637 results match your criteria cavity 223

microRNA-223 Deficiency Exacerbates Acute Inflammatory Response to Monosodium Urate Crystals by Targeting NLRP3.

J Inflamm Res 2021 11;14:1845-1858. Epub 2021 May 11.

Department of Rheumatology and Immunology, Clinical Medical College and The First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, Sichuan Province, People's Republic of China.

Objective: MicroRNAs were identified as master-switch molecules limiting acute inflammatory response. This study investigated the potential role of microRNA (miR)-223 in the mechanism of gout.

Methods: Wild-type (WT) and miR-223 knock-out (KO) mice were used to evaluate the phenotypes of gout models. Read More

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NOTCH1 mutations as prognostic marker in oral squamous cell carcinoma.

Pathol Res Pract 2021 Jul 10;223:153474. Epub 2021 May 10.

Department of Anatomic Pathology, Chang Gung Memorial Hospital at Keelung, Taiwan.

Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity with poor prognosis. The dysregulation of Notch signaling pathway has been implicated in the OSCC tumorigenesis. However, the clinical implication of NOTCH1 mutation status in OSCC remains unelucidated. Read More

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Inclusion complex of clausenidin with hydroxypropyl-β-cyclodextrin: Improved physicochemical properties and anti-colon cancer activity.

Saudi Pharm J 2021 Mar 3;29(3):223-235. Epub 2021 Feb 3.

Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.

The long-term objective of the present study was to prepare, physicochemically characterize and determine the anticancer of clausenidin/hydroxypropyl-β-cyclodextrin (Clu/HPβCD) inclusion complex. We used differential scanning calorimetry, X-ray diffractometer, fourier transform infrared spectroscopy, ultraviolet-visible spectrophotometer and C and H nuclear magnetic resonance followed by anticancer assays. The orientation and intermolecular interactions of Clausenidin within cyclodextrin cavity were also ascertained by molecular docking simulation accomplished by AutoDock Vina. Read More

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Role and mechanism of action of circular RNA and laryngeal cancer.

Pathol Res Pract 2021 Jul 30;223:153460. Epub 2021 Apr 30.

Clinical Laboratory, Linyi Central Hospital, Linyi, 276400 Shandong, China. Electronic address:

Laryngeal squamous cell carcinoma (LSCC), is the second most common malignant cancer of the head and neck after oral cavity cancer. Laryngeal cancer is associated with huge socio-economic burden worldwide. Studies have widely explored the role of non-coding RNAs, especially microRNAs and long non-coding RNAs in pathogenesis of laryngeal cancer. Read More

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Ultralow Threshold, Single-Mode InGaAs/GaAs Multiquantum Disk Nanowire Lasers.

ACS Nano 2021 May 10;15(5):9126-9133. Epub 2021 May 10.

Department of Electronic Materials Engineering, Research School of Physics, The Australian National University, Canberra, Australian Capital Territory 2601, Australia.

We present single-mode nanowire (NW) lasers with an ultralow threshold in the near-infrared spectral range. To ensure the single-mode operation, the NW diameter and length are reduced specifically to minimize the longitudinal and transverse modes of the NW cavity. Increased optical losses and reduced gain volume by the dimension reduction are compensated by an excellent NW morphology and InGaAs/GaAs multiquantum disks. Read More

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Dose- and time-dependent systemic adverse reactions of sodium carboxy methyl cellulose after intraperitoneal application in rats.

J Toxicol Sci 2021 ;46(5):223-234

Shandong Key Laboratory of Biological Evaluation for Medical Devices, NMPA Key Laboratory for Safety Evaluation of Biomaterials and Medical Devices, NMPA Key Laboratory for Quality Control of Pharmaceutical Packaging, Shandong Quality Inspection Center for Medical Devices, China.

Sodium carboxy methyl cellulose (SCMC) is an important absorbable biomaterial for anti-adhesion and hemostasis medical devices used in the abdominal cavity. However, the systemic toxicity of SCMC following intraperitoneal route has not been revealed sufficiently. Three SCMC solutions with gradient concentrations were intraperitoneally injected into 3 groups of rats with the doses of 50 mg/kg, 320 mg/kg and 2000 mg/kg respectively all at once to observe the dose-dependence of systemic reactions of SCMC and 10 rats (5 rats per sex) of each group were sacrificed 3 days, 7 days, 28 days and 90 days after injection to evaluate the time-dependence of the reactions. Read More

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January 2021

Association between mental health, caries experience and gingival health of adolescents in sub-urban Nigeria.

