424 results match your criteria cassia bark


Potency of plant extracts against Penicillium species isolated from different seeds and fruits in Saudi Arabia.

Saudi J Biol Sci 2021 Jun 4;28(6):3294-3302. Epub 2021 Mar 4.

Department of Biochemistry, College of Science, King Saud University, PO Box 22452, Riyadh 11451, Saudi Arabia.

Antifungal activity of extracts of cinnamon (Cinnamomum zeylanicum), Cloves (Syzygium aromaticum), ginger (Zingiber officinale) and turmeric (Curcuma longa) were evaluated against 17 . Seed disease and rotten fruit caused by these species cause considerable loss of quality for different agricultural products. Isolates of spp. Read More

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[Effects of drought stress on physiological and biochemical and chemical components of Cinnamomum cassia seedlings].

Zhongguo Zhong Yao Za Zhi 2021 May;46(9):2158-2166

Guangdong Provincial Southern Medicine Standardized Cultivation and Comprehensive Development Engineering Technology Research Center, Guangzhou Comprehensive Test Station of National Traditional Chinese Medicine Industry Technology System, the Key Laboratory of Lingnan Medicinal Materials Production and Development of the State Administration of Traditional Chinese Medicine, School of Traditional Chinese Medicine, Guangdong Pharmaceutical University Guangzhou 510006, China.

Six month old Cinnamomum cassia seedlings were used to simulate drought stress with polyethylene glycol(PEG 6000). The physiological indicators(osmotic substances, antioxidant enzymes, etc.) and chemical components of seedlings under different drought levels and the correlation between the two were studied. Read More

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2'-Hydroxycinnamaldehyde ameliorates imiquimod-induced psoriasiform inflammation by targeting PKM2-STAT3 signaling in mice.

Exp Mol Med 2021 May 14;53(5):875-884. Epub 2021 May 14.

Department of Biochemistry and Molecular Biology, Chonbuk National University Medical School, Jeonju, Jeonbuk, 54896, Republic of Korea.

2'-Hydroxycinnamaldehyde (HCA), the active component isolated from the stem bark of Cinnamomum cassia, exerts anticancer effects through multiple mechanisms. We recently determined that HCA inhibits signal transducer and activator of transcription 3 (STAT3) signaling in prostate cancer cells. Because STAT3 overactivation has been closely associated with the development of psoriasis, a chronic autoimmune skin disease, we examined whether HCA ameliorates skin lesions in an imiquimod-induced psoriasis-like mouse model. Read More

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Influence of essential oils on sporulation of Eimeria magna oocysts.

Ann Parasitol 2021 ;67(1):11-17

Faculty of Veterinary Medicine, Dnipro State Agrarian and Economic University, Dnipro, Ukraine.

We researched the influence of essential oils from 14 species of plants (Piper cubeba, Cananga odorata, Pelargonium graveolens, Citrus sinensis, Eucalyptus globulus, Lavandula angustifolia, Picea abies, Citrus paradisi, Pterocarpus santalinus, Abies sibirica, Juniperus communis, Melaleuca alternifolia, Syzygium aromaticum and Cinnamomum verum) on the process of sporulation of Eimeria magna Perard, 1925. In the experiment we used 0.5% emulsion of oil during 72 hours, oocysts of E. Read More

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antimicrobial activity of selected essential oils against bacteria and yeasts isolated from the genital tract of mares.

Nat Prod Res 2021 May 5:1-6. Epub 2021 May 5.

Department of Veterinary Science, University of Pisa, Pisa, Italy.

The aim of the present study, the first to test clinical equine isolates, was to evaluate the antimicrobial activity of commercial essential oils (EOs) obtained from and against spp., spp., and spp. Read More

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Exploring combined herbal extract-loaded phytoniosomes for antimalarial and antibacterial activity against methicillin-resistant .

3 Biotech 2021 Apr 19;11(4):177. Epub 2021 Mar 19.

Department of Pharmaceutics, PSG College of Pharmacy, Coimbatore, India.

Antibiotic resistance in the context of treating malarial infections is a major challenge in India. Home remedies such as thulasi leaves (), black pepper seeds (, clove buds (), cinnamon bark (), and nilavembu whole plant powder () were taken to explore antimalarial and methicillin-resistant (MRSA) activity. Among the five extracts, the best two extracts, and extract, showed the presence of Quercetin. Read More

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A novel nutritional mixture, MBN, prevents memory impairment via inhibiting NLRP3 inflammasome formation in 5xFAD transgenic mice.

