36,847 results match your criteria case demonstrates

Single live birth derived from conjoined oocytes using laser-cutting technique: a case report.

Zygote 2021 Jul 27:1-4. Epub 2021 Jul 27.

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.

The finding of conjoined oocytes is a rare occurrence that accounts for only 0.3% of all human retrieved oocytes. This phenomenon is quite different from that of a traditional single oocyte emanating from one follicle, and may result in dizygotic twins and mosaicism. Read More

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A research agenda on oral health care as a boundary object that unites the perspectives of patients and practitioners.

Health Expect 2021 Jul 27. Epub 2021 Jul 27.

Athena Institute, Faculty of Science, VU University Amsterdam, Amsterdam, The Netherlands.

Context: A research agenda for oral health care was established in the Netherlands using the Dialogue Model. This project served as a case study in which we applied boundary-work theory as a framework to understand boundaries (ie demarcations) between and within groups, and how these boundaries can be overcome.

Objective: To gain insights into the boundaries encountered when setting a research agenda, we analysed how this agenda served as a boundary object (ie circumstances, situations or material that connect actor groups and allow boundary crossing) that facilitated crossing boundaries and uniting the perspectives of patients and practitioners. Read More

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Clinical Reasoning: An Unexpected Response to Therapy in a Patient With HIV and Focal Seizures.

Neurology 2021 Jul 26. Epub 2021 Jul 26.

Department of Internal Medicine, University Teaching Hospital, Lusaka, Zambia

We present the case of a 23-year-old right-handed man who presented to an emergency department in Lusaka, Zambia with new-onset headaches and focal seizures. He was on combination antiretroviral therapy (cART) for HIV and had been started on anti-tuberculous therapy at his local clinic two weeks prior to presentation based on chest x-ray findings. On examination, he had subtle weakness and hyperreflexia in his left upper extremity. Read More

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Tension hydrothorax in a patient with SARS-CoV-2 pneumonitis and pleural .

BMJ Case Rep 2021 Jul 26;14(7). Epub 2021 Jul 26.

Department of Radiology, Royal Free London NHS Foundation Trust, London, UK

Unilateral pleural effusions are uncommonly reported in patients with SARS-CoV-2 pneumonitis. Herein, we report a case of a 42-year-old woman who presented to hospital with worsening dyspnoea on a background of a 2-week history of typical SARS-CoV-2 symptoms. On admission to the emergency department, the patient was severely hypoxic and hypotensive. Read More

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Effectiveness and costs of interventions to reduce the within-farm Toxoplasma gondii seroprevalence on pig farms in the Netherlands.

Porcine Health Manag 2021 Jul 26;7(1):44. Epub 2021 Jul 26.

Vion Food Group, Boxtel, The Netherlands.

Background: The parasite Toxoplasma gondii (T. gondii) is recognized as one of the major foodborne pathogens with a high human disease burden. To control T. Read More

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Acute abdominal pain induced by renal leiomyoma in a young patient: a case report.

J Int Med Res 2021 Jul;49(7):3000605211032802

Department of Urology, Tungwah Hospital of Sun Yat-sen University, Dongguan, China.

Renal leiomyoma is a rare benign mesenchymal tumor of the kidney that predominantly originates from the renal capsule or pelvis. However, because of its nonspecific clinical and imaging features, renal leiomyoma remains poorly characterized and may even lead to radical or partial nephrectomy on the basis of preoperative suspicion of renal carcinoma. We herein present a case involving a 12-year-old boy with acute abdominal pain who was diagnosed with renal leiomyoma based on both clinical imaging and histopathological examination. Read More

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Active case detection methods for crusted scabies and leprosy: A systematic review.

PLoS Negl Trop Dis 2021 Jul 23;15(7):e0009577. Epub 2021 Jul 23.

Menzies School of Health Research, Charles Darwin University and Royal Darwin Hospital, Darwin, Australia.