BMC Oral Health 2021 04 30;21(1):223. Epub 2021 Apr 30.

International Research Center of Excellence, Institute of Human Virology Nigeria, Abuja, Nigeria.

Background: This study assessed the association of mental health problems and risk indicators of mental health problems with caries experience and moderate/severe gingivitis in adolescents.

Methods: A cross-sectional household survey was conducted in Osun State, Nigeria. Data collected from 10 to 19-years-old adolescents between December 2018 and January 2019 were sociodemographic variables (age, sex, socioeconomic status); oral health indicators (tooth brushing, use of fluoridated toothpaste, consumption of refined carbohydrates in-between-meals, dental services utilization, dental anxiety and plaque); mental health indicators (smoking habits, intake of alcohol and use of psychoactive drugs) and mental health problems (low and high). Read More

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In vivo detection of beta-amyloid at the nasal cavity and other skull-base sites: a retrospective evaluation of ADNI1/GO.

Ann Nucl Med 2021 Jun 12;35(6):728-734. Epub 2021 Apr 12.

Department of Medical Imaging, Sunnybrook Health Sciences Centre, Toronto, M4N 3M5, Canada.

Introduction: Amyloid beta (Aβ) is partially cleared from the CSF via skull base perivascular and perineural lymphatic pathways, particularly at the nasal cavity. In vivo differences in Aβ level at the nasal cavity between patients with Alzheimer's disease (AD), subjects with mild cognitive impairment (MCI) and cognitively normal (CN) individuals have not been previously assessed.

Methods: This is a retrospective evaluation of subject level data from the ADNI-1/GO database. Read More

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Association of Dental Caries and Anthropometric Measures among Primary School Children.

Children (Basel) 2021 Mar 13;8(3). Epub 2021 Mar 13.

Department of Prosthetic Dental Science, College of Dentistry, King Saud University, P.O. Box 60169, Riyadh 11545, Saudi Arabia.

: This study aimed to investigate an association between dental caries status and anthropometric measures in primary school children. : An analytical cross-sectional study ( = 376) was conducted among primary school children (age range = 6-9 years) registered in private schools. Non-clinical data was gathered from parents of participating children through a self-administered structured questionnaire as well as from the children through an interviewer-administered questionnaire. Read More

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Secondary Obliteration Surgery for Troublesome Mastoid Cavities: A Prospective Series of 228 Pediatric and Adult Cases.

Otol Neurotol 2021 Mar 11. Epub 2021 Mar 11.

Ipswich Hospital NHS Trust, Ipswich, UK Southend University Hospital NHS Foundation Trust, Southend-on-Sea, UK.

Objective: To present the results of a 15-year longitudinal study in a pediatric and adult population with secondary obliteration of troublesome mastoid cavities.

Study Design: Prospective longitudinal study.

Patients: Children (≤16 yrs) and adults who had obliteration surgery (228 ears) between 2000 and 2017. Read More

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In vitro comparison of two photostimulable phosphor plate systems for early detection of occlusal dentin caries with and without a sharpening filter.

J Dent Res Dent Clin Dent Prospects 2020 6;14(4):223-227. Epub 2020 Dec 6.

Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran.

Dental caries is the most important reason for tooth loss. Clinical examination is the most commonly used technique for occlusal caries diagnosis. The diagnostic power of digital systems is a matter of controversy in this field. Read More

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December 2020

A Machine Learning Approach to Uncovering Hidden Utilization Patterns of Early Childhood Dental Care Among Medicaid-Insured Children.

Front Public Health 2020 18;8:599187. Epub 2021 Jan 18.

Research Information Solutions and Innovation, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, United States.

Early childhood dental care () is a significant public health opportunity since dental caries is largely preventable and a prime target for reducing healthcare expenditures. This study aims to discover underlying patterns in ECDC utilization among Ohio Medicaid-insured children, which have significant implications for public health prevention, innovative service delivery models, and targeted cost-saving interventions. Using 9 years of longitudinal Medicaid data of 24,223 publicly insured child members of an accountable care organization (), Partners for Kids in Ohio, we applied unsupervised machine learning to cluster patients based on their cumulative dental cost curves in early childhood (24-60 months). Read More

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An ascites grading system for predicting the prognosis of gastric cancer with peritoneum dissemination.

