15,689 results match your criteria childhood purpose

Menarche characteristics in association with total and cause-specific mortality: a prospective cohort study of Mexican teachers.

Ann Epidemiol 2021 Jun 21. Epub 2021 Jun 21.

Center for Research on Population Health, National Institute of Public Health, Mexico City, Mexico; Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, United States.

Purpose: We evaluated the relation between age at menarche and time to menstrual regularity with all-cause and cause specific mortality in a cohort of Mexican women.

Methods: We followed 113,540 women from the Mexican Teachers' Cohort. After a mean follow-up time of 9. Read More

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Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium.

J Clin Oncol 2021 Jun 24:JCO2003060. Epub 2021 Jun 24.

Department of Pediatrics, Seattle Children's Hospital, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA.

Purpose: Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood. Despite aggressive therapy, the 5-year survival rate for patients with metastatic or recurrent disease remains poor, and beyond fusion status, no genomic markers are available for risk stratification. We present an international consortium study designed to determine the incidence of driver mutations and their association with clinical outcome. Read More

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An update of the aetiological factors involved in molar incisor hypomineralisation (MIH): a systematic review and meta-analysis.

Eur Arch Paediatr Dent 2021 Jun 24. Epub 2021 Jun 24.

Private Paediatric Dental Clinic, 2 Papadiamantopoulou Street, 11528, Athens, Greece.

Purpose: To systematically review the aetiological factors associated with molar incisor hypomineralisation (MIH). To this day, the aetiology remains unknown. Determining risk factors would allow risk assessment and enhance early diagnosis of MIH in young patients. Read More

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The impact of childhood diagnosed ADHD versus controls without ADHD diagnoses on later labour market attachment-a systematic review of longitudinal studies.

Child Adolesc Psychiatry Ment Health 2021 Jun 23;15(1):34. Epub 2021 Jun 23.

Center for Social Medicine, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.

Previous studies have suggested that Attention Deficit Hyperactive Disorder (ADHD) affect individuals across their lifespan, especially in relation to employment. The purpose of this review was to synthesize the results from studies examining the prospective association of ADHD diagnosis in childhood and later education, earnings and employment, compared to children without an ADHD diagnosis. A review protocol was prospectively registered with PROSPERO (ID = CRD42019131634). Read More

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Screening for distress and needs: Findings from a multinational validation of the Adolescent and Young Adult Psycho-Oncology Screening Tool with newly diagnosed patients.

Psychooncology 2021 Jun 23. Epub 2021 Jun 23.

Division of Oncology, Leeds Institute of Medical Research, School of Medicine, The University of Leeds, UK.

Objective: Adolescents and young adults (AYAs) diagnosed with cancer commonly experience elevated psychological distress and need appropriate detection and management of the psychosocial impact of their illness and treatment. This paper describes the multinational validation of the Distress Thermometer (DT) for AYAs recently diagnosed with cancer and the relationship between distress and patient concerns on the AYA-Needs Assessment (AYA-NA).

Methods: AYA patients (N=288; 15-29 years, M =21. Read More

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Evaluation of Parent-Researcher Agreement on the Vocal Development Landmarks Interview.

J Speech Lang Hear Res 2021 Jun 22:1-14. Epub 2021 Jun 22.

Center for Childhood Deafness, Language and Learning, Boys Town National Research Hospital, Omaha, NE.

Purpose Parent report was compared to judgments made by a trained researcher to determine the utility of the Vocal Development Landmarks Interview (VDLI) for monitoring development of vocal behaviors in very young children. Method Parents of 40 typically developing children, ages 6-21 months, provided full-day naturalistic audio recordings of their children's vocalizations after completing the VDLI. Six 5-min segments of highly voluble periods were selected from each recording and were analyzed, coded, and scored by the researcher. Read More

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Multichamber Dysfunction in Children and Adolescents With Severe Obesity: A Cardiac Magnetic Resonance Imaging Myocardial Strain Study.

J Magn Reson Imaging 2021 Jun 21. Epub 2021 Jun 21.

Laboratoire d'Imagerie Biomédicale, Sorbonne Université, INSERM, CNRS, Paris, France.

