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Jurors' Gender and Their Fear of False Child Sexual Abuse Accusations Are Related to Their Belief in Child Victims' Allegations.

J Child Sex Abus 2021 Jun 15:1-19. Epub 2021 Jun 15.

The University of Illinois College of Medicine at Chicago, Chicago, IL, USA.

We developed the first Fear of False Accusations scale, measuring the public's fear of personally being the target of untrue child sexual abuse allegations despite no actual wrongdoing as well as the fear of false allegations being a common problem in society. The scale was statistically reliable within a diverse sample of 964 participants. Several months later, in an ostensibly unrelated mock trial experiment, a subset of the participants assumed the role of mock juror and considered a criminal case involving an accusation of child sexual abuse. Read More

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Comparison of injectable filler locations in men and women: An age-matched case analysis.

J Cosmet Dermatol 2021 Jun 15. Epub 2021 Jun 15.

Laser & Skin Surgery Center of New York, New York, NY, USA.

In recent years, the popularity of fillers has risen significantly. Traditionally, women have undergone the vast majority of cosmetic procedures, but men have steadily shown increasing interest. Recently, significant research has been dedicated to understanding the anatomic differences between male and female facial structures and their clinical aesthetic implications, especially for filler placement. Read More

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Clarithromycin As an Alternative and Prophylactic Agent in a Hematopoietic Stem Cell Transplantation Patient.

Am J Case Rep 2021 Jun 15;22:e931731. Epub 2021 Jun 15.

Medical Mycology Research Center, Chiba University, Chiba, Japan.

BACKGROUND Nocardia infections have rarely been reported in hematopoietic stem cell transplantation (HSCT) patients, who usually receive the prophylactic use of sulfamethoxazole/trimethoprim (ST) against Pneumocystis jiroveci. However, the ST prophylaxis, sensitive to Nocardia species, sometimes induces renal toxicities. Therefore, alternative prophylactic or therapeutic drugs are required for nocardiosis in HSCT patients. Read More

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Macrodystrophia Lipomatosa of the Foot: A Case Report of MRI and Histologic Findings Including Pacinian Corpuscle Abnormalities.

JBJS Case Connect 2021 06 15;11(2). Epub 2021 Jun 15.

Departments of Orthopaedic Surgery and Radiology, New York Presbyterian Lower Manhattan Hospital, New York, New York.

Case: A 37-year-old man presented with pain and macrodactyly of a toe. Imaging and histology demonstrated findings consistent with macrodystrophia lipomatosa (MDL). We compared our findings with control tissue obtained from an identical site of a fresh-frozen cadaveric foot from the same anatomical site. Read More

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Internal Magnetic Lengthening and Reconstruction with Free TRAM Flap After Traumatic Transfemoral Amputation: A Case Report.

JBJS Case Connect 2021 06 15;11(2). Epub 2021 Jun 15.

Division of Plastic Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota.

Case: This is a case of a 41-year-old man who sustained a traumatic proximal transfemoral amputation with loss of adductor function and inadequate soft tissue. Wound closure was achieved with split-thickness skin grafting. Subsequently, femoral lengthening was achieved with an internal magnetic lengthening nail. Read More

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Medial Clavicle Fracture Fixation Including the Sternum: A Case Report.

JBJS Case Connect 2021 06 15;11(2). Epub 2021 Jun 15.

Department of Orthopedic Surgery, John Peter Smith Hospital, Fort Worth, Texas.

Case: A 29-year-old man presented with a displaced medial clavicle fracture. Surgical repair was performed using a precontoured plate designed for the contralateral distal clavicle, and medial fixation was accomplished at the sternum. The patient had no complications and demonstrated full strength and range of motion at the 8-month follow-up. Read More

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Transoral Gunshot Injury Resulting in Mechanical Block to Cervical Rotation: A Case Report.

JBJS Case Connect 2021 06 15;11(2). Epub 2021 Jun 15.

