110,621 results match your criteria cases stage


Removal and recovery of heavy metals from sewage sludge via three-stage integrated process.

Chemosphere 2021 Apr 27;280:130650. Epub 2021 Apr 27.

Department of Environmental Engineering, Marmara University, 34722, Goztepe, Istanbul, Turkey. Electronic address:

Heavy metal contamination of sewage sludge is one of the concerns preventing its land application. Traditional processes applied for stabilization of sewage sludge are still inadequate to serve sustainable solutions to heavy metal problem. In this study, fermentation and bioleaching potentials of sewage sludge were investigated in anaerobic reactors for either non-pretreated or ultrasonicated sludge at three different pH regimes (free of pH regulation, acidic, and alkaline). Read More

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Mathematical modeling and numerical simulation of sulfamethoxazole adsorption onto sugarcane bagasse in a fixed-bed column.

Chemosphere 2021 Apr 27;280:130687. Epub 2021 Apr 27.

Center for Environmental Studies, Department of Applied Chemistry and Production Systems, Faculty of Chemical Sciences, University of Cuenca, 010203, Cuenca, Ecuador. Electronic address:

Having rigorous mathematical models is essential for the design and scaling of adsorption columns. In this study, the dynamic behavior of the sulfamethoxazole adsorption on sugarcane bagasse was studied and compared using analytical models and a theoretical mechanistic model. Initially, fixed-bed column tests were carried out at different flow rates and bed heights. Read More

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Pancreaticoduodenectomy for hepatic portal lymph node metastasis after hepatic resection for hepatocellular carcinoma: A clinical case report.

Int J Surg Case Rep 2021 Apr 27;82:105921. Epub 2021 Apr 27.

Center for Pathology and Cytology, Bach Mai Hospital, Viet Nam.

Introduction: In 2018, Hepatocellular carcinoma (HCC) was predicted to be the sixth most commonly diagnosed cancer. Extra-hepatic metastasis due to HCC is a poor prognostic factor, depending on the stage of the disease.

Presentation Of Case: We report a case of a 52-years old male who had undergone Segment 5 (S5) hepatectomy for HCC of 4. Read More

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Clinical characteristics and overall survival prognostic nomogram for oligodendroglioma: a SEER population-based analysis.

World Neurosurg 2021 May 5. Epub 2021 May 5.

Department of medicine, TaikangXianlin Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu 210046, China. Electronic address:

Objective: The aim of this study was to investigate demographics, outcomes, and prognostic factors of all oligodendroglioma cases from the Surveillance, Epidemiology, and End Results (SEER) database and to build a clinical prognosis model for the prediction of survival time for oligodendroglioma patients.

Methods: Cases diagnosed between 1975 and 2016 were selected from the SEER Program. Age, sex, race, insurance, year of diagnosis, marital status, tumor location, tumor size, summary stage, surgery method, and use of radiotherapy and chemotherapy were evaluated with respect to overall survival by univariate and multivariate analysis. Read More

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Prognostic value of preoperative psoas muscle index as a measure of nutritional status in patients with esophageal cancer receiving neoadjuvant therapy.

Nutrition 2021 Mar 6;90:111232. Epub 2021 Mar 6.

First Department of Surgery, Faculty of Medicine University of Yamanashi, Yamanashi, Japan.

Objectives: It has been reported that preoperative nutritional status in some gastrointestinal cancers has a significant effect on postoperative prognosis. However, there are few reports on esophageal cancer, especially for esophageal cancer patients who have undergone neoadjuvant therapy and surgery. Psoas muscle index (PMI) is widely known as an index for assessing preoperative nutritional status, and has recently been reported for its prognostic value in many malignancies. Read More

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Non-tendinous healing after repairing of retracted rotator cuff tear- An Imaging Study.

J Shoulder Elbow Surg 2021 May 5. Epub 2021 May 5.