Background: In severe obesity, left ventricular (LV) and right ventricular (RV) remodeling and contractile dysfunction have been documented, but less is known regarding left atrial (LA) dysfunction and its association with LV/RV remodeling, especially in children.

Purpose: To assess the effects of severe childhood obesity on cardiac function by using multichamber strain analysis with MRI.

Study Type: Prospective. Read More

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Food Insecurity and Cardiometabolic Conditions: a Review of Recent Research.

Curr Nutr Rep 2021 Jun 21. Epub 2021 Jun 21.

Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Purpose Of Review: To understand recent literature that examines associations between food insecurity and cardiometabolic conditions and risk factors. We included original research, systematic reviews, and meta-analyses on the topic of food insecurity and cardiometabolic risk published from January 1, 2017, to December 31, 2020. Editorials, perspectives, and case reports were excluded. Read More

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DMFT of the First Permanent Molars, dmft and Related Factors among All First-Grade Primary School Students in Rafsanjan Urban Area.

J Dent (Shiraz) 2021 Jun;22(2):109-117

Dept. of Biostatistics, Rajaie Cardiovascular Medical and research center, Iran University of Medical Science, Tehran, Iran.

Statement Of The Problem: Dental caries is the most common chronic childhood disorders throughout the world. The dmft (decayed, missing, and filled primary teeth) and DMFT (decayed, missing, and filled permanent teeth) are some of the most important epidemiological indices in dentistry. Evaluation of these two indicators in the population can help in future planning of healthcare programs to improve oral health status. Read More

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Applying the Social Development Model in Middle Childhood to Promote Healthy Development: Effects From Primary School Through the 30s and Across Generations.

J Dev Life Course Criminol 2021 Mar 17;7(1):66-86. Epub 2020 Sep 17.

University of Cambridge, England.

Purpose: This paper describes the origins and application of a theory, the social development model (SDM), that seeks to explain causal processes that lead to the development of prosocial and problem behaviors. The SDM was used to guide the development of a multicomponent intervention in middle childhood called Raising Healthy Children (RHC) that seeks to promote prosocial development and prevent problem behaviors. This paper reviews and integrates the tests of the SDM and the impact of RHC. Read More

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Analysis of the self-compassion and cognitive flexibility with marital compatibility in parents of children with autism spectrum disorder.

Int J Dev Disabil 2019 Mar 1;66(4):282-288. Epub 2019 Mar 1.

Department of Psychology, Isfahan (Naein) Branch, Islamic Azad University, Isfahan, Iran.

: Parents of children with autism spectrum disorder (ASD) face many problems in their marital lives. Autism is a developmental disorder, emerging during childhood that affects development across various domains. Studies suggest that autism prevalence rates are increasing, and research shows that parents of children with ASD frequently experience high levels of parenting stress. Read More

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The incidence of distal radius fractures in a Swedish pediatric population - an observational cohort study of 90 970 individual fractures.

BMC Musculoskelet Disord 2021 Jun 19;22(1):564. Epub 2021 Jun 19.

Department of Clinical Science and Education, Södersjukhuset Karolinska Institutet, SE-118 83, Stockholm, Sweden.

Background: 40-50 % of all boys and 30-40 % of girls suffer from at least one fracture during childhood. A quarter of these fractures affects the wrist, making it the worst affected part of the body. Children often sustain the injury during play or sport activities. Read More

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Multi-purpose cash transfers and health among vulnerable Syrian refugees in Lebanon: a prospective cohort study.

BMC Public Health 2021 Jun 19;21(1):1176. Epub 2021 Jun 19.

Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street Suite E8132, Baltimore, MD, 21205, USA.

Background: Multipurpose cash transfers (MPCs) are used on a widespread basis in the Syrian refugee response; however, there is little to no evidence as to how they affect health in humanitarian crises.

Methods: A prospective cohort study was conducted from May 2018 through July 2019 to evaluate the impact of MPCs on health care-seeking and expenditures for child, adult acute, and adult chronic illness by Syrian refugees in Lebanon. Households receiving MPCs from UNHCR were compared to control households not receiving UNHCR MPCs. Read More

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Part 2: When Should Bisphosphonates Be Used in Children with Chronic Illness Osteoporosis?