Nutr Neurosci 2021 Apr 20:1-8. Epub 2021 Apr 20.

Department of Life and Nanopharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul, Republic of Korea.

Objectives: Amyloid beta (Aβ)-induced abnormal neuroinflammation is recognized as a major pathological factor of Alzheimer's disease (AD), which results in memory impairment. Inhibition of excessive neuroinflammation mediated by Aβ is considered a promising strategy to ameliorate AD symptoms. To regulate the inflammatory response, nutritional and dietary supplements have been used for centuries. Read More

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Acute toxicity studies and protective effects of bark extract in streptozotocin-induced diabetic rats.

Drug Chem Toxicol 2021 Apr 13:1-11. Epub 2021 Apr 13.

Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore, India.

The medicinal properties of () bark have been reported for their clinical importance for many diseases including diabetes. However, there is no clear evidence so far regarding dose selection for its hepato- and nephroprotective effect in diabetic condition. Hence, the present study aims at evaluating antioxidant activity, the acute toxicity, and dose fixation of bark for their effective medicinal values in streptozotocin (STZ)-induced rats. Read More

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Anticancer potential of coumarin and its derivatives.

Mini Rev Med Chem 2021 Apr 5. Epub 2021 Apr 5.

Central Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu. Nepal.

Coumarins are found in higher plants like Rutaceae and Umbelliferae and essential oils of cinnamon bark, cassia leaf, and lavender oil. Coumarin compounds show different biological properties viz antimicrobial, antibacterial, antifungal, antioxidant, antitumor, anti-HIV, antihypertension, anticoagulant, anticancer, antiviral, anti-inflammatory, analgesics, antidiabetic, anti-depressive, and other bioactive properties. Coumarin and its derivatives possess anticancer activity against different types of cancers such as prostate, renal, breast, laryngeal, lung, colon, CNS, leukemia, malignant melanoma. Read More

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Cassia Abbreviata Enhances Glucose Uptake and Glucose Transporter 4 Translocation in C2C12 Mouse Skeletal Muscle Cells.

J Evid Based Integr Med 2021 Jan-Dec;26:2515690X211006333

Department of Biomedical Sciences, Tshwane University of Technology, Private Bag Pretoria, South Africa.

Background.: This study aim at assessing aqueous extracts for its potential to exhibit anti-diabetic activity in skeletal muscle cells. In addition to the toxicological and glucose absorption studies, the action of extracts on some major genes involved in the insulin signaling pathway was established. Read More

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The effect of Salaciareticulata, Syzygiumcumini, Artocarpusheterophyllus, and Cassiaauriculata on controlling the rapid formation of advanced glycation end-products.

J Ayurveda Integr Med 2021 Apr-Jun;12(2):261-268. Epub 2021 Mar 14.

Herbal Technology Section (HTS), Industrial Technology Institute (ITI), 363, Bauddhaloka Mawatha, Colombo, 07, Sri Lanka.

Background: The excessive formation of Advanced Glycation End-products (AGEs) by non-enzymatic glycation mediates many health complications in the human body and the formation of AGEs largely accelerated under the hyperglycaemic condition.

Objective: The prospect of the study to assess the strength of inhibiting the rapid AGE formations in four Ayurvedic medicinal plants, namely; Salacia reticulata (stems), Syzygium cumini (barks), Artocarpus heterophyllus (mature leaves) and, Cassia auriculata (flowers).

Materials And Methods: Herbal decoctions of four medicinal plant materials were prepared by simmering with hot water as prescribed by the Ayurvedic medicine. Read More

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Aromatic and Aliphatic Apiuronides from the Bark of .

J Nat Prod 2021 03 8;84(3):553-561. Epub 2021 Mar 8.

Department of Life and Nanopharmaceutical Science, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.

Presl (Cinnamon) has been widely cultivated in the tropical or subtropical areas, such as Yunnan, Fujian, Guandong, and Hainan in China, as well as India, Vietnam, Thailand, and Malaysia. Four new glycosides bearing apiuronic acid (, , , and ) and their sodium or potassium salts (, , and ), together with 31 known compounds, were isolated from a hot water extract of the bark of via repeated chromatography. The structures of the new compounds (-) were determined by NMR, IR, MS, and ICP-AES data and by acid hydrolysis and sugar analysis. Read More

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Chemical composition, antioxidative‎, antibacterial‎‎, and time-kill activities of some selected plant essential oils against foodborne pathogenic and spoilage organisms.

