppressive Tumor Microenvironment in Hepatocellular Carcinoma.

Front Oncol 2021 11;11:736363. Epub 2021 Nov 11.

Department of Transplantation, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Background And Objective: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and the DNA polymerase delta (POLD) family is significantly related to cancer prognosis. This study aimed to explore the significance of the POLD family in HCC the DNA damage repair (DDR) pathway.

Methods: Data mining was conducted using bioinformatics methods. Read More

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November 2021

High-Quality Genomes and High-Density Genetic Map Facilitate the Identification of Genes From a Weedy Rice.

Front Plant Sci 2021 19;12:775051. Epub 2021 Nov 19.

National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.

Genes have been lost or weakened from cultivated rice during rice domestication and breeding. Weedy rice ( f. ) is usually recognized as the progeny between cultivated rice and wild rice and is also known to harbor an gene pool for rice breeding. Read More

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November 2021

Insight Between the Epigenetics and Transcription Responding of Cotton Hypocotyl Cellular Elongation Under Salt-Alkaline Stress.

Front Plant Sci 2021 11;12:772123. Epub 2021 Nov 11.

State Key Laboratory of Cotton Biology/Institute of Cotton Research of Chinese Academy of Agricultural Sciences/Zhengzhou Research Base, School of Agricultural Sciences, Zhengzhou University/Key Laboratory for Cotton Genetic Improvement, MOA, Anyang, China.

is a cultivated cotton not only known for producing superior fiber but also for its salt and alkaline resistance. Here, we used Whole Genome Bisulfite Sequencing (WGBS) technology to map the cytosine methylation of the whole genome of the hypocotyl at single base resolution. The methylation sequencing results showed that the mapping rates of the three samples were 75. Read More

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November 2021

The Response of Plants and Mycorrhizal Fungi to Nutritionally-Heterogeneous Environments Are Regulated by Nutrient Types and Plant Functional Groups.

Front Plant Sci 2021 15;12:734641. Epub 2021 Nov 15.

Soil Science and Plant Nutrition, UWA School of Agriculture and Environment, The University of Western Australia, Perth, WA, Australia.

Nutrient type and plant functional group are both important in influencing proliferation of roots or hyphae and their benefit to plant growth in nutritionally heterogeneous environments. However, the studies quantifying relative importance of roots vs. hyphae affecting the plant response to nutrient heterogeneity are lacking. Read More

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November 2021

GII.P16-GII.2 Recombinant Norovirus VLPs Polarize Macrophages Into the M1 Phenotype for Th1 Immune Responses.

Front Immunol 2021 18;12:781718. Epub 2021 Nov 18.

Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.

Norovirus (NoV) is a zoonotic virus that causes diarrhea in humans and animals. Outbreaks in nosocomial settings occur annually worldwide, endangering public health and causing serious social and economic burdens. The latter quarter of 2016 witnessed the emergence of the GII. Read More

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November 2021

Dynamic Process of Secondary Pulmonary Infection in Mice With Intracerebral Hemorrhage.

Front Immunol 2021 19;12:767155. Epub 2021 Nov 19.

College of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.

Stroke is a common central nervous system disease in clinical practice. Stroke patients often have infectious complications, such as pneumonia and infections of the urinary tract and gastrointestinal tract. Although it has been shown that translocation of the host gut microbiota to the lungs and immune dysfunction plays a vital role in the development of infection after ischemic stroke, the occurrence and mechanism of pulmonary infection at different time points after hemorrhagic cerebral remain unclear. Read More

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November 2021

Insights Into Mechanism of the Naphthalene-Enhanced Biodegradation of Phenanthrene by sp. SL-6 Based on Omics Analysis.

Front Microbiol 2021 17;12:761216. Epub 2021 Nov 17.

Graduate School, Chinese Academy of Agricultural Sciences, Beijing, China.