Ann Gastroenterol Surg 2020 Nov 16;4(6):660-666. Epub 2020 Aug 16.

Department of Surgery Tsuboi Hospital Koriyama Japan.

Aim: Gastric cancer with peritoneum dissemination is intractable with surgical resection. The evaluation of the degree of dissemination using computed tomography (CT) is difficult. We focused on the amount of ascites based on CT findings and established a scaling system to predict these patients' prognoses. Read More

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November 2020

Hydroids (Cnidaria, Hydrozoa) from Mauritanian Coral Mounds.

Zootaxa 2020 Nov 16;4878(3):zootaxa.4878.3.2. Epub 2020 Nov 16.

Departamento de Ecoloxía e Bioloxía Animal, Facultade de Ciencias do Mar e Centro de Investigación Mariña (CIM-UVigo), Universidade de Vigo. Campus Lagoas-Marcosende. 36310 Vigo. Spain. Instituto Español de Oceanografía, Centro Oceanográfico de Vigo. Subida Radio Faro 50. 36390 Vigo. Spain..

Agassiz, L. (1862) Contributions to the natural history of the United States of America. Vol. Read More

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November 2020

Hollow carbon nanocapsules-based nitrogen-doped carbon nanofibers with rosary-like structure as a high surface substrate for impedimetric detection of Pseudomonas aeruginosa.

Talanta 2021 Feb 24;223(Pt 1):121700. Epub 2020 Sep 24.

Department of Chemistry, Ilam University, PO. Box 69315-516, Ilam, Iran.

The design of hollow mesoporous carbon-based materials has attracted tremendous attention, due to their sizeable intrinsic cavity to load specific chemical and unique physical/chemical properties in various applications. Herein, we have established an effective strategy for the preparation of novel hollow carbon nanocapsules-based nitrogen-doped carbon nanofibers (CNCNF) with rosary-like structure. By embedding ultrafine hollow carbon nanocapsules into electrospun polyacrylonitrile (PAN) skeleton, the as-designed composite CNFs were carbonized into hierarchical porous CNFs, consisted of interconnected nitrogen-doped hollow carbon nanocapsules. Read More

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February 2021

Seismic sensitivity and bone conduction mechanisms enable extratympanic hearing in salamanders.

J Exp Biol 2020 12 21;223(Pt 24). Epub 2020 Dec 21.

Department of Biology, University of Maryland, College Park, MD 20742, USA.

The tympanic middle ear is an adaptive sensory novelty that evolved multiple times in all the major terrestrial tetrapod groups to overcome the impedance mismatch generated when aerial sound encounters the air-skin boundary. Many extant tetrapod species have lost their tympanic middle ears, yet they retain the ability to detect airborne sound. In the absence of a functional tympanic ear, extratympanic hearing may occur via the resonant qualities of air-filled body cavities, sensitivity to seismic vibration, and/or bone conduction pathways to transmit sound from the environment to the ear. Read More

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December 2020

Laparoscopic Management of an Ovarian Dermoid Cyst Containing a Mandibular Structure with Teeth: A Novel Surgical Approach.

J Pediatr Adolesc Gynecol 2021 Apr 9;34(2):223-225. Epub 2020 Oct 9.

Division of Pediatric Gynecology, Cohen Children's Medical Center of New York, Zucker School of Medicine, New Hyde Park, NY.

Background: The presence of ectodermal-derived tissue, including teeth, in an ovarian dermoid cyst is a common occurrence. The presence of a fully formed mandibular structure with teeth, however, is rare, and there are few case reports in the literature that discuss its surgical management.

Case: We report a case of an adolescent girl found to have a mandibular structure with teeth in her dermoid cyst at the time of her laparoscopic ovarian cystectomy and a novel surgical approach in the extraction of the cyst contents from the abdominal cavity. Read More

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High-purity foam-like micron-sized gold cage material with tunable plasmon properties.

Sci Rep 2020 Oct 6;10(1):16555. Epub 2020 Oct 6.

Laser Fusion Research Center, China Academy of Engineering Physics, Mianyang, 621900, Sichuan, China.

Herein, by growing mono dispersed gold nanoparticles (MNPAu) on the surface of polystyrene (PS)/nanogold (Au) core-shell composites ([email protected]), we successfully synthesized a micron-sized gold cage (2.6-10.7 μm), referred to as [email protected]@MNPAu for the first time. Read More

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October 2020

Dynamic contrast-enhanced MR and PET/CT findings of uterine sarcomatoid carcinoma: a case report.