Department of Orthopaedic Surgery, Myongji Hospital, 697-24 Hwajung-dong, Deokyang-gu, Goyang-si, Gyeonggi-do 412-270, Republic of Korea.

Background: Follow-up magnetic resonance imaging (MRI) after rotator cuff repair can sometimes demonstrate healing with non-tendinous tissue that extends from the footprint to the retracted tendon end, which is inferred as fibrous tissue formation. The aim was to investigate this particular finding and its significance.

Methods: There were 494 eligible cases of healed superior medium- to massive-sized rotator cuff repairs, after the exclusion of re-tears. Read More

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Serum angiopoietin-2 levels in dogs with splenic haemangiosarcoma, haemangioma, and splenitis.

Acta Vet Hung 2021 May 5. Epub 2021 May 5.

2Companion Animal Cancer Research Unit, Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.

Haemangioma (HA) and haemangiosarcoma (HSA) are among the most common splenic neoplasms in dogs. The survival time in splenic HSA is short, probably due to the lack of proper biological markers allowing early detection. We investigated the serum angiopoietin-2 (Ang-2) concentrations in 9 healthy dogs and 40 dogs with abnormal splenic masses. Read More

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Double hindfoot arthrodesis using a single-incision medial approach in the correction of adult-acquired flatfoot deformity: a case series.

Int Orthop 2021 May 8. Epub 2021 May 8.

Head of Foot and Ankle Surgery Group, Orthopaedics and Traumatology Unit, Prevent Senior, São Paulo, Brazil.

Background: Hindfoot arthrodesis is used in patients with advanced-stage acquired flatfoot, usually associated with degenerative joint disease. The objective of the present study was to evaluate the clinical and radiographic results of hindfoot arthrodesis using the single-incision medial approach.

Methods: A case series of 18 consecutive patients undergoing surgical correction between 2015 and 2018 with hindfoot arthrodesis using the medial approach was evaluated. Read More

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Does Training in LI-RADS Version 2018 Improve Readers' Agreement with the Expert Consensus and Inter-reader Agreement in MRI Interpretation?

J Magn Reson Imaging 2021 May 8. Epub 2021 May 8.

Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Background: The Liver Imaging Reporting and Data System (LI-RADS) was established for noninvasive diagnosis for hepatocellular carcinoma (HCC). However, whether training can improve readers' agreement with the expert consensus and inter-reader agreement for final categories is still unclear.

Purpose: To explore training effectiveness on readers' agreement with the expert consensus and inter-reader agreement. Read More

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Post-licensure observational safety study after meningococcal B vaccine 4CMenB (Bexsero) vaccination within the routine UK immunisation program.

Vaccine 2021 May 4. Epub 2021 May 4.

Global Clinical and Epidemiology R&D, GSK, 1101 CL Amsterdam, Netherlands. Electronic address:

The study investigated the safety of 4-component meningococcal serogroup B vaccination (4CMenB) in routine care. 4CMenB exposure and seizures, febrile seizures and Kawasaki disease were identified from The Health Improvement Network (THIN) database of UK electronic primary healthcare records, 2015-2018. A self-controlled case series analysis was completed. Read More

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A new pathological classification of intrahepatic cholangiocarcinoma according to protein expression of SSTR2 and Bcl2.

World J Surg Oncol 2021 May 7;19(1):142. Epub 2021 May 7.

Department of Surgery, Tokushima University, Tokushima, 770-8503, Japan.

Background: No universal classification method for intrahepatic cholangiocarcinoma (IHCC) has been reported based on the embryological origin of biliary epithelial cells. The aim of this study was to classify IHCC according to protein expression levels of somatostatin receptor 2 (SSTR2) and b-cell leukemia/lymphoma 2 (Bcl2) and to elucidate the clinicopathological features of each group.

Methods: Fifty-two IHCC patients who underwent hepatic resection were enrolled in this study. Read More

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Mechanism and risk factors of nausea and vomiting after TACE: a retrospective analysis.

BMC Cancer 2021 May 7;21(1):513. Epub 2021 May 7.