The existence of polycyclic aromatic hydrocarbons (PAHs) in contaminated environment is multifarious. At present, studies of metabolic regulation focus on the degradation process of single PAH. The global metabolic regulatory mechanisms of microorganisms facing coexisting PAHs are poorly understood, which is the major bottleneck for efficient bioremediation of PAHs pollution. Read More

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November 2021

Compelling Evidence Linking CD40 Gene With Graves' Disease in the Chinese Han Population.

Front Endocrinol (Lausanne) 2021 18;12:759597. Epub 2021 Nov 18.

Department of Molecular Diagnostic and Endocrinology, The Core Laboratory in Medical Center of Clinical Research, The Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Mutations in have been widely reported to be risk factors for Graves' disease (GD). The gene, along with its cognate ligand CD40L, may regulate pro-inflammatory and immune responses. Rs1883832, located at the -1 position of the Kozak sequence, is the most well-studied single nucleotide polymorphism (SNP) of , and has been confirmed to predispose those with the alteration to GD, regardless of ethnicity. Read More

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November 2021

Challenges Faced by Emergency Physicians in China: An Observation From the Perspective of Burnout.

Front Psychiatry 2021 17;12:766111. Epub 2021 Nov 17.

Research Unit of Island Emergency Medicine, Chinese Academy of Medical Sciences (No. 2019RU013), Hainan Medical University, Haikou, China.

Burnout is considered a global problem, particularly in the emergency health sector; however, no large-sample cross-sectional study has assessed the prevalence of burnout among emergency physicians and its associated factors. A nationally representative cross-sectional survey of 15,243 emergency physicians was conducted in 31 provinces across China between July and September 2019. Multiple linear regression analysis was performed to identify correlates of burnout. Read More

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November 2021

Association of Neurotensin Receptor 1 Gene Polymorphisms With Defense Mechanisms in Healthy Chinese.

Front Psychiatry 2021 17;12:762276. Epub 2021 Nov 17.

Department of Psychiatry, The First Affiliated Hospital of China Medical University, Shenyang, China.

In the central nerve system, neurotensin (NT), and neurotensin receptor 1 (NTR1) modulate the dopamine system. Gene variations in the dopamine system have been demonstrated to influence certain defense mechanisms, but no studies have investigated possible effect of gene polymorphisms in the biological determination of these defenses. The present study therefore examined this link. Read More

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November 2021

The Positivity Rate of IA-2A and ZnT8A in the Chinese Han Population With Type 1 Diabetes Mellitus: Association With rs1143627 and rs1143643 Polymorphisms in the IL1B Gene.

Front Pharmacol 2021 11;12:729890. Epub 2021 Nov 11.

National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology (Central South University), Ministry of Education, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, China.

To investigate the association between susceptibility to type 1 diabetes mellitus (T1DM) and polymorphisms (rs1143627 and rs1143643) in the interleukin 1 beta (IL1B) gene in the Chinese Han population. The Meso Scale Discovery (MSD) method was used to detect the concentration of IL-1β in 24 T1DM patients and 27 healthy controls. MassARRAY was used to analyze the polymorphisms in the IL1B gene in 510 patients with classic T1DM and 531 healthy controls. Read More

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November 2021

Activation and Role of Astrocytes in Ischemic Stroke.

Front Cell Neurosci 2021 17;15:755955. Epub 2021 Nov 17.

Department of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.

Ischemic stroke refers to the disorder of blood supply of local brain tissue caused by various reasons. It has high morbidity and mortality worldwide. Astrocytes are the most abundant glial cells in the central nervous system (CNS). Read More

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November 2021

A Web-Based Survey on Factors for Unvaccination and Adverse Reactions of SARS-CoV-2 Vaccines in Chinese Patients with Psoriasis.

J Inflamm Res 2021 27;14:6265-6273. Epub 2021 Nov 27.

Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.

Purpose: Vaccination is one of the most important strategy to prevent infections and control epidemics, but it also raises concerns about safety in patients receiving treatments. This study aimed to investigate the rate and factors for unvaccination, as well as adverse reactions and deterioration of disease after SARS-CoV-2 vaccination in psoriatic patients.