Cardiff and Vale Orthopaedic Center, University Hospital Llandough, Penarth, United Kingdom.

Case: We report a case of self-inflicted transoral gunshot injury in a 24-year-old man resulting in mechanical block to cervical rotation. Anterior surgical removal of the pellet was successful with the patient experiencing no early or long-term functional deficits.

Conclusion: Given the rarity of a cervical spine injury from gunshot wound without long-term complications, this unique case supports the role of early operative management in such injuries. Read More

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Morbidity and Mortality Trends of Pancreatitis: An Observational Study.

Surg Infect (Larchmt) 2021 Jun 15. Epub 2021 Jun 15.

Department of Medicine, Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, University of Minnesota, Minneapolis, Minnesota, USA.

Pancreatitis accounts for more than $2.5 billion of healthcare costs and remains the most common gastrointestinal (GI) admission. Few contemporary studies have assessed temporal trends of incidence, complications, management, and outcomes for acute pancreatitis in hospitalized patients at the national level. Read More

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Comparison of Joint and Landmark Modeling for Predicting Cancer Progression in Men With Castration-Resistant Prostate Cancer: A Secondary Post Hoc Analysis of the PREVAIL Randomized Clinical Trial.

JAMA Netw Open 2021 Jun 1;4(6):e2112426. Epub 2021 Jun 1.

Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.

Importance: Dynamic prediction models may help predict radiographic disease progression in advanced prostate cancer.

Objective: To assess whether dynamic prediction models aid prognosis of radiographic progression risk, using ongoing longitudinal prostate-specific antigen (PSA) assessments.

Design, Setting, And Participants: This prognostic study used data from the PREVAIL study to compare dynamic models for predicting disease progression. Read More

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Sphenoid sinus pseudoaneurysm with carotid cavernous fistula presenting with delayed subarachnoid hemorrhage: A case report.

Medicine (Baltimore) 2021 Jun;100(24):e26383

Department of Radiology.

Rationale: Sphenoid sinus pseudoaneurysm arising from the cavernous segment of the internal carotid artery (ICA) caused by traumatic vessel injury is rare, and rarer is a concomitant carotid-cavernous fistula (CCF). In particular, delayed subarachnoid hemorrhage (SAH) due to pseudoaneurysm rupture has not been reported to-date in literature. Here, we report a case of sphenoid sinus pseudoaneurysm with CCF presenting with delayed SAH. Read More

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Clinicopathological analysis and genomic profiling of a rare histiocyte-rich rhabdomyoblastic tumor: A case report.

Medicine (Baltimore) 2021 Jun;100(24):e26105

Department of General Surgery, Shenzhen University General Hospital & Carson International Cancer Research Centre, Shenzhen, P.R. China.

Rationale: Skeletal muscle tumors are traditionally classified as rhabdomyomas or rhabdomyosarcomas. However, some soft tissue tumors cannot easily be identified as benign or malignant. We report a case of a histiocyte-rich rhabdomyoblastic tumor, with pathologic characteristics distinct from either rhabdomyoma or rhabdomyosarcoma. Read More

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Targeting androgen receptor signaling: a historical perspective.

Endocr Relat Cancer 2021 Jun 1. Epub 2021 Jun 1.

A Zoubeidi, Urologic Sciences, University of British Columbia, Vancouver, V6H 3Z6, Canada.

The first case of prostate cancer was identified by histological examination by J. Adams, a surgeon at The London Hospital, in 1853. In his report, Adams noted that the condition was "a very rare disease". Read More

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An autopsy case of corticobasal syndrome with pure diffuse Lewy Body Disease.

Neurocase 2021 Jun 15:1-7. Epub 2021 Jun 15.

Department of Neurology, Tokyo Metropolitan Bokutoh Hospital, Tokyo, Japan.