BMC Womens Health 2020 10 6;20(1):223. Epub 2020 Oct 6.

Department of MR, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.

Background: Sarcomatoid carcinoma (SC) is a malignant tumour composed of spindle cells. The incidence of SC is low, especially in the uterus. The imaging features of uterine sarcomatoid carcinoma (USC) are rarely reported. Read More

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October 2020

A Prospective, Multicenter, Clinical Trial Evaluating the Safety and Effectiveness of the Cerene Device to Treat Heavy Menstrual Bleeding.

J Minim Invasive Gynecol 2021 Apr 22;28(4):899-908. Epub 2020 Aug 22.

Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee (all authors).

Study Objective: To evaluate the safety and effectiveness of a novel cryoablation device (Cerene Cryotherapy Device, Channel Medsystems, Emeryville, CA) in premenopausal women with heavy menstrual bleeding owing to benign causes.

Design: A prospective, multi-center, single-arm, open label, non-randomized study.

Setting: At 11 academic and private practices in North America: 8 clinic sites in the United States, and 3 outpatient hospital sites (1 in Mexico and 2 in Canada). Read More

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Feasibility of head-tilted brain scan to reduce susceptibility-induced signal loss in the prefrontal cortex in gradient echo-based imaging.

Neuroimage 2020 12 21;223:117265. Epub 2020 Aug 21.

Center for Neuroscience Imaging Research, Institute for Basic Science (IBS), Suwon 16419, South Korea; Department of Biomedical Engineering, Sungkyunkwan University, Suwon 16419, South Korea; Department of Physics, Sungkyunkwan University, Suwon 16419, South Korea. Electronic address:

Susceptibility-induced static field (B) inhomogeneity near the nasal cavity degrades high-field MRI image quality. Many studies have addressed this problem by hardware- or sequence-based methods to improve local B shimming or minimize the impact of inhomogeneity. Here, we investigate the feasibility of the head-tilted brain scan as an easily accessible way to reduce B inhomogeneity and associated gradient echo signal loss in the prefrontal cortex (PFC). Read More

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December 2020

Exploring the risk factors for early-life sugar consumption: A birth cohort study.

Int J Paediatr Dent 2021 Mar 15;31(2):223-230. Epub 2020 Sep 15.

Department of Pediatric Dentistry, Universidade Luterana do Brasil, Canoas, Brazil.

Background: Sugar consumption in early childhood is the primary cause of negative health outcomes, including early childhood caries.

Aim: To investigate risk factors associated with early-life sugar consumption.

Design: Explanatory variables were collected at baseline of a birth cohort in Porto Alegre, Southern Brazil. Read More

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[Clinical analysis of 35 cases of adult rhabdomyosarcoma of nasal cavity and sinuses].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020 Mar;34(3):223-226

Department of Rhinology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou,450052,China.

To investigate the clinical characteristics and prognostic factors of adult rhabdomyosarcoma(RMS) of nasal cavity and sinus. There were 35 adult patients with RMS, including 22 with embryonal type and 13 with acinar type. Surgery + chemoradiotherapy(17 cases), surgery + radiotherapy(6 cases), surgery + chemotherapy(7 cases)(4 cases of seed implantation after surgery and chemotherapy); Five patients were treated with antitumor drugs instead of surgery. Read More

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Capsular serotypes, antimicrobial susceptibility, and the presence of transferable oxazolidinone resistance genes in Streptococcus suis isolated from healthy pigs in China.

Vet Microbiol 2020 Aug 10;247:108750. Epub 2020 Jun 10.

Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China; Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety and Beijing Laboratory for Food Quality and Safety, China Agricultural University, Beijing, China. Electronic address:

Streptococcus suis is a pig pathogen and a vector of zoonotic diseases that can cause severe systemic infection in humans. S. suis can colonize the nasal cavity, tonsils, and upper respiratory, genital, and digestive tracts in healthy pigs. Read More

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Magnitude of Dental Caries and Its Associated Factors Among Governmental Primary School Children in Debre Berhan Town, North-East Ethiopia.

Pediatric Health Med Ther 2020 20;11:225-233. Epub 2020 Jul 20.

Department of Nursing, College of Health Science, Debre Berhan University, Debre Berhan, Ethiopia.

