22,351 results match your criteria catalase activities

Lipid profile of sperm cells in Thai native and commercial roosters and its impact on cryopreserved semen quality.

Trop Anim Health Prod 2021 May 14;53(2):321. Epub 2021 May 14.

Department of Animal Science, Faculty of Agriculture, Khon Kaen University, Khon Kaen, Thailand.

Plasma membrane lipids are the key factor in the ability of chicken sperm to be frozen. They ensure fluidity and flexibility of the sperm membrane for effective viability and motility during in vitro storage. The objective of this study was to compare the lipid profiles of different native and commercial chicken breeds: native Thai (Pradu Hang Dam) roosters and commercial (Rhode Island Red) roosters, with respect to their frozen sperm quality. Read More

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Capsaicin protects cardiomyocytes against lipopolysaccharide-induced damage via 14-3-3γ-mediated autophagy augmentation.

Front Pharmacol 2021 27;12:659015. Epub 2021 Apr 27.

Institute of Cardiovascular Diseases, Jiangxi Academy of Clinical Medical Sciences, The First Affiliated Hospital of Nanchang University, Nanchang, China.

The myocardium is susceptible to lipopolysaccharide (LPS)-induced damage in sepsis, and cardiac dysfunction is a leading cause of mortality in patients with sepsis. The changes in cardiomyocyte autophagy in sepsis and the effects and mechanism of action of capsaicin (Cap) remain unclear. The potential pathway of 14-3-3γ-dependent autophagy and the effects and mechanisms of Cap were studied in LPS-induced injury to primary cultured neonatal rat cardiomyocytes. Read More

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3-Acetyldeoxynivalenol induces cell death through endoplasmic reticulum stress in mouse liver.

Environ Pollut 2021 Apr 27;286:117238. Epub 2021 Apr 27.

State Key Laboratory of Animal Nutrition, Department of Animal Nutrition and Feed Science, China Agricultural University, Beijing, 100193, China; Beijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing, 100193, China.

Ingestion of food or cereal products contaminated by deoxynivalenol (DON) and related derivatives poses a threat to the health of humans and animals. However, the toxicity and underlying mechanisms of 3-acetyldeoxynivalenol (3-Ac-DON), an acetylated form of deoxynivalenol, have not been fully elucidated. In the present study, we showed that 3-Ac-DON caused significant oxidative damage, as shown by elevated aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactic dehydrogenase (LDH) in serum, increased lipid peroxidation products, such as hydrogen peroxide (HO) and malondialdehyde (MDA), decreased activities of antioxidant enzymes catalase (CAT) and superoxide dismutase (SOD). Read More

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Foliage application of chitosan alleviates the adverse effects of cadmium stress in wheat seedlings (Triticum aestivum L.).

Plant Physiol Biochem 2021 May 5;164:115-121. Epub 2021 May 5.

School of Resources and Environment, Qingdao Agricultural University, Qingdao, 266109, China. Electronic address:

Excessive cadmium (Cd) causes toxic effects on crops. The effects of chitosan (CTS) with different molecular weight (MW) (5 kDa, 3 kDa, and 1 kDa) on the growth and biochemical parameters, as well as Cd concentrations in Cd-treated wheat plants were examined in a pot experiment. The results demonstrated that foliar spraying with CTS significantly improve the wheat growth, reduce malondialdehyde content and reactive oxygen species accumulation in leaves and decrease Cd concentrations in roots and shoots of wheat seedling under Cd stress. Read More

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A resveratrol-loaded nanostructured lipid carrier hydrogel to enhance the anti-UV irradiation and anti-oxidant efficacy.

Colloids Surf B Biointerfaces 2021 Apr 27;204:111786. Epub 2021 Apr 27.

Department of Pharmaceutics, School of Pharmacy, Fourth Military Medical University, Xi'an, 710032, China; Key Laboratory of Gastrointestinal Pharmacology of Chinese Materia Medica of the State Administration of Traditional Chinese Medicine, Fourth Military Medical University, Xi'an, 710032, China. Electronic address:

Exposure to ultraviolet (UV) irradiation leads to the generation of reactive oxygen species (ROS) and DNA damage in skin tissue, which can further result in skin cancers. Using sunscreens is one of the most popular and the most effective method to resist UV irradiation. Resveratrol (RES) shows high absorbance in UV region and significant anti-oxidant effects. Read More

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Biochemical and metabolic responses of the deep-sea mussel Bathymodiolus platifrons to cadmium and copper exposure.

