Biofabrication 2021 Apr 13. Epub 2021 Apr 13.
Brain Science Institute, Korea Institute of Science and Technology Brain Science Institute, 5, Hwarang-ro 14 gil, Seongbuk-gu, Seoul, Seongbok-gu, 02792, Korea (the Republic of).
The neurovascular unit (NVU) comprises multiple types of brain cells, including brain endothelial cells, astrocytes, pericytes, neurons, microglia, and oligodendrocytes. Each cell type contributes to the maintenance of the molecular transport barrier and brain tissue homeostasis. Several disorders and diseases of the central nervous system, including neuroinflammation, Alzheimer's disease, stroke, and multiple sclerosis, have been associated with dysfunction of the NVU. Read More