186,594 results match your criteria cases presented

A delayed resurgence of respiratory syncytial virus (RSV) during the COVID-19 pandemic: An unpredictable outbreak in a small proportion of children in the Southwest of Iran, April 2022.

J Med Virol 2022 Aug 12. Epub 2022 Aug 12.

Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Background: The global outbreak of Coronavirus Disease 2019 (COVID-19), an emerging disease caused by Severe Acute Respiratory Syndrome Virus-2 (SARS-CoV-2), and strict restrictions implemented to control the infection have impacted the circulation and transmission of common seasonal viruses worldwide and subsequently the rate of hospitalizations in children at young ages. Respiratory syncytial virus (RSV) surprisingly disappeared in 2020-2021 in many countries due to lockdown and precautions were taken because of the COVID-19 pandemic. Herein, we showed a notable change in the rate of hospitalization and reported an unpredictable outbreak of RSV in a small proportion of children admitted to a children's hospital in Dezful (a city in Southwest Iran) in the early spring of 2022. Read More

View Article and Full-Text PDF

Contraction bias in temporal estimation.

Cognition 2022 Aug 9;229:105234. Epub 2022 Aug 9.

School of Psychological Sciences, Tel-Aviv University, Israel; Sagol School of Neuroscience, Tel-Aviv University, Israel. Electronic address:

When asked to compare the perceptual features of two serially presented objects, participants are often biased to over- or under-estimate the difference in magnitude between the stimuli. Overestimation occurs consistently when a) the two stimuli are relatively small in magnitude and the first stimulus is larger in magnitude than the second; or b) the two stimuli are relatively large in magnitude and the first stimulus is smaller in magnitude than the second; underestimation consistently occurs in the complementary cases. This systematic perceptual bias, known as the contraction bias, was demonstrated for a multitude of perceptual features and in various modalities. Read More

View Article and Full-Text PDF

Wide-awake local anesthesia for open rotator cuff repair: A case report.

Int J Surg Case Rep 2022 Aug 9;97:107494. Epub 2022 Aug 9.

Department of Orthopedic Surgery, Clinical Research Development Unit of Shohada-e Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Physiotherapy Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

Introduction And Importance: Improper treatment of rotator cuff tear might result in progression of tear and deterioration of patient function. The rotator cuff tear can be managed conservatively in most cases however surgical treatment is inevitable in persistent patients.

Presentation Of Case: A 45-year-old woman presented to our clinic with shoulder pain and restricted range of motion following a fall from a height three months before the current presentation. Read More

View Article and Full-Text PDF

Carbon Dioxide, Blood Pressure, and Perioperative Stroke: a Retrospective Case-Control Study.

Anesthesiology 2022 Aug 12. Epub 2022 Aug 12.

Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI USA 48109.

Background: The relationship between intraoperative physiology and postoperative stroke is incompletely understood. Preliminary data suggest that either hypo- or hypercapnia coupled with reduced cerebrovascular inflow (e.g. Read More

View Article and Full-Text PDF

Long-term outcome of tibial plateau leveling osteotomy using an antimicrobial silver-based coated plate in dogs.

PLoS One 2022 12;17(8):e0272555. Epub 2022 Aug 12.

Surgery Department, Centre Hospitalier Vétérinaire Aquivet, Eysines, France.

Objectives: To evaluate long-term outcome using the BioMedtrix™ TPLO Curve® plate in dogs with cranial cruciate ligament disease (CrCLd) treated by tibial plateau leveling osteotomy (TPLO).

Study Design: Retrospective case study.

Animals: Dogs (n = 323, 337 stifles). Read More

View Article and Full-Text PDF

HRCT imaging features in representative imported cases of 2019 novel coronavirus pneumonia.

Precis Clin Med 2020 Mar 11;3(1):9-13. Epub 2020 Feb 11.

Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China.

With the spread of novel coronavirus (2019-nCoV) pneumonia, chest high-resolution computed tomography (HRCT) has been one of the key diagnostic tools. To achieve early and accurate diagnostics, determining the radiological characteristics of the disease is of great importance. In this small scale research we retrospectively reviewed and selected six cases confirmed with 2019-nCoV infection in West China Hospital and investigated their initial and follow-up HRCT features, along with the clinical characteristics. Read More

View Article and Full-Text PDF

Synchronous surgery and immediate reconstruction of double primary cancers of the ovary and breast.