Background: Crusted scabies is endemic in some remote Aboriginal communities in the Northern Territory (NT) of Australia and carries a high mortality risk. Improvement in active case detection (ACD) for crusted scabies is hampered by a lack of evidence about best practice. We therefore conducted a systematic review of ACD methods for leprosy, a condition with similar ACD requirements, to consider how findings could be informative to crusted scabies detection. Read More

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Fatal intracranial hemorrhage due to infantile acute lymphoblastic leukemia mimicking abusive head trauma.

J Forensic Sci 2021 Jul 23. Epub 2021 Jul 23.

Department of Child Health and Development, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo, Japan.

We report the case of a 2-month-old infant who was found moribund in her crib. Postmortem computed tomography (PMCT) was performed before autopsy. As the baby had a severe subdural hematoma, retinal hemorrhage, and encephalopathy on PMCT, abusive head trauma (AHT) was tentatively diagnosed. Read More

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How I do it? Posterior inferior cerebellar artery-intracranial vertebral artery reimplantation bypass and trapping of dissecting aneurysm involving the proximal posterior inferior cerebellar artery.

Acta Neurochir (Wien) 2021 Jul 23. Epub 2021 Jul 23.

Department of Neurosurgery, Huashan Hospital of Fudan University, No. 12 Wulumuqi Zhong Road, Shanghai, China.

Background: Proximal posterior inferior cerebellar artery (PICA) aneurysms are surgically challenging due to the high variability in the anatomy of the PICA origin, their deep-seated nature, and their entanglement with the lower cranial nerves. Direct or reconstructive clipping may not be achievable if the aneurysm is large, or dissecting, or exhibits atherosclerosis or calcification.

Method: We present a case of a proximal PICA lateral medullary segment (P2) aneurysm that was successfully cured by trapping the aneurysm and reconstructing the PICA using the PICA-intracranial vertebral artery (PICA-V4) via end-to-side reimplantation bypass with the far lateral approach. Read More

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Extracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections.

Commun Biol 2021 Jul 22;4(1):904. Epub 2021 Jul 22.

Department of Laboratory Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China.

Though a definitive link between small colony variants (SCVs) and implant-related staphylococcal infections has been well-established, the specific underlying mechanism remains an ill-explored field. The present study analyzes the role SCVs play in catheter infection by performing genomic and metabolic analyses, as well as analyzing biofilm formation and impacts of glycine on growth and peptidoglycan-linking rate, on a clinically typical Staphylococcus epidermidis case harboring stable SCV, normal counterpart (NC) and nonstable SCV. Our findings reveal that S. Read More

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Timely Use of Venous-Arterial ECMO to Treat Congenital Pediatric Junctional Ectopic Tachycardia: A Case Report.

J Investig Med High Impact Case Rep 2021 Jan-Dec;9:23247096211034045

University of California, Irvine, CA, USA.

Supraventricular tachycardia is the most common tachyarrhythmia in pediatrics. Although postoperative junctional ectopic tachycardia (JET) is a known complication of congenital heart surgery that is typically transient, congenital JET is rare and requires aggressive treatment to maintain hemodynamic stability. We describe the case of a 3-month-old, previously healthy female who presented with heart failure and cardiogenic shock secondary to congenital JET for whom extracorporeal membrane oxygenation (ECMO) provided time for selection of effective therapy. Read More

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Potential public health impact of the adjuvanted recombinant zoster vaccine among people aged 50 years and older in Beijing.

Hum Vaccin Immunother 2021 Jul 26:1-12. Epub 2021 Jul 26.

GSK, Wavre, Belgium.

Herpes zoster (HZ) is a painful, unilateral rash which occurs upon reactivation of latent varicella zoster virus due to age-related immunity decline or immuno-suppression. In 2019, the recombinant zoster vaccine (RZV) was the first vaccine to be approved in China for HZ prevention. This study aimed to estimate the potential public health impact of RZV vaccination, compared with the status quo of no vaccination, in individuals ≥50 years of age (YOA) in Beijing, by adapting the published ZOster ecoNomic Analysis (ZONA) model. Read More

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Intravenous fosfomycin as salvage therapy for osteomyelitis caused by multidrug-resistant Pseudomonas aeruginosa.

Am J Health Syst Pharm 2021 Jul 26. Epub 2021 Jul 26.

