565 results match your criteria cases xanthogranulomatous


Horseshoe Kidney Complicated by Xanthogranulomatous Pyelonephritis in a Young Girl: A Case Report and Review of the Literature.

Acta Medica (Hradec Kralove) 2021 ;64(1):60-63

Institut of Pathology, SRH Wald Klinikum, Gera, Germany.

The cases of horseshoe kidney presented by xanthogranulomatous pyelonephritis are very rare. In this study, the case of XGP developing in HSK in a young female patient was presented due to its rare incidence and the previously reported cases were reviewed, as well. The patient, who has end-stage renal disease and was under treatment, admitted to the clinic for preemptive kidney transplantation. Read More

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January 2021

Xanthogranulomatous pyelonephritis: a focus on microbiological and antibiotic resistance profiles.

BMC Urol 2021 Apr 7;21(1):56. Epub 2021 Apr 7.

Department of Urology, Hospital Universitario Ramón Y Cajal. Instituto Ramón Y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.

Background: Xanthogranulomatous pyelonephritis (XGP) is an inflammatory condition of the kidney and its treatment most often involves a combination of antibiotics and nephrectomy. This study aimed to define the clinical features and management of XGP, focusing on microbiological aspects and antibiotic therapy.

Methods: We performed a retrospective study of 27 cases of XGP diagnosed between January 2001 and January 2020 to analyse their clinical and management characteristics. Read More

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Xantho-granulomatous mastitis preceded by cysts on ultrasound: Two cases with review of literature.

Clin Imaging 2021 Feb 23;78:64-68. Epub 2021 Feb 23.

Department of Radiology, University of Kentucky Chandler Medical Center, 800 Rose St. HX315E, Lexington, KY, USA.

Xantho-granulomatous mastitis (XGM) is a rare entity, only recently described in 2005. These lesions are often biopsied due to their clinical and radiological resemblance to breast cancer. With limited clinical experience, the etiopathogenesis and natural history of XGM remains unknown. Read More

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February 2021

Xanthogranulomatous cholecystitis: Diagnosis and management.

J Visc Surg 2021 Mar 16. Epub 2021 Mar 16.

Department of digestive surgery and liver transplantation, University Hospital Center Croix Rousse, Hospices Civils de Lyon, Claude-Bernard-Lyon-1, 69004 Lyon, France.

Xanthogranulomatous cholecystitis (XGC) is a rare form of cholecystitis, characterized by the presence of xanthogranuloma, prominent yellow structures within the gallbladder wall that is very often lithiasic. When XGC presents in its pseudo-tumoral form with occasional adjacent organ involvement, it can mimic gallbladder carcinoma (GBC). The etiopathogenesis of XGC is inflammatory destruction of Rokitansky-Aschoff sinuses containing biliary and cholesterol pigments within the gallbladder wall; this leads to a florid granulomatous histiocytic inflammatory reaction. Read More

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A case report of complete pathological remission after chemotherapy in a patient with primary renal squamous cell carcinoma.

Transl Androl Urol 2021 Feb;10(2):997-1005

Day Ward of Chemotherapy, Qingdao Central Hospital, Qingdao, China.

This is the first case report of the outcomes of systemic chemotherapy in a patient with locally advanced renal squamous cell carcinoma, a rare tumor, as well as the first next generation sequencing study of this rare tumor. The patient's main symptoms were fever and low back pain. Initial positron emission tomography and computed tomography (PET-CT) suggested a malignant renal tumor at onset, but biopsy confirmed renal squamous cell carcinoma. Read More

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February 2021

[Elevated CA19-9 levels; not always cancer].

Ned Tijdschr Geneeskd 2021 03 2;164. Epub 2021 Mar 2.

Isala, afd. Heelkunde, Zwolle.

Background: The levels of carbohydrate antigen 19-9 (CA19-9) are often tested to stage pancreatobiliary tumours or to monitor the effects of treatment of such tumours. Benign diseases can also be associated with elevated CA 19-9 levels, but extreme elevation is rare in such cases.

Case Description: An 84-year-old man was diagnosed with cholecystitis at the emergency department and received conservative treatment with antibiotics for this. Read More

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Presentation and surgical management of xanthogranulomatous cholecystitis.