Medicine (Baltimore) 2022 Aug;101(32):e29607

Division of Oncology and Surgery, Department of Surgery, Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan.

Introduction: There has been an ongoing debate about the benefits and risks between synchronous surgery and two independent surgery of ovary tumor removal and breast reconstruction. Here we report a synchronous oncological surgery and immediate postmastectomy reconstruction of double primary cancers of the ovary and breast.

Patient Concerns: A 58-year-old woman presented with a right breast lump and ascites. Read More

View Article and Full-Text PDF

Case report of isolated synchronous multiple splenic metastases from rectal cancer: A case report and brief review of the literature.

Medicine (Baltimore) 2022 Aug;101(32):e29613

Department of General Surgery, The Second Hospital of Jilin University, Changchun, Jilin, China.

Introduction: Isolated splenic metastasis emanating from colorectal cancer is an extremely rare finding, which usually indicates widely disseminated and multiple metastatic cancer. There have only been 39 cases of isolated splenic metastasis reported in the English literature to date.

Patient Concerns: An 84-year-old female patient presented to our department with dark-red bloody stool that had persisted for 1 month and with an increased serum carcinoembryonic antigen (CEA) level. Read More

View Article and Full-Text PDF

Bioactive Furanyl- or Thienyl-Substituted Nucleobases, Nucleosides and Their Analogues.

Tomasz Ostrowski

Mini Rev Med Chem 2022 Aug 12. Epub 2022 Aug 12.

Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704 Poznan, Poland.

Five-membered heterocycles, including furan and thiophene, play a prominent role in drug design as structural units of bioactive molecules. This review is intended to demonstrate the importance of the furan-2-yl, furan-3-yl, thien-2-yl and thien-3-yl substituents in medicinal chemistry of purine and pyrimidine nucleobases, nucleosides and selected analogues. Data presented in the article are limited to compounds containing heteroaromatic ring connected through a bond, and not fused to other systems. Read More

View Article and Full-Text PDF

Influences of Bifid Triple Viable Capsules Plus Cetirizine on Gut Microbiota and Immune Function in Children with Eczema.

Drug Des Devel Ther 2022 3;16:2509-2515. Epub 2022 Aug 3.

Pediatrics, First Hospital of Shanxi Medical University, Taiyuan City, People's Republic of China.

Objective: Infantile eczema (IE), a common pediatric allergic skin disease caused by multiple inherent and external factors, is common in infants and young children, with skin lesions and itching as the main clinical manifestations. At present, its pathological mechanism has not been thoroughly clarified, but scholars believe that it is related to the joint action of various internal and external factors. This research aims to investigate the influences of bifid triple viable capsules plus cetirizine (CTZ) on gut microbiota (GMB) and immunity in children with eczema. Read More

View Article and Full-Text PDF

The White Matter Rounds experience: The importance of a multidisciplinary network to accelerate the diagnostic process for adult patients with rare white matter disorders.

Front Neurol 2022 25;13:928493. Epub 2022 Jul 25.

Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC, Canada.

Introduction: Adult genetic leukoencephalopathies are rare neurological disorders that present unique diagnostic challenges due to their clinical and radiological overlap with more common white matter diseases, notably multiple sclerosis (MS). In this context, a strong collaborative multidisciplinary network is beneficial for shortening the diagnostic odyssey of these patients and preventing misdiagnosis. The White Matter Rounds (WM Rounds) are multidisciplinary international online meetings attended by more than 30 physicians and scientists from 15 participating sites that gather every month to discuss patients with atypical white matter disorders. Read More

View Article and Full-Text PDF

Bell's palsy in a patient after contracting COVID-19 with signs of aberrant nerve regeneration.

Am J Ophthalmol Case Rep 2022 Aug 6:101679. Epub 2022 Aug 6.

College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.

Purpose: To report a 56-year-old male in Saudi Arabia who developed signs of aberrant facial nerve regeneration after recovering from Bell's palsy associated with COVID-19 infection.

Observations: The patient presented, months following recovery from Bell's palsy associated with COVID-19, with symptoms of aberrant seventh nerve regeneration in the form of tearing with eating "crocodile tears" and synchronous right eyelid closure with the jaw movement.