Division of Infectious Diseases, University of British Columbia, Vancouver, British Columbia, and Royal Columbian Hospital, New Westminster, British Columbia, Canada.

Purpose: A case of osteomyelitis caused by multidrug-resistant (MDR) Pseudomonas aeruginosa is reported.

Summary: An 84-year-old Caucasian male with an underlying history of type 2 diabetes, peripheral vascular disease, and coronary artery disease had chronic nonhealing wounds on his right foot. Wound care and a course of intravenous (IV) ertapenem with oral ciprofloxacin were ineffective. Read More

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Individualized vocational and educational support and training for youth at clinical high risk for psychosis.

Early Interv Psychiatry 2021 Jul 26. Epub 2021 Jul 26.

Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

Aim: Early intervention for psychosis has been of high interest in the past two decades. Research demonstrates that clinical high risk for psychosis (CHR-p) populations experience impairments in role functioning. Although several vocational and cognitive interventions exist for people living with psychosis, there are no known evidence-based treatments for role functioning difficulties during the CHR-p stage. Read More

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Cytomegalovirus colitis induced segmental colonic hypoganglionosis in an immunocompetent patient: A case report.

World J Clin Cases 2021 Jul;9(20):5631-5636

Department of Gastroenterology, Chonnam National University Hospital, Gwangju 501-757, South Korea.

Background: Cytomegalovirus (CMV) colitis is usually seen in immunocompromised patients with risk factors such as human immunodeficiency virus infection, solid organ transplant, inflammatory bowel disease, or malignancy. Therefore, many clinicians usually do not consider the possibility of CMV colitis in immunocompetent patients. We reported a rare case of segmental colonic hypoganglionosis associated with CMV colitis in an immunocompetent patient. Read More

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Severe hyperbilirubinemia in a neonate with hereditary spherocytosis due to a ankyrin mutation: A case report.

World J Clin Cases 2021 Jul;9(19):5245-5251

Department of Neonatology, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai 200062, China.

Background: Hereditary spherocytosis (HS) is a common type of hemolytic anemia caused by a red cell membrane disorder. HS type 1 (HS1) is mostly caused by mutations in ankyrin (). Newborns with HS1 usually only exhibit anemia and mild jaundice. Read More

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Encapsulating peritoneal sclerosis in liver transplant.

Autops Case Rep 2021 6;11:e2021272. Epub 2021 May 6.

St. Joseph's University Medical Center, Department of Gastroenterology and Hepatology, Paterson, NJ, USA.

Encapsulating peritoneal sclerosis occurs due to chronic irritation of the peritoneal surface resulting in inflammation and fibrosis. Encapsulating peritoneal sclerosis usually occurs in patients requiring peritoneal dialysis (PD); however, it may also occur in liver transplant patients. The fibrosis in encapsulating peritoneal sclerosis could be severe enough to cause small bowel obstruction (SBO). Read More

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Concurrent presentation of brain arteriovenous malformation, peripheral arteriovenous malformation, and cerebellar astrocytoma: Case report.

Interdiscip Neurosurg 2020 Jun 14;20. Epub 2020 Feb 14.

Department of Radiology and Biomedical Imaging, Division of Neurointerventional Radiology, University of California, San Francisco School of Medicine, San Francisco, CA, United States.

Background: We report a rare case of a 19-year-old female progressively affected by a peripheral arteriovenous malformation (pAVM), a midline cerebellar astrocytoma, and a brain arteriovenous malformation (bAVM).

Case Description: She presented with a pulsatile mass on her left cheek, which was classified as a pAVM through angiography. Following treatment with embolization and surgical resection, she returned with enlargement of the mass and imaging incidentally identified a cerebellar astrocytoma. Read More

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Transvenous Onyx Embolization of Carotid-Cavernous Fistulas: Mid- and Long-Term Outcomes.

J Neurol Surg B Skull Base 2021 Jul 15;82(Suppl 3):e278-e284. Epub 2020 May 15.

Advocate Aurora Health, Cerebrovascular Neurosurgery and Comprehensive Stroke Center, Chicago, Illinois, United States.

