51,326 results match your criteria children presenting


Factors associated with seizures at initial presentation in pediatric patients with cerebral arteriovenous malformations.

J Neurosurg Pediatr 2021 Sep 24:1-6. Epub 2021 Sep 24.

1Department of Neurological Surgery, University of California San Francisco, San Francisco.

Objective: Children with cerebral arteriovenous malformations (AVMs) can present with seizures, potentially increasing morbidity and impacting clinical management. However, the factors that lead to seizures as a presenting sign are not well defined. While AVM-related seizures have been described in case series, most studies have focused on adults and have included patients who developed seizures after an AVM rupture. Read More

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September 2021

Burkitt's lymphoma of medial part of clavicle: Case report of unusual localization.

Int J Surg Case Rep 2021 Sep 9;87:106393. Epub 2021 Sep 9.

ENT Department, Face and Neck Surgery, Military Hospital Mohammed V, Rabat, Morocco.

Introduction: Burkitt lymphoma is a form of non-Hodgkin's lymphoma in which cancer starts in immune cells called B-cells. Recognized as a fast-growing human tumor, it is considered as a medical emergency requiring immediate diagnostic and therapeutic intervention. However, intensive chemotherapy can achieve long-term survival in more than half the people with Burkitt lymphoma. Read More

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September 2021

Thoracoscopic segmentectomy for a large previously undiagnosed CPAM presenting as a spontaneous pneumothorax: A case report.

Int J Surg Case Rep 2021 Sep 15;87:106412. Epub 2021 Sep 15.

Division of Pediatric Surgery, Department of Surgery, Loma Linda University Children's Hospital, Loma Linda, CA, United States of America. Electronic address:

Introduction: Incidentally found congenital pulmonary airway malformations (CPAM) in older children are extremely rare and have traditionally been managed with minimally invasive versus open lobectomy of the affected lobe.

Presentation Of Case: In this report, we present a 11-year-old male who presented with a recurrent spontaneous pneumothorax and was found to have a large symptomatic CPAM confined to a single segment of the right lower lobe. The patient was successfully treated with thoracoscopic segmentectomy without any residual disease seen on follow up imaging. Read More

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September 2021

Atypical asthma in children who present with isolated chest tightness: risk factors and clinical features.

J Asthma 2021 Sep 24:1-9. Epub 2021 Sep 24.

Allergy Department, Capital Institute of Pediatrics, Beijing, China.

Objective: Asthmatic children presenting with chest tightness as the only symptom have not been widely recognized. This study attempted to find risk factors, summarize clinical features and offer some suggestions for the diagnosis of this atypical asthma. We studied 94 children, aged 6 to 14 years, who complained only of chest tightness. Read More

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September 2021

Pediatric onset lupus nephritis in western India-is it different from the rest of the country?

Lupus 2021 Sep 24:9612033211045069. Epub 2021 Sep 24.

Department of Pediatrics, 410730All India Institute of Medical Sciences Jodhpur, Jodhpur, Rajasthan.

Aim: To determine the clinicopathological characteristics and outcomes of children diagnosed with lupus nephritis in a tertiary hospital in western Rajasthan and compare it with the data available from other parts of India.

Material And Methods: A retrospective review of children presenting to a tertiary care center in western Rajasthan, India, with a diagnosis of pediatric Systemic Lupus Erythematosus (p SLE), between July 2017 and July 2020 was done. Comparisons of pediatric lupus in western India to other parts of country were done. Read More

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September 2021

Redback spider bites in children in South Australia: A 10-year review of antivenom effectiveness.

Emerg Med Australas 2021 Sep 23. Epub 2021 Sep 23.

Paediatric Emergency Department, Flinders Medical Centre, Adelaide, South Australia, Australia.

Objective: To describe the South Australian paediatric redback spider bite experience and to examine the hypothesis that redback antivenom (RBAV) treatment in children is clinically effective.