Conclusions And Importance: Case reports of Bell's palsy associated with COVID-19 are emerging, but association does not mean causation. Read More

View Article and Full-Text PDF

A rapid, easy, and scalable whole blood monocyte CD169 assay for outpatient screening during SARS-CoV-2 outbreak, and potentially other emerging disease outbreaks.

SAGE Open Med 2022 3;10:20503121221115483. Epub 2022 Aug 3.

Beckman Coulter Life Sciences, Marseille, France.

Objective: The COVID-19 corona virus disease outbreak is globally challenging health systems and societies. Its diagnosis relies on molecular methods, with drawbacks revealed by mass screening. Upregulation of neutrophil CD64 or monocyte CD169 has been abundantly reported as markers of bacterial or acute viral infection, respectively. Read More

View Article and Full-Text PDF

Foreign Body Aspiration in a Child With a Rare Tracheal Bronchus.

Cureus 2022 Jul 10;14(7):e26710. Epub 2022 Jul 10.

Otolaryngology - Head and Neck Surgery, Ohud Hospital, Al-Madinah Al-Munawarah, SAU.

A tracheal bronchus is an unusual bronchial division anomaly in which an accessory bronchus arises from the trachea or main bronchus and travels to the higher lobe territory. This report discusses a case of incidentally diagnosed tracheal bronchus after foreign body removal via bronchoscopy. A one-year-old boy presented to the hospital with cough and noisy breathing after choking on peanuts. Read More

View Article and Full-Text PDF

Adjunctive Treatment with Interferon Alpha 2b in Conjunctival Melanoma.

Ocul Oncol Pathol 2022 Jun 27;8(2):88-92. Epub 2022 Jan 27.

Universitary Hospital Santa Maria, Lleida, Spain.

Purpose: The aim of the study was to demonstrate the clinical outcomes after resection of conjunctival melanoma (CM) followed by topical interferon (IFN) alpha 2b after a long follow-up.

Methods: Two consecutive CM patients were treated using tumor excision followed by topical IFN alpha 2b (1,000,000 UI/mL) four times a day for 12 weeks. The second case presented positivity due to the presence of tumor cells in the lower margin of the resection. Read More

View Article and Full-Text PDF

How effective is indocyanine green (ICG) in localization of malignant pulmonary nodules? A systematic review and meta-analysis.

Front Surg 2022 25;9:967897. Epub 2022 Jul 25.

Department of Thoracic Surgery, Cantonal Hospital Lucerne, Lucerne, Switzerland.

Background: Video-Assisted and Robotic-Assisted techniques become constantly more prominent practice in thoracic surgery for lung cancer. Furthermore, the increased frequency in detection of small lung cancers makes the intra-operative identification of these cancers even more challenging. Indocyanine Green (ICG) is one of the most commonly used dyes that assists surgeons identify small lung cancers intra-operatively. Read More

View Article and Full-Text PDF

A Novel Case of Hyperglycemic Hyperosmolar State After the Use of Teprotumumab in a Patient With Thyroid Eye Disease.

AACE Clin Case Rep 2022 Jul-Aug;8(4):148-149. Epub 2022 Jan 29.

Division of Endocrinology, Stony Brook University Hospital, Renaissance School of Medicine.

Background/objective: Teprotumumab, a novel treatment for thyroid eye disease (TED), which blocks the insulin-like growth factor 1 receptor, has been associated with improvement in proptosis and inflammatory ocular symptoms. In the original trials, hyperglycemia was reported in 5% to 12% of patients; however, none required hospitalization. We report a case of hyperglycemic hyperosmolar state after the first infusion of teprotumumab. Read More

View Article and Full-Text PDF
January 2022

Patterns of Clinical Reactivity in a Danish Cohort of Tree Nut Allergic Children, Adolescents, and Young Adults.

Front Allergy 2022 28;3:824660. Epub 2022 Mar 28.

Allergy Clinic, Department of Dermatology and Allergy, Copenhagen University Hospital, Gentofte, Denmark.

Background: Tree nut allergy is associated with severe reactions and poly-sensitization to other nuts and peanuts often occurs. There are regional differences in sensitization profiles that result in differences in clinical presentation. Denmark is located in a birch pollen endemic area, which could influence the allergy patterns due to pollen cross-sensitization. Read More

View Article and Full-Text PDF

Machine learning in the loop for tuberculosis diagnosis support.