Department of Radiology, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China.

Purpose: The mechanism of postoperative nausea and vomiting after TACE is not clear. This study retrospectively analyzed the patient data to explore the mechanism and risk factors of postoperative nausea and vomiting after TACE.

Materials And Methods: The data of 221 patients who underwent TACE in the interventional department from January 2019 to December 2020 were collected. Read More

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Advanced Adrenocortical Carcinoma: Current Perspectives on Medical Treatment.

Horm Metab Res 2021 May 7;53(5):285-292. Epub 2021 May 7.

Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário Lisboa Norte, Lisbon, Portugal.

Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy. For stage I and II tumors, surgery is a curative option, but even in these cases recurrence is frequent. Practical guidelines advocate a combination of mitotane with etoposide, doxorubicin, and cisplatin as first-line therapy for metastatic adrenocortical carcinoma. Read More

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Unplanned open conversion during radical or partial nephrectomy: Comparing outcomes and trends.

Urology 2021 May 4. Epub 2021 May 4.

Division of Urology, Department of Surgery, Saint Louis University, St Louis, MO. Electronic address:

Objectives: To compare perioperative outcomes between open conversion and planned open surgical approach and to investigate trends.

Materials And Methods: The National Cancer Database (NCDB) was queried for cT1 and cT2 RCC treated by radical (RN) or partial (PN) nephrectomy between 2010 and 2016. We retrospectively analyzed patient demographics, clinical tumor characteristics, and perioperative outcomes between unplanned open conversion and planned open approaches for RN and PN. Read More

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Low-Grade Oncocytic Tumor of Kidney (CK7-Positive, CD117-Negative): Incidence in a Single Institutional Experience with Clinicopathological and Molecular Characteristics.

Hum Pathol 2021 May 4. Epub 2021 May 4.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905. Electronic address:

Aims: Low-grade oncocytic tumor of the kidney (LOT) is characterized by cytoplasmic eosinophilia and a CK7-positive/CD117-negative immunophenotype. Morphologically, they exhibit overlapping features with oncocytoma and chromophobe renal cell carcinoma (chRCC). Our aim was to obtain long-term clinical follow-up data, clinicopathological and molecular characteristics, and incidence of LOT. Read More

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Sperm chromatin integrity in a man with macrocephaly syndrome.

Andrologia 2021 May 7:e14100. Epub 2021 May 7.

Department of Animal Biotechnology, Reproductive Biomedicine Research Center, Royan Institute for Biotechnology, ACECR, Isfahan, Iran.

This study reports chromatin status and ICSI outcomes in a case of sperm macrocephaly syndrome(SMS), showing 100% of spermatozoa with abnormal morphology. Percentages of sperm DNA fragmentation for TUNEL (31.7% versus 6. Read More

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[Revision ACL Reconstruction in Our Study Population].

Acta Chir Orthop Traumatol Cech 2021 ;88(2):124-130

Klinika dětské a dospělé ortopedie a traumatologie 2. lékařské fakulty Univerzity Karlovy a Fakultní nemocnice v Motole, Praha.

INTRODUCTION The authors present the long-term clinical outcomes of revision anterior cruciate ligament (ACL) reconstruction. The aim was to compare the surgical technique with respect to the clinical outcomes within 3 years postoperatively. MATERIAL AND METHODS The clinical evaluation of revision anterior cruciate ligament reconstructions performed at our department in 2002-2017 was carried out. Read More

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January 2021

Sunlight exposure in infancy decreases risk of sporadic retinoblastoma, extent of intraocular disease.

Cancer Rep (Hoboken) 2021 May 7:e1409. Epub 2021 May 7.

Department of Pathology, Hospital Infantil de Mexico, Federico Gomez, Mexico City, Mexico.

Background: Prior ecologic studies suggest that UV exposure through sunlight to the retina might contribute to increased retinoblastoma incidence.

