2,181,086 results match your criteria case histories

Emphysema of the periorbital region and mediastinum in a young child following a dental procedure.

J AAPOS 2021 May 12. Epub 2021 May 12.

Universitair Ziekenhuis Brussel, Vrij Universiteit Brussel, Brussels, Belgium.

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Bilateral quadratus lumborum block for management of persistent post-operative paralytic ileus: a case report.

Braz J Anesthesiol 2021 May 12. Epub 2021 May 12.

Centro Hospitalar Tondela Viseu, EPE, Viseu, Portugal.

We report the case of a 62-year-old female who suffered from a persistent postoperative paralytic ileus following an urgent open cholecystectomy. On the fifth postoperative day we performed a bilateral Quadratus Lumborum Block (QLB) type 1 block which resulted in a progressive resolution of the condition. This case report highlights that QLB is not only limited to somatic pain control, but it can also be used to alleviate visceral pain, namely in the context of paralytic ileus management in the postoperative period. Read More

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Future Orientation as a Cross-Cutting Protective Factor Against Multiple Forms of Violence.

J Pediatr 2021 May 12. Epub 2021 May 12.

University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Division of Adolescent and Young Adult Medicine, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.

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Consideration triggered by the choice of heterophilic antibody interference detection tests in measuring ACTH for a teenager boy with a rare adrenal disease.

Clin Chim Acta 2021 May 12. Epub 2021 May 12.

Department of Clinical Laboratory, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Science, Beijing 100730, P.R. China. Electronic address:

Background: Plasma ACTH is an important marker for Cushing syndrome; inaccurate measurement of ACTH concentrations due to the serum heterophile antibody may mislead diagnosis by physicians. We describe the case of a teenage boy with a rare adrenal disease who presented falsely increased ACTH concentrations (20.3 pg/ml; Siemens Immulite). Read More

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Prenatal sonographic diagnosis of X-linked hypohidrotic ectodermal dysplasia: An unusual case.

J Clin Ultrasound 2021 May 15. Epub 2021 May 15.

Department of Gynecology, Gansu Provincial Maternity and Child-Care Hospital, Lanzhou, Gansu Province, China.

X-linked hypohidrotic ectodermal dysplasia (XLHED) is a rare congenital genetic disorder caused by mutations in the ectodysplasin A gene, resulting in dysplasia or complete absence of teeth, hair, and sweat glands. XLHED is rarely diagnosed prenatally. We describe a case of XLHED diagnosed with prenatal sonography and umbilical cord blood gene testing. Read More

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Diabetes coexistent with Charcot-Marie-Tooth disease presenting as a recurrent foot ulcer misdiagnosed as diabetic foot: a case report.

J Diabetes Investig 2021 May 15. Epub 2021 May 15.

Innovation Center for Wound Repair, Diabetic Foot Care Center, Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, P. R. China.

Both diabetes mellitus (DM) and Charcot-Marie-Tooth disease (CMT) can lead to severe peripheral neuropathy. The differential diagnosis of peripheral neuropathy is difficult due to the similar clinical features. There are still some clues, such as unusual muscle atrophy, unmatched severity of peripheral neurogenic damage with nephropathy or retinopathy, which could alert clinicians to make differential diagnosis. Read More

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Response to crizotinib in a patient with MET-amplified hepatocellular carcinoma.

Hepatol Res 2021 May 15. Epub 2021 May 15.

Department of Hepatobiliary Surgery, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.

Aims: Molecular profiling of hepatocellular carcinoma (HCC) has helped identify actionable genomic alterations that may guide therapeutic decision-making and clinical trial enrollment. However, in clinical practice, next-generation sequencing (NGS) is not extensively used in routine clinical care to identify patients with HCC who are likely to benefit from genome-directed targeted therapies.

Methods: Here, we describe the case of a 66-year-old man with advanced HCC. Read More

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Aeration in sludge holding tanks as an economical means for biosolids odor control - A case study.

Water Environ Res 2021 May 15. Epub 2021 May 15.

Department of Civil and Environmental Engineering, Center for Applied Water Research and Innovation, 44961 Loudoun Water Way, Ashburn, VA, 20147, USA.

