Talanta 2021 Oct 17;233:122501. Epub 2021 May 17.
Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences-Wuhan National Laboratory for Optoelectronics, Wuhan, 430071, PR China; University of Chinese Academy of Sciences, Beijing, 100049, PR China; Wuhan National Laboratory for Optoelectronics, Wuhan, 430074, PR China. Electronic address:
Riboflavin and its derivatives are the most important coenzymes in vivo metabolism, and are closely related to life activities. In this paper, the first photolysis Xe biosensor was developed by combining cryptophane-A with riboflavin moiety, which showed photosensitivity recorded by hyperpolarized Xe NMR/MRI technology with an obvious chemical shift change of 5.3 ppm in aqueous solution. Read More