Aims: Our study objectives were (1) to examine the relationship between exposure to sunlight during postnatal retinal development (prior to diagnosis of sporadic disease) and the risk of retinoblastoma, and (2) to examine the relationship between sun exposure during postnatal retinal development, and the extent of disease among children with unilateral and bilateral retinoblastoma.

Methods And Results: We interviewed 511 mothers in the EpiRbMx case-control study about their child's exposure to sunlight during postnatal retinal cell division by examining three time periods prior to Rtb diagnosis coinciding with developmental stages in which outdoor activities vary. Read More

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Requirement of Mental-Health Referral Letters for Staged and Revision Genital Gender-Affirming Surgeries: An Unsanctioned Barrier to Care.

Andrology 2021 May 7. Epub 2021 May 7.

Cedars-Sinai Transgender Surgery and Health Program, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Background: The World Professional Association for Transgender Health (WPATH) recommends referral letters from two mental-health providers within one year of gender-affirming genital surgery (gGAS) to ensure patient readiness before primary surgeries. Many U.S. Read More

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[Ventral penis curvature correction in children with hypospadias].

Urologiia 2021 May(2):74-77

Urological-andrological Department, Russian Childrens Hospital, Moscow, Russia.

Objective: Our study aims to improve hypospadias in children by successfully correcting ventral penile curvature.

Materials And Methods: From 2014 to 2018, 424 patients with ventral penile curvature of 15-60 degrees were treated. All patients were divided into 3 groups depending on the form of hypospadias: Group I consists of 303 patients with subcoronal and midshaft hypospadias; Group II - 48 patients with midshaft hypospadias who earlier underwent urethroplasty; Group III - 73 patients with chordee without hypospadias. Read More

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Promoting Compliance to COVID-19 Vaccination in Military Units.

Mil Med 2021 May 7. Epub 2021 May 7.

Israeli Defense Forces Medical Corps, Affiliated with the Hebrew University of Jerusalem, Tel Hashomer 526000, Israel.

Background: On December 27th, 2020, the Israeli Defense Forces initiated a mass COVID-19 vaccination campaign aiming to vaccinate its personnel. This population upheld specific characteristics in terms of age and sex, lack of significant comorbidities, and a general scarcity of risk factors for sustaining a severe COVID-19 illness. We present the measures taken to increase vaccination compliance, and the vaccination rate that followed these actions. Read More

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Evidence for Transmission of Taeniasis/Cysticercosis in a Rural Area of Northern Rwanda.

Front Vet Sci 2021 20;8:645076. Epub 2021 Apr 20.

Área de Parasitología del Departamento de Agroquímica y Medioambiente, Universidad Miguel Hernández de Elche, Alicante, Spain.

Cysticercosis is a parasitic infection caused by the metacestode larval stage (cysticercus) of . In humans, cysticercosis may infect the central nervous system and cause neurocysticercosis, which is responsible for over 50,000 deaths per year worldwide and is the major cause of preventable epilepsy cases, especially in low-income countries. Cysticercosis infection is endemic in many less developed countries where poor hygiene conditions and free-range pig management favor their transmission. Read More

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Description of a Lung Cancer Hotspot: Disparities in Lung Cancer Histology, Incidence, and Survival in Kentucky and Appalachian Kentucky.

Clin Lung Cancer 2021 Mar 26. Epub 2021 Mar 26.

Markey Cancer Center, University of Kentucky, Lexington, KY; Kentucky Cancer Registry, Markey Cancer Center, University of Kentucky, Lexington, KY; Division of Biomedical Informatics, Department of Internal Medicine, College of Medicine, University of Kentucky, Lexington, KY.

Introduction: Kentucky is recognized as the state with the highest lung cancer burden for more than 2 decades, but how lung cancer differs in Kentucky relative to other US populations is not fully understood.