Vet Res Forum 2020 15;11(4):339-346. Epub 2020 Dec 15.

Department of Food Hygiene and Aquaculture, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.

Essential oils (EOs) have been utilized as a growth inhibitor of microorganisms. This study was aimed to recognize the composition, antioxidative‎, antibacterial‎‎‎‎‎‎‎‎, and time-kill activities of , , ; and EOs against O157:H7, and . Gas chromatography-mass spectrometry was used to determine the chemical composition of EOs. Read More

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December 2020

Interstrains comparison of the antimicrobial effect and mode of action of a Vietnamese Cinnamomum cassia essential oil from leaves and its principal component against Listeria monocytogenes.

Lett Appl Microbiol 2021 Jun 23;72(6):757-766. Epub 2021 Mar 23.

Bioingénierie et Dynamique Microbienne aux Interfaces Alimentaires (BioDyMIA, EA n°3733), IUT Lyon 1 site de Bourg en Bresse - Technopole Alimentec, Université de Lyon, Université Claude Bernard, Lyon 1 - ISARA Lyon, rue Henri de Boissieu, Bourg en Bresse, France.

The antibacterial activity of a Cinnamomum cassia essential oil (EO) and of its main component trans-cinnamaldehyde (90% w/w) was examined against five Listeria monocytogenes strains. The minimal inhibitory concentrations (MICs) of C. cassia EO against the five L. Read More

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Microdesigned Nanocellulose-Based Flexible Antibacterial Aerogel Architectures Impregnated with Bioactive .

ACS Appl Mater Interfaces 2021 Feb 19;13(4):4874-4885. Epub 2021 Jan 19.

Shaanxi Provincial Key Laboratory of Papermaking Technology and Specialty Paper Development, College of Bioresources Chemical and Materials Engineering, Shaanxi University of Science & Technology, Xi'an, Shaanxi 710021, PR China.

This work is strategically premeditated to study the potential of a herbal medicinal product as a natural bioactive ingredient to generate nanocellulose-based antibacterial architectures. In situ fibrillation of purified cellulose was done in cinnamon extract (E) to obtain microfibrillated cellulose (MFC). To this MFC suspension, carboxylated cellulose nanocrystals (cCNCs) were homogeneously mixed and the viscous gel thus obtained was freeze-dried to obtain lightweight and flexible composite aerogel architectures impregnated with E, namely, MFC/cCNCs. Read More

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February 2021

Network pharmacology-based research uncovers cold resistance and thermogenesis mechanism of Cinnamomum cassia.

Fitoterapia 2021 Mar 31;149:104824. Epub 2020 Dec 31.

Department of Life Science and Biochemistry, Shenyang Pharmaceutical University, Shenyang 110016, China; Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang 110840, China. Electronic address:

Background: Cinnamomum cassia (L.) J.Presl (Cinnamon) was known as a kind of hot herb, improved circulation and warmed the body. Read More

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The Effect of Plant Additives on the Stability of Polyphenols in Dried Black Chokeberry () Fruit.

Foods 2020 Dec 26;10(1). Epub 2020 Dec 26.

Department of Gastronomy Sciences and Functional Foods, Faculty of Food Science and Nutrition, Poznań University of Life Sciences, Wojska Polskiego 31, 60624 Poznań, Poland.

Chokeberry fruit exhibits a high level of pro-health potential, associated with a significant amount of polyphenol content and antioxidant activity. The fruit is easily perishable and therefore needs to be processed in short order to ensure its availability throughout the year. For this purpose, the fruit is dried, which has an impact on the preservation of bioactive components such as polyphenols. Read More

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December 2020

The complete plastid genome of Chinese cinnamon, Nees (Lauraceae).

Mitochondrial DNA B Resour 2019 Nov 5;4(2):3831-3833. Epub 2019 Nov 5.

