8,606 results match your criteria cau 1296t

Accumulation of sulfamethazine and ciprofloxacin on grain surface decreases the transport of biochar colloids in saturated porous media.

J Hazard Mater 2021 Apr 21;417:125908. Epub 2021 Apr 21.

College of Land Science and Technology, China Agricultural University, Beijing 100193, China. Electronic address:

The increasing amount of antibiotics entering the environment through manure usage and sludge application from wastewater treatment plants (WWTP) attracts much concern due to their potential threat to ecological security and human health. When biochar, a soil and water amendment, is introduced into the soil for remediation, the antibiotics are usually co-present with the biochar colloids (BC) or pre-accumulated in soils. However, little is known about the effect of antibiotics on the behavior of BC. Read More

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LjaFGD: Lonicera japonica functional genomics database.

J Integr Plant Biol 2021 May 13. Epub 2021 May 13.

Guizhou University of Traditional Chinese Medicine, Guizhou, 550025, China.

Lonicera japonica Thunb. a traditional Chinese herb, has been used for treating human diseases for thousands of years. Recently, the genome of L. Read More

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S-acylation of P2K1 mediates extracellular ATP-induced immune signaling in Arabidopsis.

Nat Commun 2021 May 12;12(1):2750. Epub 2021 May 12.

Division of Biochemistry, C.S. Bond Life Science Center, University of Missouri, Columbia, MO, USA.

S-acylation is a reversible protein post-translational modification mediated by protein S-acyltransferases (PATs). How S-acylation regulates plant innate immunity is our main concern. Here, we show that the plant immune receptor P2K1 (DORN1, LecRK-I. Read More

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Coexistence of and in Campylobacter.

mSphere 2021 May 12;6(3). Epub 2021 May 12.

Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, Beijing Laboratory of Food Quality and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China

Previous studies indicated that has developed several mechanisms that confer resistance to florfenicol, which is used in food animal production. This study describes the coexistence of and in and isolates from pigs and poultry. Moreover, whole-genome sequencing data showed that the two genes are located in various multidrug resistance genomic islands within different regions of the genomes. Read More

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Sensitive Near-Infrared Refractive Index Sensors Based on D-Shaped Photonic Crystal Fibers.

J Nanosci Nanotechnol 2021 Nov;21(11):5535-5541

University of Science and Technology of Hanoi, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, 100000, Vietnam.

We report a numerical study of D-shaped photonic crystal fiber based plasmonic refractive index sensor with high resolution and sensitivity in the near-infrared region. D-shaped photonic crystal fiber is formed by side polishing one part of photonic crystal fiber. It has a polishing surface where plasmonic gold layer is coated to modulate the resonant wavelength and enhance the refractive index sensitivity. Read More

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November 2021

Highly variable chloroplast genome from two endangered Papaveraceae lithophytes and .

Ecol Evol 2021 May 19;11(9):4158-4171. Epub 2021 Mar 19.

Institute of Medicinal Plant Development Chinese Academy of Medical Sciences & Peking Union Medical College Key Lab of Chinese Medicine Resources Conservation State Administration of Traditional Chinese Medicine of the People's Republic of China Beijing China.

The increasingly wide application of chloroplast (cp) genome super-barcode in taxonomy and the recent breakthrough in cp genetic engineering make the development of new cp gene resources urgent and significant. is recognized as the most genotypes complicated and taxonomically challenging plant taxa in Papaveraceae. However, there currently are few reports about cp genomes of the genus . Read More

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Proteome-Wide Chromatin Interactomics to Study Plant Epigenetics.

Trends Plant Sci 2021 May 8. Epub 2021 May 8.

KAUST Environmental Epigenetics Program, Division of Biological Environmental Sciences and Engineering, King Abdullah University of Science and Technology, 23955-6900, Thuwal, Saudi Arabia. Electronic address:

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Recent advances in tuning the expression and regulation of genes for constructing microbial cell factories.

Biotechnol Adv 2021 May 8:107767. Epub 2021 May 8.

