1,617 results match your criteria case fibrosing

Cryptogenic Fibrosing Pleuritis.

Eur J Case Rep Intern Med 2021 17;8(5):002498. Epub 2021 May 17.

Department of Medicine and Surgery, Respiratory Disease and Lung Function Unit, University of Parma, Parma, Italy.

We report the case of a 46-year-old male patient who was referred for chest pain and bilateral pleural effusion. Despite treatment with antibiotics and steroids, the pleural effusion worsened over a few months until pulmonary function was halved. The CT scan showed bilateral pleural thickening with right basal opacity. Read More

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Nonspecific orbital inflammation and thyroid eye disease, a rare comorbidity: report of two cases and review of literature.

BMC Ophthalmol 2021 Jun 5;21(1):251. Epub 2021 Jun 5.

Isfahan Eye Research Center, Department of Ophthalmology, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: To present the very rare comorbidity of developing non-specific orbital inflammation (NSOI) in two patients with histories of definite thyroid eye disease (TED).

Case Presentation: Both patients complained of new-onset progressive proptosis although their thyroid disease was controlled and computed tomography scan revealed an intraorbital inflammatory mass. The pathological assessment indicated that both patients had developed fibrosing NSOI. Read More

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Frontal Fibrosing Alopecia: Is There a Link in Relatives?

Skin Appendage Disord 2021 Apr 4;7(3):206-211. Epub 2021 Mar 4.

Universidad Autónoma de Nuevo León, Hospital Universitario "Dr. José Eleuterio González", Dermatology Department, Monterrey, Mexico.

Frontal fibrosing alopecia (FFA) is an acquired primary lymphocytic cicatricial alopecia characterized by frontotemporal hairline recession, leading to scarring alopecia with a band-like distribution. Prevalence is increasing worldwide, being the most frequent cause of primary scarring alopecia. The natural history of this condition is variable; however, slow progression with spontaneous remission is the most frequent reported outcome. Read More

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Vascular homografts as bypass grafts for superior vena cava syndrome due to idiopathic fibrosing mediastinitis.

J Vasc Surg Cases Innov Tech 2021 Jun 22;7(2):335-338. Epub 2021 Apr 22.

Department of Cardiovascular Surgery, Iaso Children's Hospital, Athens, Greece.

Fibrosing mediastinitis can lead to superior vena cava obstruction by generating a fibroinflammatory mass in the mediastinum. Surgical caval reconstruction with conduits could be indicated for cases of unsuccessful or technically unfeasible endovascular stenting and angioplasty. The use of cryopreserved vascular homografts seems to be better than prosthetic conduits for mid- and long-term patency, as was observed in the case we have described in the present report. Read More

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Clinical Features of Fibrosing Mediastinitis in Japanese Patients: Two Case Reports and a Literature Review.

Intern Med 2021 May 22. Epub 2021 May 22.

Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Japan.

Fibrosing mediastinitis (FM) is a rare fibroinflammatory disease of the mediastinum with an etiology and clinical features that vary by world region. The characteristics of FM in Japan are still unknown. We herein report two Japanese patients with FM who were treated with corticosteroids and responded well. Read More

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Immunoglobulin G4-Related Disease Accompanied by Primary Myelofibrosis: Case Report.

Front Med (Lausanne) 2021 4;8:638794. Epub 2021 May 4.

Department of Rheumatology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Science, Beijing, China.

Immunoglobulin G4-related disease (IgG4-RD) is a heterogeneous autoimmune fibrosing disorder that presents common pathologic features but with unclear etiology. We report a rare case of IgG4-RD accompanied by primary myelofibrosis that eventually transformed into acute myeloid leukemia. A 50-year-old woman suffered from progressive lacrimal and parotid gland enlargement, diaphoresis, and rapid weight loss. Read More

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Refractory pleural effusion as a rare complication of pulmonary vascular stenosis induced by fibrosing mediastinitis: a case report and literature review.

J Int Med Res 2021 May;49(5):3000605211010073

Department of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.

Fibrosing mediastinitis (FM) is a progressive, life-threatening disease characterized by extrinsic compression of mediastinal bronchovascular structures, and the clinical manifestations largely depend upon the affected structures. Pleural effusion is rarely reported in patients with FM. We herein describe a 70-year-old man who presented with recurrent breathlessness and refractory left pleural effusion. Read More

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[Immunoglobulin G4( IgG4)-related Fibrosing Mediastinitis Localized in the Retrosternal Area:Report of a Case].

Kyobu Geka 2021 Apr;74(4):317-320

Department of Thoracic Surgery, Kanazawa Medical Center, Kanazawa, Japan.

