33,991 results match your criteria childhood obesity

Interventions to Treat Obesity in Mexican Children and Adolescents: Systematic Review and Meta-Analysis.

Nutr Rev 2021 Aug 2. Epub 2021 Aug 2.

School of Computing, Robert Gordon University, Aberdeen, United Kingdom.

Context: Prevalence of overweight and obesity has been rising in the past 3 decades among Mexican children and adolescents.

Objective: To systematically review experimental studies evaluating interventions to treat obesity in Mexican children and adolescents (≤18 years old).

Data Sources: For this study, 13 databases and 1 search engine were searched. Read More

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Pediatric BMI changes during COVID-19 pandemic: An electronic health record-based retrospective cohort study.

EClinicalMedicine 2021 Aug 16;38:101026. Epub 2021 Jul 16.

Center for Observational Research, Amgen, Inc., 1000 E Oaks Blvd, One Amgen Ctr. Dr. M/S 24-1-C, Thousand Oaks, California 91362, United States.

Background: Beginning March 2020, the COVID-19 pandemic has disrupted different aspects of life. The impact on children's rate of weight gain has not been analysed.

Methods: In this retrospective cohort study, we used United States (US) Electronic Health Record (EHR) data from Optum® to calculate the age- and sex- adjusted change in BMI (∆BMI) in individual 6-to-17-year-old children between two well child checks (WCCs). Read More

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Effect of Mobile Health Technology on Weight Control in Adolescents and Preteens: A Systematic Review and Meta-Analysis.

Front Public Health 2021 15;9:708321. Epub 2021 Jul 15.

Department of Business Administration, Cheng Shiu University, Kaohsiung, Taiwan.

Childhood obesity is a crucial public health concern. In recent years, numerous studies have employed mobile health technology applications for weight control in children but obtaining varying effects. We conducted a meta-analysis to discuss the effectiveness of mobile health technology in reducing the body mass index (BMI) of obese children. Read More

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Making Childhood Obesity a Priority: A Qualitative Study of Healthcare Professionals' Perspectives on Facilitating Communication and Improving Treatment.

Front Public Health 2021 15;9:652491. Epub 2021 Jul 15.

Department of Microscopic Morphology Genetics Discipline, Center of Genomic Medicine, Regional Center of Medical Genetics Timis, "Victor Babes" University of Medicine and Pharmacy Timisoara, Timisoara, Romania.

In Romania, one in four children has excess weight. Because childhood obesity is a sensitive topic, many healthcare professionals find it difficult to discuss children's excess weight with parents. This study aims to identify barriers and facilitators in childhood obesity-related communication, as perceived by healthcare professionals in Romania. Read More

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Effectiveness and safety of interventions to manage childhood overweight and obesity: An Overview of Cochrane systematic reviews.

Paediatr Child Health 2021 Aug 20;26(5):310-316. Epub 2020 Aug 20.

Alberta Research Centre for Health Evidence, Department of Pediatrics, University of Alberta, Edmonton, Alberta.

Background: Childhood overweight and obesity are associated with adverse physical, social, and psychological outcomes.

Objectives: We conducted an overview of Cochrane systematic reviews on the effectiveness and risks of interventions to treat overweight and obesity in children and adolescents.

Methods: In June 2019, we searched the Cochrane Database of Systematic Reviews for eligible reviews. Read More

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Human Beta Cell Regenerative Drug Therapy for Diabetes: Past Achievements and Future Challenges.

Front Endocrinol (Lausanne) 2021 16;12:671946. Epub 2021 Jul 16.

The Diabetes Obesity Metabolism Institute, The Icahn School of Medicine at Mount Sinai, New York, NY, United States.

A quantitative deficiency of normally functioning insulin-producing pancreatic beta cells is a major contributor to all common forms of diabetes. This is the underlying premise for attempts to replace beta cells in people with diabetes by pancreas transplantation, pancreatic islet transplantation, and transplantation of beta cells or pancreatic islets derived from human stem cells. While progress is rapid and impressive in the beta cell replacement field, these approaches are expensive, and for transplant approaches, limited by donor organ availability. Read More

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Altered cardiometabolic profile in girls with central precocious puberty and adipokines: A propensity score matching analysis.

