Biochem Biophys Res Commun 2021 Apr 16;557:206-212. Epub 2021 Apr 16.
Section of Oral Neuroscience, Graduate School of Dental Science, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka-city, Fukuoka, 812-8582, Japan; Research and Development Center for Five-Sense Devices Taste and Odor Sensing, Kyushu University, 744, Nishi-ku, Fukuoka-city, Fukuoka, 819-0395, Japan. Electronic address:
Taste buds are complex sensory organs embedded in the epithelium of fungiform papillae (FP) and circumvallate papillae (CV). The sweet, bitter, and umami tastes are sensed by type II taste cells that express taste receptors (Tas1rs and Tas2rs) coupled with the taste G-protein α-gustducin. Recent studies revealed that the taste response profiles of α-gustducin-expressing cells are different between FP and CV, but which genes could generate such distinctive cell characteristics are still largely unknown. Read More