Methods: A web-based questionnaire survey on SARS-CoV-2 vaccination, adverse reactions, and self-reported change of disease condition after vaccination in patients with psoriasis was conducted. Read More

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November 2021

The Tokyo 2020 Terminology of Liver Anatomy and Resections: Updates of the Brisbane 2000 system.

J Hepatobiliary Pancreat Sci 2021 Dec 6. Epub 2021 Dec 6.

HPB and Liver Transplant Unit, Clínica Universidad de Navarra, Pamplona, Spain.

Background: The Brisbane 2000 Terminology for Liver Anatomy and Resections, based on Couinaud's segments, did not address how to identify segmental borders and anatomic territories of less than one segment. Smaller anatomic resections including segmentectomies and subsegmentectomies, have not been well defined. The advent of minimally invasive liver resection has enhanced the possibilities of more precise resection due to a magnified view and reduced bleeding, and minimally invasive anatomic liver resection (MIALR) is becoming popular gradually. Read More

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December 2021

Minimally invasive anatomic liver resection: results of a survey of world experts.

J Hepatobiliary Pancreat Sci 2021 Dec 6. Epub 2021 Dec 6.

HPB and Liver Transplant Unit, Clínica Universidad de Navarra, Pamplona, Spain.

Background: Although the number of minimally invasive liver resection (MILR) has been steadily increasing in many institutions, minimally invasive anatomic liver resection (MIALR) remains a complicated procedure that has not been standardized. We present the results of a survey among expert liver surgeons as a benchmark for standardizing MIALR.

Method: We administered this survey to 34 expert liver surgeons who routinely perform MIALR. Read More

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December 2021

Gene polymorphisms of SIRT1 in patients with rheumatoid arthritis.

Int J Rheum Dis 2021 Dec 5. Epub 2021 Dec 5.

Department of Rheumatology and Immunology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.

Aim: Previous studies have shown that silent information regulator 1 (SIRT1) expression is elevated in rheumatoid arthritis (RA) patients. However, whether gene polymorphisms in SIRT1 gene associated with RA in a Chinese Han population remains to be discussed.

Method: In this case-control study, 529 RA patients and 700 healthy controls were selected, and association of 11 SIRT1 gene polymorphisms (rs12415800, rs3740051, rs932658, rs3740053, rs7895833, rs10509291, rs33957861, rs7069102, rs2273773, rs3818292, rs1467568) with RA susceptibility was evaluated. Read More

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December 2021

Workplace Violence, Workforce Stability, and Well-being in China's Psychiatric Hospitals.

Am J Prev Med 2021 Dec 2. Epub 2021 Dec 2.

Vanke School of Public Health, Tsinghua University, Beijing, China. Electronic address:

Introduction: Workplace violence against psychiatric professionals is a growing problem, yet nationally representative data in China are lacking. This study examines workplace violence against psychiatrists and psychiatric nurses in China as well as its association with workforce stability and well-being .

Methods: Data came from a 2019 national survey of 14,264 participants (including 4,520 psychiatrists and 9,744 nurses) from 41 psychiatric hospitals across China. Read More

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December 2021

Tissue-specific distribution of primary and secondary metabolites of Baemoochae (×Brassicoraphanus) and its changes as a function of developmental stages.

Food Res Int 2021 12 2;150(Pt A):110796. Epub 2021 Nov 2.

Department of Food Science and Technology, Chung-Ang University, Anseong 17546, Republic of Korea. Electronic address:

The distribution and changes in the primary and secondary metabolite profiles of Baemoochae, an inter-generic hybrid of Chinese cabbage and radish, during the plant's developmental stages were investigated. Metabolites were analyzed using gas chromatography-mass spectrometry (GC-MS) and ultra-high-performance liquid chromatography-electrospray ionization-quadrupole time-of-flight (UHPLC-ESI-qTOF MS). Free sugar, organic acid, and amino acid composition depended on the tissue type and developmental stage of Baemoochae. Read More

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December 2021