32,974 results match your criteria cerebral palsy


Epidural Analgesia Versus Lumbar Plexus Blockade After Hip Reconstruction Surgery in Children With Cerebral Palsy and Intrathecal Baclofen Pumps: A Comparison of Safety and Efficacy.

J Pediatr Orthop 2022 Jan 20. Epub 2022 Jan 20.

Departments of Orthopaedic Surgery Anesthesiology, Critical Care, and Pain Medicine Neurosurgery, Boston Children's Hospital, Boston, MA.

Background: Epidural analgesia is commonly used for pain control after reconstructive hip surgery, but its use is controversial in the presence of an intrathecal baclofen pump (ITB). The purpose of this retrospective study was to investigate the rate of serious anesthetic and postoperative complications as well as the efficacy of epidural analgesia compared with lumbar plexus blocks (LPBs) for pain management after neuromuscular hip reconstruction in children with cerebral palsy (CP) and ITB.

Methods: Pediatric patients with CP and ITB undergoing hip reconstructive surgery from 2010 to 2019 were retrospectively identified. Read More

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January 2022

Measuring Effects on Pain and Quality of Life after Abobotulinum Toxin A Injections in Children with Cerebral Palsy.

Toxins (Basel) 2022 Jan 5;14(1). Epub 2022 Jan 5.

Department of Orthopaedic Surgery, Copenhagen University Hospital, 2650 Hvidovre, Denmark.

Sixty-seven percent of children with cerebral palsy (CCP) experience pain. Pain is closely interrelated to diminished quality of life. Despite this, pain is an overlooked and undertreated clinical problem. Read More

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January 2022

A new framework for analysis of three-dimensional shape and architecture of human skeletal muscles from in vivo imaging data.

Authors:
Bart Bolsterlee

J Appl Physiol (1985) 2022 Jan 20. Epub 2022 Jan 20.

Neuroscience Research Australia (NeuRA), Randwick, Sydney, New South Wales, Australia.

A new framework is presented for comprehensive analysis of the three-dimensional shape and architecture of human skeletal muscles from magnetic resonance and diffusion tensor imaging data. The framework comprises three key features: (1) identification of points on the surface of and inside a muscle that have a correspondence to points on and inside another muscle, (2) reconstruction of average muscle shape and average muscle fibre orientations, and (3) utilization of data on between-muscle variation to visualize and make statistical inferences about changes or differences in muscle shape and architecture. The general use of the framework is demonstrated by its application to three case studies. Read More

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January 2022

Combined Unilateral Radiofrequency Lesioning of the Motor Thalamus, Field of Forel, and Zona Incerta: A Series of Cases With Dystonia.

Neurosurgery 2022 Jan 24. Epub 2022 Jan 24.

Department of Neurology, Ankara University, Ankara, Turkey.

Background: Dystonia is a group of disorders characterized by involuntary slow repetitive twisting movements and/or abnormal posture. Surgical options such as neuromodulation through deep brain stimulation and neuroablative procedures are available for patients who do not respond to conservative treatment.

Objective: To present our series of patients with dystonia who were treated with stereotactic combined unilateral radiofrequency lesioning of the motor thalamus, field of Forel, and zona incerta. Read More

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January 2022

The clinical and neuroradiological features of patients of coexisting atraumatic convexity subarachnoid hemorrhage and large artery atherosclerosis stroke: A retrospective observational study.

Medicine (Baltimore) 2021 Dec;100(48):e28155

Department of Neurology, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, Jiangxi Province, China.

Abstract: Atraumatic convexity subarachnoid hemorrhage (c-SAH) concomitant with large artery atherosclerosis (LAA) stroke has been rarely discussed in the literature. Our aim in this study is to characterize the clinical and neuroradiological features of patients with LAA stroke and c-SAH.A retrospective study from a single institution was performed between January 2016 and June 2020. Read More

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December 2021

Oral Health of Children and Adolescents in the United Arab Emirates: A Systematic Review of the Past Decade.