Abnormally high odor detection threshold (DT) values were detected for biosolids produced at one of the Water Resource Recovery Facilities (WRRFs) of Washington Suburban Sanitary Commission. As an inexpensive countermeasure, aeration of thickened sludge holding tanks (SHTs) was tested as a solution for mitigating the subsequent biosolids odor emission. Experimental results indicated that the extremely low oxidation reduction potential (ORP) in the SHTs and the fermentation of high-rate activated sludge were primarily contributors to the odor emission from the dewatered cake. Read More

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Successful treatment for the different and rare cause of facial lymphedema: Morbus Morbihan disease.

Int J Dermatol 2021 May 15. Epub 2021 May 15.

Department of Physical Medicine and Rehabilitation, Gulhane Education and Research Hospital, Ankara, Turkey.

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Lymphatico-venous anastomosis in chronic ulcer with venous insufficiency: A case report.

Microsurgery 2021 May 15. Epub 2021 May 15.

Plastic Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.

Patients presenting with chronic wounds in venous insufficiency often represent a challenge, like other conditions, like lymphatic impairment, may complicate the wound healing process. The purpose of this report is to highlight how the treatment of lymphatic impairment may be beneficial in patients affected by chronic ulcers with concomitant venous insufficiency. We present the case of a 78-year-old woman affected by chronic venous insufficiency (CVI) with long-lasting ulcers secondary to sclerosing agents treatment for varicose veins. Read More

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Tracheal polypoid combined small cell lung cancer (C-SCLC): A case report.

Thorac Cancer 2021 May 14. Epub 2021 May 14.

Division of Thoracic Surgery, IRCCS Humanitas Research Hospital, Milan, Italy.

Small cell lung cancer (SCLC) is an aggressive malignancy with a poor prognosis that accounts for 10% of all cases of clinical lung cancer. Due to its high growth fraction and rapid doubling time it is usually diagnosed as extensive local or metastatic disease in 60%-70% of cases. Combined small cell lung cancer (C-SCLC) is a relatively rare subtype of SCLC and is defined as SCLC combined with any elements of non-small cell lung cancer (NSCLC). Read More

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Swyer Syndrome: A case of dysgerminoma solely within the fallopian tube.

J Pediatr Adolesc Gynecol 2021 May 11. Epub 2021 May 11.

Gynaecology Department, Manchester University NHS Foundation Trust, Saint Mary's Hospital, Oxford Road, Manchester, M13 9WL, United Kingdom.

Background: 46XY pure gonadal dysgenesis (Swyer syndrome) is a rare disorder of sexual development. Patients have a 46XY karyotype, though phenotypically appear female with normal external genitalia and vagina. While patients exhibit normal Mullerian structures (uterus, fallopian tubes and vagina); they possess a pair of bilateral undifferentiated gonad streaks. Read More

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Valve-in-valve Prosthesis - Late Morphological Findings.

Cardiovasc Pathol 2021 May 11:107345. Epub 2021 May 11.

University of Toronto, Departments of Laboratory Medicine & Pathobiology & Departments of Pathology & Cardiovascular Surgery, Toronto General Hospital, University Health Network, Toronto, Canada.

Since its implantation in 2002, transcatheter aortic valve implantation (TAVI) has become the preferred intervention for patients with severe aortic stenosis and significant co-morbidities. In 2007, it was adopted as a rescue procedure for failed bioprosthetic valves, now known as the valve-in-valve (VIV) procedure. Unlike other modes of treatment with a multitude of phase 4 post-marketing surveillance (PMS) data, use of these valves have increased rapidly even without long term durability data on this procedure and the near lack of information on the pathology of failed transcatheter aortic valve replacement (TAVR) bioprosthesis and especially after the VIV procedure. Read More

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Pediatric intraoperative ciliary block.

J AAPOS 2021 May 11. Epub 2021 May 11.

Bascom Palmer Eye Institute, University of Miami Health System, Miami, Florida.