School of Integrative Engineering, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul 06974, Republic of Korea. Electronic address:

To overcome environmental problems caused by the use of fossil resources, microbial cell factories have become a promising technique for the sustainable and eco-friendly development of valuable products from renewable resources. Constructing microbial cell factories with high titers, yields, and productivity requires a balance between growth and production; to this end, tuning gene expression and regulation is necessary to optimise and precisely control complicated metabolic fluxes. In this article, we review the current trends and advances in tuning gene expression and regulation and consider their engineering at each of the three stages of gene regulation: genomic, mRNA, and protein. Read More

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Gender differences in food allergy depend on the PPAR γ/NF-κB in the intestines of mice.

Life Sci 2021 May 8:119606. Epub 2021 May 8.

Key Laboratory of Precision Nutrition and Food Quality, Key Laboratory of Functional Dairy, Ministry of Education, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, PR China. Electronic address:

Aims: Epidemiology shows that gender affects the incidence of food allergy. However, there is a lack of evidence of gender differences in food allergies and little is known about the mechanisms. The aim of this study was to excavate potential reasons for gender differences in food allergy based on estrogen. Read More

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Improving radiologist's ability in identifying particular abnormal lesions on mammograms through training test set with immediate feedback.

Sci Rep 2021 May 10;11(1):9899. Epub 2021 May 10.

Faculty of Medicine and Health, The University of Sydney, Level 7 - D18, Susan Wakil Health Building, Sydney, NSW, 2006, Australia.

It has been shown that there are differences in diagnostic accuracy of cancer detection on mammograms, from below 50% in developing countries to over 80% in developed world. One previous study reported that radiologists from a population in Asia displayed a low mammographic cancer detection of 48% compared with over 80% in developed countries, and more importantly, that most lesions missed by these radiologists were spiculated masses or stellate lesions. The aim of this study was to explore the performance of radiologists after undertaking a training test set which had been designed to improve the capability in detecting a specific type of cancers on mammograms. Read More

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The genetic mechanism of heterosis utilization in maize improvement.

Genome Biol 2021 May 10;22(1):148. Epub 2021 May 10.

National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan, 430070, China.

Background: In maize hybrid breeding, complementary pools of parental lines with reshuffled genetic variants are established for superior hybrid performance. To comprehensively decipher the genetics of heterosis, we present a new design of multiple linked F1 populations with 42,840 F1 maize hybrids, generated by crossing a synthetic population of 1428 maternal lines with 30 elite testers from diverse genetic backgrounds and phenotyped for agronomic traits.

Results: We show that, although yield heterosis is correlated with the widespread, minor-effect epistatic QTLs, it may be resulted from a few major-effect additive and dominant QTLs in early developmental stages. Read More

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Detection of chlorophyll fluorescence parameters of potato leaves based on continuous wavelet transform and spectral analysis.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Apr 2;259:119768. Epub 2021 Apr 2.

Key Laboratory of Modern Precision Agriculture System Integration Research, Ministry of Education, China Agricultural University, Beijing 100083, China. Electronic address:

The tuber development and nutrient transportation of potato crops are closely related to canopy photosynthesis dynamics. Chlorophyll fluorescence parameters of photosystem II, especially the maximum quantum yield of primary photochemistry (Fv/Fm), are intrinsic indicators for plant photosynthesis. Rapid detection of Fv/Fm of leaves by spectroscopy method instead of time-consuming pulse amplitude modulation technique could help to indicate potato development dynamics and guide field management. Read More

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Nervione, a new benzofuran derivative from .

Nat Prod Res 2021 May 10:1-7. Epub 2021 May 10.

Department of Chemistry, Ho Chi Minh City University of Education, Ho Chi Minh City, Vietnam.