Cytokine 2021 Jul 29:155660. Epub 2021 Jul 29.

Department of Pediatric Endocrinology, Children's Hospital, National Medical Center XXI Century, Instituto Mexicano del Seguro Social, Av. Cuauhtemoc 330, Col. Doctores, C.P. 06720 México City, Mexico. Electronic address:

Objective: To compare cardiometabolic factors and adipokines between patients with recently diagnosed CPP and controls without CPP, paired by BMI Z scores (BMIz) and classified into girls with adequate nutritional status and girls who are overweight or obese.

Methods: This cross-sectional study was performed from January 2012 to May 2015 at two tertiary care pediatric centers in Mexico City. We included female patients with idiopathic CPP without other chronic pathology and healthy controls. Read More

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Cardiorespiratory Fitness in Children with Overweight-Obesity: Insights into the Molecular Mechanisms.

Scand J Med Sci Sports 2021 Aug 1. Epub 2021 Aug 1.

PROFITH "PROmoting FITness and Health Through Physical Activity" Research Group, Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, 18011, Granada, Spain.

Objectives: High cardiorespiratory fitness (CRF) levels reduce the risk of developing cardiovascular disease (CVD) during adulthood. However, little is known about the molecular mechanisms underlying the health benefits of high CRF levels at the early stage of life. This study aimed to analyze the whole-blood transcriptome profile of fit children with overweight/obesity (OW/OB) compared to unfit children with OW/OB. Read More

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Inflammation in Obese Children and Adolescents: Association with Psychosocial Stress Variables and Effects of a Lifestyle Intervention.

Brain Behav Immun 2021 Jul 29. Epub 2021 Jul 29.

Department of Developmental, Personality and Social Psychology, Ghent University, H. Dunantlaan 2, 9000 Ghent, Belgium.

Obesity in childhood and adolescence is a complex health issue that has detrimental effects on the physical and psychological health of the youngster, both in the short and long term. A characteristic of obesity is the associated chronic low-grade inflammation which can result in insulin resistance. Previous research suggested that biomarkers referring to such increased inflammation may help in understanding resistance to weight loss. Read More

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Associations between exposure to polycyclic aromatic hydrocarbons and metabolic syndrome in U.S. adolescents: Cross-sectional results from the National Health and Nutrition Examination Survey (2003-2016) data.

Environ Res 2021 Jul 29:111747. Epub 2021 Jul 29.

Center for Endocrine Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, 101149, China; Beijing Key Laboratory of Diabetes Research and Care, Beijing, 101149, China. Electronic address:

Background: The metabolic syndrome is a constellation of risk factors, including abdominal obesity, hypertension, dyslipidemia, and hyperglycemia. Polycyclic aromatic hydrocarbons (PAHs) constitute a group of chemicals that are formed during the incomplete combustion of coal, oil and gas, garbage, and other organic substances. In the occupational exposure population, PAHs exposure increased the prevalence ratio of metabolic syndrome. Read More

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Glucose levels show independent and dose-dependent association with worsening acute pancreatitis outcomes: Post-hoc analysis of a prospective, international cohort of 2250 acute pancreatitis cases.

Pancreatology 2021 Jun 22. Epub 2021 Jun 22.

Institute for Translational Medicine, Szentágothai Research Centre, Medical School, University of Pécs, Pécs, Hungary; Doctoral School of Clinical Medicine, University of Szeged, Szeged, Hungary; Centre for Translational Medicine, Department of Medicine, University of Szeged, Szeged, Hungary.

Background: Metabolic risk factors, such as obesity, hypertension, and hyperlipidemia are independent risk factors for the development of various complications in acute pancreatitis (AP). Hypertriglyceridemia dose-dependently elicits pancreatotoxicity and worsens the outcomes of AP. The role of hyperglycemia, as a toxic metabolic factor in the clinical course of AP, has not been examined yet. Read More

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What Are the Updates on Epidemiology of Progressive Collapsing Foot Deformity?