Hepatobiliary Pancreat Dis Int 2021 Jan 22. Epub 2021 Jan 22.

First Department of Surgery, Laikon General Hospital, National and Kapodistrian University of Athens, School of Medicine, 17 Ag. Thoma Str. 11527, Athens, Greece.

Background: Xanthogranulomatous cholecystitis (XGC) is a rare benign chronic inflammatory disease of the gallbladder that often presents as cholecystitis and most of the times requires surgical management. In addition, distinguishing XGC from gallbladder cancer preoperatively is still a challenge. The aim of the present systematic review was to outline the clinical presentation and surgical approach of XGC. Read More

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January 2021

Rare squamous cell carcinoma of the kidney with concurrent xanthogranulomatous pyelonephritis: A case report and review of the literature.

Open Med (Wars) 2021 12;16(1):128-133. Epub 2021 Jan 12.

Department of Urology, Mackay Memorial Hospital, Taipei, Taiwan.

Case Presentation: In the current study, we report a 69-year-old female patient who was initially diagnosed with xanthogranulomatous pyelonephritis (XGPN) with nephrolithiasis and a peri-renal abscess. She presented to our department with right flank pain. Physical examination revealed right costovertebral angle knocking pain and computed tomography revealed dilated calyces and one staghorn stone over right kidney, with multiple abscess accumulations over the right peri-renal region. Read More

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January 2021

[A Case of Xanthogranulomatous Cholecystitis That Is Difficult to Distinguish from Advanced Gallbladder Cancer with Invasion of the Transverse Colon].

Gan To Kagaku Ryoho 2021 Jan;48(1):85-87

Dept. of Surgery, Yokote Municipal Hospital.

A 53-year-old woman was admitted to our hospital because of hepatic dysfunction found during a medical checkup. Cholecystitis was suspected, and unenhanced computed tomography (CT) was initially performed because she had bronchial asthma. However, a tumor-like lesion was seen at the bottom of the gallbladder. Read More

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January 2021

Xanthogranulomatous cystitis masquerading as bladder tumor in a child.

Indian J Urol 2020 Oct-Dec;36(4):312-314. Epub 2020 Oct 1.

Department of Pediatric Surgery, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

Xanthogranulomatous cystitis affecting the urinary bladder is extremely rare, and only around thirty adult cases and two pediatric cases have been reported in the literature. The treatment is predominantly surgical as the lesion is mostly infiltrative and mimics malignancy. We report probably the third pediatric case, who presented with symptoms of urinary tract infection and urinary retention and was initially suspected as bladder tumor on imaging. Read More

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October 2020

Acute severe cholecystitis with empyema presenting as a gallbladder mass, jaundice and Mirizzi Syndrome: A case report.

Int J Surg Case Rep 2021 Jan 16;78:223-227. Epub 2020 Dec 16.

Department of General Surgery, The Prince Charles Hospital, Chermside, Brisbane, Queensland, Australia; Faculty of Medicine, The University of Queensland, Herston, Brisbane, Queensland, Australia. Electronic address:

Introduction: Acute severe cholecystitis with empyema presenting as a gallbladder mass, jaundice and Mirizzi Syndrome (MS) is a complex surgical problem both diagnostically and in terms of management as it mimics both xanthogranulomatous cholecystitis (XGC) and gallbladder carcinoma.

Presentation Of Case: A 48-year-old gentleman was referred to us with biliary colic and weight loss with ultrasound findings of gallstones. At subsequent follow-up he became deeply jaundiced with deranged liver function and a CT showing a gallbladder mass and dilated biliary tree. Read More

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January 2021

Adult-Onset Asthma with Periocular Xanthogranuloma (AAPOX), a Variant of Periorbital Xanthogranulomatous Disease: An Uncommon Entity.

Indian Dermatol Online J 2020 Sep-Oct;11(5):792-795. Epub 2020 Sep 19.

Department of Dermatology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

Adult orbital xanthogranulomatous disease (AOXGD) is a rare granulomatous disorder. Adult-onset asthma with periocular xanthogranuloma (AAPOX) which is a subtype of AOXGD is very rare and a realtively unknown entity among dermatologists. Very few cases had been reported in literature. Read More

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September 2020

Xanthogranulomatous cholecystitis: experience in 100 cases.