Front Oral Health 2021 29;2:744328. Epub 2021 Sep 29.

Institut National de Santé Publique, d'Épidémiologie Clinique et de Toxicologie (INSPECT-Lb), Beirut, Lebanon.

Oral diseases are a universal public health problem with serious health and economic burdens. These diseases are a major concern in the pediatric population specifically. In the United Arab Emirates (UAE), among all the diseases that affect children, oral diseases, particularly early childhood caries, are the most common despite improvement in the provision of oral health services. Read More

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September 2021

Cognitive Orientation to Daily Occupational Performance (CO-OP) in Children with Cerebral Palsy: A Systematic Review with Meta-analysis : L'approcheCO-OP auprès des enfants atteints de paralysie cérébrale: revue systématique et méta-analyse.

Can J Occup Ther 2022 Jan 19:84174211066651. Epub 2022 Jan 19.

Background: Cognitive orientation to daily occupational performance (CO-OP) is a client-centered treatment approach that was developed in the 1990s by occupational therapists. Exploring current evidence about the effectiveness of CO-OP on children with cerebral palsy (CP). Major electronic databases were searched. Read More

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January 2022

The effect of prolonged walking on muscle fatigue and neuromuscular control in children with cerebral palsy.

Gait Posture 2022 Jan 7;93:7-13. Epub 2022 Jan 7.

Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Rehabilitation Medicine, Amsterdam Movement Sciences, De Boelelaan 1117, PO Box 7057, 1007 MB Amsterdam, Netherlands. Electronic address:

Background: Muscle fatigue of the lower limbs is considered a main contributor to the perceived fatigue in children with cerebral palsy (CP) and is expected to occur during prolonged walking. In adults without disabilities, muscle fatigue has been proposed to be associated with adaptations in complexity of neuromuscular control.

Research Question: What are the effects of prolonged walking on signs of muscle fatigue and complexity of neuromuscular control in children with CP?

Methods: Ten children with CP and fifteen typically developing (TD) children performed a standardised protocol on an instrumented treadmill consisting of three stages: six-minutes walking at preferred speed (6 MW), moderate-intensity walking (MIW, with two minutes at heart rate > 70% of predicted maximal heart rate) and four-minutes walking at preferred speed (post-MIW). Read More

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January 2022

Cerebral Palsy-More Than Just Spasticity.

Indian J Pediatr 2022 Jan 18. Epub 2022 Jan 18.

Department of Pediatrics, APC, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

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January 2022

Recent Investigations on Neurotransmitters' Role in Acute White Matter Injury of Perinatal Glia and Pharmacotherapies-Glia Dynamics in Stem Cell Therapy.

Mol Neurobiol 2022 Jan 18. Epub 2022 Jan 18.

Cancer Center, Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, People's Republic of China.

Periventricular leukomalacia (PVL) and cerebral palsy are two neurological disease conditions developed from the premyelinated white matter ischemic injury (WMI). The significant pathophysiology of these diseases is accompanied by the cognitive deficits due to the loss of function of glial cells and axons. White matter makes up 50% of the brain volume consisting of myelinated and non-myelinated axons, glia, blood vessels, optic nerves, and corpus callosum. Read More

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January 2022

Mortality, In-Hospital Morbidity, Care Practices, and 2-Year Outcomes for Extremely Preterm Infants in the US, 2013-2018.

JAMA 2022 Jan;327(3):248-263

Social, Statistical, and Environmental Sciences Unit, RTI International, Rockville, Maryland.

Importance: Despite improvement during recent decades, extremely preterm infants continue to contribute disproportionately to neonatal mortality and childhood morbidity.

Objective: To review survival, in-hospital morbidities, care practices, and neurodevelopmental and functional outcomes at 22-26 months' corrected age for extremely preterm infants.

Design, Setting, And Participants: Prospective registry for extremely preterm infants born at 19 US academic centers that are part of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Read More

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January 2022

How safe and effective is the use of bisphosphonates in the treatment of osteoporosis in children with cerebral palsy? A Cochrane Review summary with commentary.