Guangdong Provincial Key Laboratory of Silviculture, Protection and Utilization/Guangdong Academy of Forestry, Guangzhou, China.

has long been recognized and cultivated in tropical and subtropical Asia for their aromatic bark to produce cinnamon. We reported for the first time the complete plastid genome of and reconstructed its phylogenetic position. The complete plastid genome is 152,754 bp in length with a quadripartite organization: a large single copy (LSC) region of 93,706 bp and a small single copy (SSC) region of 18,916 bp. Read More

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November 2019

A 12-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial for Evaluation of the Efficacy and Safety of DKB114 on Reduction of Uric Acid in Serum.

Nutrients 2020 Dec 10;12(12). Epub 2020 Dec 10.

Department of Oriental Medicine Biotechnology, Global Campus, Graduate School of Biotechnology and College of Life Sciences, Kyung Hee University, Gyeonggi 17104, Korea.

This study sought to investigate the antihyperuricemia efficacy and safety of DKB114 (a mixture of Linn flower extract and extract) to evaluate its potential as a dietary supplement ingredient. This clinical trial was a randomized, 12-week, double-blind, placebo-controlled study. A total of 80 subjects (40 subjects with an intake of DKB114 and 40 subjects with that of placebo) who had asymptomatic hyperuricemia (7. Read More

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December 2020

Effect of liquid whey protein concentrate-based edible coating enriched with cinnamon carbon dioxide extract on the quality and shelf life of Eastern European curd cheese.

J Dairy Sci 2021 Feb 11;104(2):1504-1517. Epub 2020 Dec 11.

Department of Food Safety and Quality, Veterinary Academy, Lithuanian University of Health Sciences, Tilžės str. 18, LT-47181 Kaunas, Lithuania.

Fresh unripened curd cheese has long been a well-known Eastern European artisanal dairy product; however, due to possible cross-contamination from manual production steps, high moisture content (50-60%), and metabolic activity of present lactic acid bacteria, the shelf life of curd cheese is short (10-20 d). Therefore, the aim of this study was to improve the shelf life of Eastern European acid-curd cheese by applying an antimicrobial protein-based (5%, wt/wt) edible coating. The bioactive edible coating was produced from liquid whey protein concentrate (a cheese production byproduct) and fortified with 0. Read More

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February 2021

How does traditional knowledge of Cassiae semen shed light on weight management? - A classical and modern literature review.

J Ethnopharmacol 2021 Mar 11;268:113572. Epub 2020 Nov 11.

School of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria, Australia. Electronic address:

Ethnopharmacological Relevance: The seed of Senna obtusifolia (L.) H. S. Read More

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Bark extract of Cassia sieberiana DC. (Caesalpiniaceae) displayed good antibacterial activity against MDR gram-negative phenotypes in the presence of phenylalanine-arginine β-naphthylamide.

BMC Complement Med Ther 2020 Nov 12;20(1):342. Epub 2020 Nov 12.

Department of Biochemistry, University of Dschang, P.O. Box 67, Dschang, Cameroon.

Background: Multidrug-resistant (MDR) bacteria remain a major cause of morbidity and mortality globally. The present study was designed to investigate the in vitro antibacterial activities of crude methanol extract and constituents isolated by Column Chromatography (CC) from Cassia sieberiana bark (CSB) against ten MDR Gram-negative bacteria, as well as the mechanisms of action of the most active sample.

Methods: The antibacterial activity of the tested samples (extract, the fractions and their compounds isolated by CC and the structures obtained by exploiting H and C Nuclear magnetic resonance (NMR) spectra) in the presence and absence of an efflux pumps inhibitor, phenylalanine-arginine β-naphthylamide (PAβN), was evaluated using the micro-dilution method. Read More

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November 2020

Activity of Various Essential Oils Against Clinical Dermatophytes of and .

Front Cell Infect Microbiol 2020 16;10:545913. Epub 2020 Oct 16.

Department of Pathology, The Johns Hopkins University School of Medicine, The Johns Hopkins Medical Institutions, Baltimore, MD, United States.

Dermatophytoses account for nearly a quarter of all fungal infections worldwide. These difficult to treat infections of the skin, hair, and nails, are growing more resistant to conventional antifungal treatments, and when treatable, often require prolonged therapeutic regimens. For centuries, essential oils have been used to treat a variety of ailments. Read More

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Encapsulation of essential oils using cinnamic acid grafted chitosan nanogel: Preparation, characterization and antifungal activity.

Int J Biol Macromol 2021 Jan 2;166:902-912. Epub 2020 Nov 2.