Methods: Retrospective chart review of all children under 18 years of age presenting to the EDs of the three major paediatric or mixed hospitals in Adelaide, South Australia, with a discharge diagnosis of redback spider envenomation between 1 January 2010 and 31 March 2020. The main outcome measures include: patient and bite demographics; presenting symptoms and signs; treatment provided; clinical effects at 2 h post RBAV administration on pain, diaphoresis, blood pressure, heart rate and systemic features; overall clinical impression of RBAV effectiveness and resolution of symptoms prior to discharge. Read More

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September 2021

Risk factors for recurrent positive results of the nucleic acid amplification test for COVID-19 patients: a retrospective study.

Hum Cell 2021 Sep 23. Epub 2021 Sep 23.

Department of Hepatic Surgery, The Eastern Hepatobiliary Surgery Hospital, Navy Medical University (Second Military Medical University), Yangpu Road 225, Shanghai, 200438, China.

Positive retests of COVID-19 represent a public health concern because of the increased risk of transmission. This study explored whether factors other than the nucleic acid amplification test (NAAT) contribute to positive retest results. Patients with COVID-19 admitted to the Guanggu district of the Hubei Maternal and Child Health Hospital between February 17 and March 28, 2020, were retrospectively included. Read More

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September 2021

Parental Views on the Non-Operative Management of Simple Appendicitis in Children: Results of a Cross-Sectional Survey.

World J Surg 2021 Sep 23. Epub 2021 Sep 23.

Departments of Paediatrics & Surgery, Faculty of Medicine, Nursing and Health Sciences, School of Clinical Sciences, Monash University, Melbourne, Australia.

Background: To determine parental attitudes for the non-operative management of simple appendicitis and determine willingness to participate in research evaluating different management options.

Method: Voluntary cross-sectional survey of parents/guardians presenting to paediatric outpatient department. Likert scale of 0-10 (strongly disagree-strongly agree) was utilised, analysis by individual question responses. Read More

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September 2021

A NICE combination for predicting hospitalisation at the Emergency Department: a European multicentre observational study of febrile children.

Lancet Reg Health Eur 2021 Sep 12;8:100173. Epub 2021 Jul 12.

Erasmus MC Sophia Children's Hospital, Department of General Paediatrics, P.O. Box 2060, 3000 CB, Rotterdam, the Netherlands.

Background: Prolonged Emergency Department (ED) stay causes crowding and negatively impacts quality of care. We developed and validated a prediction model for early identification of febrile children with a high risk of hospitalisation in order to improve ED flow.

Methods: The MOFICHE study prospectively collected data on febrile children (0-18 years) presenting to 12 European EDs. Read More

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September 2021

Osteochondroma Presenting Clinically with Carpal Tunnel Syndrome in a 12-Year-old Boy.

J Orthop Case Rep 2021 May;11(5):109-112

Department of Orthopaedics, D Y Patil University School of Medicine, Navi-Mumbai, Maharashtra. India.

Introduction: An exostosis is a benign growth of bone, which when capped with cartilage is called osteochondroma, which can appear as solitary or multiple, mostly affecting the long bones, pelvis, and shoulder region. The prevalence of known solitary exostosis is 1-2% in the general population. They are slow growing lesions with rare malignant transformation. Read More

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Paediatric haemoptysis from multiple pulmonary artery aneurysms.

Respirol Case Rep 2021 Oct 16;9(10):e0849. Epub 2021 Sep 16.

Division of Pulmonology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital Mahidol University Bangkok Thailand.

The case of multiple peripheral pulmonary artery aneurysms in children presenting with haemoptysis following an episode of bacterial endocarditis is presented. They are extremely rare and clinically non-specific but critical because early diagnosis is crucial for preventing sudden death from their rupture. Computed tomography pulmonary angiography remains the investigation of choice. Read More

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October 2021

Prevalence of Refractive Error and Visual Acuity Among School Children in the Plateau Region of Qinghai, China.

Int J Gen Med 2021 16;14:5795-5805. Epub 2021 Sep 16.

Shandong University of Traditional Chinese Medicine, Jinan, 250014, People's Republic of China.

Purpose: This study aimed to investigate the prevalence of refractive error and visual acuity among school children in the plateau region of Qinghai, China.

Methods: The school-based, cross-sectional study was performed in Menyuan, Qinghai, China. Three kindergartens and three primary schools were randomly enrolled from both rural areas and county towns. Read More

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September 2021

MHC class II in renal tubules plays an essential role in renal fibrosis.