 Endovascular treatment of carotid-cavernous fistulas (CCFs) has been consistently shown to give excellent results and is currently the mainstay of treatment of these complex vascular pathologies. Onyx is currently the most widely used agent, but there has been concern over high rates of cranial nerve (CN) deficits seen in patients with CCF treated with Onyx and paucity of data on long-term outcomes.  This is a retrospective analysis of patients who underwent transvenous Onyx embolization between 2011 and 2018. Read More

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Applying Environmental Context to Rehabilitation Research Using Geographic Information Systems and Global Positioning Systems Geospatial Technologies.

Rehabil Res Policy Educ 2021 ;35(1):33-50

Boston University, Department of Earth and Environment, Boston, MA, USA.

Background: The International Classification of Functioning, Disability, and Health includes important considerations of environmental context in understanding disability, but the environmental impact is often difficult to measure.

Purpose: Demonstrates the use of Geographic Information Systems (GIS) and Global Positioning Systems (GPS) in rehabilitation research in assessing accessibility and participation; describes how to use these methods, and presents several considerations in using GIS and GPS in research.

Method: Using methods from public health and medical geography, this article describes how to apply GIS and GPS technologies to rehabilitation research to measure community participation and accessibility to resources. Read More

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January 2021

Systemic Thrombolysis for Treatment of Postpartum Saddle Embolism Complicated by Postpartum Hemorrhage: A Case Report and Brief Literature Review.

Case Rep Obstet Gynecol 2021 29;2021:5553296. Epub 2021 Jun 29.

Gulf Coast Educational Consortium/HCA Houston Healthcare West, 12141 Richmond Ave. Houston, TX 77082, USA.

Venous thromboembolic events (VTE), specifically pulmonary embolisms, account for a significant portion of maternal morbidity and mortality. Due to the procoagulant physiological changes that occur, pregnancy and the postpartum period are known risk factors for thromboembolic events. The risk is greatest during the first-week postpartum and remains elevated for up to six weeks as compared to the general population. Read More

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An Attention Mechanism Oriented Hybrid CNN-RNN Deep Learning Architecture of Container Terminal Liner Handling Conditions Prediction.

Bin Li Yuqing He

Comput Intell Neurosci 2021 8;2021:3846078. Epub 2021 Jul 8.

School of Transportation, Fujian University of Technology, Fuzhou 350118, China.

The booming computational thinking and deep learning make it possible to construct agile, efficient, and robust deep learning-driven decision-making support engine for the operation of container terminal handling systems (CTHSs). Within the conceptual framework of computational logistics, an attention mechanism oriented hybrid convolutional neural network and recurrent neural network deep learning architecture (AMO-HCR-DLA) is proposed technically to predict the container terminal liner handling conditions that mainly include liner handling time (LHT) and total working time of quay crane farm (TWT-QCF) for a calling liner. Consequently, the container terminal oriented logistics generalized computation (CTO-LGC) automation and intelligence are established tentatively by AMO-HCR-DLA. Read More

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Religion is Secularised Tradition: Jewish and Muslim Circumcisions in Germany.

Oxf J Leg Stud 2021 14;41(2):431-458. Epub 2020 Dec 14.

British Academy Global Professor, University of Oxford and Affiliate, Max Planck Institute for Comparative and Private International Law. Email:

This article demonstrates that the legal reasoning dominant in modern states secularises traditions by converting them into 'religions'. Using a case study on Germany's recent regulation of male circumcision, we illustrate that religions have (at least) three dimensions: religiosity (private belief, individual right and autonomous choice); religious law (a divinely ordained legal code); and religious groups (public threat). When states restrict traditions within these three dimensions, they construct 'religions' within a secularisation triangle. Read More

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December 2020

Multi-echelon fulfillment warehouse rent and production allocation for online direct selling.

Ann Oper Res 2021 Jul 19:1-25. Epub 2021 Jul 19.

Supply Chain and Logistics Optimization Research Centre, Department of Mechanical, Automotive and Materials Engineering, University of Windsor, Windsor, Canada.