Authors:
Sina Arman

Dev Med Child Neurol 2022 Jan 17. Epub 2022 Jan 17.

Department of Physical Medicine and Rehabilitation, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

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January 2022

Effects of modified pilates on trunk, postural control, gait and balance in children with cerebral palsy: a single-blinded randomized controlled study.

Acta Neurol Belg 2022 Jan 18. Epub 2022 Jan 18.

Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Gazi University, Biskek Cd. 6. Sk, No: 2, 06490, Emek/Cankaya, Ankara, Turkey.

Objective: This study aimed to determine the effects of modified pilates exercises (MPE) and neurodevelopmental therapy (NDT) on trunk, postural control, gait, and balance in children with cerebral palsy (CP).

Methods: 18 children with CP between gross motor function classification system (GMFCS) I and III were randomized into two groups as study (Group A, MPE) and control (Group B, NDT). Physiotherapy (PT) took place 2 days a week for 8 weeks. Read More

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January 2022

Comparing the effects of modified constraint-induced movement therapy and bimanual training in children with hemiplegic cerebral palsy mainstreamed in regular school: A randomized controlled study.

Arch Pediatr 2022 Jan 14. Epub 2022 Jan 14.

Department of Physiotherapy and Rehabilitation, Faculty of Physical Therapy and Rehabilitation, Hacettepe University, 06100-Samanpazarı, Ankara, Turkey. Electronic address:

Purpose: The aim of this study was to compare the effects of modified constraint-induced movement therapy (mCIMT) and bimanual training (BIT) based on the International Classification of Functioning, Disability, and Health, Children and Youth (ICF-CY) conceptual framework.

Research Method: A total of 32 children (mean age 10.43 years [SD 2. Read More

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January 2022

Outcome Analysis of Severe Hyperbilirubinemia in Neonates Undergoing Exchange Transfusion.

Neuropediatrics 2022 Jan 17. Epub 2022 Jan 17.

Henan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center, Institute of Neuroscience and Third Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.

Objective:  Severe neonatal hyperbilirubinemia can cause neurological disability or mortality if not effectively managed. Exchange transfusion (ET) is an efficient treatment to prevent bilirubin neurotoxicity. The purpose of this study was to evaluate outcomes in severe neonatal hyperbilirubinemia with ET and to identify the potential risk factors for poor outcomes. Read More

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January 2022

Cerebral Palsy in Child Neurology and Neurodevelopmental Disabilities Training: An Unmet Need.

J Child Neurol 2022 Jan 17:8830738211072711. Epub 2022 Jan 17.

Division of Pediatric Neurology, Department of Neurology, School of Medicine, 7548Washington University in St Louis and St Louis Children's Hospital, St Louis, MO, USA.

Background: Cerebral palsy (CP) is the most common cause of childhood motor disability. However, there is limited guidance on training of child neurologists and neurodevelopmental disability specialists in the care of individuals with cerebral palsy. We sought to determine training program directors' impressions of the importance and adequacy of training in the diagnosis and management of cerebral palsy. Read More

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January 2022

C-section of Preclinical Animal Model of Chorioamnionitis Triggered by Group B Streptococcus (GBS).

J Vis Exp 2021 Dec 29(178). Epub 2021 Dec 29.

Department of Pediatrics, McGill University.

Group B Streptococcus (GBS) is one of the most common bacteria isolated during human pregnancy. It is a leading cause of placental infection/inflammation, termed chorioamnionitis. Chorioamnionitis exposes the developing fetus to a high risk of organ injuries, perinatal morbidity, and mortality, as well as life-long neurobehavioral impairments and other non-neurological developmental issues. Read More

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December 2021

Development of a standards-based phenotype model for gross motor function to support learning health systems in pediatric rehabilitation.

Learn Health Syst 2022 Jan 5;6(1):e10266. Epub 2021 May 5.

Department of Health and Rehabilitation Sciences Temple University Philadelphia Pennsylvania USA.

Introduction: Research and continuous quality improvement in pediatric rehabilitation settings require standardized data and a systematic approach to use these data.