Foot Ankle Clin 2021 Sep 27;26(3):407-415. Epub 2021 Jun 27.

Hospital San José, Santiago, Chile; Clinica Universidad de los Andes, Avenida Plaza 2501, Las Condes, Santiago 7620157, Chile.

Progressive collapsing foot deformity is one of the most controversial topics in foot and ankle surgery. Much research has been done regarding anatomy, biomechanics, and etiology behind this complex deformity and there is interest in studying metabolic or genetic conditions that could influence the development of this multifactorial disorder. Relevant anatomy includes osseous and soft tissue structures. Read More

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September 2021

Area-level and family-level socioeconomic position and body composition trajectories: longitudinal analysis of the UK Millennium Cohort Study.

Lancet Public Health 2021 Aug;6(8):e598-e607

Social Research Institute, Institute of Education, University College London, London, UK.

Background: Inequalities in the trajectories of body composition in childhood and adolescence have been infrequently studied. Despite the importance of environmental factors in obesity development, little research has looked at area-level socioeconomic position, independent of family socioeconomic position. We aimed to assess how inequalities in body composition develop with age. Read More

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Association of the apoptotic marker APO1/Fas with children's predisposing factors for metabolic syndrome and with mean platelet volume.

J Pediatr Endocrinol Metab 2021 Aug 2. Epub 2021 Aug 2.

Laboratory of Biology and Biochemistry, Faculty of Health Sciences, Department of Nursing, University of Peloponnese, Tripoli, Greece.

Background: Apoptosis antigen 1/FAS receptor (APO1/Fas) signaling in endothelial cells plays a significant role in angiogenesis while increased mean platelet volume (MPV) is an important marker for platelet activation. We investigated the possible correlation between APO1/Fas and both metabolic parameters and platelet activity (indicated by the MPV) in a healthy pediatric population.

Methods: One hundred and eighty-five children, aged 5-17 years old, were enrolled in the study. Read More

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Bariatric interventions in craniopharyngioma patients - Best choice or last option for treatment of hypothalamic obesity?

J Clin Endocrinol Metab 2021 Jul 31. Epub 2021 Jul 31.

University Children's Hospital, Department of Pediatrics and Pediatric Hematology/Oncology, Klinikum Oldenburg AöR, Carl von Ossietzky University, 26133 Oldenburg, Germany.

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Continuous flow left ventricular assist devices do not worsen endothelial function in subjects with chronic heart failure: a pilot study.

ESC Heart Fail 2021 Jul 31. Epub 2021 Jul 31.

Department of Biomedical Sciences and Human Oncology, Pediatric Section, University "A. Moro" of Bari, Bari, Italy.

Aims: To evaluate endothelial function in subjects with left ventricular assist devices (LVADs), comparing them with subjects with chronic heart failure with reduced ejection fraction on the list for heart transplant (HT) and with HT patients with a normal systolic cardiac function to identify any differences.

Methods: We enrolled 28 subjects with LVAD, 55 subjects with HT, and 42 subjects with heart failure on the transplant list. The subjects underwent a general physical examination, assessment of laboratory blood parameters, and assessment of endothelial function through flow-mediated dilation (FMD) of brachial artery. Read More

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Hypertension and Pre-Hypertension among Children and Adolescents in Port Harcourt, Nigeria.

West Afr J Med 2021 Jul;38(7):661-666

Department of Pediatrics, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.

Background: Hypertension is a major cause of morbidity and mortality and has been found to track from childhood to adulthood with long term cardiovascular and renal complications. Hence early detection and control in children and adolescents is crucial. This study was conceived to add to the body of evidence on the blood pressure pattern; the prevalence of pre-hypertension and hypertension among primary and secondary school children in Port Harcourt, Rivers State, Nigeria. Read More

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Equitable approaches to reducing the prevalence of pediatric obesity: school nutrition policies and beyond.