Ann Transl Med 2020 Sep;8(17):1089

Department of Biliary Surgery, West China Hospital, Sichuan University, Chengdu, China.

Background: Xanthogranulomatous cholecystitis (XGC) is a rare presentation of chronic cholecystitis, characterized by xanthogranuloma, severe foam cells and fibrosis, and can be an inducement of difficulty in cholecystectomy. The purpose of this study was to review the clinical findings and imageology features of XGC and to optimize the treatment option.

Methods: This retrospective study collected clinical symptoms, demographics, imageology, operation records, histopathological findings, and postoperative complications of 100 patients with XGC after evaluating 50005 cholecystectomy specimens between 2009 and 2018 in a single institute. Read More

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September 2020

Angiomyolipoma of the kidney: from simple hamartoma to complex tumour.

Pathology 2021 Jan 31;53(1):129-140. Epub 2020 Oct 31.

Department of Diagnostic and Public Health, Section of Pathology, University of Verona, Verona, Italy; Department of Pathology, Pederzoli Hospital, Peschiera, Italy. Electronic address:

Angiomyolipoma is the most common mesenchymal tumour of the kidney, even if for a long time it has been viewed as a hamartoma rather than a neoplasm. It belongs to a family of neoplasms, named PEComa, characterised by the constant presence of perivascular epithelioid cells that co-express smooth muscle and melanogenesis markers. Angiomyolipoma can occur in patients with tuberous sclerosis, a hereditary syndrome due to the alteration of TSC1 or TSC2 genes, or sporadically. Read More

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January 2021

Laparoscopic subtotal cholecystectomy: comparison of reconstituting and fenestrating techniques.

Surg Endosc 2021 Mar 30;35(3):1014-1024. Epub 2020 Oct 30.

Hepato-Pancreatico-Biliary Surgery, Department of General Surgery, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.

Background: Laparoscopic subtotal cholecystectomy (LSC) is a safe bailout procedure in situations when dissection of "critical view of safety" is not possible. After the proposed classification of subtotal cholecystectomy into "fenestrating" and "reconstituting" techniques in 2016, a comparative review of the outcomes of both methods is timely.

Methods: A literature search of the PubMed, Cochrane Library, and Web of Science database was conducted up to January 31, 2020 for studies that reported LSC. Read More

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Xanthogranulomatous endometritis: a report of two Korean cases with cytologic findings.

J Pathol Transl Med 2020 Nov 23;54(6):513-516. Epub 2020 Oct 23.

Gyeongsang National University College of Medicine, Jinju, Korea.

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November 2020

Xanthogranulomatous cholecystitis: a rare gallbladder pathology from a single-center perspective.

Ann Surg Treat Res 2020 Oct 24;99(4):230-237. Epub 2020 Sep 24.

Department of General Surgery, Faculty of Medicine, Cukurova University, Adana, Turkey.

Purpose: The aim of this study was to review patients with xanthogranulomatous cholecystitis (XGC).

Methods: A total of 79 patients diagnosed with XGC were included in the study. The criteria for XGC in the pathology specimens were the presence of histiocytes, cholesterol deposits, lipids, and focal or widespread wall enlargement. Read More

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October 2020

Minimally invasive nephrectomy for inflammatory renal disease.

Asian J Urol 2020 Oct 14;7(4):345-350. Epub 2019 Sep 14.

Division of Urology, Hospital Universitario San Ignacio, Pontificia Universidad Javeriana, School of Medicine, Bogotá D.C., Colombia.

Objective: Once chronic inflammatory renal disease (IRD) develops, it creates a severe peri-fibrotic process, which makes it a relative contraindication for minimally invasive surgery (MIS). Our objective is to show that laparoscopic nephrectomy (LN) is a surgical option in IRD with fewer complications and better outcomes.

Methods: Retrospective review of patients who underwent a modified-surgical laparoscopic transperitoneal nephrectomy was performed. Read More

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October 2020

Rathke's cleft cyst with xanthogranulomatous change: A case report and review of the literature.

Surg Neurol Int 2020 15;11:246. Epub 2020 Aug 15.

Departments of Neurosurgery, Santa Clara Valley Medical Center, San Jose, California, United States.