An 84-year-old man was referred to our out-patient clinic with an elongated mass localized to the retrosternal area that was incidentally identified by computed tomography. On 18F-fluorodeoxyglucose-positron emission tomography, this lesion showed intense tracer uptake. Thus, a surgical biopsy under thoracoscopy was performed. Read More

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Eyebrow Regrowth in Patients with Frontal Fibrosing Alopecia Treated with Low-Dose Oral Minoxidil.

Skin Appendage Disord 2021 Feb 2;7(2):112-114. Epub 2020 Dec 2.

Trichology Unit, Hospital Regional da Asa Norte (HRAN), Brasília-DF, Brasília, Brazil.

Introduction: The eyebrows are an important facial feature that shape one's physical appearance and play a role in non-verbal communication. Partial or complete eyebrow loss is seen in most patients with frontal fibrosing alopecia (FFA). Despite the scarring nature of FFA, eyebrow hair regrowth has been previously reported. Read More

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February 2021

Three cases of sequential treatment with nintedanib following pulsed-dose corticosteroids for acute exacerbation of interstitial lung diseases.

Respir Med Case Rep 2021 9;33:101385. Epub 2021 Mar 9.

Department of Respiratory Medicine, Hamanomachi Hospital, Fukuoka, 810-8539, Japan.

We describe three cases of acute exacerbation of interstitial lung diseases (ILDs) in which patients were treated with pulsed-doses of corticosteroids followed by nintedanib and maintenance doses of corticosteroids. All cases responded well to pulsed-dose corticosteroids. However, in conventional practice, corticosteroids can complicate adverse events, including opportunistic infections, diabetes, and osteoporosis. Read More

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Alopecia Areata Mimicking Frontal Fibrosing Alopecia.

Cureus 2021 Feb 15;13(2):e13361. Epub 2021 Feb 15.

Dermatology, Sinclair Dermatology, Melbourne, AUS.

Alopecia areata (AA) is an autoimmune nonscarring alopecia that has variable clinical patterns, most commonly patchy disease. We report a case of AA with unusual involvement of the frontal hairline, mimicking frontal fibrosing alopecia (FFA), a form of scarring alopecia. Dermoscopic findings and response to treatment favored a diagnosis of AA. Read More

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February 2021

Complete lung collapse as a rare complication of sarcoidosis-associated mediastinal lymphadenopathy.

Respirol Case Rep 2021 Apr 10;9(4):e00739. Epub 2021 Mar 10.

Department of Pulmonology, Critical Care, and Sleep Medicine Mayo Clinic health System Eau Claire WI USA.

Complete lung collapse associated with sarcoidosis is exceedingly rare. Although lymphoma should be ruled out when patients with mediastinal lymphadenopathy develop lung collapse, sarcoidosis should be considered in the differential, especially when associated with fibrosing mediastinitis. Read More

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Occupational and environmental risk factors of idiopathic pulmonary fibrosis: a systematic review and meta-analyses.

Sci Rep 2021 Mar 2;11(1):4318. Epub 2021 Mar 2.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Hanyang University Guri Hospital, 153, Gyeongchun-ro, Guri-si, Gyeonggi-do, 11923, South Korea.

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial lung disease of unknown cause. It has a high risk of rapid progression and mortality. We conducted a systematic review and meta-analysis to evaluate the risk factor of IPF. Read More

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IgG4-related disease of the thyroid gland.

BMJ Case Rep 2021 Mar 1;14(3). Epub 2021 Mar 1.

Endocrinology, Diabetes, and Metabolism Department, Centro Hospitalar Universitário Lisboa Norte EPE, Lisboa, Portugal.

IgG4-thyroid-related disease (TRD) represents an uncommon spectrum of diseases, with four subcategories established so far, IgG4-related Hashimoto's thyroiditis, fibrosing variant of Hashimoto's thyroiditis, Riedel's thyroiditis and Graves disease with elevated IgG4 levels. We report the case of a 59-year-old woman presenting with painless cervical swelling and hypothyroidism. Thyroid gland was enlarged and distinctively very hard, with reduced mobility. Read More

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Case report--mechanical bowel obstruction with appendicitis without strangulation and leukocytosis.

Ann Med Surg (Lond) 2021 Mar 4;63:102152. Epub 2021 Feb 4.

Department- General Surgery, Institution Khetarpal Hospital, India.

Intestinal obstruction is a common surgical emergency caused by varied conditions. Acute appendicitis is considered as one of the unusual cause of intestinal obstruction especially functional and very few cases of mechanical obstruction. Here we report a Case of 62-years-old male who presented here with a clinical picture of small bowel obstruction. Read More

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A Novel Presentation of Tuberculosis with Intestinal Perforation in a Free-Ranging Australian Sea Lion (Neophoca cinerea).

J Wildl Dis 2021 01;57(1):220-224

Sydney School of Veterinary Science, McMaster Building B14, The University of Sydney, Camperdown, New South Wales 2006, Australia.