Leanne M Ward

Curr Osteoporos Rep 2021 Jun 19. Epub 2021 Jun 19.

University of Ottawa, Ottawa, Canada.

Purpose Of Review: Part 1 of this review on secondary osteoporosis of childhood was devoted to understanding which children should undergo bone health monitoring, when to label a child with osteoporosis in this setting, and how best to monitor in order to identify early, rather than late, signs of bone fragility. In Part 2 of this review, we discuss the next critical step in deciding which children require bisphosphonate therapy. This involves distinguishing which children have the potential to undergo "medication-unassisted" recovery from secondary osteoporosis, obviating the need for bisphosphonate administration, from those who require anti-resorptive therapy in order to recover from osteoporosis. Read More

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Factors Influencing Resilience among Korean adolescents and young adult survivors of childhood cancer.

Eur J Oncol Nurs 2021 May 7;53:101977. Epub 2021 May 7.

College of Nursing, Mo-Im Kim Nursing Research Institute, Yonsei University, Seoul, South Korea. Electronic address:

Purpose: The number of childhood cancer survivors has been steadily increasing because of improved cancer treatment outcomes. We aimed to examine the level of cancer stigma, coping, spirituality, hope, family communication, social support and resilience in adolescent and adult childhood cancer survivors and identify factors associated with resilience.

Method: This study is a descriptive survey conducted on 139 childhood cancer survivors aged 15-29 years who had been diagnosed with cancer prior to the age of 19 years at a general hospital in Seoul. Read More

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Distress, anxiety, depression and unmet needs in thyroid cancer survivors: a longitudinal study.

Endocrine 2021 Jun 18. Epub 2021 Jun 18.

Clinical Psychology Unit, Department of Neuroscience, University of Turin, "Città della Salute e della Scienza" Hospital of Turin, Turin, Italy.

Purpose: Despite a good prognosis, thyroid cancer (TC) survivors often report psychological distress and decreased quality of life. This longitudinal study aims to evaluate TC survivors' levels of distress, anxiety, depression and unmet needs, checking potential life events.

Methods: Distress Thermometer, Hospital Anxiety Depression Scale, Supportive Care Need Survey (short form) and Interview for Recent Life Events were administered to 73 TC survivors (T0) and 44 of them were re-tested one year later (T1). Read More

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Benign longitudinal T2-hyperintense signal in the lateral cord in infancy: a cross-sectional study of spinal cord white matter maturation on magnetic resonance imaging.

Pediatr Radiol 2021 Jun 18. Epub 2021 Jun 18.

Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Background: Longitudinal T2-hyperintense signal is commonly seen in the spinal cord of infants and likely reflects normal unmyelinated white matter tracts, but it can be mistaken for pathology. Autopsy studies have described incomplete myelination of spinal cord in early childhood; however, the maturation timeline of the spinal cord has not been described on imaging.

Objective: The purpose of this study was to retrospectively evaluate the maturation timeline of the spinal cord on MRI to provide a baseline for image interpretation. Read More

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The single-point insulin sensitivity estimator (SPISE) index is a strong predictor of abnormal glucose metabolism in overweight/obese children: a long-term follow-up study.

J Endocrinol Invest 2021 Jun 17. Epub 2021 Jun 17.

Department of Clinical Medicine, Public Health, Life and Environmental Sciences (MeSVA), University of L'Aquila, L'Aquila, Italy.

Purpose: To investigate the relationship between the single-point insulin sensitivity estimator (SPISE) index, an insulin sensitivity indicator validated in adolescents and adults, and metabolic profile in overweight/obese children, and to evaluate whether basal SPISE is predictive of impaired glucose regulation (IGR) development later in life.

