Childs Nerv Syst 2021 02 21;37(2):529-538. Epub 2020 Aug 21.
Department of Paediatric Neurosurgery, Great Ormond Street Hospital for Children, NHS Trust, Great Ormond Street, London, WC1N3JH, UK.
Introduction: An open neural tube defect (ONTD) features an exposed, unclosed neural plate in the form of an expanded, flat, and frequently hefty neural placode. Traditional philosophy of ONTD repair aims at preserving function at any cost, which often means stuffing the entire thick and unwieldy but non-functional placode into a tight dural sac, increasing the likelihood of future tethering of the spinal cord. The same philosophy of attempting to save the whole perimetry of the placode also sometimes leads to inadvertent inclusion of parts of the squamous epithelial membrane surrounding the placode into the reconstructed product, only to form inclusion dermoid cyst causing further injury to the neural tissues. Read More