Methods: We systematically examined pediatric data concepts from a pediatric learning network to determine capacity for capturing gross motor function (GMF) for children with Cerebral Palsy (CP) as a demonstration for enabling infrastructure for research and quality improvement activities of an LHS. We used an iterative approach to construct phenotype models of GMF from standardized data element concepts based on case definitions from the Gross Motor Function Classification System (GMFCS). Read More

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January 2022

The effects of sling exercise program on balance and body activities in children with spastic cerebral palsy.

J Exerc Rehabil 2021 Dec 27;17(6):410-417. Epub 2021 Dec 27.

Department of Physical Therapy, College of Nursing and Healthcare Science, Dong-Eui University, Busan, Korea.

The purpose of this study was to investigate the static and dynamic balance and body activities after administering a trunk stability exercise program using a sling for children with spastic cerebral palsy of Gross Motor Function Classification System (GMFCS) levels III-IV. This study was conducted based on a quasi-experimental study design. Six of the study participants were assigned to the control group and six were assigned to the experimental group using simple random sampling. Read More

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December 2021

Physical activity intention and attendance behaviour in Finnish youth with cerebral palsy - results from a physical activity intervention: an application of the theory of planned behaviour.

J Exerc Rehabil 2021 Dec 27;17(6):370-378. Epub 2021 Dec 27.

Faculty of Sport and Health Sciences, University of Jyväskylä, Nokia, Finland.

Physical activity is associated with better health in individuals with cerebral palsy (CP). Numerous physical activity interventions have been designed to promote physical activity among youth with CP. No previous studies have explored the factors contributing to the intention to participate and predicting attendance behaviour for these interventions. Read More

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December 2021

Pattern of Abuse in Children With Behavioral Disorders Presenting to a Tertiary Care Hospital in Peshawar.

Cureus 2021 Dec 13;13(12):e20379. Epub 2021 Dec 13.

Pediatrics, Lady Reading Hospital, Medical Teaching Institution (MTI), Peshawar, PAK.

Objective To determine the different types of child abuse and its association with behavioral disorders in children presenting to a tertiary care hospital. Materials and methods One hundred abused Pakistani children, of both genders, were included. Children with cerebral palsy, a neurodegenerative disorder, chronic illness, chronic liver disease, congenital heart disease, chronic renal failure, and parents who refused to become part of the study were excluded. Read More

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December 2021

Bobath in Brazil: what is the best study design for intervention for children with cerebral palsy?

Dev Med Child Neurol 2022 Jan 14. Epub 2022 Jan 14.

Centro de Apoio Terapeutico - Physiotherapy, Santos, Brazil.

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January 2022

Guideline to improve physical function in cerebral palsy: too big to succeed.

Dev Med Child Neurol 2022 Jan 14. Epub 2022 Jan 14.

Wake Forest School of Medicine - Orthopedics, Winston, Salem, NC, USA.

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January 2022

Foot orthoses for treating paediatric flat feet.

Cochrane Database Syst Rev 2022 Jan 14;1:CD006311. Epub 2022 Jan 14.

School of Health Sciences, Faculty of Health and Medicine, The University of Newcastle, Ourimbah, Australia.

Background: Paediatric flat feet are a common presentation in primary care; reported prevalence approximates 15%. A minority of flat feet can hurt and limit gait. There is no optimal strategy, nor consensus, for using foot orthoses (FOs) to treat paediatric flat feet. Read More

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January 2022

Tranexamic acid use decreases transfusion rate in children with cerebral palsy undergoing proximal femoral varus derotational osteotomy.

Medicine (Baltimore) 2022 Jan;101(2):e28506

Children's Orthopaedic Center, Children's Hospital Los Angeles, Los Angeles, CA.