Methods: The SPISE index (= 600 × HDL/Triglycerides × BMI) was calculated in 909 overweight/obese children undergoing metabolic evaluations at University of Cagliari, Italy, and in 99 normal-weight, age-, sex-comparable children, selected as a reference group, together with other insulin-derived indicators of insulin sensitivity/resistance. 200 overweight/obese children were followed-up for 6. Read More

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Adverse Childhood Experiences and Past 30-Day Cigarette and E-Cigarette Use Among Sexual and Gender Minority College Students.

LGBT Health 2021 Jun 15. Epub 2021 Jun 15.

Department of Health Sciences, California State University, Northridge, Northridge, California, USA.

Sexual and gender minority (SGM) young adults report disproportionately higher rates of tobacco and nicotine product use. This study assessed the role of adverse childhood experiences (ACEs) in nicotine and tobacco product use among SGM young adults. A cross-sectional survey was administered to 11,694 college students (ages 18-29 years) between 2017 and 2018 in California, Minnesota, and Texas. Read More

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Children's measured exposure to food and beverage advertising on television in Toronto (Canada), May 2011-May 2019.

Can J Public Health 2021 Jun 15. Epub 2021 Jun 15.

School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, 600 Peter Morand Crescent, Ottawa, Ontario, K1G 5Z3, Canada.

Objective: Exposure to unhealthy food advertising is a known determinant of children's poor dietary behaviours. The purpose of this study was to quantify and characterize Canadian children's exposure to food advertising on broadcast television and examine trends over time.

Methods: Objectively measured advertising exposure data for 19 food categories airing on 30 stations broadcast in Toronto were licenced for May 2011 and May 2019. Read More

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An overview of the mental and physical health status and post-migration psychosocial stressors of refugee toddlers and preschoolers.

J Child Adolesc Psychiatr Nurs 2021 Jun 14. Epub 2021 Jun 14.

Department of Child and Adolescent Psychiatry, Medical Faculty, Marmara University, Istanbul, Turkey.

Purpose: Although thousands of refugee children are being born in resettlement areas, few studies have described the mental and physical status in early childhood. We aimed to study the mental, physical status, and post-migration psychosocial stressors of refugee toddlers and preschoolers.

Design And Methods: The Diagnostic Classification of Mental Health and Developmental Disorders of Infancy and Early Childhood was used to assess psychiatric disorders, parent-child relational context, physical health conditions, psychosocial and environmental stressors, and developmental competencies of children who were evaluated at the clinic site. Read More

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Challenges in Patients with Trisomy 21: A Review of Current Knowledge and Recommendations.

J Ophthalmol 2021 26;2021:8870680. Epub 2021 May 26.

Department of Ophthalmology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Purpose: To summarize and review the common ophthalmic anomalies in children with trisomy 21 (Down syndrome) in order to propose an update to current clinical recommendations.

Methods: A retrospective chart review, systemic literature review, and international survey of the frequency of ocular abnormalities, screening schedules, and challenging aspects examining children with trisomy 21. The chart review included patients treated at the Department of Ophthalmology at the University Hospital of Zurich over a two-year period. Read More

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Prevalence of Early Childhood Caries in Southern Italy: An Epidemiological Study.

Int J Dent 2021 25;2021:5106473. Epub 2021 May 25.

Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, Via S. Sofia 78, Catania 95124, Italy.

The purpose of this study was to assess the prevalence of Early Childhood Caries (ECC) and oral habits among preschool children from a southern Italian cohort. The survey population consisted of 300 subjects randomly selected among children attending two kindergartens in Catania, Italy. The prevalence of ECC and oral habits were clinically evaluated. Read More

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Is sexual trauma a risk factor for functional (psychogenic) seizures?

Neurosci Biobehav Rev 2021 Jun 11;128:58-63. Epub 2021 Jun 11.

Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

The relationship between functional seizures (FS) and sexual trauma has received attention in many previous studies. However, the mechanisms underlying this relationship have not been elucidated yet. The purpose of this narrative review is to explore and speculate on the underpinning neurobiological mechanisms for the association and link between sexual trauma and functional seizures. Read More

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Charting mandatory childhood vaccination policies worldwide.

Vaccine 2021 Jun 10. Epub 2021 Jun 10.