Int J Obes (Lond) 2021 Jul 30. Epub 2021 Jul 30.

Department of Pediatrics, Yale School of Medicine, New Haven, CT, USA.

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Quality of life of children and adolescents with clinical obesity, perspectives of children and parents.

Obes Res Clin Pract 2021 Jul 28. Epub 2021 Jul 28.

Department of Pediatrics, Hospital Gelderse Vallei, P.O. Box 9025, Ede, 6710 HN, The Netherlands. Electronic address:

Background/objectives: Childhood obesity can have important psychological impacts. The objective of this study was to evaluate the Health Related Quality of Life (HRQoL) of children and adolescents with overweight and obesity. The participants were referred to an outpatient hospital-based obesity treatment. Read More

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New bioelectrical impedance analysis equations for children and adolescents based on the deuterium dilution technique.

Clin Nutr ESPEN 2021 Aug 24;44:402-409. Epub 2021 May 24.

School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia.

Background And Aims: Body composition in childhood is not only a marker of the prevalence of obesity, but it can also be used to assess associated metabolic complications. Bioelectrical impedance analysis (BIA) shows promise as an easy to use, rapid, and non-invasive tool to evaluate body composition. The objectives of this study were to: (a) develop BIA prediction equations to estimate total body water (TBW) and fat-free mass (FFM) in European children and early adolescents and to validate the analysis with the deuterium dilution as the reference technique and (b) compare our results with previously published paediatric BIA equations. Read More

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Weight gain in children after adenotonsillectomy: undesirable weight gain or catch-up growth?

Sleep Med 2021 Jul 14;85:147-149. Epub 2021 Jul 14.

Sleep Disorders Center and Department of Neurology, University of Michigan, Ann Arbor, MI, USA.

Objective/background: Obesity and obstructive sleep apnea (OSA) are consequential conditions with significant overlap in the pediatric population. Early studies documented catch-up growth in underweight children after adenotonsillectomy, but more recent studies suggested that normal and even overweight children may experience excess weight gain after adenotonsillectomy. We performed a secondary analysis of Childhood Adenotonsillectomy Trial (CHAT) data to test whether there was an effect of early adenotonsillectomy on undesirable weight gain, defined as an increase in body mass index (BMI) Z score in an already overweight or obese child or a change from baseline normal or underweight to a follow up BMI Z score classified as overweight. Read More

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Prioritization of Features for Mobile Apps for Families in a Federal Nutrition Program for Low-Income Women, Infants, and Children: User-Centered Design Approach.

JMIR Form Res 2021 Jul 30;5(7):e30450. Epub 2021 Jul 30.

Markey Cancer Center, University of Kentucky, Lexington, KY, United States.

Background: The Special Supplemental Nutrition Assistance Program for Women, Infants, and Children (WIC) is a federal nutrition program that provides nutritious food, education, and health care referrals to low-income women, infants, and children up to the age of 5 years. Although WIC is associated with positive health outcomes for each participant category, modernization and efficiency are needed at the clinic and shopping levels to increase program satisfaction and participation rates. New technologies, such as electronic benefits transfer (EBT), online nutrition education, and mobile apps, can provide opportunities to improve the WIC experience for participants. Read More

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School-Age Obese Asthmatic Children have Distinct Lung Function Measures From Lean Asthmatics and Obese Children.

J Asthma 2021 Jul 30:1-17. Epub 2021 Jul 30.

Aydin Adnan Menderes University, School of Medicine, Department of Pediatrics, Division of Pediatric Endocrinology, Aydin, Turkey.

The lung functions of children with obese asthma seem to be distinct from those of obese children or lean asthmatics. To measure baseline lung function, exercise-induced bronchoconstriction (EIB), and bronchial hyperreactivity (BHR) in school-age obese asthmatics (OA group) and to compare the data with obese children (O group), lean asthmatics (A group), and healthy controls (H group). One hundred seventy school-age children were enrolled in this prospective cross-sectional study. Read More

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Dose-response association of early-life antibiotic exposure and subsequent overweight or obesity in children: A meta-analysis of prospective studies.