Corticobasal syndrome (CBS) is associated with diverse pathological substrates such as tau, prion protein, transactive response and, rarely, alpha synuclein. We report the case of a54-year-old man, who presented with asymmetric levodopa-poor-responsive parkinsonism, frontal lobe signs and behavioral changes. He was diagnosed with CBS, and postmortem analyses revealed Lewy body disease Braak stage VI without comorbid pathologies. Read More

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Pop-out illusion as the initial presentation of posterior cortical atrophy.

Neurocase 2021 Jun 15:1-4. Epub 2021 Jun 15.

Department of Neurological Sciences, Christian Medical College, Vellore, India.

Posterior cortical atrophy is a rare neurodegenerative disease that presents with progressive higher-order visual impairment. We describe a case of posterior cortical atrophy in a 62-year-old, right-handed man, who initially presented with difficulty in viewing the television screen, followed by reading difficulty a few months later, and then developed features of Balint's syndrome over the course of 3 years. We report an illusion, which we noticed at the time of the initial presentation, where the characters in the television appeared to be popping out of the screen. Read More

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Use of Shockwave intravascular lithotripsy for the treatment of symptomatic and severely calcified superior mesenteric artery stenosis.

CVIR Endovasc 2021 Jun 14;4(1):53. Epub 2021 Jun 14.

Division of Vascular and Interventional Radiology, Department of Radiology, Hospital Clínico Universitario de Santiago de Compostela, A Coruña, Spain.

Background: We present the use of intravascular lithotripsy as a treatment for highly calcified superior mesenteric artery stenosis.

Case Presentation: A 67-year-old diabetic man had chronic postprandial abdominal pain and weight loss. Computed tomography angiography revealed highly calcified stenosis of the superior mesenteric artery. Read More

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Performance of African-ancestry-specific polygenic hazard score varies according to local ancestry in 8q24.

Prostate Cancer Prostatic Dis 2021 Jun 14. Epub 2021 Jun 14.

School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA, USA.

Background: We previously developed an African-ancestry-specific polygenic hazard score (PHS46+African) that substantially improved prostate cancer risk stratification in men with African ancestry. The model consists of 46 SNPs identified in Europeans and 3 SNPs from 8q24 shown to improve model performance in Africans. Herein, we used principal component (PC) analysis to uncover subpopulations of men with African ancestry for whom the utility of PHS46+African may differ. Read More

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Vascular comorbidities worsen prognosis of patients with heart failure hospitalised with COVID-19.

Open Heart 2021 06;8(1)

Cardiovascular Disease, UTHSC College of Medicine Chattanooga, Chattanooga, Tennessee, USA.

Background: Prior diagnosis of heart failure (HF) is associated with increased length of hospital stay (LOS) and mortality from COVID-19. Associations between substance use, venous thromboembolism (VTE) or peripheral arterial disease (PAD) and its effects on LOS or mortality in patients with HF hospitalised with COVID-19 remain unknown.

Objective: This study identified risk factors associated with poor in-hospital outcomes among patients with HF hospitalised with COVID-19. Read More

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Can PIMS-TS lead to a facial nerve palsy?

BMJ Case Rep 2021 Jun 14;14(6). Epub 2021 Jun 14.

Department of Infectious Diseases and Tropical Medicine, Guys and St Thomas Hospital, London, UK.

Paediatric inflammatory multisystem syndrome-temporally associated with SARS-CoV-2 (PIMS-TS) is a recently described syndrome. We describe the case of a 17-year-old man presenting with a recent illness consistent with COVID-19 who presented with fever, chest pain and anterior uveitis. He was treated with aspirin, pulsed methylprednisolone and tocilizumab followed by oral steroids. Read More

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Eptifibatide-induced profound thrombocytopaenia: a rare complication.

BMJ Case Rep 2021 Jun 14;14(6). Epub 2021 Jun 14.

Interventional Cardiology, Cardiology, Carle Foundation Hospital, Urbana, Illinois, USA.