Front Public Health 2022 26;10:876949. Epub 2022 Jul 26.

Subred Integrada de Servicios de Salud Centro Oriente E.S.E, Bogotá, Colombia.

The use of machine learning (ML) for diagnosis support has advanced in the field of health. In the present paper, the results of studying ML techniques in a tuberculosis diagnosis loop in a scenario of limited resources are presented. Data are analyzed using a tuberculosis (TB) therapy program at a health institution in a main city of a developing country using five ML models. Read More

View Article and Full-Text PDF

Aortic root replacement in bicuspid versus tricuspid aortic valve patients.

Ann Cardiothorac Surg 2022 Jul;11(4):436-447

University Department for Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.

Background: Concomitant replacement of the aortic root and aortic valve is a widely used treatment strategy in elective patients with aortic valve stenosis and root aneurysm. It is also a strategy frequently employed in patients with acute aortic dissection type A (AADA), involving the aortic root. Although more patients have undergone valve sparing procedures over the past decades, the classic 'modified Bentall technique' remains a valid option, particularly for patients with a bicuspid aortic valve (BAV). Read More

View Article and Full-Text PDF

Diagnostic value of cardiac magnetic resonance imaging for myocardial fibrosis in patients with heart failure and its predictive value for prognosis.

Am J Transl Res 2022 15;14(7):4657-4665. Epub 2022 Jul 15.

Medical Imaging Center, The First People's Hospital of Shangqiu City No. 292, Kai Xuan Nan Road, Shangqiu 476100, Henan, China.

Objective: To determine the diagnostic value of cardiac magnetic resonance imaging (CMRI) for myocardial fibrosis (MF) in patients with heart failure (HF) and its predictive value for prognosis.

Methods: A total of 180 patients with heart failure who were hospitalized in the Cardiology Department of The First People's Hospital of Shangqiu City from September 2019 to May 2021 were selected and assigned to Group B (n=80) given levosimendan and Group A (n=100) given levosimendan combined with ivabradine hydrochloride. The cardiac function indicators (left ventricular end-systolic volume (LVESV), left ventricular ejection fraction (LVEF), and left ventricular end-systolic diameter (LVESD) were measured by nuclear magnetic resonance (MRI). Read More

View Article and Full-Text PDF

Diagnostic and prognostic utility of eIF6 in glioblastoma: a study based on TCGA and CGGA databases.

Am J Transl Res 2022 15;14(7):5040-5049. Epub 2022 Jul 15.

Department of Neurosurgery, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology) Shenzhen 518020, Guangdong, China.

Background: Among various glioma types, glioblastoma multiforme (GBM) is one of those with the highest malignancy. Although overexpression of eukaryotic translation initiation factor 6 (eIF6), a factor that regulates protein translation initiation, is believed to promote tumor development, its function and potential molecular mechanisms in glioma progression remain uncharacterized. Consequently, we evaluated its diagnostic and prognostic utility in GBM patients. Read More

View Article and Full-Text PDF

A case of Multiple Myeloma with lung plasmacytoma.

Respir Med Case Rep 2022 31;39:101713. Epub 2022 Jul 31.

Department of Respiratory Medicine, Arrazi Hospital, Mohammed VI University Hospital Center, LRMS Laboratory, Faculty of Medicine and Pharmacy, Cadi Ayyad University, Marrakech, Morocco.

Multiple Myeloma (MM) is a malignant proliferation of the plasma cells mainly affecting bone marrow. Most common sites of extramedullary dissemination reported in the literature are skin, liver, kidneys and central nervous system. Multiple Myeloma is rarely associated with lung plasmacytoma. Read More

View Article and Full-Text PDF

Temperature thresholds and screening of febrile people by non-contact measurement of the face using infrared thermography - A methodology proposal.

Sens Biosensing Res 2022 Aug 6;37:100513. Epub 2022 Aug 6.

Post Graduate Program in Sustainable Technologies, Campus Vitória, Federal Institute of Espírito Santo, 1729 Vitória Ave., Vitória 29040-780, ES, Brazil.