Cell Mol Immunol 2021 Sep 23. Epub 2021 Sep 23.

National Clinical Research Center for Metabolic Diseases, Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, China.

Immunomodulation is considered a potential therapeutic approach for chronic kidney disease (CKD). Although it has been previously reported that CD4 T cells contribute to the development of renal fibrosis, the role of MHC class II (MHCII) in the development of renal fibrosis remains largely unknown. The present study reports that the expression of MHCII molecules in renal cortical tubules is upregulated in mouse renal fibrosis models generated by unilateral ureter obstruction (UUO) and folic acid (FA). Read More

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September 2021

COVID-19 Pediatric Dermatology.

Dermatol Clin 2021 Oct 31;39(4):505-519. Epub 2021 May 31.

Department of Dermatology, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Boston Children's Hospital, Boston, MA, USA. Electronic address:

Children are a unique subset of patients in relation to the COVID-19 pandemic, often presenting asymptomatically, mildly, or atypically. Manifestations of the skin may be a primary (or the only) presenting sign. Recognizing cutaneous manifestations of COVID-19 in the pediatric population is important to guiding precautions, testing, and management for patients and close contacts. Read More

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October 2021

Continuous Electroencephalogram and Antiseizure Medication Use in an International Pediatric Traumatic Brain Injury Population.

Neurocrit Care 2021 Sep 22. Epub 2021 Sep 22.

Medical College of Wisconsin, 9000 W. Wisconsin Ave, Milwaukee, WI, 53226, USA.

Background: Electrographic seizures are frequent and associated with worse outcomes following traumatic brain injury (TBI). Despite this, the use of continuous electroencephalogram (cEEG) remains low. Our study describes cEEG usage and treatment dosing antiseizure medications (ASMs) in an international pediatric TBI population, hypothesizing that children monitored with cEEG have an increased rate of treatment ASMs because of electrographic seizure detection, compared with children who are not monitored with cEEG. Read More

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September 2021

Magnetically Controlled Growing Rods for Early Scoliosis Treatment in Coffin-Siris Syndrome: Case Report and Literature Review.

Iowa Orthop J 2021 ;41(1):55-59

Department of Orthopaedic Surgery, Sapienza University of Rome, Rome, Italy.

Coffin-Siris Syndrome (CSS) is a rare, genetic syndrome characterized by multiple anomalies, including scoliosis. However, there are only a few reports about the management of scoliosis in these patients. We present the case of an 8-year-old female with CSS presenting with a progressive, rigid thoracolumbar kyphoscoliosis. Read More

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January 2021

C3 Glomerulopathy and Related Disorders in Children.

Clin J Am Soc Nephrol 2021 Sep 22. Epub 2021 Sep 22.

S Johnson, National Renal Complement Therapeutics Centre, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom of Great Britain and Northern Ireland.

: Membranoproliferative Glomerulonephritis (MPGN) and C3 Glomerulopathy are rare and overlapping disorders associated with dysregulation of the alternative complement pathway. Specific aetiological data for paediatric MPGN/C3 glomerulopathy are lacking, and outcome data are based upon retrospective studies without aetiological data. : Eighty prevalent pediatric patients with MPGN/C3 glomerulopathy underwent detailed phenotyping and long-term follow-up within the National Registry of Rare Kidney Diseases (RaDaR). Read More

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September 2021

Changes in Antibiotic Treatment for Children With Lyme Meningitis 2015-2020.

Hosp Pediatr 2021 Sep 22. Epub 2021 Sep 22.

Division of Emergency Medicine, Boston Children's Hospital, Boston, Massachusetts.

Objectives: Although ceftriaxone has been the first-line treatment of Lyme meningitis, the 2020 Infectious Disease Society of America, American College of Rheumatology, and American Academy of Neurology guideline recommends either doxycycline or ceftriaxone. Our objective was to explore recent trends in enteral antibiotic treatment of children with Lyme meningitis.