Aquat Toxicol 2021 May 2;236:105845. Epub 2021 May 2.

Center of Deep Sea Research, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China; Laboratory for Marine Ecology and Environmental Science, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266071, China; CAS Key Laboratory of Marine Ecology and Environmental Sciences, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China; Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao 266071, China; University of Chinese Academy of Sciences, Beijing 10049, China. Electronic address:

Greater interest in commercial deep-sea mining has been accompanied by mounting environmental concerns, including metal contamination resulting from mining activities. However, little is known about the toxic effects of metal exposure on deep-sea life. Given its ability to accumulate metals from the surrounding environment, its wide distribution at both vents and seeps, and its high abundance, the deep-sea mussel Bathymodiolus platifrons could serve as an ideal model to investigate the toxicological responses of deep-sea organisms to metal exposure. Read More

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Antioxidant, histopathological and biochemical outcomes of short-term exposure to acetamiprid in liver and brain of rat: The protective role of N-acetylcysteine and S-methylcysteine.

Saudi Pharm J 2021 Mar 21;29(3):280-289. Epub 2021 Feb 21.

Department of Molecular and Cell Biology, Faculty of Basic Science. University of Mazandaran, Babolsar, Iran.

The present study was conducted to investigate the protective effects of N-Acetyl-L-cysteine (NAC) and S-methyl- L-cysteine (SMC) against hepatic oxidative stress and brain damage induced by acetamiprid (ACP) in rats, which were evaluated by histopathological changes, measuring serum biomarkers and antioxidant defense systems. In this study, 42 rats were randomly divided into 6 groups and administered by intraperitoneally for one week: the control group, the sham group (normal saline), ACP alone (5 mg/kg) (group1), NAC alone (160 mg/kg) (group2), ACP + SMC (100 mg/kg) (group3), ACP + NAC (group 4) and ACP + NAC + SMC (group 5). Our results showed that acetamiprid induces liver injures including infiltration of inflammatory cells, congestion and altered histo-architecture and brain damages including gliosis, hyperemia and necrosis. Read More

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Toxic effects of the dinoflagellate Karenia mikimotoi on zebrafish (Danio rerio) larval behavior.

Harmful Algae 2021 Mar 4;103:101996. Epub 2021 Feb 4.

Wenzhou Key Laboratory of Sanitary Microbiology, Key Laboratory of Laboratory Medicine, Ministry of Education, China, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China 325035. Electronic address:

Karenia mikimotoi is a toxic dinoflagellate that forms harmful blooms in coastal waters, threatening aquaculture worldwide. However, we do not know whether K. mikimotoi has a neurotoxic effect on aquatic animal behavior. Read More

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Rice straw application with different water regimes stimulate enzymes activity and improve aggregates and their organic carbon contents in a paddy soil.

Chemosphere 2021 Jul 15;274:129971. Epub 2021 Feb 15.

Department of Soils and Water Science, Faculty of Agriculture, Benha University, Benha, Qalyubia, Egypt.

Soil organic carbon plays considerable roles in binding soil particles together forming aggregates. Carbon (C) incorporated within these aggregates is thought to be microbially processed; thus, investigating changes in microbial activities i.e. Read More

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The influence on oxidative stress markers, inflammatory factors and intestinal injury-related molecules in Wahui pigeon induced by lipopolysaccharide.

PLoS One 2021 12;16(5):e0251462. Epub 2021 May 12.

College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, Jiangxi, China.

Introduction: The intestinal structure is the foundation for various activities and functions in poultry. An important question concerns the changes in the intestinal status under endotoxin stimulation. This study aimed to investigate the mechanism of intestinal injury induced by lipopolysaccharide (LPS) in Wahui pigeons. Read More

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Combination of donepezil and gallic acid improves antioxidant status and cholinesterases activity in aluminum chloride-induced neurotoxicity in Wistar rats.

Metab Brain Dis 2021 May 12. Epub 2021 May 12.

Department of Biochemistry, Landmark University, PMB, Omu-aran, 1001, Nigeria.

The present study compared the effect of donepezil only and combination of donepezil and gallic acid on oxidative status and cholinesterase activity in the brain of Wistar rats administered AlCl for 60 days. Twenty-eight rats (180 - 200 g) were arbitrarily distributed into four groups of seven animals apiece. Group 1 served as normal control and received distilled water throughout the study. Read More

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Assessment of carbamazepine acute toxicity in the cockle Cerastoderma edule through chemical, physiological and biochemical tools.