We consider the joint decision problem of renting three types of warehouses and allocating products among the warehouses in an E-commerce supply network, which are supplier, regional, and local warehouses. The research is motivated by a real-world emerging problem in an open warehouse platform (OWP) environment. We focus on the distinct characteristics of a network using an OWP and its underlying cost drivers and propose a nonlinear mixed integer programming model that reflects the interdependencies among inbound transportation, warehousing, delivery, and return, as well as time-sensitive demand. Read More

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Endovascular treatment of a popliteal artery aneurysm via transpedal approach: A case report.

Cardiovasc Revasc Med 2021 Jul 7. Epub 2021 Jul 7.

Mount Sinai Heart, Mount Sinai Morningside Hospital, New York, NY, USA; Sorin Medical Group, New York, NY, USA.

Popliteal artery aneurysm (PAA) has been increasingly treated with endovascular intervention in recent years. However, whether transpedal access can be utilized to treat PAA has not been widely reported. We report a case of successful treatment of a PAA with a covered stent via retrograde transpedal approach in an 80-year male with prohibitive surgical risk who initially failed antegrade approach. Read More

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Novel compound heterozygous TTN variants as a cause of severe neonatal congenital contracture syndrome without cardiac involvement diagnosed with rapid trio exome sequencing.

Neuromuscul Disord 2021 May 24. Epub 2021 May 24.

Clinical Genetics Department, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.

This report focuses on a case of severe congenital myopathy with arthrogryposis without cardiac involvement due to compound heterozygous variants in the TTN gene. The proband presented with severe axial hypotonia, arthrogryposis and severe respiratory insufficiency with ventilator dependence. Electromyogram was abnormal with absent motor responses but preserved sensory nerve responses. Read More

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Active Covid-19 infection and transmission after the first dose of the BNT162b2 mRNA vaccination in Saudi Arabia: A case report.

J Infect Public Health 2021 Jul 13;14(8):1123-1125. Epub 2021 Jul 13.

Department of Medical Microbiology and Immunology, Taibah University, Madinah, Saudi Arabia; Department of Surgery and Cancer, Imperial College London, London, United Kingdom. Electronic address:

A 47-year-old non-smoker male who has received the first dose of the BNT162b2 mRNA Covid-19 vaccine in Saudi Arabia. At day 3 post-vaccination, he tested negative for Covid-19 and travelled to Egypt. On day 12 he developed runny nose, body ache and fever, and he reportedly tested (PCR) negative for Covid-19 Upon his return to Saudi on day 15, his symptoms have worsened and he presented to the Emergency Department, at which he tested positive for Covid-19. Read More

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Physical activity and the risk of SARS-CoV-2 infection, severe COVID-19 illness and COVID-19 related mortality in South Korea: a nationwide cohort study.

Br J Sports Med 2021 Jul 22. Epub 2021 Jul 22.

Department of Pediatrics, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea (the Republic of)

Purpose: To determine the potential associations between physical activity and risk of SARS-CoV-2 infection, severe illness from COVID-19 and COVID-19 related death using a nationwide cohort from South Korea.

Methods: Data regarding 212 768 Korean adults (age ≥20 years), who tested for SARS-CoV-2, from 1 January 2020 to 30 May 2020, were obtained from the National Health Insurance Service of South Korea and further linked with the national general health examination from 1 January 2018 to 31 December 2019 to assess physical activity levels. SARS-CoV-2 positivity, severe COVID-19 illness and COVID-19 related death were the main outcomes. Read More

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Morbidly obese patient with endometrial cancer treated by bariatric surgery to enable cancer treatment.

BMJ Case Rep 2021 Jul 22;14(7). Epub 2021 Jul 22.

School of Medicine, University of Dundee College of Medicine Dentistry and Nursing, Dundee, UK.

The case demonstrates the use of bariatric surgery to improve a patient's candidacy for surgical treatment for endometrial cancer (EC). A 50-year-old morbidly obese woman with early-stage EC was initially treated with levonorgestrel-releasing intrauterine system (52 mg) . She had to reduce her body mass index (BMI) to become eligible for definite EC treatment. Read More

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