Methods: Using codes for case identification, we performed a multicenter retrospective study of patients ≤21 years of age presenting to a pediatric hospital contributing to the Pediatric Health Information System who were diagnosed with Lyme meningitis from 2015 to 2020. Read More

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September 2021

Freedom within a cage: how patriarchal gender norms limit women's use of mobile phones in rural central India.

BMJ Glob Health 2021 Sep;6(Suppl 5)

Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA.

Introduction: India has one of the highest gender gaps in mobile phone access in the world. As employment opportunities, health messaging (mHealth), access to government entitlements, banking, civic participation and social engagement increasingly take place in the digital sphere, this gender gap risks further exacerbating women's disadvantage in Indian society. This study identifies the factors driving women's unequal use of phones in rural Madhya Pradesh, India. Read More

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September 2021

First case of childhood Takayasu arteritis from Syria: a case report.

J Med Case Rep 2021 Sep 23;15(1):469. Epub 2021 Sep 23.

Division of Rheumatology, Department of Paediatrics, Children's University Hospital, Faculty of Medicine, Damascus University, Damascus, Syria.

Background: Takayasu arteritis is a systemic granulomatous inflammation affecting the large- and medium-sized vessels such as aorta, its main branches, and pulmonary and renal arteries. Childhood Takayasu arteritis is a subtype of Takayasu arteritis that affects the age group ranging from young infants to late adolescents.

Case Presentation: We report the first childhood Takayasu arteritis case from Syria, a 12-year-old Syrian girl presenting with nonspecific symptoms and signs plus ischemic clinical features in her left arm. Read More

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September 2021

Hepatocellular Carcinoma (HCC) in North-Western India: A Retrospective Study Focusing on Epidemiology, Risk Factors, and Survival.

J Gastrointest Cancer 2021 Sep 22. Epub 2021 Sep 22.

Department of Radiation Oncology, Sawai Man Singh Hospital, Jaipur, 302004, Rajasthan, India.

Background: Hepatocellular carcinoma (HCC) is an aggressive tumour with unpredictable outcome. It is fourth most common cause of cancers in India. However, information on HCC is inadequate in India. Read More

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September 2021

Acute Myeloid Leukemia Presenting as a Posterior Fossa Tumor.

J Pediatr Hematol Oncol 2021 Oct;43(7):277-278

Departments of Pediatrics and Child Health.

Extramedullary leukemia in pediatric acute myeloid leukemia can manifest as a myeloid sarcoma (MS), also known as granulocytic sarcoma or chloroma, in a variety of sites, or as leukemic blasts in the cerebrospinal fluid. Isolated MS of the central nervous system is rare. We report a case of acute myeloid leukemia with central nervous system-MS presenting as a posterior fossa mass mimicking a primary intracranial tumor. Read More

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October 2021

Designing an Indoor Air Quality Monitoring App for Asthma Management in Children: User-Centered Design Approach.

JMIR Form Res 2021 Sep 22;5(9):e27447. Epub 2021 Sep 22.

School of Communication and Information, Rutgers University, New Brunswick, NJ, United States.

Background: Indoor air pollution is a well-known risk factor that triggers and exacerbates asthma, the most common pediatric chronic disease. Using a mobile app to monitor indoor air quality could be promising in engaging children in keeping their indoor air quality clean and healthy as secondary environmental prevention for asthma management. However, no app is available to allow children to monitor, assess, and improve their indoor air quality. Read More

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September 2021

Kawasaki disease in adolescence and adulthood: Report of four cases.

J Dermatol 2021 Sep 22. Epub 2021 Sep 22.

Department of Dermatology, Asahikawa Medical University, Asahikawa, Japan.

Kawasaki disease (KD) in adolescence and adulthood is often underrecognized, because KD predominantly affects infants and young children below the age of 5 years. We report four cases of KD in patients 16-32 years of age. The first department that the patients visited was the Department of Otolaryngology, Obstetrics, or General Internal Medicine. Read More

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September 2021

Nasopharyngeal colonization of otopathogens in South Indian children with acute otitis media - A case control pilot study.

J Otol 2021 Oct 4;16(4):220-224. Epub 2021 Mar 4.

Department of ENT, Christian Medical College, Vellore, Tamil Nadu, India.