Braz J Biol 2021 10;82:e247035. Epub 2021 May 10.

University of Carthage, Laboratory of Biomonitoring of the Environment LR01 ES14, Faculty of Sciences of Bizerte, Zarzouna 7021, Tunisia.

The cockle Cerastoderma edule was exposed to four concentrations (5, 10, 20 and 70 μg L-1) of carbamazepine (CBZ). This anticonvulsant was found to alter the mussel behavior of by reducing its clearance rate (CR). Analysis of CBZ accumulation in tissues of C. Read More

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Comparative evaluation of cardioprotective activity of and juice against isoprenaline-induced cardiotoxicity in rats.

J Complement Integr Med 2021 May 12. Epub 2021 May 12.

Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, India.

Objectives: Comparative evaluation of cardioprotective activity of and juice against isoprenaline induced cardiotoxicity in rats.

Methods: Rats (125-150 g) were orally administered (GA) and (FA) apple juice (3 mL/day, per oral) for 13 days. Myocardial injury was inducted on 14th and 15th day by the administration of Isoprenaline (85 mg/kg/day, subcutaneous). Read More

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Effects of Pseudomonas TCd-1 on rice (Oryza sativa) cadmium uptake, rhizosphere soils enzyme activities and cadmium bioavailability under cadmium contamination.

Ecotoxicol Environ Saf 2021 May 8;218:112249. Epub 2021 May 8.

Fujian Provincial Key Laboratory of Agroecological Processing and Safety Monitoring, School of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China; Key Laboratory of Crop Ecology and Molecular Physiology of Fujian Province, Fujian Agriculture and Forestry University, Fuzhou 350002, China. Electronic address:

Microbial remediation is a promising technique to reduce Cd accumulation in rice (Oryza sativa). In present study, a set of pot experiments were conducted to evaluate the effects of Cd-tolerate Pseudomonas TCd-1 inoculation on rice Cd uptake, soil enzyme activities and Cd bioavailability in the rhizosphere soils under Cd contaminated conditions. The results showed that at the ripening stage, with the inoculation of TCd-1, Cd contents in root, culm, leaf, hull and brown rice significantly reduced by 60. Read More

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Assessment of the effect of long-term exposure to microplastics and depuration period in Sparus aurata Linnaeus, 1758: Liver and blood biomarkers.

Sci Total Environ 2021 May 3;786:147479. Epub 2021 May 3.

Instituto Español de Oceanografía, Centro Oceanográfico de Baleares, Muelle de Poniente s/n, E-07015 Palma de Mallorca, Balearic Islands, Spain. Electronic address:

The constant increase in plastic pollution has attracted great attention in recent years due to its potential detrimental effects on organisms and ecosystems. While the consequences of ingestion of large plastic litter are mostly understood, the impacts resulting from a long-term exposure and a recovery period of microplastics (MPs) are still limited. The aims were to monitor oxidative stress, detoxification and inflammatory biomarkers in liver, plasma and erythrocytes of Sparus aurata exposed during 90 days to low-density polyethylene (LDPE)-MPs enriched diet (10% by weight) followed by 30 days of depuration. Read More

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Fingolimod Potentiates the Antifungal Activity of Amphotericin B.

Front Cell Infect Microbiol 2021 23;11:627917. Epub 2021 Apr 23.

State Key Laboratory of Oncogenes and Related Genes, Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

() is an opportunistic human fungal pathogen that can cause severe infection in clinic. Its incidence and mortality rate has been increasing rapidly. Amphotericin B (AMB), the clinical golden standard antifungal agent, has severe side effects that limit its clinical application. Read More

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Analysing fractions and essential oil for neuroprotective potential against anxiety, depression, and amnesia.

3 Biotech 2021 May 26;11(5):240. Epub 2021 Apr 26.

Department of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, Assam 786004 India.

Scientific pieces of evidence support the pharmacological activity of for its antidepressant, analgesic, anticonvulsant and antioxidant effect. Here, we evaluate the bioactivity of essential oil and the various polarity-based solvent partitioned fractions obtained from for anti-amnesia, anxiolytic and antidepressant activities using Elevated plus maze and Morris water maze models. The cold maceration technique using methanol was adopted for extraction from dried powdered rhizomes and essential oil was extracted by hydrodistillation method. Read More

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Zingiber roseum Rosc. rhizome: A rich source of hepatoprotective polyphenols.