Background: Rathke's cleft cysts (RCCs) are benign, typically asymptomatic sellar lesions found incidentally in adults, with a dramatically lower incidence in pediatric patients (<18 years). We present a case of RCC with xanthogranulomatous change (XGC) - an even less common subtype of RCC - treated by endoscopic endonasal surgical resection. This is the second reported instance of an RCC with XGC occurring in a pediatric patient. Read More

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Xanthogranulomatous change in a pleomorphic adenoma: An extremely rare variant/degenerative change. Is it fine needle aspiration induced?

Diagn Cytopathol 2021 Feb 21;49(2):E71-E74. Epub 2020 Aug 21.

Department of Pathology, ESIC Medical College & Hospital, Faridabad, Haryana, India.

Pleomorphic adenoma (PA) is the most common benign salivary gland tumor characterized by morphological diversity, metaplastic changes, degeneration, cystic change, altered differentiation, and rarely malignant transformation, thereby may create a diagnostic dilemma on cytology. Xanthogranulomatous (XG) inflammation within a PA could be due to XG sialadenitis coexistent with PA or preoperative fine-needle aspiration cytology (FNAC) induced histologic alteration. The argument in favor of this hypothesis is that the changes seen in the histopathology would not be present in the cytology, implying that the alterations were most likely due to the traumatic injury of needling rather than spontaneous change of the lesions themselves. Read More

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February 2021

Imaging of Renal Infections and Inflammatory Disease.

Radiol Clin North Am 2020 Sep 14;58(5):909-923. Epub 2020 Jul 14.

Mayo Clinic School of Medicine, Mayo Clinic Hospital, 5777 East Mayo Boulevard, Phoenix, AZ 85054, USA.

Acute pyelonephritis is a bacterial infection of the renal parenchyma and collecting system. Diagnosis is based on clinical findings of fever, flank pain, and urinary tract infection. Computed tomography findings include renal enlargement with wedge-shaped heterogeneous areas of decreased enhancement, known as a "striated nephrogram. Read More

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September 2020

Xanthogranulomatous pyelonephritis due to calculi in a 5-year-old girl.

Turk J Pediatr 2020 ;62(4):690-693

Departments of Pediatric Nephrology, Celal Bayar University, Faculty of Medicine Manisa, Turkey.

Background: Xanthogranulomatous pyelonephritis is characterized by the inflammatory destruction of the renal parenchyma and intensive renal fibrosis. It is named because of its pathological appearance; that of its granulomatous inflammatory process with lipid-laden macrophages, which appear yellow, hence `xantho` which is Greek for yellow. Xanthogranulomatous pyelonephritis is predominantly a disease of adults. Read More

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January 2020

Immunoglobulin G4-related cholecystitis mimicking a locally advanced gallbladder cancer-a case report and review of literature.

Clin J Gastroenterol 2020 Oct 28;13(5):806-811. Epub 2020 Jun 28.

Department of Pathology, Tata Memorial Hospital, Homi Bhabha National Institute (HBNI), Parel, 400012, Mumbai, India.

Immunoglobulin G4 (IgG4)-related disease is a multi-organ immune-mediated condition that can mimic many inflammatory, malignant, and infectious disorders. Isolated IgG4-related cholecystitis without systemic manifestation is extremely rare. We report a rare case of IgG4-related disease with its clinical, radiological and histopathological findings involving only the gallbladder which presented initially as unresectable locally advanced gallbladder cancer on imaging but was diagnosed as IgG4-related cholecystitis preoperatively depending upon serum IgG4 levels and immunohistochemistry. Read More

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October 2020

Atypical focal xanthogranulomatous pyelonephritis without clinical symptoms presenting as infiltrative renal cancer: a case report and literature review.

BMC Urol 2020 Jun 3;20(1):63. Epub 2020 Jun 3.

Department of Urology, First Hospital of Jilin University, Changchun, Jilin, 130021, P.R. China.

Background: Xanthogranulomatous pyelonephritis (XGP) is an uncommon form of chronic pyelonephritis. Most patients of XGP are diffuse in radiology and the clinical features are typical.

Case Presentation: We present a case of 24-year-old female with the absence of symptoms and normal laboratory examinations. Read More

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Xanthogranulomatous epithelial tumor: report of 6 cases of a novel, potentially deceptive lesion with a predilection for young women.