Drug-induced immune thrombocytopaenia (DITP) is a type of thrombocytopaenia caused by medications. It is one of the common causes of unexplained thrombocytopaenia. It is caused by the formation of autoantibodies against a particular drug and is commonly observed with medications like heparin and beta-lactam antibiotics. Read More

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Leg ulceration due to cutaneous melioidosis in a returning traveller.

BMJ Case Rep 2021 Jun 14;14(6). Epub 2021 Jun 14.

Hospital for Tropical Diseases and Department of Dermatology, University College London Hospitals NHS Foundation Trust, London, UK.

A 26-year-old man, returned to the UK having travelled extensively in Asia. He was referred with a 3-month history of distal leg ulceration following an insect bite while in Thailand. Despite multiple courses of oral antibiotics, he developed two adjacent ulcers. Read More

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People with amputations in rural Sierra Leone: the impact of 3D-printed prostheses.

BMJ Case Rep 2021 Jun 14;14(6). Epub 2021 Jun 14.

Masanga Medical Research Unit, Masanga Hospital, Masanga, Sierra Leone.

We report the case of a man with a transhumeral amputation in a rural area of Sierra Leone. The patient had fractured his humerus during a football match. Due to lack of transportation and medical centres nearby, the patient was seen by a traditional healer. Read More

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A Case Report of Torsade de Pointes and Brugada Pattern Associated with Loperamide Misuse and Supratherapeutic Loperamide Concentrations.

J Emerg Med 2021 Jun 11. Epub 2021 Jun 11.

Department of Emergency Medicine, Denver Health and Hospital Authority, Denver, Colorado; Rocky Mountain Poison and Drug Safety, Denver Health and Hospital Authority, Denver, Colorado.

Background: Loperamide, commonly sold under the brand name Imodium® (Johnson & Johnson, Fort Washington, PA), is a widely available, over-the-counter antidiarrheal medication that possesses µ-opioid agonist properties and can have catastrophic cardiac events when misused or abused. Since the start of the opioid epidemic in the United States, there has been an increasing number of case reports and deaths linking loperamide abuse with cardiac events such as torsades de pointes (TdP) and Brugada syndrome.

Case Report: This case report presents a 22-year-old man who presented in cardiac arrest from polymorphic ventricular tachycardia consistent with TdP and a Type 1 Brugada pattern after intentional loperamide abuse. Read More

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The Dilemma, Conversion Disorder or Stiff Person Syndrome, a Case Report.

Sultana Jahan

CNS Spectr 2021 Apr;26(2):145-146

University of Missouri, Department of Psychiatry, Columbia, MO, USA.

Study Objectives: The main objectives of this case study are 1. Clinicians facing symptoms that are difficult to interpret should exercise caution in diagnosing conversion disorder. 2. Read More

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Biportal endoscopic posterior lumbar decompression and vertebroplasty for extremely elderly patients affected by lower lumbar delayed vertebral collapse with lumbosacral radiculopathy.

J Orthop Surg Res 2021 Jun 14;16(1):380. Epub 2021 Jun 14.

Department of Orthopedic Surgery, Spine Center, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, 1, Singil-ro, Yeongdeungpo-gu, Seoul, Republic of Korea, 07441.

Background: Lower lumbar osteoporotic vertebral compression fracture in extremely elderly patients can often lead to lumbosacral radiculopathy (LSR) due to delayed vertebral collapse (DVC). Surgical intervention requires posterior instrumented lumbar fusion as well as vertebral augmentation or anterior column reconstruction depending on the cleft formation and intravertebral instability. However, it is necessary to decide on surgery in consideration of the patient's frail status, surgical invasiveness, and rehabilitation. Read More

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Anti-neutrophil cytoplasmic antibody-associated vasculitis accompanied by type II heparin-induced thrombocytopenia resulting in asymptomatic cerebral infarction: a case report.