A new benzofuran derivative, nervione (), was isolated from (Blume) Schltr. (Orchidaceae). Eight previously reported compounds were also isolated: 5,7-dimethoxyflavone (2), 3,5,7-trimethoxyflavone (3), 7-methoxyflavone (4), 3,7-dimethoxy-5-hydroxyflavone (5), tetramethylscutellarein (4',5,6,7-tetramethoxyflavone) (6), 5,7-dimethoxy-4'-hydroxyflavone (7), rhamnetin (8), and 5,7-dihydroxy-3',4'-dimethoxyflavone (9). Read More

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Synthesis of messagenin and platanic acid chalcone derivatives and their biological potential.

Nat Prod Res 2021 May 10:1-10. Epub 2021 May 10.

Organic Chemistry, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.

The chalcone derivatives of 20-oxo-lupanes have been synthesised and screened for some types of biological activity. Ozonolysis of lupanes afforded 20-oxo-derivatives with the following condensation using different aromatic aldehydes by Claisen‒Schmidt reaction to the target compounds. The configuration of 19-[3-(pyridin-3-yl)-prop-2-en-1-one]-fragment was established by X-ray analysis. Read More

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Structural feature of TRAFs, their related human diseases and therapeutic intervention.

Hyun Ho Park

Arch Pharm Res 2021 May 10. Epub 2021 May 10.

College of Pharmacy, Chung-Ang University, Seoul, 06974, Republic of Korea.

Several studies have been conducted over the years to unravel the structural information on the receptors that bind to tumor necrosis factor receptor-associated factor (TRAF) and the driving forces for the TRAF/receptor complex. In addition, studies have also been performed to highlight the influence of TRAF malfunctioning and mutations on the development of human disease. However, a holistic study that systematically summarizes the available information and the existing clinical trends towards development of the TRAF-targeting drugs has not been conducted to date. Read More

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Overexpression of Toll-like receptor 4 contributes to the internalization and elimination of Escherichia coli in sheep by enhancing caveolae-dependent endocytosis.

J Anim Sci Biotechnol 2021 May 10;12(1):63. Epub 2021 May 10.

Beijing Key Laboratory for Animal Genetic Improvement, National Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, College of Animal Science and Technology, China Agricultural University, Beijing, China.

Background: Gram-negative bacterial infections have a major economic impact on both the livestock industry and public health. Toll-like receptor 4 (TLR4) plays a crucial role in host defence against Gram-negative bacteria. Exploring the defence mechanism regulated by TLR4 may provide new targets for treatment of inflammation and control of bacterial infections. Read More

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Endocrine disrupting potential of veterinary drugs by in vitro stably transfected human androgen receptor transcriptional activation assays.

Environ Pollut 2021 Apr 30;286:117201. Epub 2021 Apr 30.

Department of Food Science and Biotechnology, Chung-Ang University, Anseong, 17546, Republic of Korea. Electronic address:

We describe the androgen receptor (AR) agonistic/antagonistic effects of 140 veterinary drugs regulated in Republic of Korea, by setting maximum residue limits. It was conducted using two in vitro test guidelines of the Organization for Economic Cooperation and Development (OECD)-the AR-EcoScreen AR transactivation (TA) assay and the 22Rv1/MMTV_GR-KO AR TA assay. These were performed alongside the AR binding affinity assay to confirm whether their AR agonistic/antagonistic effects are based on the binding affinity to AR. Read More

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Epsilon-poly-l-lysine (ε-PL) exhibits multifaceted antifungal mechanisms of action that control postharvest Alternaria rot.

Int J Food Microbiol 2021 May 4;348:109224. Epub 2021 May 4.

College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, PR China. Electronic address:

ε-Poly-l-lysine (ε-PL) is a natural antimicrobial poly-cationic peptide widely applied as a natural preservative in the food industry, whereas its application in preventing postharvest loss of fruit was largely absent. This study investigated the antifungal activity of ε-PL and determined the possible mechanisms involved. The in vivo results indicated that 500 mg L exogenous ε-PL treatment significantly inhibited black spot rot in apple, jujube, and tomato. Read More

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Vitamin D receptor and 1α-hydroxylase are highly expressed in lungs of mice infected with H9N2 avian influenza viruses.

J Steroid Biochem Mol Biol 2021 May 10;211:105907. Epub 2021 May 10.