We detail a novel presentation of tuberculosis associated with intestinal perforation in an endangered Australian sea lion (Neophoca cinerea) from South Australian waters and confirm the presence of this disease in the region of highest pup production. In February 2017, a 3-yr-old juvenile male died shortly after hauling out at the Kingscote beach on Kangaroo Island. On postmortem examination, we found a mid-jejunal intestinal perforation and partial obstruction (from a strangulating fibrous and granulomatous mesenteric mass), a marked multicentric abdominal fibrosing granulomatous lymphadenitis, and a large volume serosanguinous peritoneal effusion. Read More

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January 2021

Occipital Fibrosing Alopecia in a Young Male: A Case Report.

Skin Appendage Disord 2021 Jan 17;7(1):71-74. Epub 2020 Dec 17.

Department of Dermatology, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.

Introduction: Lichen planopilaris (LPP) is a primary lymphocytic cicatricial alopecia with 3 recognized clinical variants. Lately, LPP clinical spectrum has expanded with new and overlapping clinical variants. First considered as a subtype of LPP affecting postmenopausal women, the increasing worldwide incidence of FFA including atypical lesions in young female and male suggests a different pathomechanism for this disease. Read More

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January 2021

Cutaneous Coinfection of Cytomegalovirus and Accelerated by Immunosuppression.

Case Rep Pathol 2021 29;2021:8819560. Epub 2021 Jan 29.

Department of Diagnostic Pathology, Shimada Municipal Hospital, Shimada, Shizuoka, Japan.

A mildly diabetic 58-year-old male had traumatic ulceration on the left popliteal fossa, and the lesion progressed to a painful 6 cm deep ulcer. After surgical debridement and skin grafting, ulceration recurred. Pyoderma gangrenosum was clinically diagnosed after the first biopsy, indicating a noninfective ulcer. Read More

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January 2021

Pulmonary Manifestations of Rheumatoid Arthritis.

Sr Care Pharm 2021 Feb;36(2):97-103

To describe the case of an 88-yearold male with rheumatoid arthritis who developed pulmonary manifestations. Treatment for his RA previously included various biologics, while at the time of pulmonary consultation included meloxicam, methotrexate, and abatacept. Following chest scans, bronchoscopy, needle biopsy, pulmonary function testing, and a thoracentesis, the diagnosis of pleural effusion and nodules associated with rheumatoid arthritis was determined. Read More

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February 2021

A case of frontal fibrosing alopecia in a 19th century portrait?

Nicolas Kluger

J Cosmet Dermatol 2021 Jan 12. Epub 2021 Jan 12.

Department of Dermatology, Allergology and Venereology, Helsinki University Hospital, Helsinki, Finland.

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January 2021

Ptosis and Miosis Associated with Fibrosing Mediastinitis.

Am J Case Rep 2021 Jan 12;22:e927556. Epub 2021 Jan 12.

Department of Pulmonary Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.

BACKGROUND Fibrosing mediastinitis is a rarely seen, progressive disease. It results from an excessive fibrotic reaction in the mediastinum. We describe a presentation of fibrosing mediastinitis that, to our knowledge, has never been seen before. Read More

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January 2021

Direct hemoperfusion with polymyxin B-immobilized fiber column in a patient with acute exacerbation of idiopathic pulmonary fibrosis.

Acute Crit Care 2020 Nov 13;35(4):302-306. Epub 2020 Apr 13.

Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung disease characterized by dyspnea and a worsening of the lung function. Acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF) are defined by a clinically significant respiratory deterioration, that typically develops in less than 1 month, accompanied by new radiologic abnormalities on high-resolution computed tomography, including diffused and bilateral ground-glass opacification, along with an absence of other obvious clinical etiologies. Recently, AE-IPF has gained significant importance as a major cause of mortality and morbidity. Read More

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November 2020

Primary Cutaneous Cribriform Apocrine Carcinoma.

Am J Case Rep 2021 Jan 2;22:e927744. Epub 2021 Jan 2.

Department of Pharmacology and Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, OH, USA.

BACKGROUND Primary cutaneous cribriform apocrine carcinoma is a histopathological variant of apocrine adenocarcinoma (AA) of the skin, which is a rare, low-grade malignancy. While low-grade in nature, cutaneous cribriform apocrine carcinoma can mimic a metastatic manifestation of a visceral or breast malignancy, and is important to distinguish as primary through clinical history, histology, and immunohistochemical studies, if indicated. CASE REPORT A 56-year-old man with past medical history remarkable for basal cell carcinoma and hypertension presented with a 12-month history of a slowly enlarging, asymptomatic nodule on his right anterior medial lower leg. Read More

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January 2021

Tuberculosis-Induced Bronchiectasis Complicated by Recurrent Respiratory Tract Infections and Renal Amyloidosis: A Classic Revisited.