Biomed Pharmacother 2021 May 6;139:111673. Epub 2021 May 6.

Department of Pharmacy, Noakhali Science and Technology University, Sonapur, Noakhali 3814, Bangladesh. Electronic address:

Zingiber roseum is native to Bangladesh and widely used in folk medicine. This present study was designed to assess the ameliorative potential of Zingiber roseum rhizome extract in carbon tetrachloride (CCl) induced hepatotoxicity in mice model. Seven phenolic compounds were identified and quantified by HPLC analysis in the plant extract, including quercetin, myricetin, catechin hydrate, trans-ferulic acid, trans-cinnamic acid, (-) epicatechin, and rosmarinic acid. Read More

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Analysis of Silymarin-Modulating Effects against Acrylamide-Induced Cerebellar Damage in Male Rats: Biochemical and Pathological Markers.

J Chem Neuroanat 2021 May 6:101964. Epub 2021 May 6.

Department of Zoology, Faculty of Science, Alexandria University, Alexandria, Egypt; Department of Biological Sciences, Faculty of Science, Beirut Arab University, Lebanon. Electronic address:

Background: Acrylamide (ACR) is a well-proven neurotoxin and potential food carcinogen in humans and rodent models. Silymarin (SIL) is a flavonoid mixture isolated from seeds, leaves, and fruits of Silymarin marianum (milk thistle) that possesses a free-radical scavenging effect.

Objective: In this work, the primary focus was to investigate the efficacy of SIL to mitigate ACR-induced subacute neurotoxic effects and oxidative changes in rat cerebellum. Read More

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Evaluation of the chemopreventive effects of Hypericum perforatum L on DMBA-applied rat oral mucosa.

Arch Oral Biol 2021 Apr 30;127:105139. Epub 2021 Apr 30.

Ankara University, Faculty of Medicine, Department of Medical Biochemistry, Ankara, Turkey.

Objective: Hypericum perforatum L also known as St. John's wort is known to have many beneficial properties for the organism including its antioxidant and anticancer activities. It is also known to have shown antiproliferative and cytotoxic effects against various cancer cell lines. Read More

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Intracerebroventricular injection of propranolol blocked analgesic and neuroprotective effects of resveratrol following L spinal nerve ligation in rat.

J Complement Integr Med 2021 May 7. Epub 2021 May 7.

Department of Physiology and Medical Physics, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Objectives: Resveratrol as a natural polyphenolic agent can alleviate neuropathic pain symptoms. The mechanism of analgesic activity of resveratrol is far from clear. The current study examine whether analgesic activity of resveratrol is mediated by its neuroprotective and anti-oxidant activity in the neuropathic pain. Read More

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Blue LED causes autophagic cell death in human osteosarcoma by increasing ROS generation and dephosphorylating EGFR.

J Cell Mol Med 2021 May 7. Epub 2021 May 7.

Department of Orthopedics, Department of Pharmacy, The First Affiliated Hospital of Harbin Medical University, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.

Osteosarcoma (OS) is the most common primary malignant bone tumour in adolescence. Lately, light-emitting diodes (LED)-based therapy has emerged as a new promising approach for several diseases. However, it remains unknown in human OS. Read More

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Effect of inhaled anaesthetics gases on cytokines and oxidative stress alterations for the staff health status in hospitals.

Int Arch Occup Environ Health 2021 May 6. Epub 2021 May 6.

Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraidah, Qassim, Saudi Arabia.

Objectives: The present study aimed to evaluate the effects of waste anaesthetic gases on cytokines and oxidative stress of hospital health team members following exposure to waste anaesthetic gases (WAGs).

Subjects And Methods: In total, 180 participants took part in this study; 60 of these were healthy male controls and the 120 participants in the intervention group were staff who work in the operating room. This latter group comprises six occupational subgroups (1) surgeons, (2) surgical assistants, (3) anaesthesiologists (4) anaesthesiology assistants, (5) nurses and (6) janitors. Read More

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The physiological response of Ectomycorrhizal fungus to Cd and Cu stress.

PeerJ 2021 16;9:e11115. Epub 2021 Apr 16.

College of Forestry, Shenyang Agricultural University, ShenYang, People's Republic of China.