Patients And Methods: We examined lung cancer reported to the Surveillance, Epidemiology, and End Results (SEER) Program by Kentucky and the other SEER regions for patients diagnosed between 2012 and 2016. Our analyses included histologic types, incidence rates, stage at diagnosis, and survival in Kentucky and Appalachian Kentucky relative to other SEER regions. Read More

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Large-cell neuroendocrine tumor of the prostate: a case report and review of the literature.

J Med Case Rep 2021 May 7;15(1):254. Epub 2021 May 7.

Urology Department, René Dubos Hospital, Pontoise, France.

Background: Primitive neuroendocrine prostate neoplasms are rarely reported. This entity comprises carcinoïd tumors and poorly differentiated neuroendocrine tumors, mainly those of the small-cell type. Large-cell-type primitive tumors are exceptional, and only nine cases are reported in the literature. Read More

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Pathological findings and husbandry management in captive Chrysaora spp. medusae affected by umbrellar ulcerative lesions.

J Invertebr Pathol 2021 May 3:107599. Epub 2021 May 3.

Pathology group, PASAPTA, Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, Av. Seminario s/n, 46113 Moncada, Valencia, Spain. Electronic address:

During a 12 month period, a group of 14 medusa-stage jellies of the genus Chrysaora, including Pacific sea nettle (Chrysaora fuscescens, n=11) and Japanese sea nettle (Chrysaora pacifica, n=3), that were maintained in a public aquarium developed progressive ulcerative umbrellar lesions. In 6 cases (42.9%), ulceration was deep, transmural, and perforated through the mesoglea and subumbrella. Read More

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Primary cytoreductive surgery for advanced stage endometrial cancer: A systematic review and meta-analysis.

Am J Obstet Gynecol 2021 May 3. Epub 2021 May 3.

Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC, USA.

Objective: Endometrial cancer uncommonly presents at an advanced stage, and little prospective evidence exists to guide management. We aimed to summarize evidence on primary cytoreductive surgery (PCS) in the treatment of advanced stage endometrial cancer.

Data Sources: MEDLINE, Embase, and Scopus databases were searched from inception to September 11, 2020, using search terms representing the themes "endometrial cancer," "advanced stage," and "primary cytoreductive surgery". Read More

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Profiling non-small cell lung cancer reveals that PD-L1 is associated with wild type EGFR and vascular invasion, and immunohistochemistry quantification of PD-L1 correlates weakly with RT-qPCR.

PLoS One 2021 6;16(5):e0251080. Epub 2021 May 6.

Department of Pathology, Faculty of Medicine, Dalhousie University Halifax, Nova Scotia, Canada.

Most lung cancer patients are diagnosed at an advanced stage, limiting their treatment options with very low response rate. Lung cancer is the most common cause of cancer death worldwide. Therapies that target driver gene mutations (e. Read More

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[Severe sepsis and retinopathy of prematurity in very low birth weight preterm newborns in a third-level healthcare center in Lima, Peru between 2008 and 2018: A case-control study].

Medwave 2021 Apr 19;21(3):e8157. Epub 2021 Apr 19.

Facultad de Medicina, Universidad Peruana Cayetano Heredia, Lima, Perú. ORCID: 0000-0002-7828-300X.

Background: Retinopathy of prematurity is the leading worldwide cause of visual impairment. There is little available data on its epidemiology and related factors and consequences in developing countries such as Peru. Due to this lack of information, we decided to do this study. Read More

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Clinical features and outcome of MIS-C patients: an experience from Central Anatolia.

Clin Rheumatol 2021 May 6. Epub 2021 May 6.

Department of Pediatric Critical Care, Selcuk University Faculty of Medicine, Konya, Turkey.

Background: Multisystem inflammatory syndrome in children (MIS-C) is a new clinical condition characterized by signs of inflammation and multiorgan dysfunction due to cytokine storm associated with SARS-CoV-2. The clinical spectrum of MIS-C ranges from mild to severe, and even to mortal multisystem involvement. To guide clinicians, we evaluated detailed demographic characteristics, clinical features, laboratory findings, and outcomes of MIS-C cases. Read More

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