Ayesha Akram

Cureus 2020 Nov 23;12(11):e11638. Epub 2020 Nov 23.

Internal Medicine, Rawalpindi Medical University, Rawalpindi, PAK.

In this case, a young male patient with a past medical history of adequately treated pulmonary tuberculosis (TB), presented with pedal edema, proteinuria, and evidence of bilaterally enlarged kidneys on renal ultrasound, raising suspicion of renal amyloidosis. Cough, expectoration, severe dyspnea, and high-resolution computed tomographic changes of dilated bronchi paralleled evidence of bronchiectasis exacerbated by perpetual bacterial infection. In view of the laboratory findings and imaging studies, a renal biopsy was done, and it supported the diagnosis of secondary amyloidosis in the kidneys. Read More

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November 2020

A rare diagnostic challenge in a female patient with a rapid recurrent pleural effusion: Autopsy revealed cardiac angiosarcoma with bilateral pleural and pulmonary metastases. A case report.

Int J Surg Case Rep 2021 Jan 17;78:278-283. Epub 2020 Dec 17.

Department of Thoracic Surgery, Lungenklinik Hemer, Hemer, Germany. Electronic address:

Introduction: We present a very rare case with diffuse cardiac angiosarcoma. Because all symptoms are often non-specific, this diagnosis is difficult to establish. To our knowledge this is the first clinical description of this rare disease. Read More

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January 2021

Isotretinoin for the treatment of facial lichen planopilaris: A new indication for an old drug, a case series study.

Clin Case Rep 2020 Dec 5;8(12):2524-2529. Epub 2020 Aug 5.

Pathology Department Faculty of Medicine Isfahan university of Medical Sciences Isfahan Iran.

Despite the little information about the facial papules due to Lichen planopilaris (LPP), we have many cases with facial skin roughness in which histological study has showed LPP. Additionally, in those patients treating for frontal fibrosing alopecia or scalp LPP there was no improvement in facial papules. Read More

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December 2020

Suspensory Ligament Desmitis Caused by sp. in Three Donkeys.

Vet Pathol 2021 Mar 28;58(2):401-404. Epub 2020 Dec 28.

138757The Donkey Sanctuary, Devon, UK.

Three donkeys were presented with progressive lameness and distal suspensory ligament breakdown in multiple limbs. Treatment with nonsteroidal anti-inflammatory drugs was only partially effective and eventually the donkeys were euthanized due to further progression of the lameness and concerns for their welfare. At necropsy, the distal part of the suspensory ligaments in multiple limbs, including the suspensory ligament branches, was markedly thickened, enlarged, and mottled white and brown on cut section. Read More

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Sensitization to benzyl salicylate and other allergens in patients with frontal fibrosing alopecia.

Contact Dermatitis 2021 Jun 26;84(6):423-430. Epub 2021 Jan 26.

Dermatology Department, Hospital Universitario de Guadalajara, Spain.

Background: Contact sensitization is frequent among patients with frontal fibrosing alopecia (FFA) (52%-76%).

Objective: To evaluate the frequency of sensitization/photosensitization in an FFA population.

Methods: A population of FFA patients were patch tested (Spanish Contact Dermatitis Research Group [GEIDAC] baseline; cosmetic and fragrance series), and photopatch tested (sunscreen series). Read More

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Frontal fibrosing alopecia with involvement of the central hair part: distribution of hair loss corresponding to areas of sunscreen application.

Dermatol Online J 2020 Nov 15;26(11). Epub 2020 Nov 15.

Department of Dermatology, The Permanente Medical Group, Vallejo, CA Department of Dermatology, University of California, San Francisco, San Francisco, CA Department of Dermatology, Case Western Reserve University, Cleveland, OH.

Frontal fibrosing alopecia (FFA) typically presents with band-like scarring alopecia in the frontal and temporal hairline along with eyebrow loss. Although this type of hair loss is being seen with increased frequency worldwide, the etiology of the condition is unknown. Studies have suggested a potential environmental role with moisturizers and sunscreens being possible triggers. Read More

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November 2020

Association of Frontal Fibrosing Alopecia with Facial Papules and Lichen Planus Pigmentosus in a Caucasian Woman.

Skin Appendage Disord 2020 Nov 31;6(6):379-383. Epub 2020 Aug 31.

Dermatology Clinic, University of Catania, Catania, Italy.

Introduction: Frontal fibrosing alopecia (FFA) is a lymphocytic primary cicatricial alopecia typically involving the frontotemporal hairline. It may be associated with the presence of facial papules (FP) that clinically appear as noninflammatory, monomorphic, white-yellowish papules. Lichen planus pigmentosus (LPPigm) is characterized by the presence of asymptomatic grayish pigmented macules, predominantly in sun-exposed and flexural areas. Read More

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November 2020