Mod Pathol 2020 10 15;33(10):1889-1895. Epub 2020 May 15.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA.

Epithelial marker expression and/or epithelial differentiation, as well as "anomalous" expression of keratins, are features of some soft tissue tumors. Recently, we have encountered an unusual mesenchymal tumor composed of bland, distinctly eosinophilic, keratin-positive epithelial cells, which were almost entirely obscured by xanthogranulomatous inflammation. Six cases were identified (5 F, 1 M; 16-62 years (median 21 years)) arising in soft tissue (n = 4) and bone (n = 2) and ranging in size from 2 to 7 cm. Read More

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October 2020

Focal Xanthogranulomatous Pyelonephritis in Brachydactyly Mental Retardation Syndrome (2q37 Deletion Syndrome).

J Pediatr Genet 2020 Jun 23;9(2):114-116. Epub 2019 Sep 23.

Department of Paediatric Nephrology, School of Medicine, Manisa Celal Bayar University, Manisa, Turkey.

Xanthogranulomatous pyelonephritis (XGP) is characterized by destruction of the renal parenchyma and granulomatous inflammation with lipid-laden foamy macrophages as well as inflammatory infiltration and intensive renal fibrosis. It generally occurs in adults, especially those in the fifth and sixth decades of life, but is occasionally seen in children as well. Brachydactyly mental retardation (BDMR) syndrome (OMIM 600430) is caused by a small deletion of chromosome 2q37 and is a rare condition, with roughly 100 cases reported worldwide. Read More

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An Important Gallbladder Pathology Mimicking Gallbladder Carcinoma: Xanthogranulomatous Cholecystitis: A Single Tertiary Center Experience.

Surg Laparosc Endosc Percutan Tech 2020 Jun;30(3):285-289

Ministry of Health, University of Health Science, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey.

Background: Xanthogranulomatous cholecystitis (XGC) is an uncommon, focal, or diffuse destructive inflammatory disease of the gallbladder mimicking or being together with the gallbladder carcinoma. This study aimed to evaluate the diagnosis, treatment, and outcomes of patients with XGC as a single tertiary center experience in the light of literature.

Materials And Methods: Data about 34 patients with XGC identified after evaluating 2212 cholecystectomy specimens between January 2013 and December 2018 in a single tertiary center were documented to determine demographics (sex, age), clinical symptoms and findings, biochemical and imaging clues and operative findings, duration of hospitalization, postoperative complications, and histopathologic results. Read More

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Case report: Xanthogranulomatous pyelonephritis masquerading as cystic renal cell carcinoma.

Br J Biomed Sci 2020 Apr 24;77(2):87-90. Epub 2020 Jan 24.

Section of Urology, Department of Surgery, University of Manitoba, Winnipeg, MB, Canada.

Xanthogranulomatous pyelonephritis (XGP) is a rare chronic bacterial inflammation of the renal parenchyma and is often a diagnostic dilemma. We present a challenging case of a patient with XGP. Initially thought to have had renal cell cancer she was treated accordingly with a partial nephrectomy. Read More

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A Rare Case Report on Xanthogranulomatous Osteomyelitis of Hip Mimicking Tuberculosis and Review of Literature.

Cureus 2019 Oct 16;11(10):e5921. Epub 2019 Oct 16.

Orthopedics, Maharishi Markandeshwar University, Ambala, IND.

Xanthogranulomatous osteomyelitis (XO) is a rare chronic inflammatory process characterized by the presence of a large number of lipid-containing macrophages with lymphocytes and plasma cells. We present a case of XO of the hip in a 50-year-old woman with pain in the left hip for 28 months. The patient had a history of taking anti-tuberculosis chemotherapy for five months. Read More

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October 2019

Non-neoplastic Polyps of the Gallbladder: A Clinicopathologic Analysis of 447 Cases.

Am J Surg Pathol 2020 04;44(4):467-476

Department of Pathology, Koç University Hospital.

There is no systematic histopathologic analysis of non-neoplastic polyps in the gallbladder. In this study, in addition to a computer search for cases designated as "polyp," a systematic review of 2533 consecutive routinely sampled archival and 203 totally submitted prospective cholecystectomies were analyzed for >2 mm polyps (cut-off was based on radiologic sensitivity). A total of 447 non-neoplastic polyps were identified. Read More

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