Department of Pathophysiology, College of Veterinary Medicine, China Agricultural University, Beijing, China. Electronic address:

The H9N2 avian influenza viruses infect poultry worldwide, and can potentially cause a human pandemic without adaptation. Vitamin D3 (D3) is increasingly being recognized for its extra-skeletal roles, such as the inflammatory and immune responses to infection. The aim of this study was to analyze the changes in vitamin D metabolizing enzymes and vitamin D receptor (VDR) in the lung tissues of mice infected with H9N2. Read More

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Genome-wide association study reveals novel loci associated with feeding behavior in Pekin ducks.

BMC Genomics 2021 May 8;22(1):334. Epub 2021 May 8.

National Engineering Laboratory for Animal Breeding and Key Laboratory of Animal Genetics, Breeding and Reproduction, MARA; College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.

Background: Feeding behavior traits are an essential part of livestock production. However, the genetic base of feeding behavior traits remains unclear in Pekin ducks. This study aimed to determine novel loci related to feeding behavior in Pekin ducks. Read More

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iTRAQ-based quantitative proteomic analyses the cycle chronic heat stress affecting liver proteome in yellow-feather chickens.

Poult Sci 2021 Mar 17;100(6):101111. Epub 2021 Mar 17.

College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, China.

Heat stress (HS) is one of the main environmental factors affecting the efficiency of poultry production. The yellow-feather chickens (YFC) as an indigenous strain of chicken is a popular poultry breed in China. Our previous study used the RNA-seq to analyze the gene expression profiles of male YFC under HS and showed that the lipid and energy metabolism pathways are activated in livers of YFC exposed to acute HS (38°C, 4 h and 25°C recovery 2 h). Read More

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Enhancing osteogenesis of adipose-derived mesenchymal stem cells using gold nanostructure/peptide-nanopatterned graphene oxide.

Colloids Surf B Biointerfaces 2021 Apr 29;204:111807. Epub 2021 Apr 29.

School of Integrative Engineering, Chung-Ang University, Seoul, Republic of Korea; Integrative Research Center for Two-Dimensional Functional Materials, Institute of Interdisciplinary Convergence Research, Chung-Ang University, Seoul, Republic of Korea. Electronic address:

Graphene derivatives are highly promising materials for use in stem-cell-based regenerative therapies, particularly for bone regeneration. Herein, we report a graphene oxide (GO)-based hybrid platform (GOHP) that is highly effective for guiding the osteogenesis of human adipose-derived mesenchymal stem cells (hAMSCs). A GO-coated indium tin oxide (ITO) substrate was electrochemically modified with Au nanostructures (GNSs), following which a cysteine-modified quadruple-branched arginine-glycine-aspartic acid was self-assembled on the ITO-GO-GNS hybrid via Au-S bonds. Read More

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Devosia aurantiaca sp. nov., Isolated from Mountain Soil and Proposal of Albitalea gen. nov. to Replace the Illegitimate Prokaryotic Genus Name Geomonas Khan et al. 2020.

Curr Microbiol 2021 May 7. Epub 2021 May 7.

Department of Life Science, Chung-Ang University, 84, HeukSeok-Ro, Dongjak-Gu, Seoul, 06974, Republic of Korea.

Strain H239, a gram-negative, strictly aerobic, and oxidase-positive, and catalase-negative bacterium, was isolated from mountain soil in Gangwon-do of South Korea. Colonies were orange colored, and cells were motile rods with a single polar flagellum. Growth was observed between 25 and 30 °C (optimum, 30 °C), between pH 7. Read More

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Multidimensional analysis of the epigenetic alterations in toxicities induced by mycotoxins.

Food Chem Toxicol 2021 May 4;153:112251. Epub 2021 May 4.

Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing, 100083, China. Electronic address:

Mycotoxins contaminate all types of food and feed, threatening human and animal health through food chain accumulation, producing various toxic effects. Increasing attention is being focused on the molecular mechanism of mycotoxin-induced toxicity in all kinds of in vivo and in vitro models. Epigenetic alterations, including DNA methylation, non-coding RNAs (ncRNAs), and protein post-translational modifications (PTMs), were identified as being involved in various types of mycotoxin-induced toxicity. Read More

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Results of the Optimune trial: A randomized controlled trial evaluating a novel Internet intervention for breast cancer survivors.