Oxford Vaccine Group and Oxford Martin School, University of Oxford, Centre for Clinical Vaccinology and Tropical Medicine (CCVTM), Old Road, Oxford OX3 7LE, United Kingdom.

Mandatory childhood vaccination is becoming an increasingly important policy intervention for governments trying to address low vaccination rates. Mandates require vaccination for a certain purpose, most commonly related to school entry for children. However, the discussion surrounding the extent and impact of mandatory vaccination programmes for babies and children have largely been limited to high-income countries. Read More

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Influence of maternal postpartum depression on children's toothbrushing frequency.

Community Dent Oral Epidemiol 2021 Jun 11. Epub 2021 Jun 11.

Department of Orthodontics and Speech Therapy for Craniofacial Anomalies, Tohoku University Hospital, Sendai, Japan.

Objectives: Daily toothbrushing behaviour is very effective for the prevention of early childhood dental caries (ECC), but is mostly dependent upon parental management. Intrapersonal association between lower toothbrushing frequency and depression is well known; however, the impact of maternal postpartum depression on child toothbrushing behaviour within the mother-child dyad remains unknown. The aim of this study was to determine the association between the prevalence of maternal postpartum depression and lower toothbrushing frequency in children aged two years. Read More

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Oral health of overweight and obese children and adolescents: a comparative study with a multivariate analysis of risk indicators.

Eur Arch Paediatr Dent 2021 Jun 11. Epub 2021 Jun 11.

First Department of Pediatrics, Medical School, Aghia Sophia Children's Hospital, National and Kapodistrian University of Athens, 1 Thivon Str, Goudi, 11527, Athens, Greece.

Purpose: The aim of this study was to investigate the oral health status of overweight and obese children compared to normal weight children and to explore the effect of risk indicators, including stress, on the oral health of the children.

Methods: For this cross-sectional study, 7-15-year-old children were enrolled: divided into a group of overweight and obese and a group of normal weight children. Parent-reported questionnaires were used to for data collection demographic data, children's medical and developmental history, brushing frequency and dietary habits. Read More

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Voluntary COVID-19 vaccination of children: a social responsibility.

J Med Ethics 2021 Jun 11. Epub 2021 Jun 11.

Bioethics and Law Initiative, Tel Aviv University Faculty of Medicine, Tel Aviv, Israel

Nearly 400 million adults have been vaccinated against COVID-19. Children have been excluded from the vaccination programmes owing to their lower vulnerability to COVID-19 and to the special protections that apply to children's exposure to new biological products. WHO guidelines and national laws focus on medical safety in the process of vaccine approval, and on national security in the process of emergency authorisation. Read More

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Frequency and Prognostic Impact of Amplifications and Mutations in the European Neuroblastoma Study Group (SIOPEN) High-Risk Neuroblastoma Trial (HR-NBL1).

J Clin Oncol 2021 Jun 11:JCO2100086. Epub 2021 Jun 11.

Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

Purpose: In neuroblastoma (NB), the ALK receptor tyrosine kinase can be constitutively activated through activating point mutations or genomic amplification. We studied genetic alterations in high-risk (HR) patients on the HR-NBL1/SIOPEN trial to determine their frequency, correlation with clinical parameters, and prognostic impact.

Materials And Methods: Diagnostic tumor samples were available from 1,092 HR-NBL1/SIOPEN patients to determine amplification status (n = 330), mutational profile (n = 191), or both (n = 571). Read More

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Characteristics of Patients ≥ 10 Years of Age with Diffuse Intrinsic Pontine Glioma: A Report from the International DIPG Registry.

Neuro Oncol 2021 Jun 11. Epub 2021 Jun 11.

The Ohio State University College of Medicine, Columbus, OH.

Background: DIPG generally occurs in young school-age children, although can occur in adolescents and young adults. The purpose of this study was to describe clinical, radiological, pathologic, and molecular characteristics in patients ≥10 years of age with DIPG enrolled in the International DIPG Registry (IDIPGR).

Methods: Patients ≥10 years of age at diagnosis enrolled in the IDIPGR with imaging confirmed DIPG diagnosis were included. Read More

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