Abstract: Previous studies demonstrated the safety of tranexamic acid (TXA) use in cerebral palsy (CP) patients undergoing proximal femoral varus derotational osteotomy (VDRO), but were underpowered to determine if TXA alters transfusion rates or estimated blood loss (EBL). The purpose of this study was to investigate if intraoperative TXA administration alters transfusion rates or EBL in patients with CP undergoing VDRO surgery.We conducted a retrospective review of 390 patients with CP who underwent VDRO surgery between January 2004 and August 2019 at a single institution. Read More

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January 2022

Investigation on Quality of Life and Economic Burden of Children with Cerebral Palsy in Changzhou.

J Healthc Eng 2022 4;2022:1519689. Epub 2022 Jan 4.

Changzhou Maternal and Child Health Care Hospital, Changzhou 213000, Jiangsu, China.

Based on the data of children with cerebral palsy (CP) in Changzhou obtained by the Disabled Persons' Federation, this study sampled some children with CP and investigated their survival status, treatment cost, and family burden so as to provide scientific decision-making basis and policy suggestions for coping with disease hazards and improving children's quality of life. In this study, a simple random sampling method was used to conduct household surveys of the selected children with CP. The economic burden of CP is measured by direct and indirect methods, and the quality of life of patients of children with CP and their families is analyzed qualitatively and quantitatively by the EuroQol Five Dimensions (EQ-5D) Questionnaire. Read More

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January 2022

Long-term efficacy and safety of repeated botulinum toxin a applications based on function and anesthesia type in children with cerebral palsy.

J Orthop 2022 Jan-Feb;29:22-27. Epub 2021 Dec 30.

Department of Anesthesiology and Reanimation, Dr Behcet Uz Child Diseases and Surgery Research and Training Hospital, Konak, Izmir, Turkey.

Purpose: This study evaluates the motor development of patients undergoing three or more repeated Botulinum toxin A (BoNT-A) applications in a tertiary pediatric hospital as well as the safety of three different types of anesthesia.

Methods: Seventy-five children who underwent BoNT-A applications at least three consecutive times at six-month intervals and a total of 320 procedures were examined. Gross Motor Function Classification System (GMFCS) was employed in motor development evaluation. Read More

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December 2021

A randomized crossover study of functional electrical stimulation during walking in spastic cerebral palsy: the FES on participation (FESPa) trial.

BMC Pediatr 2022 Jan 13;22(1):37. Epub 2022 Jan 13.

School of Mental Health and Neurosciences (MHeNs), Faculty of Health, Medicine and Life Sciences (FHML), Maastricht University, Maastricht, the Netherlands.

Background: Spastic cerebral palsy is the most common cause of motor disability in children. It often leads to foot drop or equinus, interfering with walking. Ankle-foot orthoses (AFOs) are commonly used in these cases. Read More

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January 2022

Prelabor rupture of membranes at term: A possible hematological triage in addition to vagino-rectal beta-hemolytic streptococcus screening for early labor induction.

PLoS One 2022 13;17(1):e0261906. Epub 2022 Jan 13.

Department of Woman Child and Neonate, Obstertics Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Introduction: A potential complication of term prelabor rupture of membranes (term PROM) is chorioamnionitis with an increased burden on neonatal outcomes of chronic lung disease and cerebral palsy. The purpose of the study was to analyze the efficacy of a standing clinical protocol designed to identify women with term PROM at low risk for chorioamnionitis, who may benefit from expectant management, and those at a higher risk for chorioamnionitis, who may benefit from early induction.

Material And Methods: This retrospective study enrolled all consecutive singleton pregnant women with term PROM. Read More

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January 2022

Early Anal Protrusion of Distal Ventriculoperitoneal Catheter Due to Iatrogenic Colonic Perforation: A Case Report and Review of Literature.

Cureus 2021 Dec 9;13(12):e20296. Epub 2021 Dec 9.

Medicine and Surgery, Umm Al-Qura University, Makkah, SAU.

Ventriculo-peritoneal (VP) shunt is one of the most commonly used therapeutic methods for hydrocephalus. And the incidence across the world of VP shunt complications varies from 20% to 45%. One of the rare complications is the catheter perforation of the abdominal viscera and its extrusion through the anal cavity. Read More

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December 2021