Obes Rev 2021 Jul 29:e13321. Epub 2021 Jul 29.

Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

The objective of this study is to investigate the dose-response relationship between antibiotic exposure in early life and the risk of subsequent overweight or obesity. Electronic databases were searched from inception to December 2020. Prospective studies that reported the odds ratios (ORs) of childhood overweight or obesity for three or more quantitative categories of antibiotic exposure were identified. Read More

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Central Precocious Puberty in a Boy with Pseudohypoparathyroidism Type 1A due to a Novel Variant, Who Had Congenital Hypothyroidism as the First Manifestation.

J Clin Res Pediatr Endocrinol 2021 Jul 30. Epub 2021 Jul 30.

Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Pseudohypoparathyroidism type 1A (PHP1A) is a disorder of multiple hormone resistance, mainly parathyroid hormone. It is associated with Albright hereditary osteodystrophy phenotypes. Patients with PHP1A may initially present with hypothyroidism during infancy and later develop typical PHP1A characteristics during their childhood. Read More

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Metabolomic profiling of stool of two-year old children from the INSIGHT study reveals links between butyrate and child weight outcomes.

Pediatr Obes 2021 Jul 30:e12833. Epub 2021 Jul 30.

Department of Statistics, Penn State University, University Park, PA, USA.

Background: Metabolomic analysis is commonly used to understand the biological underpinning of diseases such as obesity. However, our knowledge of gut metabolites related to weight outcomes in young children is currently limited.

Objectives: To (1) explore the relationships between metabolites and child weight outcomes, (2) determine the potential effect of covariates (e. Read More

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Salt sensitivity of blood pressure in childhood and adolescence.

Coral D Hanevold

Pediatr Nephrol 2021 Jul 29. Epub 2021 Jul 29.

University of Washington School of Medicine, Department of Pediatrics, Division of Nephrology, 4800 Sand Point Way NE, M/S OC.9.820, Seattle, WA, 98105, USA.

Although moderation of sodium intake is recommended population-wide, it remains uncertain who benefits from salt restriction. Salt sensitivity refers to changes in blood pressure in response to sodium intake and may occur with or without hypertension. Unfortunately, there is no practical way to assess salt sensitivity in daily practice. Read More

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Health disparities in cardiometabolic risk among Black and Hispanic youth in the United States.

Am J Prev Cardiol 2021 Jun 23;6:100175. Epub 2021 Mar 23.

Stanford Department of Medicine, Cardiovascular Medicine, Cardiovascular Institute, Prevention Research Center, Stanford University, Room CV273, MC 5406, 300 Pasteur Drive, Stanford, CA 94305, USA.

Cardiometabolic risk factors in children and adolescents track into adulthood and are associated with increased risk of atherosclerotic cardiovascular disease. The purpose of this review is to examine the pervasive race and ethnic disparities in cardiometabolic risk factors among Black and Hispanic youth in the United States. We focus on three traditional cardiometabolic risk factors (obesity, type 2 diabetes mellitus, and dyslipidemia) as well as on the emerging cardiometabolic risk factor of non-alcoholic fatty liver disease. Read More

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Body Mass Index Trajectories during 6-18 Years Old and the Risk of Hypertension in Young Adult: A Longitudinal Study in Chinese Population.

Int J Hypertens 2021 15;2021:6646868. Epub 2021 Jul 15.

Suzhou Center for Disease Prevention and Control, Suzhou, Jiangsu 215004, China.

Background: Overweight/obesity in childhood is suggested to increase the risk of hypertension later in life. We aimed to assess whether and how body mass index (BMI) trajectories during 6-18 years of age are associated with hypertension in young adulthood (18-37 years) in the Chinese population.

Methods: Based on the China Health and Nutrition Survey (CHNS), a total of 1,872 participants who received ≥2 measurements of BMI during 6-18 years and had assessment of blood pressure (BP) in young adulthood were included. Read More

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