Recent outbreaks of infectious diseases such as Covid-19 that have fever as one of the symptoms drive the search for systems to track people with fever quickly and non-contact, also known as sanitary barriers. The use of non-contact infrared-based instruments, especially the infrared thermal imager, has widely spread. However, the screening process has presented low performance. Read More

View Article and Full-Text PDF

Timely initiation of breastfeeding and its associated factors among Turkish mothers: a mixed model research.

Sudan J Paediatr 2022 ;22(1):61-69

Susurluk State Hospital, Department of Pediatrics, Balıkesir, Turkey.

Exploring the determinants of timely initiation of breastfeeding is necessary for planning efficient breastfeeding promotion programmes. The present study aimed to investigate the frequency and related factors of timely initiation of breastfeeding among Turkish mothers. This study was a cross-sectional, descriptive, mixed model study, which was carried out on mothers with healthy children up to 3 years old who presented to the paediatric clinic between 01 November 2019 and 30 December 2019 in a university hospital. Read More

View Article and Full-Text PDF
January 2022

Paediatric gastroenteritis disease characteristics, management and seasonal variation in one region of Ireland: prospective study.

Zakaria Barsoum

Sudan J Paediatr 2022 ;22(1):77-82

Consultant Paediatrician, South West Acute Hospital, United Kingdom.

Background: Acute gastroenteritis (GE) is a clinical syndrome and harbours a significant global burden. Nosocomial acquisition of gastroenteritis results in a significant economic burden. We aim to determine gastroenteritis frequency, disease severity, nosocomial acquisition and clinical spectrum in our region for 2016-2017. Read More

View Article and Full-Text PDF
January 2022

External ventricular drainage: indications and outcome among Sudanese Children.

Sudan J Paediatr 2022 ;22(1):36-46

Department of Neurosurgery, Mawada Hospital, Khartoum, Sudan.

This study reflects our experience in managing Sudanese children with different cranial conditions through external ventricular drainage (EVD): indications for EVD, pathologies faced, and early outcome. A prospective review of cases operated at the National Center for Neurological Sciences was carried out during the period from February 2014 to February 2016. The patients were closely followed up till EVD removal and discharge. Read More

View Article and Full-Text PDF
January 2022

Heterotopic squamous epithelial inclusion cyst in a cervical lymph node in a child: a case report and literature review.

Transl Pediatr 2022 Jul;11(7):1274-1280

Department of Pediatric Surgery, Tianjin Medical University General Hospital, Tianjin, China.

Background: A squamous epithelial inclusion cyst in a lymph node is a rare heterotopic phenomenon. Heterotopic squamous inclusion cysts in cervical lymph nodes are even rarer, and to date, only 3 such cases have been reported in the literature, none of which have described the ultrasound features. Here, we report a pediatric case, focusing on the ultrasonographic manifestations of the disease and the differential diagnosis of cervical space-occupying lesions in children. Read More

View Article and Full-Text PDF

Successful sequential tyrosine kinase inhibitors to overcome a rare compound of EGFR exon 18-18 and EGFR amplification: A case report.

Front Oncol 2022 25;12:918855. Epub 2022 Jul 25.

Thoracic and Medical Oncology Department, Avicenne Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Bobigny, France.

Background: New mutational detection techniques like next-generation sequencing have resulted in an increased number of cases with uncommon mutation and compound mutations [3%-14% of all epidermal growth factor receptor (EGFR) mutations]. In rare exon 18 mutations (3%-6%), G719X and E709X represent the majority, but CMut associating these exon 18 points mutations are even rarer, making the understanding of the impact of epidermal growth factor receptor tyrosine kinase inhibitors still limited. Three generations of EGFR tyrosine kinase inhibitors (TKIs) are available to target EGFR mutations, but according to the types of mutations, the sensitivity to TKI is different. Read More

View Article and Full-Text PDF

Hypertrophic lichen planus on lip mimicking SCC.

Clin Case Rep 2022 Aug 8;10(8):e6191. Epub 2022 Aug 8.

Skin Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.

The lichen planus (LP) is an inflammatory and immune-mediated disorder that can affect the hair, mucous membranes, nails, and skin. Lichen planus rarely affects the lips. In cases of lip involvement, it presents as radiated streaks, lace-like papules, and erosions. Read More

View Article and Full-Text PDF