Background: In Ethiopia, oral health prevention and treatment have gotten low attention in the government, and the existing dental services are privately owned and thus expensive. Hence, this study aimed to assess the prevalence of dental caries and its associated factors among governmental primary school children in Debre Berhan town, Ethiopia, 2019.

Methods: An institutional-based cross-sectional study was conducted from January 30 to February 14/2019. Read More

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By the Skin of Your Teeth: A Subcutaneous Mouse Model to Study Pulp Regeneration.

Methods Mol Biol 2021 ;2206:223-232

Faculty of Medicine and Life Sciences, Biomedical Research Institute (BIOMED), UHasselt - Hasselt University, Diepenbeek, Belgium.

Exiting developments in tissue engineering and new insights in stem cell biology have led to new possible strategies for the regeneration of damaged tissues in the oral cavity. The regeneration of the pulp-dentin complex regeneration in particular, has drawn the attention of many researchers because of the high clinical needs. While it is still important to perform in vitro research using a wide variety of cells, scaffolds and growth factors, it is also critical to have a reliable animal model for preclinical trials. Read More

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Survival case of rhinocerebral and pulmonary mucormycosis due to Cunninghamella bertholletiae during chemotherapy for acute myeloid leukemia: a case report.

Infection 2021 Feb 27;49(1):165-170. Epub 2020 Jul 27.

Disease Control and Prevention Center, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, Japan.

A 42-year-old man diagnosed with acute myeloid leukemia complained of progressive swelling of the right side of his face with pain 11 days after the third cycle of consolidation therapy with high-dose arabinosylcytosine-cytarabine. Head and neck magnetic resonance imaging showed a mass lesion in his right maxillary sinus with parapharyngeal involvement, which included the right masseter muscle, intraorbital involvement, and an abscess in his brain. Chest computed tomography revealed peribronchial small nodules in his right upper lobe and a necrotic tumor in his right lower lobe. Read More

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February 2021

Oral and pre-absorptive sensing of amino acids relates to hypothalamic control of food intake in rainbow trout.

J Exp Biol 2020 09 6;223(Pt 17). Epub 2020 Sep 6.

Lucta S.A., Innovation Division, UAB Research Park, 08193 Bellaterra, Spain.

To assess the putative role of taste and pre-absorptive sensing of amino acids in food intake control in fish, we carried out an oral administration with l-leucine, l-valine, l-proline or l-glutamic acid in rainbow trout (). Treatment with proline significantly reduced voluntary food intake at 2 h and 3 h after oral administration, while glutamic acid showed a less pronounced satiating effect at 3 h. The mRNA expression of taste receptor subunits , , and was measured in the epithelium overlying the bony basihyal of the fish (analogous to the tetrapod tongue) at 10, 20 or 30 min following treatment. Read More

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September 2020

Antibiotic administration reduces the rate of intraamniotic inflammation in preterm prelabor rupture of the membranes.

Am J Obstet Gynecol 2020 07;223(1):114.e1-114.e20

Perinatology Research Branch, Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, and Detroit, MI; Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI; Department of Obstetrics and Gynecology, University Hospital Hradec Kralove, Charles University, Faculty of Medicine, Hradec Kralove, Czech Republic.

Background: Preterm prelabor rupture of the membranes (PPROM) is frequently complicated by intraamniotic inflammatory processes such as intraamniotic infection and sterile intraamniotic inflammation. Antibiotic therapy is recommended to patients with PPROM to prolong the interval between this complication and delivery (latency period), reduce the risk of clinical chorioamnionitis, and improve neonatal outcome. However, there is a lack of information regarding whether the administration of antibiotics can reduce the intensity of the intraamniotic inflammatory response or eradicate microorganisms in patients with PPROM. Read More

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Correlations between dental wear and oral cavity characteristics: Mandibular torus, palatine torus, and oral exostoses.

Loren R Lease

Am J Hum Biol 2021 03 14;33(2):e23446. Epub 2020 Jun 14.

Department of Sociology, Anthropology and Gerontology, Youngstown State University, Youngstown, Ohio, USA.

Objective: This study evaluates the correlations amongst mandibular torus, palatine torus, oral exostoses to dental wear/loss and temporomandibular damage.

Methods: The sample consists of 504 skulls from the Hamann-Todd Osteological Collection; 223 African American and 281 European Americans aged between 30 and 80 years. The sample was analyzed using Pearson's Chi-square for significance of sex, age, ancestry, and wear as well as the interactions between the demographic variables and the presence of mandibular torus, palatine torus and oral exostoses. Read More

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