PLoS One 2021 7;16(5):e0251276. Epub 2021 May 7.

Leibniz Research Centre (IfADo), Technical University of Dortmund, Dortmund, Germany.

Introduction: After the acute treatment phase, breast cancer patients often experience low quality of life and impaired mental health, which could potentially be improved by offering cognitive behavioural therapy (CBT) and addressing exercise and dietary habits. However, CBT and other behavioural interventions are rarely available beyond the acute treatment phase. Internet-based interventions could bridge such treatment gaps, given their flexibility and scalability. Read More

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Comparative Analysis of Core and Accessory Genes in Coexpression Network.

Methods Mol Biol 2021 ;2242:45-58

State Key Laboratory of Agrobiotechnology, and College of Biological Sciences, China Agricultural University, Beijing, China.

Prokaryotes harbor a various proportion of accessory genes in their genomes. The integration of accessory functions with the core regulation network is critical for environmental adaptation, particularly considering a theoretically unlimited number of niches on the earth for microorganisms. Comparative genomics can reveal a co-occurrence pattern between a subset of accessory genes (or variations in core genes) and an adaptation trait, while comparative transcriptomics can further uncover whether a coordinated regulation of gene expression is involved. Read More

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January 2021

Correction to: Canine parvovirus type 2c in Vietnam continues to produce distinct descendants with new mutations restricted to Vietnamese variants.

Arch Virol 2021 May 7. Epub 2021 May 7.

Immunology Department, Institute of Biotechnology (IBT), Vietnam Academy of Science and Technology (VAST), 18. Hoang Quoc Viet Rd., Cau Giay, Hanoi, Vietnam.

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Anaerobic soil disinfestation with incorporation of straw and manure significantly increases greenhouse gases emission and reduces nitrate leaching while increasing leaching of dissolved organic N.

Sci Total Environ 2021 Apr 24;785:147307. Epub 2021 Apr 24.

Institute for Meteorology and Climate Research (IMK-IFU), Karlsruhe Institute of Technology, Garmisch-Partenkirchen 82467, Germany; State Key Laboratory of Atmospheric Boundary Layer Physics and Atmospheric Chemistry, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029, China.

Greenhouse vegetable production in China mostly involves excessive N fertilization and flood irrigation. This causes serious soil degradation and spreading of soil borne diseases. As a countermeasure against soil borne diseases anaerobic soil disinfestation (ASD) is applied during the summer fallow period. Read More

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Extracellular polymeric substances induced cell-surface interactions facilitate bacteria transport in saturated porous media.

Ecotoxicol Environ Saf 2021 May 3;218:112291. Epub 2021 May 3.

Department of Soil and Water Sciences, China Agricultural University, Beijing 100193, China. Electronic address:

Bacteria often respond to dynamic soil environment through the secretion of extracellular polymeric substances (EPS). The EPS modifies cell surface properties and soil pore-scale hydration status, which in turn, influences bacteria transport in soil. However, the effect of soil particle size and EPS-mediated surface properties on bacterial transport in the soil is not well understood. Read More

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Oocyte-derived microvilli control female fertility by optimizing ovarian follicle selection in mice.

Nat Commun 2021 05 5;12(1):2523. Epub 2021 May 5.

State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, China.

Crosstalk between oocytes and surrounding somatic cells is crucial for mammalian oogenesis, but the structural mechanisms on oocytes to control female reproduction remain unknown. Here we combine endogenous-fluorescent tracing mouse models with a high-resolution live-cell imaging system to characterize oocyte-derived mushroom-like microvilli (Oo-Mvi), which mediate germ-somatic communication in mice. We perform 3D live-cell imaging to show that Oo-Mvi exhibit cellular characteristics that fit an exocrine function for signaling communication. Read More

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