Background: Acute otitis media (AOM) is an inflammatory disease of the middle ear causing significant morbidity in early childhood. A pilot study was undertaken to identify the role of various risk factors South Indian children with AOM, especially the role of nasopharyngeal otopathogens.

Methodology: A prospective case control pilot study was conducted in children aged below six years, presenting to a single tertiary care from 2018 to 2019. Read More

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October 2021

Prevalence and risk factors for SARS-CoV-2 infection in children with and without symptoms seeking care in Managua, Nicaragua: results of a cross-sectional survey.

BMJ Open 2021 Sep 21;11(9):e051836. Epub 2021 Sep 21.

Mount Auburn Hospital, Cambridge, Massachusetts, USA.

Objective: This study aimed to capture key epidemiological data on SARS-CoV-2 infection in Nicaraguan children (≤18 years) seeking medical care, between 6 October and 16 November 2020.

Design: In this cross-sectional study, 418 children were recruited: 319 with symptoms characteristic of COVID-19 and 99 with no symptoms of illness. Children were tested for SARS-CoV-2 RNA using loop-mediated isothermal amplification. Read More

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September 2021

Is the NICE traffic light system fit-for-purpose for children presenting with undifferentiated acute illness in primary care?

Arch Dis Child 2021 Sep 21. Epub 2021 Sep 21.

Division of Population Medicine, Cardiff University, Cardiff, UK.

Background: The National Institute of Clinical Excellence (NICE) traffic light system uses children's symptoms and signs to categorise acute infections into red, amber and green. To our knowledge, no study has described the proportion of children with acute undifferentiated illness who fall into these categories in primary care, which is important since red and amber children are considered at higher risk of serious illness requiring urgent secondary care assessment.

Aim: To estimate the proportion of acutely unwell children presenting to primary care classified by the NICE traffic light system as red, amber or green, and to describe their initial management. Read More

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September 2021

Encephalitis patient-derived monoclonal GABAA receptor antibodies cause epileptic seizures.

J Exp Med 2021 Nov 21;218(11). Epub 2021 Sep 21.

German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany.

Autoantibodies targeting the GABAA receptor (GABAAR) hallmark an autoimmune encephalitis presenting with frequent seizures and psychomotor abnormalities. Their pathogenic role is still not well-defined, given the common overlap with further autoantibodies and the lack of patient-derived mAbs. Five GABAAR mAbs from cerebrospinal fluid cells bound to various epitopes involving the α1 and γ2 receptor subunits, with variable binding strength and partial competition. Read More

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November 2021

The effect of COVID-19 on children with congenital talipes equinovarus in a tertiary service in the United Kingdom.

J Pediatr Orthop B 2021 Sep 17. Epub 2021 Sep 17.

Department of Orthopaedic Surgery, Bart's Health NHS Trust Department of Orthopaedics, Barts and the London School of Medicine and Dentistry, London, UK.

During the coronavirus disease 2019 (COVID-19) pandemic, many aspects of healthcare have been hindered. The primary aim of this study was to identify what the impact of COVID-19 was on the delivery of outpatient care for children with congenital talipes equinovarus deformity (CTEV) at a large tertiary hospital in the UK. This study reviewed the patients who commenced their Ponseti treatment between March and September 2020, representing the cohort who received hands-on care during the first wave of the COVID-19 pandemic. Read More

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September 2021

Brain low-grade gliomas with high-grade spinal localization. Report of a clinical case and systematic literature review.

J Neurosurg Sci 2021 Sep 21. Epub 2021 Sep 21.

Department of Neurosurgery, Department of Neuroscience, Psychology, Drug Area and Child Health (NEUROFARBA), Careggi University Hospital, University of Florence, Florence, Italy.

Introduction: Oncological aggressiveness and the ability to present distant localizations are known in high-grade gliomas (HGGs), but the knowledge about the possible aggressiveness of LGGs is scarce, especially concerning possible spinal localization.

Evidence Acquisition: A systematic search of LGGs with spinal localization on the three primary online databases (PubMed/MEDLINE, Embase, and Cochrane) was conducted. We included adult patients with histological diagnosis of intracranial LGG and specified WHO grade showing a remote spinal localization during follow-up. Read More

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September 2021