BMC Nephrol 2021 Jun 14;22(1):220. Epub 2021 Jun 14.

Department of Hypertension and Nephrology, NTT Medical Centre, 5-9-22, Higasi- Gotanda, Shinagawa-ku, 141-8625, Tokyo, Japan.

Background: Heparin-induced thrombocytopenia (HIT) involves platelet activation and aggregation caused by heparin or HIT antibodies associated with poor survival outcomes. We report a case of HIT that occurred after hemodialysis was started for rapidly progressive glomerulonephritis (RPGN), which was caused by anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV), and ultimately resulted in asymptomatic cerebral infarction.

Case Presentation: A 76-year-old Japanese man was urgently admitted to our hospital for weight loss and acute kidney injury (serum creatinine: 12 mg/dL). Read More

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Antibiotic prescriptions and risk factors for antimicrobial resistance in patients hospitalized with urinary tract infection: a matched case-control study using the French health insurance database (SNDS).

BMC Infect Dis 2021 Jun 14;21(1):571. Epub 2021 Jun 14.

Epidemiology and Modeling of bacterial Evasion to Antibacterials Unit (EMEA), Institut Pasteur, 25-28, Rue du Dr. Roux, 75724, Paris Cedex 15, France.

Background: Antibiotic resistance is increasing among urinary pathogens, resulting in worse clinical and economic outcomes. We analysed factors associated with antibiotic-resistant bacteria (ARB) in patients hospitalized for urinary tract infection, using the comprehensive French national claims database.

Methods: Hospitalized urinary tract infections were identified from 2015 to 2017. Read More

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A genetic interaction of NRXN2 with GABRE, SYT1 and CASK in migraine patients: a case-control study.

J Headache Pain 2021 Jun 14;22(1):57. Epub 2021 Jun 14.

UnIGENe, IBMC - Institute for Molecular and Cell Biology; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.

Background: Migraine is a multifactorial disorder that is more frequent (two to four times) in women than in men. In recent years, our research group has focused on the role of neurotransmitter release and its regulation. Neurexin (NRXN2) is one of the components of the synaptic vesicle machinery, responsible for connecting intracellular fusion proteins and synaptic vesicles. Read More

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[Complete Remission of Metastatic Renal Cell Carcinoma with Invasion of the Duodenum and Pancreas after Treatment with Nivolumab Plus Ipilimumab Followed by Axitinib and Surgery : A Case Report].

Hinyokika Kiyo 2021 May;67(5):197-203

The Department of Urology, Kyoto University Hospital.

A man in his 60s was diagnosed with clear cell carcinoma of the right kidney with multiple lung metastases, tumor thrombus of the inferior vena cava (IVC), and invasion of the duodenum and pancreas. Ipilimumab plus nivolumab was administered as first-line therapy. After 3 treatment courses, computed tomography (CT) demonstrated a slight decrease in the size of the primary tumor and lung metastases. Read More

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[A Case of Rapidly Growing Sarcomatoid Urothelial Carcinoma of the Renal Pelvis and Ureter].

Hinyokika Kiyo 2021 May;67(5):191-195

The Department of Diagnostic Pathology, Tenri Hospital.

75 year-old man followed up regularly for the treatment of lung cancer came to our hospital with a chief complaint of general malaise. Blood test results showed deterioration in the renal function, and computed tomography (CT) confirmed left hydronephrosis. He was admitted to the hospital with the diagnosis of obstructive pyelonephritis. Read More

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[Renal Artery Stenting for Spontaneous Renal Artery Dissection with Renal Infarction].

Hinyokika Kiyo 2021 May;67(5):187-190

The Department of Urology, Kawasaki Saiwai Hospital.

Spontaneous renal artery dissection (SRAD) is extremely rare and the management procedures have not been established. We report a case of endovascular stent placement for SRAD with renal infarction. A 53-year-old man visited a hospital with the complaint of lumbago. Read More

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