Pediatric patients who undergo intraocular surgery are at risk for many of the same perioperative complications as adults. The same methodical approach to assessing perioperative shallowing of the anterior chamber that presents in the adult population should be followed for children. We present a rare case of intraoperative ciliary block in a 3-year-old boy undergoing a second glaucoma drainage device implantation that was successfully treated with pars plana vitrectomy and hyaloid-zonulo-iridectomy. Read More

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Optical changes and apparent emmetropization in a patient with a peripheral unilateral lens coloboma.

J AAPOS 2021 May 11. Epub 2021 May 11.

Department of Ophthalmology, Shaare Zedek Medical Center, Jerusalem, Israel, affiliated to the Hebrew University, Jerusalem, Israel.

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Early detection of P.1 variant of SARS-CoV-2 in a cluster of cases in Salvador, Brazil.

Int J Infect Dis 2021 May 11. Epub 2021 May 11.

Instituto Gonçalo Moniz, Fiocruz, Salvador, Brazil.

We report three cases of severe COVID-19 due to the SARS-CoV-2 P.1 lineage in a familial cluster detected in Salvador, Bahia-Brazil. All cases were linked to travel by family members from the state of Amazonas to Bahia in late December 2020. Read More

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Anthrax meningoencephalitis complicated with brain abscess - A case report.

Int J Infect Dis 2021 May 11. Epub 2021 May 11.

Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; Dr Victor Babes Clinical Hospital of Infectious and Tropical Diseases, Bucharest, Romania.

Bacillus anthracis is a sporulating Gram positive rod whose main route of entry being cutaneous. Anthrax meningitis is usually fulminant and fatal. We present here a case of anthrax meningoencephalitis complicated with brain abscess successfully treated. Read More

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Non-Healing Leg Ulcers in a Patient with Rheumatoid Arthritis.

Am J Med 2021 May 11. Epub 2021 May 11.

Division of Rheumatology, University of Texas Medical Branch, Galveston, Texas.

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Clinical Communication to the Editor: Pancytopenia in a Cameroonian patient with AIDS.

Am J Med 2021 May 11. Epub 2021 May 11.

Department of Internal Medicine, University of Maryland Medical Center, 22 South Greene Street, Baltimore, MD 21201; Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201.

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Parathyroid hormone-related peptide (PTHrp)-secreting liver metastatic large-cell neuroendocrine carcinoma of the sigmoid colon.

Am J Med 2021 May 11. Epub 2021 May 11.

Insitute of Pathology Saarbrücken-Rastpfuhl, Saarbrücken, Germany. Electronic address:

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False positive syphilis serologies in a woman receiving intravenous immunoglobulin.

Am J Med 2021 May 11. Epub 2021 May 11.

Department of Pediatrics, Montreal Children`s Hospital of the McGill University Health Centre, Montreal, Quebec, Canada. Electronic address:

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Novel oral anticoagulants in the treatment of radial artery occlusion.

Catheter Cardiovasc Interv 2021 May 14. Epub 2021 May 14.

Division of Cardiology, McGuire Veterans Affairs Medical Center, Richmond, Virginia, USA.

Transradial access of the vascular system for coronary angiography and percutaneous coronary intervention has become the primary approach in several cardiac catheterization laboratories across the world. The paradigm shift from transfemoral access has been driven by improved outcomes in patients undergoing these cardiac procedures by transradial access. Radial artery occlusion is the most common vascular complication of transradial coronary procedures. Read More

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Social communication disorder and behavioural addiction: Case report and clinical implications.

J Behav Addict 2021 May 13. Epub 2021 May 13.

1Psychiatry and Mental Health Department, CHU de Nantes, Nantes, France.

Background: Social communication disorder (SCD) is a neurodevelopmental disorder that includes communication difficulties. Literature linking SCD and addictions is scarce, and there are only a few case reports regarding the co-occurrence of addiction and autism disorder spectrum, and only one of them addressed behavioural addictions.

Case Presentation: We report MC's case, who displayed an SCD and sexual addiction (SA). Read More

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A family with partially penetrant multicentric carpotarsal osteolysis due to gonadal mosaicism: First reported case.

Am J Med Genet A 2021 May 14. Epub 2021 May 14.

Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.