Ectomycorrhizal fungi (ECMF) can develop the resistance of host plants to heavy metal stress. However, little is known about the response of ECMF to heavy metal exposure. In this study, the growth and physiological indices of under Cd and Cu stress were studied. Read More

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Microplastic intake and enzymatic responses in Mytilus galloprovincialis reared at the vicinities of an aquaculture station.

Chemosphere 2021 Apr 24;280:130575. Epub 2021 Apr 24.

Instituto Español de Oceanografía, Centro Oceanografico de Baleares, Muelle de Poniente S/n, 07015, Palma de Mallorca, Balearic Islands, Spain.

Aquaculture is a potential source of microplastics (MPs) that could be strong stressors for marine organisms. In this study, we evaluated the effects of MPs derived from aquaculture in antioxidant defences and oxidative stress markers in gills of Mytilus galloprovincialis. Mussels were distributed in three areas with different impacts: inside aquaculture cages, Control 1 (located inside Andratx harbour) and Control 2 (located in a no-anthropized area). Read More

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Caffeic acid protects mice pancreatic islets from oxidative stress induced by multi-walled carbon nanotubes (MWCNTs).

Vet Res Forum 2021 15;12(1):77-85. Epub 2021 Mar 15.

Student Research Committee, Department of Toxicology, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Increasing applications of carbon nanotubes (CNTs) indicate the necessity to examine their toxicity. According to previous studies, CNTs caused oxidative stress that impaired β-cell functions and reduced insulin secretion. Our previous study indicated that single-walled carbon nanotubes (SWCNTs) could induce oxidative stress in pancreatic islets. Read More

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Forsythoside A Alleviates High Glucose-Induced Oxidative Stress and Inflammation in Podocytes by Inactivating MAPK Signaling via MMP12 Inhibition.

Diabetes Metab Syndr Obes 2021 28;14:1885-1895. Epub 2021 Apr 28.

Clinical Research Center for Medical Sciences, IMMU, Chifeng University School of Basic Medical Sciences, Chifeng, Inner Mongolia, 024000, People's Republic of China.

Background: Podocyte injury serves an important role during the progression of diabetic nephropathy (DN). The aim of this study was to investigate the effects of forsythoside A (FA) on high glucose (HG)-induced podocyte injury and to identify the possible mechanisms.

Methods: MPC-5 podocytes were cultured under HG conditions. Read More

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Use of lemongrass essential oil as a feed additive in quail's nutrition: its effect on growth, carcass, blood biochemistry, antioxidant and immunological indices, digestive enzymes and intestinal microbiota.

Poult Sci 2021 Mar 26;100(6):101172. Epub 2021 Mar 26.

Poultry Department, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.

The present study was designed to assess the impact of dietary supplementation of lemongrass essential oil (LGEO) on growth performance, carcass traits, liver and kidney function, immunity, antioxidant indices and caecal microbiota of growing quail. A total of 200 Japanese quails at 1-week-old were haphazardly allotted to 5 groups of 40 chicks in five replicates (8 per replicate). The first group was the control group, while LGEO was added at levels of 150, 300, 450, and 600 mg/kg diet in the 2nd, 3rd, 4th and 5th groups, respectively. Read More

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Impact of citrus flavonoid supplementation on inflammation in lipopolysaccharide-induced periodontal disease in mice.

Food Funct 2021 May 5. Epub 2021 May 5.

Department of Physiology and Pathology, School of Dentistry, São Paulo State University (Unesp), Araraquara, São Paulo, Brazil.

In general, the consumption of flavonoid-rich foods may influence the control/dysregulation of the magnitude and duration of inflammation and oxidative stress, which are known to contribute to multiple pathologies. Information regarding the impact of citrus flavonoid dietary supplementation on periodontal disease is still scarce. Herein, we investigated whether a diet supplemented with eriocitrin and eriodictyol could alter the course of the inflammatory response associated with LPS-induced periodontal disease in mice. Read More

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UV-B exposure and exogenous hydrogen peroxide application lead to cross-tolerance toward drought in Nicotiana tabacum L.

Physiol Plant 2021 May 4. Epub 2021 May 4.

Biosystems Engineering, School of Engineering, Autonomous University of Queretaro-Campus Amazcala, Querétaro, Mexico.

Acclimation of plants to water deficit involves biochemical and physiological adjustments. Here, we studied how UV-B exposure and exogenously applied hydrogen peroxide (H O ) potentiates drought tolerance in tobacco (Nicotiana tabacum L. cv. Read More

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