Natural Science Department, Federal University of São João del-Rei, Brazil. Electronic address:

Chemical modifications in the chitosan structure may result in obtaining a new material with improved chemical properties, such as an ability to encapsulate lipophilic compounds. This study aimed to synthesize cinnamic acid grafted chitosan nanogel to encapsulate the essential oils of Syzygium aromaticum and Cinnamomum ssp., in order to develop a material to be applied in the control of dermatophytosis caused by the fungus Microsporum canis. Read More

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January 2021

Herbal approach for the management of C0VID-19: an overview.

Drug Metab Pers Ther 2020 Nov 2. Epub 2020 Nov 2.

Department of Basic Medical Sciences, Prince Sultan Military College of Health Sciences, Dhahran, Saudi Arabia.

COVID-19 is the most recently discovered coronavirus infectious disease and leads to pandemic all over the world. The clinical continuum of COVID-19 varies from mild illness with non-specific signs and symptoms of acute respiratory disease to extreme respiratory pneumonia and septic shock. It can transmit from animal to human in the form of touch, through the air, water, utensils, fomite and feco-oral route blood. Read More

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November 2020

Alatains A and B, unique hetero-dimeric polyphenols from Cassia alata and their anti-tobacco mosaic virus activity.

Fitoterapia 2020 Nov 17;147:104763. Epub 2020 Oct 17.

Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan Minzu University, Kunming 650031, PR China. Electronic address:

Two structurally unique polyphenols, alatains A (1) and B (2), were isolated from the bark of Cassia alata. Their structures were elucidated on the basis of spectroscopic analysis. Compounds 1 and 2 represent a new type of hetero-dimeric polyphenols with a C-14-C-5' linkage, biogenetically formed by an unusual intermolecular oxidative phenol-coupling reaction between a chromone unit and an isocoumarin moiety. Read More

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November 2020

Antibacterial activity of Cinnamomum cassia L. essential oil in a carbapenem- and polymyxin-resistant Klebsiella aerogenes strain.

Rev Soc Bras Med Trop 2020 5;53:e20200032. Epub 2020 Oct 5.

Universidade Federal da Grande Dourados, Laboratório de Pesquisa em Ciências da Saúde, Dourados, MS, Brasil.

Introduction: Essential oils can serve as novel sources of antibiotics for multidrug-resistant bacteria.

Methods: The multidrug-resistance profile of a Klebsiella aerogenes strain was assessed by PCR and sequencing. The antibacterial activity of Cinnamomum cassia essential oil (CCeo) against K. Read More

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October 2020

Anti-diabetic and hypolipidemic effects of bark extracts: an , , and approach.

Arch Physiol Biochem 2020 Sep 28:1-11. Epub 2020 Sep 28.

Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore, India.

The present investigation was aimed to study the anti-diabetic and hypolipidemic potential of (Lauraceae family) bark in streptozotocin (STZ)-induced diabetic rats. The preliminary phytochemical analysis (hexane, petroleum ether, chloroform, ethanol, methanol, and aqueous extracts), GC-MS analysis (ethanol), (aqueous, ethanol and methanol), (ethanol) and anti-diabetic activity with hypolipidemic effect of bark was analysed. The ethanolic extract of the bark has a fine inhibitory activity than the aqueous and methanolic extract. Read More

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September 2020

Cinnamomum cassia extract promotes thermogenesis during exposure to cold via activation of brown adipose tissue.

J Ethnopharmacol 2021 Feb 24;266:113413. Epub 2020 Sep 24.

Department of Life Science and Biochemistry, Shenyang Pharmaceutical University, Shenyang, 110016, China; Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang, 110840, China. Electronic address:

Ethnopharmacological Relevance: Cinnamomum cassia (L.) J.Presl (Lauraceae), a widely used traditional Chinese medicine, is well known to exert hot property. Read More

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February 2021

Antibacterial Activity of Essential Oils and Extract against subsp. and for Seed Treatment and Development of a Rapid In Vivo Assay.

Antibiotics (Basel) 2020 Sep 21;9(9). Epub 2020 Sep 21.

CREA-DC Research Centre for Plant Protection and Certification, via C.G. Bertero, 22, 00156 Rome, Italy.

subsp. (Smith) Davis et al. (Cmm) and Yabuuchi et al. Read More

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September 2020