Multicentric carpotarsal osteolysis (MCTO) is an autosomal dominant condition characterized by carpal-tarsal abnormalities; over half of affected individuals also develop renal disease. MCTO is caused by mutations of MAFB; however, there is no clear phenotype-genotype correlation. We describe the first reported family of variable MCTO phenotype due to mosaicism: the proband had classical skeletal features and renal involvement due to focal segmental glomerulosclerosis (FSGS), and the father had profound renal impairment due to FSGS, necessitating kidney transplantation. Read More

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Symptomatic mosaicism for a novel FBN1 splice site variant in a parent causing inherited neonatal Marfan syndrome.

Am J Med Genet A 2021 May 14. Epub 2021 May 14.

Division of Medical Genetics, Department of Pediatrics, London Health Sciences Centre, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.

Neonatal Marfan syndrome is a severe, early onset presentation of pathogenic variants in FBN1. Because of the significant cardiac involvement and early mortality, nearly all reported cases have been de novo, and the disorder has not been documented to be inherited from a symptomatic parent. Here, we present a female infant with neonatal Marfan syndrome who was born to a father with Marfan syndrome. Read More

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Skeletal and molecular findings in 51 Cleidocranial dysplasia patients from Turkey.

Am J Med Genet A 2021 May 13. Epub 2021 May 13.

Department of Medical Genetics, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey.

Loss or decrease of function in runt-related transcription factor 2 encoded by RUNX2 is known to cause a rare autosomal-dominant skeletal disorder, cleidocranial dysplasia (CCD). Clinical spectrum and genetic findings in 51 CCD patients from 30 unrelated families are herein presented. In a majority of the patients, facial abnormalities, such as delayed fontanel closure (89%), parietal and frontal bossing (80%), metopic groove (77%), midface hypoplasia (94%), and abnormal mobility of shoulders (90%), were recorded following clinical examination. Read More

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Proximal Weakness Involvement In The First Italian Case Of Charcot-Marie-Tooth 2cc Harboring A Novel Frameshift Variant In Nefh.

J Peripher Nerv Syst 2021 May 13. Epub 2021 May 13.

Department of Neuroscience, Reproductive and Odontostomatological Science, University of Naples "Federico II", Naples, Italy.

Charcot-Marie-Tooth (CMT) diseases are a clinically and genetically heterogeneous group of disorders. Different variants in the neurofilament heavy chain (NEFH) gene have been described to cause the CMT2CC subtype. Here we report the first Italian patient affected by CMT2CC, harboring a novel variant in NEFH. Read More

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Ultrasonic vibration and thermo-hydrodynamic technique for filling root canals: technical overview and a case series.

Y S Cho

Int Endod J 2021 May 13. Epub 2021 May 13.

Department of Conservative Dentistry, College of Dentistry, Yonsei University, and Private Practice, Goyang-si, Korea.

Aim: To present a novel root canal filling technique: Ultrasonic Vibration & Thermo-Hydrodynamic Obturation (VibraTHO), and its rationale with a series of cases.

Summary: The VibraTHO technique was used to fill the root canals of three clinically challenging cases: A C-shaped mandibular molar with complex anatomy, an infected C-shaped mandibular molar with a periapical lesion that required retreatment, and apically bifurcating mesiobuccal canals with a common orifice in a maxillary second molar. The cases were followed-up for 15, 7, and 37 months, respectively. Read More

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Inclusion of Cephalexin in COVID-19 Treatment Combinations May Prevent Lung Involvement in Mild Infections: A Case Report with Pharmacological Genomics Perspective.

Glob Med Genet 2021 Jun 22;8(2):78-81. Epub 2021 Mar 22.

Department of Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.

Novel coronavirus disease 2019 (COVID-19) is caused by a nonsegmented positive sense RNA, enveloped RNA virus that belongs to the family of β-coronaviridae. This virus shall cause acute respiratory distress syndrome (ARDS) which consequently leads to breathing difficulty and need to admit to intensive care units (ICUs). The current conventional treatment combination in most of the hospitals in Iran includes azithromycin 500 + naproxen 500 + vitamin C 1,000 + Zinc + vitamin D3 1,000. Read More

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